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Katherine R. Black 1 Article
A Single-Center Randomized Controlled Trial Evaluating Timing of Preparation for Capsule Enteroscopy
Katherine R. Black, Wiley Truss, Cynthia I. Joiner, Shajan Peter, Frederick H. Weber
Clin Endosc 2015;48(3):234-238.   Published online May 29, 2015
DOI: https://doi.org/10.5946/ce.2015.48.3.234
AbstractAbstract PDFPubReaderePub
Background/Aims

Intestinal lavage (IL) administration immediately before capsule enteroscopy (CE) is superior to lavage the day before the procedure. We aimed to determine the effect of IL timing on CE diagnostic yield.

Methods

Patients referred for CE were randomized prospectively into two equal groups according to the timing of IL with 2 L of polyethylene glycol solution. Group A and B underwent IL over 2 hours beginning 14 and 4 hours, respectively, before the scheduled CE. The primary outcome measure was preparation quality, measured with a predetermined validated grading scale.

Results

A total of 34 patients were randomized. The frequency of mucosal abnormalities (77% vs. 82%, p=not significant [NS]) and diagnostic yield (47% vs. 53%, p=NS) were similar between the two groups. Moreover, no significant association between the quality of small bowel preparation and the timing at which the purgative for IL was administered was observed (overall fluid transparency, p=0.936; overall mucosal invisibility, p=0.091).

Conclusions

Day-before IL is equivalent to same-day IL in terms of overall preparation quality, proportion of complete studies to cecum, small bowel transit time, frequency of identified mucosal abnormalities, and overall diagnostic yield.

Citations

Citations to this article as recorded by  
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  • Systematic review and meta-analysis: is bowel preparation still necessary in small bowel capsule endoscopy?
    Diana E. Yung, Emanuele Rondonotti, Catherine Sykes, Marco Pennazio, John N. Plevris, Anastastios Koulaouzidis
    Expert Review of Gastroenterology & Hepatology.2017; 11(10): 979.     CrossRef
  • Optimal Bowel Preparation for Video Capsule Endoscopy
    Hyun Joo Song, Jeong Seop Moon, Ki-Nam Shim
    Gastroenterology Research and Practice.2016; 2016: 1.     CrossRef
  • Superiority of the Split-dose PEG Regimen for Small-Bowel Capsule Endoscopy
    Pedro Magalhães-Costa, Joana Carmo, Miguel Bispo, Sofia Santos, Cristina Chagas
    Journal of Clinical Gastroenterology.2016; 50(7): e65.     CrossRef
  • What Is the Optimal Timing of Bowel Preparation for Video Capsule Endoscopy?
    Hyun Joo Song, Ki-Nam Shim
    Clinical Endoscopy.2015; 48(3): 183.     CrossRef
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