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Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
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Ra Ri Cha, Jin Kyu Cho, Wan Soo Kim, Jin Joo Kim, Jae Min Lee, Sang Soo Lee, Hyun Jin Kim
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Clin Endosc 2019;52(3):278-282. Published online October 5, 2018
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DOI: https://doi.org/10.5946/ce.2018.114
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 Abstract
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- Small cell carcinomas are the most aggressive, highly malignant neuroendocrine tumors; among these, gastric small cell carcinoma (GSCC) is extremely rare. Here we report a case of a patient with primary GSCC, presenting as linitis plastic, who was diagnosed using endoscopic ultrasound (EUS)-guided biopsy. With undiagnosed linitis plastica, an 80-year-old woman was referred to our institution. Abdominal computed tomography revealed irregular wall thickening extending from the gastric body to the antrum. Endoscopy suspected to have Borrmann type IV advanced gastric cancer. EUS of the stomach showed diffuse submucosal thickening of the gastric wall, mainly the antrum. EUS-guided bite-on-bite biopsy confirmed the diagnosis of GSCC. In general, GSCC is difficult to diagnose and careful examination is necessary to determine the therapeutic strategy; however, EUS is particularly helpful in the differential diagnosis of a lesion presenting as linitis plastica.
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Citations
Citations to this article as recorded by  - An online tool for survival prediction of extrapulmonary small cell carcinoma with random forest
Xin Zhang
Frontiers in Oncology.2023;[Epub] CrossRef - Gastric linitis plastica due to signet-ring cell carcinoma with Krukenberg tumors diagnosed by endoscopic ultrasound-guided fine-needle aspiration
Takeshi Okamoto, Hidekazu Suzuki, Katsuyuki Fukuda
Clinical Journal of Gastroenterology.2021; 14(4): 994. CrossRef - A case report of advanced gastric small cell carcinoma with neoadjuvant chemotherapy followed by radical total gastrectomy
Bing Wang, Nanlin Jiao, Lianghui Shi
Asian Journal of Surgery.2020; 43(12): 1205. CrossRef
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