The practice for endoscopic surveillance of Barrett's oesophagus has evolved from "blind" or random 4 quadrant biopsies (Seattle protocol) to a more "intelligent" targeted biopsy approach. This evolution has been possible due to the rapid advances in endoscopic imaging technology and expertise in the last decade. Previous endoscopes had relatively poor image resolution that often did not allow the subtle mucosal changes associated with dysplastic Barrett's mucosa to be identified. Newer endoscopic imaging techniques available today may allow endoscopists to identify areas of dysplasia or malignancy and target biopsies accordingly. These modalities which include narrow band imaging, chromoendoscopy, autofluorescence imaging, and confocal endomicroscopy as well as a few novel imaging modalities on the horizon will be discussed further.

Citations

Citations to this article as recorded by  

• The Role of Adjunct Imaging in Endoscopic Detection of Dysplasia in Barrett’s Esophagus
  Pujan Kandel, Michael B. Wallace
  Gastrointestinal Endoscopy Clinics of North America.2017; 27(3): 423.     CrossRef
• Red Flag Imaging Techniques in Barrett's Esophagus
  Payal Saxena, Marcia Irene Canto
  Gastrointestinal Endoscopy Clinics of North America.2013; 23(3): 535.     CrossRef
• Preliminary feasibility study using a novel narrow‐band imaging system with dual focus magnification capability in Barrett's esophagus: Is the time ripe to abandon random biopsies?
  Rajvinder Singh, Muhammad Asif Shahzad, Willam Tam, Kenichi Goda, Lawrence Ho Khek Yu, Mitsuhiro Fujishiro, Noriya Uedo, Andrew Ruszkiewicz
  Digestive Endoscopy.2013; 25(S2): 151.     CrossRef