Amyloidosis is characterized by extracellular deposition of insoluble protein fibrils that stain with Congo red application and appear apple green under polarized light. The presenting symptoms result from the involvement of many affected, nonspecific and generalized organ systems. Our patient was an 80-year-old woman with no medical history. She presented with a 2-week history of nausea and vomiting. An esophagogastroduodenoscopy showed erythematous and edematous mucosa on the antrum with pyloric stenosis. Histopathologic examination of the biopsy specimen showed the deposition of amorphous, homogeneous, and acidophilic material in the gastric mucosa. Amyloidal protein was proven by positive Congo red stain. A serum and urine immunfixation electrophoresis showed lambda light chain band. She developed symptoms of repeated greenish color vomiting. A follow-up esophagogastroduodenoscopy showed progressed antral obstruction. However, she refused further evaluation and treatment and was managed conservatively. She later died of disease progression after 34 hospital days.

Citations

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• Digestive Amyloidosis Trends: Clinical, Pathological, and Imaging Characteristics
  Sandica Bucurica, Andreea-Simona Nancoff, Miruna Valeria Moraru, Ana Bucurica, Calin Socol, Daniel-Vasile Balaban, Mihaela Raluca Mititelu, Ionela Maniu, Florentina Ionita-Radu, Mariana Jinga
  Biomedicines.2024; 12(11): 2630.     CrossRef
• A Case of Primary Gastric Amyloidosis with Fulminant Heart Failure
  Seonghun Hong, Young-Woon Chang, Jong Kyu Byun, Min Je Kim, Jung Min Chae, Sun Hee Park, Chi Hyuk Oh, Yong-Koo Park
  The Korean Journal of Gastroenterology.2015; 66(4): 227.     CrossRef