Tuberculosis remains a serious infectious disease with primary features of pulmonary manifestation in Korea. However, duodenal tuberculosis is rare in gastrointestinal cases of extrapulmonary tuberculosis. Here, we report a case of primary duodenal tuberculosis mistaken as a malignant tumor and diagnosed with QuantiFERON-TB GOLD (Cellestis Ltd.) in an immunocompetent male patient.

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• Rare case of duodenal tuberculosis causing gastric outlet obstruction, a case report
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  International Journal of Surgery Case Reports.2023; 105: 108080.     CrossRef
• Primary Extraskeletal Ewing Sarcoma of the Duodenum Revealed by 18F-FDG PET/CT
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• Infections in the gastrointestinal tract that can mimic malignancy
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• Disseminated tuberculosis mimicking abdominal metastatic carcinoma
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• Primary duodenal tuberculosis misdiagnosed as tumor by imaging examination: A case report
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  World Journal of Clinical Cases.2020; 8(24): 6537.     CrossRef
• The role of dual time point PET/CT for distinguishing malignant from benign focal 18F-FDG uptake duodenal lesions
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  Medicine.2018; 97(38): e12521.     CrossRef
• Lymph node tuberculosis mimicking malignancy on 18F-FDG PET/CT in two patients: A case report
  Rui-Lin Ding, Hong-Ying Cao, Yue Hu, Chang-Ling Shang, Fang Xie, Zhen-Hua Zhang, Qing-Lian Wen
  Experimental and Therapeutic Medicine.2017; 13(6): 3369.     CrossRef

Amyloidosis is a group of disorders characterized by the extracellular accumulation of insoluble, fibrillar proteins in various organs and tissues. It is classified, on the basis of the identity of the precursor protein, as primary, secondary, or familial amyloidosis. Gastrointestinal amyloidosis usually presents as bleeding, ulceration, malabsorption, protein loss, and diarrhea. However, gastric amyloidosis with gastric outlet obstruction mimicking linitis plastica is rare. We report a case of gastrointestinal amyloidosis with gastric outlet obstruction in a patient with ankylosing spondylitis. The patient was indicated for subtotal gastrectomy because of the aggravation of obstructive symptoms, but refused the operation and was transferred to another hospital. Three months later, the patient died of aspiration pneumonia during medical treatment.

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• Gastric linitis plastica due to signet-ring cell carcinoma with Krukenberg tumors diagnosed by endoscopic ultrasound-guided fine-needle aspiration
  Takeshi Okamoto, Hidekazu Suzuki, Katsuyuki Fukuda
  Clinical Journal of Gastroenterology.2021; 14(4): 994.     CrossRef
• Systemic amyloidosis with gastrointestinal involvement: Diagnosis from endoscopic and histological views
  Tomoya Iida, Hiroo Yamano, Hiroshi Nakase
  Journal of Gastroenterology and Hepatology.2018; 33(3): 583.     CrossRef
• Amyloidosis of the gastrointestinal tract and the liver: clinical context, diagnosis and management
  Umer Syed, Rafael A. Ching Companioni, Hassan Alkhawam, Aron Walfish
  European Journal of Gastroenterology & Hepatology.2016; 28(10): 1109.     CrossRef
• TNF-α Inhibitor Treatment in an Ankylosing Spondylitis Patient with Secondary Amyloidosis that Manifest with Diarrhea: A Case Report
  Jae Hyun Lee, Jinyoung Moon, Hyun Woo Lee, Sung Hae Chang, Eun Bong Lee, Yeong Wook Song, Eun Young Lee
  The Korean Journal of Medicine.2015; 89(2): 259.     CrossRef

Colorectal cancer is rare in teenagers, especially without known risk factors. Colon cancer in young age is more likely to be diagnosed at advanced-stage, to present unfavorable tumor histology such as mucinous carcinoma, and poor outcome. We report a case of sporadic mucinous adenocarcinoma of the colon in a 19-year-old male patient without any risk factors. He complained of severe left abdominal pain that developed 1 month ago. He had a distended abdomen with severe tenderness on the left lower quadrant. A distal descending colon mass causing mechanical obstruction was observed on abdominal computed tomography. Emergency colonoscopy showed a large, fungating mass obstructing the lumen at 40 cm from the anal verge. Biopsy of the colonic mass suggested a mucinous adenocarcinoma. After decompression by colonic stent, the patient was transferred to the general surgery department for left hemicolectomy. The lesion was confirmed to be a mucinous adenocarcinoma (7.0×4.5 cm). For hereditary nonpolyposis colorectal cancer evaluation, immunohistochemical staining for MLH1 and MSH2 was normal. Reverse transcription polymerase chain reaction analysis did not detect microinstability in any of the markers tested. The patient had no familial history of cancer. Mucinous adenocarcinoma has high frequencies of poor differentiation, advanced tumor stage, loss of mismatch repair gene expression, and increased MUC2 expression. A mucinous histology is considerably more frequent in children and adolescent than in adults. Adequate invasive study is also necessary for young age patients.

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• Clinicopathological features and prognosis analysis of proximal colonic mucinous adenocarcinoma
  Fei Han, Yue Xu, Xiangyu Li, Zhaoxiang Song, Jinlin Xie, Jianning Yao
  Scientific Reports.2024;[Epub]     CrossRef
• NICD3 regulates the expression of MUC5AC and MUC2 by recruiting SMARCA4 and is involved in the differentiation of mucinous colorectal adenocarcinoma
  Xiaodong Yan, Yuan Cheng, Xia Zhang, Yi Hu, Haixia Huang, Jie Ren, Boye Wen, Yuhui Yang, Keyuan Xiao, Wenqing Hu, Wei Wang
  Molecular Oncology.2022; 16(19): 3509.     CrossRef
• Biopsy sampling during self-expandable metallic stent placement in acute malignant colorectal obstruction: a narrative review
  Sigrid Skov Bennedsgaard, Lene Hjerrild Iversen
  World Journal of Surgical Oncology.2021;[Epub]     CrossRef
• Mucinous colorectal adenocarcinoma: clinical pathology and treatment options
  Cong Luo, Shuyi Cen, Guojun Ding, Wei Wu
  Cancer Communications.2019; 39(1): 1.     CrossRef
• Tumor Clinicopathological Characteristics and their Prognostic Value in Mucinous Colorectal Carcinoma
  Cong Luo, Shuyi Cen, Jieer Ying, Xiaohong Wang, Zhixuan Fu, Peng Liu, Wei Wu, Guojun Ding
  Future Oncology.2019; 15(35): 4095.     CrossRef
• Advanced colorectal carcinoma with testicular metastasis in an adolescent: a case report
  Adarsh Pratap Singh, Amit Kumar, Anita Dhar, Shipra Agarwal, Sudhir Bhimaniya
  Journal of Medical Case Reports.2018;[Epub]     CrossRef
• Bone metastasis from colon carcinoma in an 11-year-old boy: radiological features and brief review of the literature
  Marco Colangeli, Carlotta Calamelli, Marco Manfrini, Tommaso Frisoni, Davide Maria Donati
  Skeletal Radiology.2015; 44(5): 743.     CrossRef
• Carcinoma of the colon in children with metastases to the duodenum: Report of two cases and management reflections
  Musa Ibrahim, Adamu Ladan Mu'azu, Kabir Ibrahim Getso, Binta Jibir Wudil, Mohammad Aminu Mohammad, Ali Bala Umar, Umar Shehu Abdullahi, Kefas John Bwala, Nurlan Nurkenovich Akhparov, Aipov R. Rassulbek
  Journal of Pediatric Surgery Case Reports.2014; 2(3): 133.     CrossRef
• Colon carcinoma in childhood: review of the literature with four case reports
  Gangmi Kim, Seung Hyuk Baik, Kang Young Lee, Hyuk Hur, Byung Soh Min, Chuhl Joo Lyu, Nam Kyu Kim
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• Colocolic Intussusception in an Older Child: A Rare Case Report and a Literature Review
  Anupam Das, Lalmalsawma Ralte, A. S. Chawla, S. V. Arya, Anil Kumar, Ravi Saroha, Dheer Singh Kalwaniya
  Case Reports in Surgery.2013; 2013: 1.     CrossRef

Ischemic colitis is generally considered a disease of the elderly. The causes of ischemic colitis include low-flow states due to cardiac dysfunction or hypovolemia and certain medications including estrogen. Here we report a case of ischemic colitis in a 26-year-old woman. She had no specific medical history except taking oral-contraceptives for a long time. The mechanism of estrogen-induced ischemic colitis is not clearly understood. But we recommend that oral-contraceptives should be considered as a cause of ischemic colitis in young women.

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• Drug-Induced Colitis
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• Ischaemic colitis diagnosed by sigmoidoscopy during pregnancy
  Tsubasa Ito, Kazuki Takasaki, Minori Takada, Akira Tomioka
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• Review article: the pharmacological causes of colon ischaemia
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• Injectable Vaginal Hydrogels as a Multi-Drug Carrier for Contraception
  Lei Nie, Peng Zou, Jing Dong, Meng Sun, Peng Ding, Yanting Han, Chingching Ji, Qiuju Zhou, Hongyu Yuan, Jinping Suo
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• Colonic Ischemia After Vaginal Delivery
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• Ischemic enterocolitis and its differential diagnosis
  Georgina Uberti, John R. Goldblum, Daniela S. Allende
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• Oxygen in the regulation of intestinal epithelial transport
  Joseph B. J. Ward, Simon J. Keely, Stephen J. Keely
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• Recurrent ischemic colitis associated with oral contraceptive therapy
  Palaniappan Manickam, Maryconi Jaurigue, Mihaela Batke, Mitchell S. Cappell
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