Crohn disease (CD) is a chronic inflammatory bowel disease that affects the entire gastrointestinal tract but is most frequently localized to the large and small bowel. Small bowel endoscopy helps with the differential diagnosis of CD in suspected CD patients. Early diagnosis of CD is preferable for suspected CD conditions to improve chronic inflammatory infiltrates, fibrosis. Small bowel endoscopy can help with the early detection of active disease, thus leading to early therapy before the onset of clinical symptoms of established CD. Some patients with CD have mucosal inflammatory changes not in the terminal ileum but in the proximal small bowel. Conventional ileocolonoscopy cannot detect ileal involvement proximal to the terminal ileum. Small bowel endoscopy, however, can be useful for evaluating these small bowel involvements in patients with CD. Small bowel endoscopy by endoscopic balloon dilation (EBD) enables the treatment of small bowel strictures in patients with CD. However, many practical issues still need to be addressed, such as endoscopic findings for early detection of CD, application compared with other imaging modalities, determination of the appropriate interval for endoscopic surveillance of small bowel lesions in patients with CD, and long-term prognosis after EBD.

Citations

Citations to this article as recorded by  

• Endoscopic stricturotomy and strictureplasty for Crohn’s disease–related duodenal strictures
  Shanshan Wang, Nan Lan, Bo Shen
  iGIE.2024;[Epub]     CrossRef
• Video capsule endoscopy in inflammatory bowel disease
  Kenji J.L. Limpias Kamiya, Naoki Hosoe, Yukie Hayashi, Takaaki Kawaguchi, Kaoru Takabayashi, Haruhiko Ogata, Takanori Kanai
  DEN Open.2022;[Epub]     CrossRef
• Usefulness of magnetic resonance enterography in the clinical decision-making process for patients with inflammatory bowel disease
  Laura Ramos López, Alejandro Hernández Camba, Iago Rodríguez-Lago, Marta Carrillo Palau, Luis Cejas Dorta, Ainara Elorza, Inmaculada Alonso Abreu, Milagros Vela, Alba Hidalgo, Noemi Hernández Álvarez-Builla, G. Esther Rodríguez, Yolanda Rodríguez, Carlos
  Gastroenterología y Hepatología.2020; 43(8): 439.     CrossRef
• Usefulness of magnetic resonance enterography in the clinical decision-making process for patients with inflammatory bowel disease
  Laura Ramos López, Alejandro Hernández Camba, Iago Rodríguez-Lago, Marta Carrillo Palau, Luis Cejas Dorta, Ainara Elorza, Inmaculada Alonso Abreu, Milagros Vela, Alba Hidalgo, Noemi Hernández Álvarez-Builla, G. Esther Rodríguez, Yolanda Rodríguez, Carlos
  Gastroenterología y Hepatología (English Edition).2020; 43(8): 439.     CrossRef
• Different clinical outcomes in Crohn’s disease patients with esophagogastroduodenal, jejunal, and proximal ileal disease involvement: is L4 truly a single phenotype?
  Ren Mao, Rui-Han Tang, Yun Qiu, Bai-Li Chen, Jing Guo, Sheng-Hong Zhang, Xue-Hua Li, Rui Feng, Yao He, Zi-Ping Li, Zhi-Rong Zeng, Rami Eliakim, Shomron Ben-Horin, Min-Hu Chen
  Therapeutic Advances in Gastroenterology.2018; 11: 175628481877793.     CrossRef
• Capsule endoscopy: Current status and role in Crohn’s disease
  Loredana Goran, Ana Maria Negreanu, Ana Stemate, Lucian Negreanu
  World Journal of Gastrointestinal Endoscopy.2018; 10(9): 184.     CrossRef
• Pilot study of endoscopic retrograde 3-dimensional – computed tomography enteroclysis for the assessment of Crohn’s disease
  Hiroki Tanabe, Takahiro Ito, Yuhei Inaba, Katsuyoshi Ando, Yoshiki Nomura, Nobuhiro Ueno, Shin Kashima, Kentaro Moriichi, Mikihiro Fujiya, Toshikatsu Okumura
  European Journal of Radiology Open.2017; 4: 58.     CrossRef
• In-vivo Axial-strain Sonoelastography Helps Distinguish Acutely-inflamed from Fibrotic Terminal Ileum Strictures in Patients with Crohn's Disease: Preliminary Results
  Luca Maria Sconfienza, Flaminia Cavallaro, Valentino Colombi, Luca Pastorelli, Gianeugenio Tontini, Lorenzo Pescatori, Anastassia Esseridou, Edoardo Savarino, Carmelo Messina, Roberto Casale, Giovanni Di Leo, Francesco Sardanelli, Maurizio Vecchi
  Ultrasound in Medicine & Biology.2016; 42(4): 855.     CrossRef
• Video Capsule Endoscopy in Patients with Chronic Abdominal Pain with or without Associated Symptoms: A Retrospective Study
  Jeremy Egnatios, Khushboo Kaushal, Denise Kalmaz, Amir Zarrinpar, Peyman Björklund
  PLOS ONE.2015; 10(4): e0126509.     CrossRef