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Keyvan Moghissi 1 Article
Photodynamic Therapy (PDT): PDT Mechanisms
Ron R. Allison, Keyvan Moghissi
Clin Endosc 2013;46(1):24-29.   Published online January 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.1.24
AbstractAbstract PDFPubReaderePub

Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how they may be manipulated to improve clinical outcome in cancer patients.

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  • Advances in Liposome-Encapsulated Phthalocyanines for Photodynamic Therapy
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  • Novel nanoparticles prepared from isothiocyanate derivatives for phototherapy of tumor
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  • Combination of Two Photosensitisers in Anticancer, Antimicrobial and Upconversion Photodynamic Therapy
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  • Effect of Hypericin-Mediated Photodynamic Therapy on the Secretion of Soluble TNF Receptors by Oral Cancer Cells
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  • Effect of antimicrobial photodynamic therapy using toluidine blue on dual-species biofilms of Candida albicans and Candida krusei
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  • In vitro anti-tumoral activity of two versatile cationic porphyrins on melanoma cells
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  • Novel Chlorin e6-Curcumin Derivatives as a Potential Photosensitizer: Synthesis, Characterization, and Anticancer Activity
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  • Photodynamic Therapy in Oral Cancer: A Narrative Review
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  • Efficacy of photodynamic therapy in cutaneous leishmaniasis: A systematic review
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  • Mechanism of action of an Ir(iii) complex bearing a boronic acid active as a H2O2-responsive photosensitizer: ROS generation and quinone methide release for GSH scavenging
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  • Advanced Light Source Technologies for Photodynamic Therapy of Skin Cancer Lesions
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  • Photodynamic Therapy Effects on Oral Dysplastic Keratinocyte Cell Cultures: A Systematic Review
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  • Activating MoO3 nanobelts via aqueous intercalation as a near‐infrared type I photosensitizer for photodynamic periodontitis treatment
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  • Polymeric Nanoparticle-Based Photodynamic Therapy for Chronic Periodontitis in Vivo
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    Oncotarget.2016; 7(45): 74259.     CrossRef
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    Oncology Letters.2014; 8(2): 714.     CrossRef
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    Biochimica et Biophysica Acta (BBA) - General Subjects.2013; 1830(10): 4611.     CrossRef
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    F1000Research.2013; 2: 161.     CrossRef
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