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Lars Aabakken 1 Article
Role of Endoscopy in Primary Sclerosing Cholangitis
Purnima Bhat, Lars Aabakken
Clin Endosc 2021;54(2):193-201.   Published online May 8, 2020
AbstractAbstract PDFPubReaderePub
Primary sclerosing cholangitis (PSC) is a progressive disease of the bile ducts that usually results in chronic liver disease often requiring liver transplantation. Endoscopy remains crucial to the care of these patients, although magnetic resonance cholangiopancreatography has replaced endoscopic retrograde cholangiopancreatography (ERCP) as the primary imaging modality for diagnosis. For detection of dysplasia or cholangiocarcinoma, ERCP with intraductal sampling remains compulsory. Moreover, dominant strictures play an important part in the disease development, and management by balloon dilatation or stenting could contribute to long-term prognosis. In addition, endoscopy offers management for adverse events such as bile leaks and anastomotic strictures after liver transplantation. Finally, the special phenotype of inflammatory bowel disease associated with PSC as well as the frequent occurrence of portal hypertension mandates close follow-up with colonoscopy and upper endoscopy. With the emergence of novel techniques, the endoscopist remains a key member of the multidisciplinary team caring for PSC patients.


Citations to this article as recorded by  
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  • Antibiotic prophylaxis and its effect on postprocedural adverse events in endoscopic retrograde cholangiopancreatography for primary sclerosing cholangitis
    Arvid Gustafsson, Lars Enochsson, Bobby Tingstedt, Greger Olsson
    JGH Open.2023; 7(1): 24.     CrossRef
  • Primary sclerosing cholangitis—A long night's journey into day
    Roger W. Chapman
    Clinical Liver Disease.2022; 20(S1): 21.     CrossRef
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