Skip Navigation
Skip to contents

Clin Endosc : Clinical Endoscopy


Author index

Page Path
HOME > Browse Articles > Author index
Bashar Qumseya 1 Article
Predictors of Esophageal Stricture Formation Post Endoscopic Mucosal Resection
Bashar Qumseya, Abraham M. Panossian, Cynthia Rizk, David Cangemi, Christianne Wolfsen, Massimo Raimondo, Timothy Woodward, Michael B. Wallace, Herbert Wolfsen
Clin Endosc 2014;47(2):155-161.   Published online March 31, 2014
AbstractAbstract PDFPubReaderePub

Stricture formation is a common complication after endoscopic mucosal resection. Predictors of stricture formation have not been well studied.


We conducted a retrospective, observational, descriptive study by using a prospective endoscopic mucosal resection database in a tertiary referral center. For each patient, we extracted the age, sex, lesion size, use of ablative therapy, and detection of esophageal strictures. The primary outcome was the presence of esophageal stricture at follow-up. Multivariate logistic regression was used to analyze the association between the primary outcome and predictors.


Of 136 patients, 27% (n=37) had esophageal strictures. Thirty-two percent (n=44) needed endoscopic dilation to relieve dysphagia (median, 2; range, 1 to 8). Multivariate logistic regression analysis showed that the size of the lesion excised is associated with increased odds of having a stricture (odds ratio, 1.6; 95% confidence interval, 1.1 to 2.3; p=0.01), when controlling for age, sex, and ablative modalities. Similarly, the number of lesions removed in the index procedure was associated with increased odds of developing a stricture (odds ratio, 2.3; 95% confidence interval, 1.3 to 4.2; p=0.007).


Stricture formation after esophageal endoscopic mucosal resection is common. Risk factors for stricture formation include large mucosal resections and the resection of multiple lesions on the initial procedure.


Citations to this article as recorded by  
  • Simplified Versus Standard Radiofrequency Ablation Protocols for Barrett's Esophagus: A Systematic Review and Meta-Analysis
    Sagar Shah, Mary Kathryn Roccato, Samuel Ji, Neil Jariwalla, Spencer Kozik, Ronald Dungca Ortizo, Anastasia Chahine, Jennifer M. Kolb, Jason B. Samarasena
    Techniques and Innovations in Gastrointestinal Endoscopy.2022; 24(1): 45.     CrossRef
  • A reliable nomogram model for predicting esophageal stricture after endoscopic submucosal dissection
    Guodong Yang, Zhao Mu, Ke Pu, Yulin Chen, Luoyao Zhang, Haiyue Zhou, Peng Luo, Xiaoying Zhang
    Medicine.2022; 101(5): e28741.     CrossRef
  • Management of esophageal strictures after endoscopic resection for early neoplasia
    Einas Abou Ali, Arthur Belle, Rachel Hallit, Benoit Terris, Frédéric Beuvon, Mahaut Leconte, Anthony Dohan, Sarah Leblanc, Solène Dermine, Lola-Jade Palmieri, Romain Coriat, Stanislas Chaussade, Maximilien Barret
    Therapeutic Advances in Gastroenterology.2021; 14: 175628482098529.     CrossRef
  • Lesion size and circumferential range identified as independent risk factors for esophageal stricture after endoscopic submucosal dissection
    Meihong Chen, Yini Dang, Chao Ding, Jiajia Yang, Xinmin Si, Guoxin Zhang
    Surgical Endoscopy.2020; 34(9): 4065.     CrossRef
  • Risk factors for serious adverse events associated with multiband mucosectomy in Barrett’s esophagus: an international multicenter analysis of 3827 endoscopic resection procedures
    Kamar Belghazi, Norman Marcon, Christopher Teshima, Kenneth K. Wang, Reza V. Milano, Nahid Mostafavi, Michael B. Wallace, Pujan Kandel, Lady Katherine Mejía Pérez, Michael J. Bourke, Farzan Bahin, Martin A. Everson, Rehan Haidry, Gregory G. Ginsberg, Gene
    Gastrointestinal Endoscopy.2020; 92(2): 259.     CrossRef
  • Advances in Endoscopic Resection in the Management of Esophageal Neoplasia
    Don C. Codipilly, Prasad G. Iyer
    Current Treatment Options in Gastroenterology.2020; 18(2): 308.     CrossRef
  • Issues and controversies in esophageal inlet patch
    Adriana Ciocalteu, Petrica Popa, Mircea Ionescu, Dan Ionut Gheonea
    World Journal of Gastroenterology.2019; 25(30): 4061.     CrossRef
  • Radiofrequency ablation in patients with large cervical heterotopic gastric mucosa and globus sensation: Closing the treatment gap
    Ivan Kristo, Erwin Rieder, Matthias Paireder, Katrin Schwameis, Gerd Jomrich, Werner Dolak, Thomas Parzefall, Martin Riegler, Reza Asari, Sebastian F. Schoppmann
    Digestive Endoscopy.2018; 30(2): 212.     CrossRef
  • Endoscopic submucosal dissection for early Barrett’s neoplasia: a meta-analysis
    Dennis Yang, Fei Zou, Sican Xiong, Justin J. Forde, Yu Wang, Peter V. Draganov
    Gastrointestinal Endoscopy.2018; 87(6): 1383.     CrossRef
  • Endoscopic eradication therapy for Barrett’s esophagus: Adverse outcomes, patient values, and cost-effectiveness
    Swarup Kumar, Prasad G. Iyer
    Techniques in Gastrointestinal Endoscopy.2018; 20(2): 75.     CrossRef
  • Recent advances in Barrett's esophagus
    John Inadomi, Hani Alastal, Luigi Bonavina, Seth Gross, Richard H. Hunt, Hiroshi Mashimo, Massimiliano di Pietro, Horace Rhee, Marmy Shah, Salvatore Tolone, David H. Wang, Shao‐Hua Xie
    Annals of the New York Academy of Sciences.2018; 1434(1): 227.     CrossRef
  • Endoscopic therapy for Barrett’s esophagus and early esophageal cancer: Where do we go from here?
    Tavankit Singh, Madhusudhan R Sanaka, Prashanthi N Thota
    World Journal of Gastrointestinal Endoscopy.2018; 10(9): 165.     CrossRef
  • Ablation Therapy for Barrett’s Esophagus: New Rules for Changing Times
    Nour Hamade, Prateek Sharma
    Current Gastroenterology Reports.2017;[Epub]     CrossRef
  • Endoscopic Resection and Ablation for Early-Stage Esophageal Cancer
    Stephanie Worrell, Steven R. DeMeester
    Thoracic Surgery Clinics.2016; 26(2): 173.     CrossRef
  • Advances in the Endoscopic Diagnosis of Barrett Esophagus
    Ashley H. Davis-Yadley, Kevin G. Neill, Mokenge P. Malafa, Luis R. Peña
    Cancer Control.2016; 23(1): 67.     CrossRef
  • Endoscopic mucosal resection
    Joo Ha Hwang, Vani Konda, Barham K. Abu Dayyeh, Shailendra S. Chauhan, Brintha K. Enestvedt, Larissa L. Fujii-Lau, Sri Komanduri, John T. Maple, Faris M. Murad, Rahul Pannala, Nirav C. Thosani, Subhas Banerjee
    Gastrointestinal Endoscopy.2015; 82(2): 215.     CrossRef
  • When Is Pre-Emptive Treatment Necessary after Endoscopic Mucosal Resection of Early Esophageal Neoplasm?
    Hyung Gil Kim
    Clinical Endoscopy.2014; 47(2): 124.     CrossRef
  • 8,359 View
  • 61 Download
  • 23 Web of Science
  • 17 Crossref
Close layer

Clin Endosc : Clinical Endoscopy Twitter Facebook
Close layer