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Colorectal carcinoma and chronic inflammatory demyelinating polyneuropathy: is there a possible paraneoplastic association?
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Adnan Malik, Faisal Inayat, Muhammad Hassan Naeem Goraya, Gul Nawaz, Ahmad Mehran, Atif Aziz, Saad Saleem
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Clin Endosc 2023;56(2):245-251. Published online July 28, 2021
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DOI: https://doi.org/10.5946/ce.2021.076
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Abstract
PDFPubReaderePub
- A plethora of paraneoplastic syndromes have been reported as remote effects of colorectal carcinoma (CRC). However, there is a dearth of data pertaining to the association of this cancer with demyelinating neuropathies. Herein, we describe the case of a young woman diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP). Treatment with intravenous immunoglobulins and prednisone did not improve her condition, and her neurological symptoms worsened. Subsequently, she was readmitted with exertional dyspnea, lightheadedness, malaise, and black stools. Colonoscopy revealed a necrotic mass in the ascending colon, which directly invaded the second part of the duodenum. Pathologic results confirmed the diagnosis of locally advanced CRC. Upon surgical resection of the cancer, her CIDP showed dramatic resolution without any additional therapy. Patients with CRC may develop CIDP as a type of paraneoplastic syndrome. Clinicians should remain cognizant of this potential association, as it is of paramount importance for the necessary holistic clinical management.
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Omental Patching and Purse-String Endosuture Closure after Endoscopic Full-Thickness Resection in Patients with Gastric Gastrointestinal Stromal Tumors
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Faisal Inayat, Aysha Aslam, Mathew D. Grunwald, Qulsoom Hussain, Abu Hurairah, Shahzad Iqbal
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Clin Endosc 2019;52(3):283-287. Published online October 5, 2018
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DOI: https://doi.org/10.5946/ce.2018.116
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Abstract
PDFPubReaderePub
- Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, primarily arising from the stomach. With the widespread utilization of and technical advancements in endoscopy, gastric GISTs are being increasingly detected at an early stage, enabling complete endoscopic resection. Endoscopic full-thickness resection (EFTR) is an advanced technique that has been recognized as a treatment tool for neoplasms in the digestive tract in selected patients. Although a number of methods are available, closing large iatrogenic defects after EFTR can be a concern in clinical practice. If this potential problem is appropriately solved, patients with gastric GISTs would be suitable candidates for resection utilizing this technique. To our knowledge, this is the first study to propose omental patching and purse-string endosuture closure following EFTR as a feasible endoscopic option in patients with gastric GISTs.
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Citations
Citations to this article as recorded by
- Endoscopic Full Thickness Resection: A Systematic Review
Partha Pal, Mohan Ramchandani, Pradev Inavolu, Duvvuru Nageshwar Reddy, Manu Tandan Journal of Digestive Endoscopy.2022; 13(03): 152. CrossRef - Colon Sparing Endoscopic Full-Thickness Resection for Advanced Colorectal Lesions: Is It Time for Global Adoption?
Zhong-Wei Wu, Chao-Hui Ding, Yao-Dong Song, Zong-Chao Cui, Xiu-Qian Bi, Bo Cheng Frontiers in Oncology.2022;[Epub] CrossRef - Endoscopic Therapy in the Management of Patients With Severe Rectal Bleeding Following Transrectal Ultrasound-Guided Prostate Biopsy: A Case-Based Systematic Review
Adnan Malik, Rizwan Ishtiaq, Muhammad Hassan Naeem Goraya, Faisal Inayat, Vinaya V. Gaduputi Journal of Investigative Medicine High Impact Case Reports.2021;[Epub] CrossRef - Closure techniques in exposed endoscopic full-thickness resection: Overview and future perspectives in the endoscopic suturing era
Antonino Granata, Alberto Martino, Dario Ligresti, Francesco Paolo Zito, Michele Amata, Giovanni Lombardi, Mario Traina World Journal of Gastrointestinal Surgery.2021; 13(7): 645. CrossRef - Use of omental patch and endoscopic closure technique as an alternative to surgery after endoscopic full thickness resection of gastric intestinal stromal tumors: A series of cases
Amit H Sachdev, Shahzad Iqbal, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura World Journal of Clinical Cases.2020; 8(1): 120. CrossRef - Endoscopic full-thickness resection
David Friedel, Xiaocen Zhang, Rani Modayil, Stavros N. Stavropoulos Techniques in Gastrointestinal Endoscopy.2019; 21(1): 19. CrossRef
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