Skip Navigation
Skip to contents

Clin Endosc : Clinical Endoscopy

OPEN ACCESS

Author index

Page Path
HOME > Browse articles > Author index
Search
Madhusudhan R. Sanaka 3 Articles
Endoscopic versus surgical management for colonic volvulus hospitalizations in the United States
Dushyant Singh Dahiya, Abhilash Perisetti, Hemant Goyal, Sumant Inamdar, Amandeep Singh, Rajat Garg, Chin-I Cheng, Mohammad Al-Haddad, Madhusudhan R. Sanaka, Neil Sharma
Clin Endosc 2023;56(3):340-352.   Published online April 17, 2023
DOI: https://doi.org/10.5946/ce.2022.166
Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReaderePub
Background
/Aims: Colonic volvulus (CV), a common cause of bowel obstruction, often requires intervention. We aimed to identify hospitalization trends and CV outcomes in the United States.
Methods
We used the National Inpatient Sample to identify all adult CV hospitalizations in the United States from 2007 to 2017. Patient demographics, comorbidities, and inpatient outcomes were highlighted. Outcomes of endoscopic and surgical management were compared.
Results
From 2007 to 2017, there were 220,666 CV hospitalizations. CV-related hospitalizations increased from 17,888 in 2007 to 21,715 in 2017 (p=0.001). However, inpatient mortality decreased from 7.6% in 2007 to 6.2% in 2017 (p<0.001). Of all CV-related hospitalizations, 13,745 underwent endoscopic intervention, and 77,157 underwent surgery. Although the endoscopic cohort had patients with a higher Charlson comorbidity index, we noted lower inpatient mortality (6.1% vs. 7.0%, p<0.001), mean length of stay (8.3 vs. 11.8 days, p<0.001), and mean total healthcare charge ($68,126 vs. $106,703, p<0.001) compared to the surgical cohort. Male sex, increased Charlson comorbidity index scores, acute kidney injury, and malnutrition were associated with higher odds of inpatient mortality in patients with CV who underwent endoscopic management.
Conclusions
Endoscopic intervention has lower inpatient mortality and is an excellent alternative to surgery for appropriately selected CV hospitalizations.

Citations

Citations to this article as recorded by  
  • Colonic Volvulus
    Samantha L. Savitch, Calista M. Harbaugh
    Clinics in Colon and Rectal Surgery.2024; 37(06): 398.     CrossRef
  • Navigating Abdominal Volvulus: A Comprehensive Review of Management Strategies
    Simran Chauhan, Raju K Shinde, Yashraj Jain
    Cureus.2024;[Epub]     CrossRef
  • Clinicopathological Features of Elderly Patients with Colonic Volvulus
    Mehmet Onur Gul, Selda Oğuz Aşlayan, Kadir Çorbacı, Aytaç Selman, Emre Berat Akçay, Oğuzhan Sunamak, Cebrail Akyüz
    European Journal of Therapeutics.2024; 30(3): 303.     CrossRef
  • Incidental Sigmoid Volvulus after a Ground-level Fall: An Unusual Case Report
    Ziya Karimov, Elchin Shirinov, Gunay Huseynova, Mirhuseyn Mammadov, Meltem Songür Kodik
    Caucasian Medical Journal.2023; 1(3): 36.     CrossRef
  • 2,613 View
  • 168 Download
  • 5 Web of Science
  • 4 Crossref
Close layer
Peroral endoscopic myotomy versus Heller’s myotomy for achalasia hospitalizations in the United States: what does the future hold?
Dushyant Singh Dahiya, Vinay Jahagirdar, Manesh Kumar Gangwani, Muhammad Aziz, Chin-I Cheng, Sumant Inamdar, Madhusudhan R. Sanaka, Mohammad Al-Haddad
Clin Endosc 2022;55(6):826-828.   Published online November 3, 2022
DOI: https://doi.org/10.5946/ce.2022.283
PDFPubReaderePub
  • 2,064 View
  • 120 Download
Close layer
IgG4 Levels in Bile for Distinguishing IgG4-Associated Cholangiopathy from Other Biliary Disorders: A Single Blinded Pilot Study
Udayakumar Navaneethan, Norma G. Gutierrez, Ramprasad Jegadeesan, Preethi GK Venkatesh, Earl Poptic, Madhusudhan R. Sanaka, John J. Vargo, Mansour A. Parsi
Clin Endosc 2014;47(6):555-559.   Published online November 30, 2014
DOI: https://doi.org/10.5946/ce.2014.47.6.555
AbstractAbstract PDFPubReaderePub
Background/Aims

Immunoglobulin G4 (IgG4)-associated cholangiopathy (IAC) is an inflammatory disease and may mimic primary sclerosing cholangitis (PSC), cholangiocarcinoma (CCA), or pancreatic cancer on cholangiography. We investigated whether IgG4 levels in bile aspirated during endoscopic retrograde cholangiopancreatography (ERCP) can distinguish IAC from PSC, CCA, and pancreatic cancer.

Methods

Bile was aspirated directly from the common bile duct during ERCP in patients with IAC prior to steroid therapy. For control purposes, bile was obtained from patients with PSC, CCA, pancreatic cancer, and benign biliary conditions (sphincter of oddi dysfunction/choledocholithiasis).

Results

Biliary IgG4 levels were measured in 54 patients. The median bile IgG4 levels were markedly elevated in patients with IAC (5.5 mg/dL; interquartile range [IQR], 5.1 to 15.6) as compared to patients with benign biliary conditions (0 mg/dL; IQR, 0 to 0.1; p=0.003). The median biliary IgG4 levels in PSC, CCA, and pancreatic cancer were 1.2 (IQR, 0.2 to 3.8), 0.9 (IQR, 0.2 to 3.4), and 0.2 mg/dL (IQR, 0.1 to 0.8), respectively. A cutoff value of 3.8 mg/dL distinguished IAC from PSC and CCA patients with 100% and 76.9% sensitivity and specificity, respectively.

Conclusions

The results of this pilot study suggest that measurement of biliary IgG4 levels may have clinical value in distinguishing patients with IAC from biliary disorders that can mimic IAC.

Citations

Citations to this article as recorded by  
  • Clinical Features, Differential Diagnosis and Treatment of IgG4-Related Sclerosing Cholangitis
    A. K. Guseva, A. V. Okhlobystin
    The Russian Archives of Internal Medicine.2024; 14(2): 96.     CrossRef
  • Review of primary sclerosing cholangitis with increased IgG4 levels
    Charis D Manganis, Roger W Chapman, Emma L Culver
    World Journal of Gastroenterology.2020; 26(23): 3126.     CrossRef
  • Immunoglobulin G4-related cholangiopathy
    Lucas J. Maillette de Buy Wenniger, Ulrich Beuers
    Current Opinion in Gastroenterology.2015; 31(3): 252.     CrossRef
  • Diagnosis of Immunoglobulin G4-Related Sclerosing Cholangitis
    Ji Kon Ryu
    Clinical Endoscopy.2014; 47(6): 476.     CrossRef
  • 6,533 View
  • 61 Download
  • 3 Web of Science
  • 4 Crossref
Close layer

Clin Endosc : Clinical Endoscopy Twitter Facebook
Close layer
TOP