Skip Navigation
Skip to contents

Clin Endosc : Clinical Endoscopy

OPEN ACCESS

Author index

Page Path
HOME > Browse Articles > Author index
Search
Diogo T. H. de Moura 2 Articles
Chronic Ménétrier disease leading to gastric cancer in youth
Bruno Salomão Hirsch, Silvia R. Cardoso, Elisa R. Baba, Diogo T. H. de Moura, Manoel Ernesto P. Gonçalves, Rodrigo S. de P. Rocha, Eduardo G. H. de Moura
Clin Endosc 2023;56(1):125-128.   Published online January 18, 2023
DOI: https://doi.org/10.5946/ce.2022.051
PDFPubReaderePub
  • 1,769 View
  • 123 Download
Close layer
Effect of Aspiration Therapy on Obesity-Related Comorbidities: Systematic Review and Meta-Analysis
Pichamol Jirapinyo, Diogo T. H. de Moura, Laura C. Horton, Christopher C. Thompson
Clin Endosc 2020;53(6):686-697.   Published online February 28, 2020
DOI: https://doi.org/10.5946/ce.2019.181
AbstractAbstract PDFPubReaderePub
Background
/Aims: Aspiration therapy (AT) involves endoscopic placement of a gastrostomy tube with an external device that allows patients to drain 30% of ingested calories after meals. Its efficacy for inducing weight loss has been shown. This study aimed to assess the effect of AT on obesity-related comorbidities.
Methods
A meta-analysis of studies that assessed AT outcomes was conducted through December 2018. Primary outcomes were changes in comorbidities at 1 year following AT. Secondary outcomes were the amount of weight loss at up to 4 years and pooled serious adverse events (SAEs).
Results
Five studies with 590 patients were included. At 1 year, there were improvements in metabolic conditions: mean difference (MD) in systolic blood pressure: -7.8 (-10.7 – -4.9) mm Hg; MD in diastolic blood pressure: -5.1 (-7.0 – 3.2) mm Hg; MD in triglycerides: -15.8 (-24.0 – -7.6) mg/dL; MD in high-density lipoprotein: 3.6 (0.7–6.6) mg/dL; MD in hemoglobin A1c (HbA1c): -1.3 (-1.8 – -0.8) %; MD in aspartate transaminase: -2.7 (-4.1 – -1.3) U/L; MD in alanine transaminase: -7.5 (-9.8 – -5.2) U/L. At 1 (n=218), 2 (n=125), 3 (n=46), and 4 (n=27) years, the patients experienced 17.8%, 18.3%, 19.1%, and 18.6% total weight loss (TWL), corresponding to 46.3%, 46.2%, 48.0%, and 48.7% excess weight loss (EWL) (p<0.0001 for all). Subgroup analysis of 2 randomized controlled trials (n=225) showed that AT patients lost more weight than did controls by 11.6 (6.5–16.7) %TWL and 25.6 (16.0–35.3) %EWL and experienced greater improvement in HbA1c and alanine transaminase by 1.3 (0.8–1.8) % and 9.0 (3.9–14.0) U/L. The pooled SAE rate was 4.1%.
Conclusions
Obesity-related comorbidities significantly improved at 1 year following AT. Additionally, a subgroup of patients who continued to use AT appeared to experience significant weight loss that persisted up to at least 4 years.

Citations

Citations to this article as recorded by  
  • Update on Endoscopic Treatments for Obesity
    Fernanda Pessorrusso, Sagar V. Mehta, Shelby Sullivan
    Current Obesity Reports.2024; 13(2): 364.     CrossRef
  • Role of endoscopic duodenojejunal bypass liner in obesity management and glycemic control
    Willian Ferreira Igi, Victor Lira de Oliveira, Ayah Matar, Diogo Turiani Hourneaux de Moura
    Clinical Endoscopy.2024; 57(3): 309.     CrossRef
  • Updates in Endoscopic Bariatric and Metabolic Therapies
    Hammad Qureshi, Naba Saeed, Manol Jovani
    Journal of Clinical Medicine.2023; 12(3): 1126.     CrossRef
  • The Role Bariatric Surgery and Endobariatric Therapies in Nonalcoholic Steatohepatitis
    Aaron Yeoh, Robert Wong, Ashwani K. Singal
    Clinics in Liver Disease.2023; 27(2): 413.     CrossRef
  • Obesity management for cardiovascular disease prevention
    Rama Hritani, Mahmoud Al Rifai, Anurag Mehta, Charles German
    Obesity Pillars.2023; 7: 100069.     CrossRef
  • Overview on the endoscopic treatment for obesity: A review
    Maheeba Abdulla, Nafeesa Mohammed, Jehad AlQamish
    World Journal of Gastroenterology.2023; 29(40): 5526.     CrossRef
  • Endoscopic removal of a weight-loss device with stoma closure using a tack-and-suture device
    Areebah Waseem, Joseph Wawrzynski, Daniel B. Maselli, Ashley Kucera, Chase Wooley, Christopher McGowan
    VideoGIE.2023; 8(11): 441.     CrossRef
  • Effect of Endoscopic Bariatric and Metabolic Therapies on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis
    Pichamol Jirapinyo, Thomas R. McCarty, Russell D. Dolan, Raj Shah, Christopher C. Thompson
    Clinical Gastroenterology and Hepatology.2022; 20(3): 511.     CrossRef
  • Endobariatrics: well past infancy and maturing rapidly
    Shreesh Shrestha, Esha Shrestha, Tilak Shah
    Current Opinion in Gastroenterology.2022; 38(6): 592.     CrossRef
  • Advances in endobariatrics: past, present, and future
    Abhishek Shenoy, Allison R Schulman
    Gastroenterology Report.2022;[Epub]     CrossRef
  • Various Novel and Emerging Technologies in Endoscopic Bariatric and Metabolic Treatments
    Hee Kyong Na, Diogo Turiani Hourneaux De Moura
    Clinical Endoscopy.2021; 54(1): 25.     CrossRef
  • Endoscopic Sleeve Gastroplasty (ESG) for High-Risk Patients, High Body Mass Index (> 50 kg/m2) Patients, and Contraindication to Abdominal Surgery
    Renjie Li, Wilfried Veltzke-Schlieker, Andreas Adler, Maximilian Specht, Wael Eskander, Mahmoud Ismail, Harun Badakhshi, Manoel Passos Galvao, Ricardo Zorron
    Obesity Surgery.2021; 31(8): 3400.     CrossRef
  • Obesity Primer for the Practicing Gastroenterologist
    Pichamol Jirapinyo, Christopher C. Thompson
    American Journal of Gastroenterology.2021; 116(5): 918.     CrossRef
  • Bariatric and metabolic endoscopy: impact on obesity and related comorbidities
    Amit Mehta, Reem Z. Sharaiha
    Therapeutic Advances in Gastrointestinal Endoscopy.2021; 14: 263177452110191.     CrossRef
  • Advanced endoscopic gastrointestinal techniques for the bariatric patient: implications for the anesthesia provider
    Andrew Kim, Joshua A. Spiro, Thomas J. Hatzidais, Norman D. Randolph, Rosie Q. Li, Diana Ayubcha, Mark S. Weiss
    Current Opinion in Anaesthesiology.2021; 34(4): 490.     CrossRef
  • Preparing for the NASH Epidemic: A Call to Action
    Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
    Gastroenterology.2021; 161(3): 1030.     CrossRef
  • Preparing for the NASH epidemic: A call to action
    Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
    Metabolism.2021; 122: 154822.     CrossRef
  • Preparing for the NASH epidemic: A call to action
    Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El‐Serag, Kenneth Cusi
    Obesity.2021; 29(9): 1401.     CrossRef
  • Preparing for the NASH Epidemic: A Call to Action
    Fasiha Kanwal, Jay H. Shubrook, Zobair Younossi, Yamini Natarajan, Elisabetta Bugianesi, Mary E. Rinella, Stephen A. Harrison, Christos Mantzoros, Kim Pfotenhauer, Samuel Klein, Robert H. Eckel, Davida Kruger, Hashem El-Serag, Kenneth Cusi
    Diabetes Care.2021; 44(9): 2162.     CrossRef
  • Endobariatrics and Metabolic Endoscopy: Can We Solve the Obesity Epidemic with Our Scope?
    Jad Farha, Shahem Abbarh, Zadid Haq, Mohamad I. Itani, Andreas Oberbach, Vivek Kumbhari, Dilhana Badurdeen
    Current Gastroenterology Reports.2020;[Epub]     CrossRef
  • 5,739 View
  • 136 Download
  • 19 Web of Science
  • 20 Crossref
Close layer

Clin Endosc : Clinical Endoscopy Twitter Facebook
Close layer
TOP