Clinical Endoscopy

Sung-Ae Jung

5 Articles

Comparison of the Diagnostic Ability of Endoscopic Ultrasonography and Abdominopelvic Computed Tomography in the Diagnosis of Gastric Subepithelial Tumors: Sang Yoon Kim, Ki-Nam Shim, Joo-Ho Lee, Ji Young Lim, Tae Oh Kim, A. Reum Choe, Chung Hyun Tae, Hye-Kyung Jung, Chang Mo Moon, Seong-Eun Kim, Sung-Ae Jung; Clin Endosc 2019;52(6):565-573. Published online July 17, 2019; DOI: https://doi.org/10.5946/ce.2019.019

Background
/Aims: Endoscopic ultrasonography (EUS) is the most efficient imaging modality for gastric subepithelial tumors (SETs). However, abdominopelvic computed tomography (APCT) has other advantages in evaluating the characteristics, local extension, or invasion of SETs to adjacent organs. This study aimed to compare the diagnostic ability of EUS and APCT based on surgical histopathology results.
Methods
We retrospectively reviewed data from 53 patients who underwent both EUS and APCT before laparoscopic wedge resection for gastric SETs from January 2010 to December 2017 at a single institution. On the basis of histopathology results, we assessed the diagnostic ability of the 2 tests.
Results
The overall accuracy of EUS and APCT was 64.2% and 50.9%, respectively. In particular, the accuracy of EUS vs. APCT for the diagnosis of gastrointestinal stromal tumors (GISTs), leiomyomas, and ectopic pancreas was 83.9% vs. 74.2%, 37.5% vs. 0.0%, and 57.1% vs. 14.3%, respectively. Most of the incorrect diagnoses with EUS involved hypoechoic lesions originating in the fourth echolayer, with the most common misdiagnosed lesions being GISTs mistaken for leiomyomas and vice versa.
Conclusions
APCT showed a lower overall accuracy than EUS; however, APCT remains a useful modality for malignant/potentially malignant gastric SETs.

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Correlation of preoperative CT features with intra- and postoperative parameters of endoscopic resection in patients with gastric submucosal tumor (1~3 cm)
Yuxiang Chen, Mo Chen, Zhu Wang, Junchao Wu, Jinlin Yang, Li Yang, Kai Deng
Surgical Endoscopy.2025; 39(1): 259. CrossRef
Guidelines in Practice: The Diagnosis and Management of Gastrointestinal Subepithelial Lesions
Brian C. Jacobson, Vanessa M. Shami
American Journal of Gastroenterology.2024; 119(3): 397. CrossRef
Advances in Endoscopic Diagnosis and Treatment of Gastric Neuroendocrine Neoplasms
Xinrui Guo, Xiaohan Zhao, Gang Huang, Yanbo Yu
Digestive Diseases and Sciences.2024; 69(1): 27. CrossRef
Diagnostic Endoscopic Ultrasound (EUS) of the Luminal Gastrointestinal Tract
Giovanna Impellizzeri, Giulio Donato, Claudio De Angelis, Nico Pagano
Diagnostics.2024; 14(10): 996. CrossRef
Current Practice in the Diagnosis and Treatment of Localized Gastric Gastrointestinal Stromal Tumors
Zachary Lee, Divya Mohanraj, Abraham Sachs, Madhavi Kambam, Sandra DiBrito
International Journal of Translational Medicine.2024; 4(3): 387. CrossRef
Efficacy of EUS-guided keyhole biopsies in diagnosing subepithelial lesions of the upper gastrointestinal tract
Sen Verhoeve, Cynthia Verloop, Marco Bruno, Valeska Terpstra, Lydi Van Driel, Lars Perk, Lieke Hol
Endoscopy International Open.2024; 12(10): E1183. CrossRef
Endoscopic Ultrasound and Gastric Sub-Epithelial Lesions: Ultrasonographic Features, Tissue Acquisition Strategies, and Therapeutic Management
Marzia Varanese, Marco Spadaccini, Antonio Facciorusso, Gianluca Franchellucci, Matteo Colombo, Marta Andreozzi, Daryl Ramai, Davide Massimi, Roberto De Sire, Ludovico Alfarone, Antonio Capogreco, Roberta Maselli, Cesare Hassan, Alessandro Fugazza, Alessa
Medicina.2024; 60(10): 1695. CrossRef
III BRAZILIAN CONSENSUS STATEMENT ON ENDOSCOPIC ULTRASOUND
Ricardo Rangel de Paula PESSOA, Alexandre Moraes BESTETTI, Victor Lira de OLIVEIRA, Wladimir Campos de ARAUJO, Simone GUARALDI, Rodrigo Roda RODRIGUES SILVA, Francisco Antonio Araujo OLIVEIRA, Maria Sylvia Ierardi RIBEIRO, Fred Olavo Aragão Andrade CARNEI
Arquivos de Gastroenterologia.2024;[Epub] CrossRef
Enhanced dual-mode imaging: Superior photoacoustic and ultrasound endoscopy in live pigs using a transparent ultrasound transducer
Jaewoo Kim, Dasom Heo, Seonghee Cho, Mingyu Ha, Jeongwoo Park, Joongho Ahn, Minsu Kim, Donggyu Kim, Da Hyun Jung, Hyung Ham Kim, Hee Man Kim, Chulhong Kim
Science Advances.2024;[Epub] CrossRef
The value of contrast-enhanced harmonic endoscopic ultrasound in differential diagnosis and evaluation of malignant risk of gastrointestinal stromal tumors (<50mm)
Jiali Wu, Mengqi Zhuang, Yubao Zhou, Xiang Zhan, Weiwei Xie
Scandinavian Journal of Gastroenterology.2023; 58(5): 542. CrossRef
ACG Clinical Guideline: Diagnosis and Management of Gastrointestinal Subepithelial Lesions
Brian C. Jacobson, Amit Bhatt, Katarina B. Greer, Linda S. Lee, Walter G. Park, Bryan G. Sauer, Vanessa M. Shami
American Journal of Gastroenterology.2023; 118(1): 46. CrossRef
Approach to Small Gastric Subepithelial Lesions
Moon Won Lee, Bong Eun Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(1): 28. CrossRef
Computed tomography features of gastric leiomyoma versus gastric stromal tumor: a case–control study with propensity score matching
Qi Wang, Lijia Wang, Xiaohui Qi, Xiang Liu, Qiao Xie, Yifeng Wang, Gaofeng Shi
Journal of International Medical Research.2023;[Epub] CrossRef
EUS-Guided Diagnosis of Gastric Subepithelial Lesions, What Is New?
Thomas Vasilakis, Dimitrios Ziogas, Georgios Tziatzios, Paraskevas Gkolfakis, Eleni Koukoulioti, Christina Kapizioni, Konstantinos Triantafyllou, Antonio Facciorusso, Ioannis S. Papanikolaou
Diagnostics.2023; 13(13): 2176. CrossRef
The effect of endoscopic ultrasound on the precise selection of endoscopic treatment for submucosal tumors in the upper gastrointestinal tract
Jian-Hua Li, Shu-Min Qin, Tian-Wen Liu, Jun-Qian Chen, Ying-Ting Li
BMC Surgery.2023;[Epub] CrossRef
Systematic Endoscopic Approach for Diagnosing Gastric Subepithelial Tumors
Gwang Ha Kim
Gut and Liver.2022; 16(1): 19. CrossRef
Endoscopic management of subepithelial lesions including neuroendocrine neoplasms: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Pierre H. Deprez, Leon M.G. Moons, Dermot OʼToole, Rodica Gincul, Andrada Seicean, Pedro Pimentel-Nunes, Gloria Fernández-Esparrach, Marcin Polkowski, Michael Vieth, Ivan Borbath, Tom G. Moreels, Els Nieveen van Dijkum, Jean-Yves Blay, Jeanin E. van Hooft
Endoscopy.2022; 54(04): 412. CrossRef
Prediction of Gastric Gastrointestinal Stromal Tumors before Operation: A Retrospective Analysis of Gastric Subepithelial Tumors
Yu-Ning Lin, Ming-Yan Chen, Chun-Yi Tsai, Wen-Chi Chou, Jun-Te Hsu, Chun-Nan Yeh, Ta-Sen Yeh, Keng-Hao Liu
Journal of Personalized Medicine.2022; 12(2): 297. CrossRef
Advancements in the Diagnosis of Gastric Subepithelial Tumors
Osamu Goto, Mitsuru Kaise, Katsuhiko Iwakiri
Gut and Liver.2022; 16(3): 321. CrossRef
DIAGNOSTIC AND THERAPEUTIC MANAGEMENT FOR LEIOMYOMA OF THE UPPER GASTROINTESTINAL TRACT
V. O. Shaprynskyi, Yu. V. Babii
Kharkiv Surgical School.2022; (4-5): 46. CrossRef
A scoring model for radiologic diagnosis of gastric leiomyomas (GLMs) with contrast-enhanced computed tomography (CE-CT): Differential diagnosis from gastrointestinal stromal tumors (GISTs)
Jian-Xia Xu, Qiao-Ling Ding, Yuan-Fei Lu, Shu-Feng Fan, Qin-Pan Rao, Ri-Sheng Yu
European Journal of Radiology.2021; 134: 109395. CrossRef
A Nomogram for Predicting Laparoscopic and Endoscopic Cooperative Surgery during the Endoscopic Resection of Subepithelial Tumors of the Upper Gastrointestinal Tract
Shun-Wen Hsiao, Mei-Wen Chen, Chia-Wei Yang, Kuo-Hua Lin, Yang-Yuan Chen, Chew-Teng Kor, Siou-Ping Huang, Hsu-Heng Yen
Diagnostics.2021; 11(11): 2160. CrossRef
Ultrasonido endoscópico, aplicaciones actuales en tumores sólidos gastrointestinales
Gabriel Alonso Mosquera-Klinger, Jhon Jaime Carvajal Gutiérrez, Alavaro Andrés Gómez Venegas, Sebastián Niño Ramírez, Raúl Cañadas Garrido
Revista Colombiana de Gastroenterología.2020; 35(4): 506. CrossRef
Diagnosis of Gastric Subepithelial Tumors Using Endoscopic Ultrasonography or Abdominopelvic Computed Tomography: Which is Better?
Eun Young Park, Gwang Ha Kim
Clinical Endoscopy.2019; 52(6): 519. CrossRef

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Comparison between the Effectiveness of Oral Phloroglucin and Cimetropium Bromide as Premedication for Diagnostic Esophagogastroduodenoscopy: An Open-Label, Randomized, Comparative Study: Hye-Won Yun, Ki-Nam Shim, Sun-Kyung Na, Jae-In Ryu, Min-Jin Lee, Eun-Mi Song, Seong-Eun Kim, Hye-Kyoung Jung, Sung-Ae Jung; Clin Endosc 2015;48(1):48-51. Published online January 31, 2015; DOI: https://doi.org/10.5946/ce.2015.48.1.48

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Background/Aims

Suppression of gastrointestinal (GI) peristalsis during GI endoscopy commonly requires antispasmodic agents such as hyoscine butylbromide, atropine, glucagon, and cimetropium bromide. This study examined the efficacy of oral phloroglucin for the suppression of peristalsis, its impact on patient compliance, and any associated complications, and compared it with intravenous or intramuscular cimetropium bromide administration.

Methods

This was a randomized, investigator-blind, prospective comparative study. A total of 172 patients were randomized into two groups according to the following medications administered prior to upper endoscopy: oral phloroglucin (group A, n=86), and cimetropium bromide (group B, n=86). The numbers and the degrees of peristalsis events at the antrum and second duodenal portion were assessed for 30 seconds.

Results

A significantly higher number of gastric peristalsis events was observed in group A (0.49 vs. 0.08, p<0.001), but the difference was not clinically significant. No significant difference between both groups was found in the occurrence of duodenal peristalsis events (1.79 vs. 1.63, p=0.569). The incidence of dry mouth was significantly higher with cimetropium bromide than with phloroglucin (50% vs. 15.1%, p<0.001).

Conclusions

Oral phloroglucin can be used as an antispasmodic agent during upper endoscopy, and shows antispasmodic efficacy and adverse effects similar to those of cimetropium bromide.

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Effectiveness of oral phloroglucinol as a premedication for unsedated esophagogastroduodenoscopy: A prospective, double-blinded, placebo-controlled, randomized trial
HyeIn Jung, Hyun Jung Kim, Eun Sung Choi, Ju Yup Lee, Kyung Sik Park, Kwang Bum Cho, Yoo Jin Lee, Lise Lotte Gluud
PLOS ONE.2021; 16(8): e0255016. CrossRef
Cimetropium bromide does not improve polyp and adenoma detection during colonoscope withdrawal
Peel Jung, Su B. Park, Hyung W. Kim, Dae H. Kang, Cheol W. Choi, Su J. Kim, Hyeong S. Nam, Dae G. Ryu, Joung B. Hong, Dong J. Kim
Medicine.2018; 97(25): e11253. CrossRef

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Stricture Occurring after Endoscopic Submucosal Dissection for Esophageal and Gastric Tumors: Gwang Ha Kim, Sam Ryong Jee, Jae Young Jang, Sung Kwan Shin, Kee Don Choi, Jun Haeng Lee, Sang Gyun Kim, Jae Kyu Sung, Suck Chei Choi, Seong Woo Jeon, Byung Ik Jang, Kyu Chan Huh, Dong Kyung Chang, Sung-Ae Jung, Bora Keum, Jin Woong Cho, Il Ju Choi, Hwoon-Yong Jung, Korean ESD Study Group; Clin Endosc 2014;47(6):516-522. Published online November 30, 2014; DOI: https://doi.org/10.5946/ce.2014.47.6.516

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Endoscopic submucosal dissection (ESD) is a widely accepted treatment for early gastric and esophageal cancer. Compared to endoscopic mucosal resection, ESD has the advantage of enabling en bloc removal of tumors regardless of their size. However, ESD can result in a large artificial ulcer, which may lead to a considerable deformity. Circumferential mucosal defects of more than three-fourths the esophageal circumference, long longitudinal mucosal defects (>30 mm), and lesions in the upper esophagus are significant risk factors for the development of post-ESD strictures of the esophagus. In the stomach, a circumferential mucosal defects more than three-fourths in extent and longitudinal mucosal defects >5 cm are risk factors of post-ESD stricture. If scheduled early, regular endoscopic balloon dilation is effective in controlling and preventing post-ESD stricture. Moreover, intralesional steroid injections or oral steroids can achieve remission of dysphagia or reduce the need for repeated endoscopic balloon dilation. However, further study is needed to improve the prevention of stricture formation.

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A novel twin-grasper assisted mucosal inverted closure technique for closing large artificial gastric mucosal defects
Qinbo Cai, Huanjie Chen, Haobin Hou, Wenqing Dong, Lele Zhang, Minxuan Shen, Shaoxiong Yi, Rongman Xie, Xun Hou, Wentong Lan, Yulong He, Dongjie Yang
Surgical Endoscopy.2024; 38(1): 460. CrossRef
The efficacy and safety of snare traction-assisted endoscopic submucosal dissection for circumferential superficial esophageal cancer
Nan Dai, Saif Ullah, Jingwen Zhang, Xiaoyu Wan, Shanshan Zhu, Ping Liu, Changqing Guo, Xinguang Cao
Surgical Endoscopy.2024; 38(6): 3329. CrossRef
Endoscopic Treatment of Early-stage Large Gastric Cancer and Closure with Hand-suturing Technique
Fatih Aslan, Serhat Özer, Orhun Çığ Taşkın
Caucasian Medical Journal.2024; : 29. CrossRef
Risk factors of refractory post-endoscopic submucosal dissection esophageal strictures
Enrique Pérez-Cuadrado Robles, Tom G. Moreels , Hubert Piessevaux , Ralph Yeung, Tarik Aouattah , Pierre H. Deprez
Revista Española de Enfermedades Digestivas.2021;[Epub] CrossRef
Early Esophageal Cancer
Mike T. Wei, Shai Friedland
Gastroenterology Clinics of North America.2021; 50(4): 791. CrossRef
Comparison of general anesthesia and conscious sedation in procedure-related complications during esophageal endoscopic submucosal dissection
Seung Hyun Kim, Yong Seon Choi, Sang Kil Lee, Hanseul Oh, Seung Ho Choi
Surgical Endoscopy.2020; 34(8): 3560. CrossRef
Cyclodextrin Polymer Preserves Sirolimus Activity and Local Persistence for Antifibrotic Delivery over the Time Course of Wound Healing
Nathan A. Rohner, Steve J. Schomisch, Jeffrey M. Marks, Horst A. von Recum
Molecular Pharmaceutics.2019; 16(4): 1766. CrossRef
Endoscopic Treatment for Esophageal Cancer
Yang Won Min
The Korean Journal of Gastroenterology.2018; 71(3): 116. CrossRef
Endoscopic submucosal dissection under general anesthesia for superficial esophageal squamous cell carcinoma is associated with better clinical outcomes
Byeong Geun Song, Yang Won Min, Ra Ri Cha, Hyuk Lee, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J. Kim
BMC Gastroenterology.2018;[Epub] CrossRef
Endoscopic Submucosal Dissection for Superficial Esophageal Neoplasm: A Growing Body of Evidence
Eun Jeong Gong, Hwoon-Yong Jung
Clinical Endoscopy.2016; 49(2): 101. CrossRef
Short-Term Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study
ll Ju Choi, Na Rae Lee, Sang Gyun Kim, Wan Sik Lee, Seun Ja Park, Jae J. Kim, Jun Haeng Lee, Jin-Won Kwon, Seung-Hee Park, Ji Hye You, Ji Hyun Kim, Chul-Hyun Lim, Joo Young Cho, Gwang Ha Kim, Yong Chan Lee, Hwoon-Yong Jung, Ji Young Kim, Hoon Jai Chun, Sa
Gut and Liver.2016; 10(5): 739. CrossRef
Complications of endoscopic resection techniques for upper GI tract lesions
D. Libânio, P. Pimentel-Nunes, M. Dinis-Ribeiro
Best Practice & Research Clinical Gastroenterology.2016; 30(5): 735. CrossRef
An Intractable Caustic Esophageal Stricture Successfully Managed with Sequential Treatment Comprising Incision with an Insulated-Tip Knife, Balloon Dilation, and an Oral Steroid
Woong Ki Lee, Byung Sun Kim, Min A Yang, So Hee Yun, Young Jae Lee, Ji Woong Kim, Jin Woong Cho
Clinical Endoscopy.2016; 49(6): 560. CrossRef
Transplantation of tissue‐engineered cell sheets for stricture prevention after endoscopic submucosal dissection of the oesophagus
Eduard Jonas, Sebastian Sjöqvist, Peter Elbe, Nobuo Kanai, Jenny Enger, Stephan L Haas, Ammar Mohkles‐Barakat, Teruo Okano, Ryo Takagi, Takeshi Ohki, Masakazu Yamamoto, Makoto Kondo, Katrin Markland, Mei Ling Lim, Masayuki Yamato, Magnus Nilsson, Johan Pe
United European Gastroenterology Journal.2016; 4(6): 741. CrossRef
Systematic review: the prevention of oesophageal stricture after endoscopic resection
M. Barret, B. Beye, S. Leblanc, F. Beuvon, S. Chaussade, F. Batteux, F. Prat
Alimentary Pharmacology & Therapeutics.2015; 42(1): 20. CrossRef

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Differential Diagnosis of Inflammatory Bowel Disease: What Is the Role of Colonoscopy?: Sung-Ae Jung; Clin Endosc 2012;45(3):254-262. Published online August 22, 2012; DOI: https://doi.org/10.5946/ce.2012.45.3.254

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Colonoscopy plays a crucial role in the diagnosis, treatment and follow-up monitoring of inflammatory bowel disease (IBD). Practitioners should be well informed of the colonoscopic findings of IBD to prevent the misdiagnosis, overtreatment or delayed treatment. Distinguishing between Crohn's disease and ulcerative colitis is essential in terms of pharmacological treatment, surgical decision-making, and prognosis. But there are still lesions with difficulty in differentiation that approximately 10% of the patients fall into the category of indeterminate colitis. Efforts are needed to carefully select treatment approach appropriate for each patient by providing a precise diagnosis on the extent and degree of lesions as well as to accurately delineate the lesions to assure that they are compared in subsequent rounds of follow-up monitoring in order to allow redetermination and adjustment of the treatment.

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Factors Affecting Adherence to National Colorectal Cancer Screening: A 12-Year Longitudinal Study Using Multi-Institutional Pooled Data in Korea
Dae Sung Kim, Jeeyoung Hong, Kihyun Ryu, Sang Hyuk Lee, Hwanhyi Cho, Jehyeong Yu, Jieun Lee, Jong-Yeup Kim
Journal of Korean Medical Science.2024;[Epub] CrossRef
Acute Cytomegalovirus Colitis Presenting As Exacerbation of Ulcerative Colitis: A Case Report
Varun Daiya, Nishtha Manuja, Sourya Acharya, Sunil Kumar, Sharwari Jaiswal
Cureus.2024;[Epub] CrossRef
Diagnostic Procedures for Inflammatory Bowel Disease: Laboratory, Endoscopy, Pathology, Imaging, and Beyond
Seung Min Hong, Dong Hoon Baek
Diagnostics.2024; 14(13): 1384. CrossRef
lncRNA H-19 and miR-200a implication and frequency of lncRNA H-19 rs2170425 SNP in ulcerative colitis and Crohn’s disease
Ebtsam H. Khalil, Olfat G. Shaker, Nabil A. Hasona
Comparative Clinical Pathology.2023; 32(4): 565. CrossRef
A Review of Colonoscopy in Intestinal Diseases
Seung Hong, Dong Baek
Diagnostics.2023; 13(7): 1262. CrossRef
Impact of Microbiome–Brain Communication on Neuroinflammation and Neurodegeneration
Iris Stolzer, Eveline Scherer, Patrick Süß, Veit Rothhammer, Beate Winner, Markus F. Neurath, Claudia Günther
International Journal of Molecular Sciences.2023; 24(19): 14925. CrossRef
Development and Validation of a Deep Neural Network for Accurate Identification of Endoscopic Images From Patients With Ulcerative Colitis and Crohn's Disease
Guangcong Ruan, Jing Qi, Yi Cheng, Rongbei Liu, Bingqiang Zhang, Min Zhi, Junrong Chen, Fang Xiao, Xiaochun Shen, Ling Fan, Qin Li, Ning Li, Zhujing Qiu, Zhifeng Xiao, Fenghua Xu, Linling Lv, Minjia Chen, Senhong Ying, Lu Chen, Yuting Tian, Guanhu Li, Zho
Frontiers in Medicine.2022;[Epub] CrossRef
Eosinophils in Inflammatory Bowel Disease
Rhiannon T Filippone, Lauren Sahakian, Vasso Apostolopoulos, Kulmira Nurgali
Inflammatory Bowel Diseases.2019; 25(7): 1140. CrossRef
Severe ischemic cytomegalovirus proctocolitis with multiple perforation
Reuban Toby D’cruz, Cheryl Chien-Li Lau, Thomas Paulraj Thamboo
Archives of Virology.2018; 163(7): 1927. CrossRef
Indicators of suboptimal biologic therapy over time in patients with ulcerative colitis and Crohn's disease in the United States
Haridarshan Patel, Trevor Lissoos, David T. Rubin, Shree Ram Singh
PLOS ONE.2017; 12(4): e0175099. CrossRef
Combining TNFSF15 and ASCA IgA can be used as a predictor for the stenosis/perforating phenotype of Crohn's disease
Chien‐Chih Tung, Jau‐Min Wong, Wen‐Chung Lee, Heng‐Hsiu Liu, Chin‐Hao Chang, Ming‐Chu Chang, Yu‐Ting Chang, Ming‐Jium Shieh, Cheng‐Yi Wang, Shu‐Chen Wei
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Highlights of the 48th Seminar of Korean Society of Gastrointestinal Endoscopy
Kwang An Kwon, Il Ju Choi, Eun Young Kim, Seok Ho Dong, Ki Baik Hahm
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The Clinical Meaning of Benign Colon Uptake in ¹⁸F-FDG PET: Comparison with Colonoscopic Findings: Sun Hee Roh, Sung-Ae Jung, Seong-Eun Kim, Hye-In Kim, Min Jin Lee, Chung Hyun Tae, Ju Young Choi, Ki-Nam Shim, Hye-Kyung Jung, Tae Hun Kim, Kwon Yoo, Il Hwan Moon, Bom Sahn Kim; Clin Endosc 2012;45(2):145-150. Published online June 30, 2012; DOI: https://doi.org/10.5946/ce.2012.45.2.145

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Background/Aims

Benign colon ¹⁸F-fluorodeoxyglucose (FDG) uptake is frequently observed in asymptomatic individuals. Aims of this study were to investigate the benign colon uptake by whole body FDG-positron emission tomography (PET) in asymptomatic adults and to correlate those results with colonoscopic and histologic findings.

Methods

Among 3,540 subjects who had undergone FDG-PET, 43 subjects who were diagnosed to have benign colon uptake in FDG-PET and underwent colonoscopy were retrospectively reviewed. Subjects were classified as diffuse or focal groups based on their FDG uptake patterns. PET results were analyzed together with colonoscopic and histologic findings.

Results

Forty-three subjects showed benign colon uptake in FDG-PET; 28 of them were shown as the diffuse group, while other 15 subjects were classified as the focal group. Five subjects among those showed diffuse uptake were diagnosed as adenoma. Seven among 15 subjects who showed focal uptake were diagnosed as adenocarcinoma (n=2), adenoma (n=3), or non-neoplastic polyp (n=2). Positive predictive values were 25% in the diffuse group and 47% in the focal group.

Conclusions

We recommend that patients showing benign FDG uptake in the colon should be further evaluated by colonoscopy, especially for patients with focal FDG uptake.

Citations

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Abdominal Radiology.2020; 45(4): 1018. CrossRef
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S. J. Kousgaard, O. Thorlacius-Ussing
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Adriana Tamburello, Giorgio Treglia, Domenico Albano, Francesco Bertagna, Luca Giovanella
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T. Cassou-Mounat, M. Terroir, F. Adam-Tariel, R. Perdrisot, I. Biancheri-Mounicq
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Juliette Vella-Boucaud, Dimitri Papathanassiou, Olivier Bouche, Alain Prevost, Thibault Lestra, Sandra Dury, Hervé Vallerand, Jeanne-Marie Perotin, Claire Launois, Louis Boissiere, Mathilde Brasseur, François Lebargy, Gaëtan Deslee
BMC Pulmonary Medicine.2015;[Epub] CrossRef
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Serdal ÇAKMAK, Aliye SOYLU, İsa SEVİNDİR, Yıldız OKUTURLAR, Mustafa UÇAR
Endoskopi Gastrointestinal.2015; 22(2): 29. CrossRef
Rifaximin suppresses background intestinal 18F-FDG uptake on PET/CT scans
Elisa Franquet, Mathew R. Palmer, Anne E. Gifford, Daryl J. Selen, Yih-Chieh S. Chen, Neda Sedora-Roman, Robin M. Joyce, Gerald M. Kolodny, Alan C. Moss
Nuclear Medicine Communications.2014; 35(10): 1026. CrossRef
Pelvis
Andres Kohan, Norbert E. Avril
PET Clinics.2014; 9(2): 185. CrossRef
Is It Useful to Perform Additional Colonoscopy to Detect Unmatched Lesion between Positron Emission Tomography/Computed Tomography and Colonoscopy?
Chang Yong Yun, Jun-Oh Jung, Seong O Suh, Ji Won Yoo, Yu Mi Oh, Soo Min Ahn, Hyoung Hun Sim, Eun Sil Kim, Ji Yoon Bae
The Korean Journal of Gastroenterology.2013; 61(6): 319. CrossRef
Lesion Location in Clinical Significance of Incidental Colorectal FDG Uptake
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Benign Colonic18F-FDG Uptake on Whole-Body FDG-PET Scan
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Clinical Endoscopy.2012; 45(2): 109. CrossRef

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