Korean Journal of Gastrointestinal Endoscopy 2004;28(1): 1-8.
한국인 대장암의 선별검사로서 대장내시경 검사의 비용-효과 분석
한동수·박준용·윤형란†·배상철*,†
한양대학교 의과대학 내과학교실 소화기내과, *류마티스내과, 류마티스병원 †임상역학·경제연구소
Cost-Effectiveness Analysis of Colon Cancer Screening by Colonosopic Examination in Korea
Dong Soo Han, M.D., Joon Yong Park, M.D., Hyung Ran Yun, M.D.† and Sang Cheol Bae, M.D.*,†
Departments of Medicine, Division of Gastroenterology, *Rheumatology, The Hospital for Rheumatic Disease, †Section for Clinical Epidemiology and Economics, Hanyang University College of Medicine, Seoul, Korea
Abstract
Background/Aims: The mortality of colon cancer is reduced by a proper screening test. Recently, colonoscopic screening was reported more cost-effective than stool occult blood test or sigmoidoscopy in America. In this study, we performed cost-effectiveness analysis of colonoscopy as a colon cancer screening test in Korea by using Markov model. Methods: A hypothetical population of 50 years of age divided into 2 groups. Markov model was applied to those with colonoscopic screening and consecutive polypectomy or without screening. The effect of screening test to the general health was expressed as quality-adjusted life years (QALYs). The variables during the screening test and treatment were regarded carefully by sensitivity analysis. Results: The mean cost estimates for colonoscopic exam was 75,164 won and colon cancer treatment was 10,867,177 won. From the analysis using Markov model, the mean cost required for the screening group was 166,717 won and 76,938 won for non-screening group. The QALY in screening group was 18.49. The incremental cost-effectiveness was 1,097,992 won/QALY. Conclusions: Regular colonoscopic exam requires higher medical cost than non-screening group, with its property of reducing mortality from colorectal cancer, however, colonoscopy is a cost-effective means of colorectal cancer screening. (Korean J Gastrointest Endosc 2004;28:18)