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Mun Hyuk Seong 2 Articles
Erratum: Extended Spectrum-β-Lactamase or Carbapenemase Producing Bacteria Isolated from Patients with Acute Cholangitis
Ja Chung Goo, Mun Hyuk Seong, Young Kwang Shim, Hee Seung Lee, Jung-Ho Han, Kyeong Seob Shin, Jae-Woon Choi, Sei Jin Youn, Seon Mee Park
Clin Endosc 2012;45(4):453-453.   Published online November 30, 2012
Corrects: Clin Endosc 2012;45(2):155
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Extended Spectrum-β-Lactamase or Carbapenemase Producing Bacteria Isolated from Patients with Acute Cholangitis
Ja Chung Goo, Mun Hyuk Seong, Young Kwang Shim, Hee Seung Lee, Jung-Ho Han, Kyeong Seob Shin, Jae-Woon Choi, Sei Jin Youn, Seon Mee Park
Clin Endosc 2012;45(2):155-160.   Published online June 30, 2012
Correction in: Clin Endosc 2012;45(4):453
AbstractAbstract PDFPubReaderePub

This study assessed the antibiotic resistance organisms isolated from the blood and bile of acute cholangitis and evaluated risk factors associated with them and their impact on clinical outcomes.


The identities and antibiotic resistance profiles of bacteria isolated from 433 cases of acute cholangitis from 346 patients were analyzed. Risk factors and the outcomes of patients infected with them were assessed.


Microorganisms were isolated from 266 of 419 blood cultures and 256 of 260 bile cultures. Isolates from bile and blood were identical in 71% of the cases. A total of 20 extended spectrum-β-lactamase (ESBL)-producers and 4 carbapenemase-producing organisms were isolated from blood, and 34 ESBL-producers and 13 carbapenemase-producers were isolated from bile. Sixty-four (14.8%) cases were infected with any one of these bacteria isolated from blood or bile. Risk factors associated with them in blood were nosocomial infection and prior biliary intervention. In bile, indwelling biliary device was a risk factor associated with them. Antibiotic-resistant bacteria were associated with mortality, independent of other prognostic factors.


ESBL or carbapenemase-producing bacteria were frequently isolated in acute cholangitis patients especially with prior biliary intervention and nosocomial infection. Isolation of antibiotic-resistant bacteria was an independent risk factor of mortality.


Citations to this article as recorded by  
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    Somin Lee, Abeer Qasim, Ahmed Alemam, Misbahuddin Khaja, Anil Dev
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    Han Taek Jeong, Jeong Eun Song, Ho Gak Kim, Jimin Han
    Gut and Liver.2022; 16(6): 985.     CrossRef
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    Young Kyung Yoon, Chisook Moon, Jieun Kim, Sang Taek Heo, Mi Suk Lee, Shinwon Lee, Ki-Tae Kwon, Shin-Woo Kim
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  • Addition of anaerobic coverage for treatment of biliary tract infections: a propensity score-matched cohort study
    Marina Simeonova, Nick Daneman, Philip W Lam, Marion Elligsen
    JAC-Antimicrobial Resistance.2022;[Epub]     CrossRef
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    Jan Bednarsch, Zoltan Czigany, Lara Rosaline Heij, Tom Luedde, Ronald van Dam, Sven Arke Lang, Tom Florian Ulmer, Mathias Walter Hornef, Ulf Peter Neumann
    Scientific Reports.2021;[Epub]     CrossRef
  • Analysis of patterns of bacteremia and 30-day mortality in patients with acute cholangitis over a 25-year period
    Ming Tan, Thøger Gorm Jensen, Stig Lønberg Nielsen, Ove B. Schaffalitzky de Muckadell, Stig Borbjerg Laursen
    Scandinavian Journal of Gastroenterology.2021; 56(5): 578.     CrossRef
  • Increasing burden of biliary tract infection caused by extended‐spectrum beta‐lactamase‐producing organisms in Korea: A nationwide population‐based study
    Dong Kee Jang, Jungmee Kim, Wan Beom Park, Sun Young Yi, Jun Kyu Lee, Won Jae Yoon
    Journal of Gastroenterology and Hepatology.2020; 35(1): 56.     CrossRef
  • Use of microbiological and patient data for choice of empirical antibiotic therapy in acute cholangitis
    Tassilo Kruis, Sarah Güse-Jaschuck, Britta Siegmund, Thomas Adam, Hans-Jörg Epple
    BMC Gastroenterology.2020;[Epub]     CrossRef
  • Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis
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    Journal of Hepato-Biliary-Pancreatic Sciences.2018; 25(1): 3.     CrossRef
  • Appendectomy as a Risk Factor for Bacteremic Biliary Tract Infection Caused by Antibiotic-Resistant Pathogens
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    BioMed Research International.2017; 2017: 1.     CrossRef
  • Urgent ERCP for acute cholangitis reduces mortality and hospital stay in elderly and very elderly patients
    Chan Sun Park, Hee Seok Jeong, Ki Bae Kim, Joung-Ho Han, Hee Bok Chae, Sei Jin Youn, Seon Mee Park
    Hepatobiliary & Pancreatic Diseases International.2016; 15(6): 619.     CrossRef
  • Antibiotic management of complicated intra-abdominal infections in adults: The Asian perspective
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    Annals of Medicine and Surgery.2014; 3(3): 85.     CrossRef
  • A patient presenting with cholangitis due to Stenotrophomonas maltophilia and Pseudomonas aeruginosa successfully treated with intrabiliary colistine
    Pablo N. Pérez, María A. Ramírez, José A. Fernández, Laura Ladrón de Guevara
    Infectious Disease Reports.2014; 6(2): 5147.     CrossRef
  • Is Antibiotic Resistance Microorganism Becoming a Significant Problem in Acute Cholangitis in Korea?
    Sang-Heum Park
    Clinical Endoscopy.2012; 45(2): 111.     CrossRef
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