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Intralesional steroid infusion using a spray tube to prevent stenosis after endoscopic submucosal dissection of esophageal cancer
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Atsushi Goto, Takeshi Okamoto, Ryo Ogawa, Kouichi Hamabe, Shinichi Hashimoto, Jun Nishikawa, Taro Takami
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Clin Endosc 2022;55(4):520-524. Published online July 28, 2022
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DOI: https://doi.org/10.5946/ce.2021.262
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Abstract
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- Background
/Aims: Intralesional steroid injections have been administered as prophylaxis for stenosis after esophageal endoscopic submucosal dissection. However, this method carries a risk of potential complications such as perforation because a fine needle is used to directly puncture the postoperative ulcer. We devised a new method of steroid intralesional infusion using a spray tube and evaluated its efficacy and safety.
Methods Intralesional steroid infusion using a spray tube was performed on 27 patients who underwent endoscopic submucosal dissection for superficial esophageal cancer with three-quarters or more of the lumen circumference resected. The presence or absence of stenosis, complications, and the number of endoscopic balloon dilations (EBDs) performed were evaluated after treatment.
Results Although stenosis was not observed in 22 of the 27 patients, five patients had stenosis and dysphagia requiring EBD. The stenosis in these five patients was relieved after four EBDs. No complications related to intralesional steroid infusion using the spray tube were observed.
Conclusions Intralesional steroid infusion using a spray tube is a simple and safe technique that is adequately effective in preventing stenosis Clinical trial number (UMIN000037567).
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Citations
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- Predictors of stricture after endoscopic submucosal dissection of the esophagus and steroids application
Qing-Xia Wang, Yuan Ding, Qi-Liu Qian, Yin-Nan Zhu, Rui-Hua Shi World Journal of Gastrointestinal Endoscopy.2024; 16(9): 509. CrossRef - Development of applicator to deliver hydrogel precursor powder for esophageal stricture prevention after endoscopic submucosal dissection
Takeshi Fujiyabu, Pan Qi, Kenichi Yoshie, Ayano Fujisawa, Yosuke Tsuji, Arvind Kumar Singh Chandel, Athira Sreedevi Madhavikutty, Natsuko F. Inagaki, Seiichi Ohta, Mitsuhiro Fujishiro, Taichi Ito Chemical Engineering Journal.2024; 500: 156742. CrossRef
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Chronological Endoscopic and Pathological Observations in Russell Body Duodenitis
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Atsushi Goto, Takeshi Okamoto, Masaharu Matsumoto, Hiroyuki Saito, Hideo Yanai, Hiroshi Itoh, Isao sakaida
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Clin Endosc 2016;49(4):387-390. Published online March 21, 2016
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DOI: https://doi.org/10.5946/ce.2015.131
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Abstract
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- A 64-year-old man was found to have a nodule in his right lung. He also complained of nausea and abdominal pain during the clinical course. Esophagogastroduodenoscopy revealed a duodenal ulcer associated with severe stenosis and a suspicion of malignancy. However, three subsequent biopsies revealed no evidence of malignancy. The fourth biopsy showed scattered large eosinophilic cells with an eccentric nucleus, leading to a diagnosis of Russell body duodenitis (RBD). RBD is an extremely rare disease, and little is known about its etiology and clinical course. The pathogenesis of RBD is discussed based on our experience with this case.
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Citations
Citations to this article as recorded by
- Russell body duodenitis: a rare condition
Helena González Sánchez, Gloria Meijide Santos, Cristina Fuente Díaz, Olegario Castaño Fernández Revista Española de Enfermedades Digestivas.2024;[Epub] CrossRef - Diagnosis and treatment of gastrointestinal involvement in the late post-COVID
P. L. Shcherbakov, I. R. Valiulin, V. V. Malinovskaya, D. G. Pasechnik, N. V. Ageykina, M. Yu. Shcherbakova Experimental and Clinical Gastroenterology.2023; (11): 234. CrossRef - Surveillance of Russell body inflammation of the digestive tract: a case report and review of literature
Shuai Luo, Xiang Huang, Yao Li, Jinjing Wang Diagnostic Pathology.2022;[Epub] CrossRef - Analysis of clinical and histopathological findings in Russell body gastritis and duodenitis
Sultan Deniz Altindag, Ebru Cakir, Nese Ekinci, Arzu Avci, Fatma Husniye Dilek Annals of Diagnostic Pathology.2019; 40: 66. CrossRef
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