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Sun Wook Kim 1 Article
Esophageal Involvement of Pemphigus Vulgaris Associated with Upper Gastrointestinal Bleeding
Sooyun Chang, Soo Jung Park, Sun Wook Kim, Moo-Nyun Jin, Jung-Hee Lee, Hyun Ju Kim, Sung Pil Hong, Tae Il Kim
Clin Endosc 2014;47(5):452-454.   Published online September 30, 2014
DOI: https://doi.org/10.5946/ce.2014.47.5.452
AbstractAbstract PDFPubReaderePub

Esophageal involvement of pemphigus vulgaris is rare, and when present, the most common presenting symptoms reported in the medical literature are odynophagia and dysphagia. Here, we present two cases of pemphigus vulgaris presenting with upper gastrointestinal hemorrhage because of esophageal involvement of the disease. In case 1, a 41-year-old female patient with a prior diagnosis of pemphigus vulgaris presented with hematemesis. Esophagogastroduodenoscopy showed diffuse mucosal exfoliation and oozing bleeding of the oropharynx and esophagus. The patient recovered after the administration of high-dose corticosteroids and immunosuppressants. In case 2, a 30-year-old female patient with known pemphigus vulgaris also presented with hematemesis, showing similar endoscopic findings to the first case. She also responded to the same treatment. Esophageal involvement of pemphigus vulgaris responds to high-dose corticosteroids and immunosuppressants. Thus, in patients with pemphigus vulgaris with signs or symptoms of upper gastrointestinal bleeding, an early endoscopy for the evaluation of esophageal involvement is beneficial.

Citations

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