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Modified Endoscopic Ultrasound Needle to Obtain Histological Core Tissue Samples: A Retrospective Analysis
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Munish Ashat, Kaartik Soota, Jagpal S. Klair, Sarika Gupta, Chris Jensen, Arvind R. Murali, Randhir Jesudoss, Rami El-Abiad, Henning Gerke
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Clin Endosc 2020;53(4):471-479. Published online February 5, 2020
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DOI: https://doi.org/10.5946/ce.2019.108
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Abstract
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- Background
/Aims: Endoscopic ultrasound (EUS)-guided fine-needle aspiration is very effective for providing specimens for cytological evaluation. However, the ability to provide sufficient tissue for histological evaluation has been challenging due to the technical limitations of dedicated core biopsy needles. Recently, a modified EUS needle has been introduced to obtain tissue core samples for histological analysis. We aimed to determine (1) its ability to obtain specimens for histological assessment and (2) the diagnostic accuracy of EUS-guided fine-needle biopsy (EUS-FNB) using this needle.
Methods We retrospectively analyzed consecutive cases of FNB using modified EUS needles for 342 lesions in 303 patients. The cytology and histological specimens were analyzed. Diagnostic accuracy was calculated.
Results Adequate cytological and histological assessment was possible in 293/342 (86%) and 264/342 (77%) lesions, respectively. Diagnostic accuracy of the cytological specimen was 294/342 (86%) versus 254/342 (74%) for the histological specimen (p<0.01). Diagnostic accuracy of the combined cytological and histological assessment was 323/342 (94.4%), which was significantly higher than that of both histology alone (p<0.001) and cytology alone (p=0.001).
Conclusions EUS-FNB with the modified EUS needle provided histologic tissue cores in the majority of cases and achieved excellent diagnostic accuracy with few needle passes.
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Citations
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Bo Xu, Qian Lu, Rong Fang, Xiaojuan Dai, Haiyan Xu, Xiangwu Ding, Huawei Gui BMC Gastroenterology.2023;[Epub] CrossRef - Randomized controlled trial comparing the Franseen needle with the Fork-tip needle for EUS-guided fine-needle biopsy
Munish Ashat, Jagpal S. Klair, Sydney L. Rooney, Sagar J. Vishal, Chris Jensen, Nadav Sahar, Arvind R. Murali, Rami El-Abiad, Henning Gerke Gastrointestinal Endoscopy.2021; 93(1): 140. CrossRef
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Including the Sheath Rinse to Improve Cellular Yield in Biliary Brushing Cytology
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Glenda F. Amog-Jones, Subhash Chandra, Chris Jensen, Frederick C. Johlin
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Clin Endosc 2017;50(6):614-616. Published online November 30, 2017
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DOI: https://doi.org/10.5946/ce.2017.113
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Citations
Citations to this article as recorded by 
- Effect of brush rinse on the diagnostic accuracy of biliary stricture evaluation: A multicenter trial
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