Clinical Endoscopy

Sunguk Jang

5 Articles

Single Use (Disposable) Duodenoscope: Recent Development and Future: Kihyun Ryu, Sunguk Jang; Clin Endosc 2022;55(2):191-196. Published online June 22, 2021; DOI: https://doi.org/10.5946/ce.2021.075

Unlike simple forward-viewing endoscopes such as gastroscope or colonoscope, duodenoscope houses much more complex design to fulfil its function. This design differences leave duodenoscopes more prone to contamination from inadequate disinfection process and potential dissemination of pathogens. Recent reports on dissemination of infection through the duodenoscope mandated an overhaul of duodenoscope utilization including development of a disposable duodenoscope. This article reviews the current state of disposable duodenoscope development, including reported early efficacy as well as its future direction and utilization.

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Materials Science Toolkit for Carbon Footprint Assessment: A Case Study for Endoscopic Accessories of Common Use
Rubén Martín-Cabezuelo, Guillermo Vilariño-Feltrer, Alberto J. Campillo-Fernández, Vicente Lorenzo-Zúñiga, Vicente Pons, Pedro López-Muñoz, Isabel Tort-Ausina
ACS Environmental Au.2024; 4(1): 42. CrossRef
The Evolution of Spinal Endoscopy: Design and Image Analysis of a Single-Use Digital Endoscope Versus Traditional Optic Endoscope
Shih-Hao Cheng, Yen-Tsung Lin, Hsin-Tzu Lu, Yu-Chuan Tsuei, William Chu, Woei-Chyn Chu
Bioengineering.2024; 11(1): 99. CrossRef
Cost-effectiveness Analysis of Single-Use Duodenoscope Applied to Endoscopic Retrograde Cholangiopancreatography
David Nicolás-Pérez, Antonio Zebenzuy Gimeno-García, Rafael Joaquín Romero-García, Iván Castilla-Rodríguez, Manuel Hernandez-Guerra
Pancreas.2024; 53(4): e357. CrossRef
ERCP with single-use disposable duodenoscopes in four different set-ups
Ronja Lagström, Svend Knuhtsen, Trine Stigaard, Mustafa Bulut
BMJ Case Reports.2023; 16(2): e251514. CrossRef
Good Practices on Endoscope Reprocessing in Italy: Findings of a Nationwide Survey
Michela Scarpaci, Tommaso Cosci, Benedetta Tuvo, Alessandra Guarini, Teresa Iannone, Angelo Zullo, Beatrice Casini
International Journal of Environmental Research and Public Health.2022; 19(19): 12082. CrossRef

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Risk Stratification in Cancer Patients with Acute Upper Gastrointestinal Bleeding: Comparison of Glasgow-Blatchford, Rockall and AIMS65, and Development of a New Scoring System: Matheus Cavalcante Franco, Sunguk Jang, Bruno da Costa Martins, Tyler Stevens, Vipul Jairath, Rocio Lopez, John J. Vargo, Alan Barkun, Fauze Maluf-Filho; Clin Endosc 2022;55(2):240-247. Published online January 21, 2022; DOI: https://doi.org/10.5946/ce.2021.115

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Background
/Aims: Few studies have measured the accuracy of prognostic scores for upper gastrointestinal bleeding (UGIB) among cancer patients. Thereby, we compared the prognostic scores for predicting major outcomes in cancer patients with UGIB. Secondarily, we developed a new model to detect patients who might require hemostatic care.
Methods
A prospective research was performed in a tertiary hospital by enrolling cancer patients admitted with UGIB. Clinical and endoscopic findings were obtained through a prospective database. Multiple logistic regression analysis was performed to gauge the power of each score.
Results
From April 2015 to May 2016, 243 patients met the inclusion criteria. The AIMS65 (area under the curve [AUC] 0.85) best predicted intensive care unit admission, while the Glasgow-Blatchford score best predicted blood transfusion (AUC 0.82) and the low-risk group (AUC 0.92). All scores failed to predict hemostatic therapy and rebleeding. The new score was superior (AUC 0.74) in predicting hemostatic therapy. The AIMS65 (AUC 0.84) best predicted in-hospital mortality.
Conclusions
The scoring systems for prognostication were validated in the group of cancer patients with UGIB. A new score was developed to predict hemostatic therapy. Following this result, future prospective research should be performed to validate the new score.

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Comparative diagnostic utility of Rockall and Glasgow-Blatchford scores in non-variceal upper gastrointestinal bleeding: a systematic review and meta-analysis
Landon Kozai, Arvin Tan, Kevin Nebrejas, Yoshito Nishimura
European Journal of Gastroenterology & Hepatology.2025; 37(2): 161. CrossRef
Endoscopic Management of Tumor Bleeding
Frances Dang, Marc Monachese
Gastrointestinal Endoscopy Clinics of North America.2024; 34(1): 155. CrossRef
Clinical significance of D-dimer, antithrombin III, and Helicobacter pylori infection in acute upper gastrointestinal bleeding
Cong-Biao Cheng, Na Li
World Chinese Journal of Digestology.2024; 32(7): 501. CrossRef
The Accuracy of Pre-Endoscopic Scores for Mortality Prediction in Patients with Upper GI Bleeding and No Endoscopy Performed
Sergiu Marian Cazacu, Dragoș Ovidiu Alexandru, Răzvan-Cristian Statie, Sevastița Iordache, Bogdan Silviu Ungureanu, Vlad Florin Iovănescu, Petrică Popa, Victor Mihai Sacerdoțianu, Carmen Daniela Neagoe, Mirela Marinela Florescu
Diagnostics.2023; 13(6): 1188. CrossRef
Progress in the Evaluation of Acute Upper Gastrointestinal Bleeding with AIMS65 Scoring System
莉王
Advances in Clinical Medicine.2023; 13(05): 8163. CrossRef
Interpretations of the Role of Plasma Albumin in Prognostic Indices: A Literature Review
Kim Oren Gradel
Journal of Clinical Medicine.2023; 12(19): 6132. CrossRef

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Endoscopic Hemostasis for Non-Variceal Upper Gastrointestinal Bleeding: New Frontiers: Adam Kichler, Sunguk Jang; Clin Endosc 2019;52(5):401-406. Published online July 16, 2019; DOI: https://doi.org/10.5946/ce.2018.103

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Non-variceal upper gastrointestinal bleeding (NVUGIB) refers to blood loss from the gastrointestinal tract proximal to the ligament of Treitz due to lesions that are non-variceal in origin. The distinction of the bleeding source as non-variceal is important in numerous aspects, but none more so than endoscopic approaches for successful hemostasis. When a patient presents with acute overt blood loss, NVUGIB is a medical emergency, which requires immediate intervention. There have been major strides in pharmacologic and endoscopic interventions for successful induction and remission of hemostasis in the last two decades. Despite achieving tangible improvements, the burden of the disease and the consequent mortality remain high. To address endoscopic outcomes better, several new technologies have emerged and have been subsequently incorporated to the armamentarium of hemostatic tools. This study aims to provide a succinct review on novel technologies for endoscopic hemostasis.

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Clinical characteristics of acute non-varicose upper gastrointestinal bleeding and the effect of endoscopic hemostasis
Xiao-Juan Wang, Yu-Peng Shi, Li Wang, Ya-Ni Li, Li-Juan Xu, Yue Zhang, Shuang Han
World Journal of Clinical Cases.2024; 12(9): 1597. CrossRef
MODERN TRENDS IN ENDOSCOPIC HEMOSTASIS IN PATIENTS WITH EROSIVE-ULCERATIVE GASTROINTESTINAL BLEEDING WITH PREROGATIVE USE OF ARGON PLASMA COAGULATION AND TAKING INTO ACCOUNT THE SPECIAL CONDITIONS OF THE ENDOSCOPY DEPARTMENT IN WARTIME
V. V. Boiko, V. H. Hroma, I. A. Taraban, Y. V. Hroma
Kharkiv Surgical School.2024; (1): 62. CrossRef
Neutrophil-lymphocyte ratio predict outcome of upper gastrointestinal bleeding in emergency
Xinyi Chen, Xinqun Li, Guangju Zhao, Wen Xu
Frontiers in Medicine.2024;[Epub] CrossRef
Progress in Diagnosis and Treatment of Acute Upper Gastrointestinal Bleeding
泗云李
Advances in Clinical Medicine.2024; 14(08): 1674. CrossRef
Endoscopic Hemostasis and Antithrombotic Management
Jamie Bering, Mashal J. Batheja, Neena S. Abraham
Gastroenterology Clinics of North America.2024; 53(4): 573. CrossRef
UI-EWD hemostatic powder in the management of refractory lower gastrointestinal bleeding: a multicenter study
Gyeol Seong, Boram Cha, Jongbeom Shin, Sung Min Kong, Ji Taek Hong, Kye Sook Kwon
Scandinavian Journal of Gastroenterology.2024; 59(10): 1172. CrossRef
Short Peptide Nanofiber Biomaterials Ameliorate Local Hemostatic Capacity of Surgical Materials and Intraoperative Hemostatic Applications in Clinics
Zehong Yang, Lihong Chen, Ji Liu, Hua Zhuang, Wei Lin, Changlong Li, Xiaojun Zhao
Advanced Materials.2023;[Epub] CrossRef
Accessory Splenic Artery Causing Massive Gastrointestinal Bleed
Priyesh Patel, Pravallika Chadalavada, Amandeep Singh, Ram Kishore Gurajala, Jean-Paul Achkar
ACG Case Reports Journal.2021; 8(3): e00550. CrossRef
Diode Laser—Can It Replace the Electrical Current Used in Endoscopic Submucosal Dissection? (with Video)
Yunho Jung, Gwang Ho Baik, Weon Jin Ko, Bong Min Ko, Seong Hwan Kim, Jin Seok Jang, Jae-Young Jang, Wan-Sik Lee, Young Kwan Cho, Sun Gyo Lim, Hee Seok Moon, In Kyung Yoo, Joo Young Cho
Clinical Endoscopy.2021; 54(4): 555. CrossRef
In Vivo Investigation of Noncontact Rapid Photothermal Hemostasis on Venous and Arterial Bleeding
Myeongjin Kim, Van Gia Truong, Sungwon Kim, Hyejin Kim, Thomas Hasenberg, Hyun Wook Kang
IEEE Transactions on Biomedical Engineering.2021; 68(9): 2689. CrossRef
Comparison of high and low-dose epinephrine & endoclip application in peptic ulcer bleeding
Tamer Akay, Metin Leblebici
Medicine.2021; 100(52): e28480. CrossRef
Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature
Claudio Giovanni De Angelis, Pablo Cortegoso Valdivia, Stefano Rizza, Ludovica Venezia, Felice Rizzi, Marcantonio Gesualdo, Giorgio Maria Saracco, Rinaldo Pellicano
Journal of Clinical Medicine.2020; 9(3): 866. CrossRef
Preparation and Study of Hemostatic Materials Based on Chitosan and Chitin Nanofibrils
E. N. Maevskaia, E. N. Dresvyanina, A. S. Shabunin, I. P. Dobrovol’skaya, M. B. Paneyah, A. M. Fediuk, P. L. Sushchinskii, G. P. Smirnov, V. E. Yudin, E. V. Zinoviev
Nanotechnologies in Russia.2020; 15(7-8): 466. CrossRef

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Future Perspectives on Endoscopic Ultrasonography-Guided Therapy for Pancreatic Neoplasm: Woo Hyun Paik, Sang Hyub Lee, Sunguk Jang; Clin Endosc 2018;51(3):229-234. Published online May 18, 2018; DOI: https://doi.org/10.5946/ce.2018.063

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Endoscopic ultrasonography (EUS)-guided therapy with ethanol injection or catheter-based radiofrequency ablation for pancreatic neoplasm has been conducted as a potential alternate treatment modality for patients who are not eligible for surgery. On the basis of the limited number of studies available, EUS-guided ablation therapy with the aforementioned methods for small pancreatic neoplasms has demonstrated promising technical feasibility and safety profiles. To be considered as a legitimate alternative option to surgery, however, EUS-guided ablation therapy must provide a long-term efficacy profile along with the consensus among experts regarding its treatment parameter. This review focuses on the clinical issues and future perspectives of EUS-guided therapy for pancreatic neoplasm.

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An updated review on ablative treatment of pancreatic cystic lesions
Andrew Canakis, Ryan Law, Todd Baron
Gastrointestinal Endoscopy.2020; 91(3): 520. CrossRef
Endosonography-guided Radiofrequency Ablation in Pancreatic Diseases
Giuseppe Vanella, Gabriele Capurso, Paolo G. Arcidiacono
Journal of Clinical Gastroenterology.2020; 54(7): 591. CrossRef

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Novel Therapeutic Strategies in the Management of Non-Variceal Upper Gastrointestinal Bleeding: Ari Garber, Sunguk Jang; Clin Endosc 2016;49(5):421-424. Published online September 30, 2016; DOI: https://doi.org/10.5946/ce.2016.110

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Non-variceal upper gastrointestinal bleeding, the most common etiology of which is peptic ulcer disease, remains a persistent challenge despite a reduction in both its incidence and mortality. Both pharmacologic and endoscopic techniques have been developed to achieve hemostasis, with varying degrees of success. Among the pharmacologic therapies, proton pump inhibitors remain the mainstay of treatment, as they reduce the risk of rebleeding and requirement for recurrent endoscopic evaluation. Tranexamic acid, a derivative of the amino acid lysine, is an antifibrinolytic agent whose role requires further investigation before application. Endoscopically delivered pharmacotherapy, including Hemospray (Cook Medical), EndoClot (EndoClot Plus Inc.), and Ankaferd Blood Stopper (Ankaferd Health Products), in addition to standard epinephrine, show promise in this regard, although their mechanisms of action require further investigation. Non-pharmacologic endoscopic techniques use one of the following two methods to achieve hemostasis: ablation or mechanical tamponade, which may involve using endoscopic clips, cautery, argon plasma coagulation, over-the-scope clipping devices, radiofrequency ablation, and cryotherapy. This review aimed to highlight these novel and fundamental hemostatic strategies and the research supporting their efficacy.

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Functional and structural neurodegenerative activities of Ankaferd BloodStopper in a mouse sciatic nerve model
Ramazan Üstün, Elif Oğuz, Ayşe Şeker, Filiz Taspinar
Experimental and Therapeutic Medicine.2024;[Epub] CrossRef
Hemostatic powder for acute upper gastrointestinal bleeding: Recent research advances
Dong-Shuai Su, Cheng-Kun Li, Cong Gao, Xing-Shun Qi
World Chinese Journal of Digestology.2023; 31(7): 249. CrossRef
Short Peptide Nanofiber Biomaterials Ameliorate Local Hemostatic Capacity of Surgical Materials and Intraoperative Hemostatic Applications in Clinics
Zehong Yang, Lihong Chen, Ji Liu, Hua Zhuang, Wei Lin, Changlong Li, Xiaojun Zhao
Advanced Materials.2023;[Epub] CrossRef
The Reduction of After-Hours and Weekend Effects in Upper Gastro-intestinal Bleeding Mortality During the COVID-19 Pandemic Compared to the Pre-Pandemic Period
Sergiu Marian Cazacu, Adina Turcu-Stiolica, Dan Nicolae Florescu, Bogdan Ungureanu, Vlad Florin Iovanescu, Carmen Daniela Neagoe, Daniela Burtea, Amelia Valentina Genunche-Dumitrescu, Taina Elena Avramescu, Sevastita Iordache
Journal of Multidisciplinary Healthcare.2023; Volume 16: 3151. CrossRef
Hemostatic efficacy and safety of the hemostatic powder UI-EWD in patients with lower gastrointestinal bleeding
Boram Cha, Donghyun Lee, Jongbeom Shin, Jin-Seok Park, Gye-suk Kwon, Hyungkil Kim
BMC Gastroenterology.2022;[Epub] CrossRef
The Haemostatic Effects of Ankaferd Blood Stopper® on Mammalian Brain Parenchyma: An Experimental Study
Emrah EGEMEN, Ümit Akın DERE, Başak ÜNVER KOLUMAN, Yücel DOĞRUEL, Ahmet KOLUMAN, Batuhan BAKIRARAR, Nazlı ÇİL, Esin AVCI, Emine TURAL, Fatih YAKAR
Batı Karadeniz Tıp Dergisi.2022; 6(1): 31. CrossRef
Method of diagnosis and treatment of profusional bleeding from stenosing postbulbar ulcers of the duodenum
Volodymyr Mamchych, Sergiy Vereshchagin, Volodymyr Maksymchuk, Dmytro Maksymchuk
EUREKA: Health Sciences.2021; (2): 37. CrossRef
Case Report: Peptic ulcer disease following short-term use of nonsteroidal anti-inflammatory drugs in a 3-year-old child
Alin Dumitru Ciubotaru, Carmen-Ecaterina Leferman
F1000Research.2021; 9: 419. CrossRef
Outcomes from an international multicenter registry of patients with acute gastrointestinal bleeding undergoing endoscopic treatment with Hemospray
Durayd Alzoubaidi, Mohamed Hussein, Radu Rusu, Duncan Napier, Selena Dixon, Johannes W. Rey, Cora Steinheber, Sina Jameie‐Oskooei, Martin Dahan, Bu Hayee, Shraddha Gulati, Edward Despott, Alberto Murino, Sharmila Subramaniam, Sulleman Moreea, Phil Boger,
Digestive Endoscopy.2020; 32(1): 96. CrossRef
Comprehensive Bioanalysis of Ultrahigh Molecular Weight, Highly Disperse Poly(ethylene oxide) in Rat via Microsolid Phase Extraction and RPLC-Q-Q-TOF Coupled with the MSALL Technique
Zhi Zhang, Hui Jiang, Yuyao Zhang, Di Zhang, John Paul Fawcett, Jingkai Gu
Analytical Chemistry.2020; 92(8): 5978. CrossRef
Case Report: Peptic ulcer disease following short-term use of nonsteroidal anti-inflammatory drugs in a 3-year-old child
Alin Dumitru Ciubotaru, Carmen-Ecaterina Leferman
F1000Research.2020; 9: 419. CrossRef
Helicobacter pylori–Negative MALT Lymphoma Presenting as a Massive Recurrent Gastrointestinal Hemorrhage
Prateek S. Harne, Samiran Mukherjee, Ted Achufusi, Dhruv Lowe, Divey Manocha
Journal of Investigative Medicine High Impact Case Reports.2020;[Epub] CrossRef
Management of non-variceal upper gastrointestinal bleeding: where are we in 2018?
Durayd Alzoubaidi, Laurence B Lovat, Rehan Haidry
Frontline Gastroenterology.2019; 10(1): 35. CrossRef
New endoscopic techniques in treating gastrointestinal bleeding
Young Sin Cho
International Journal of Gastrointestinal Intervention.2018; 7(3): 131. CrossRef
First-line endoscopic treatment with over-the-scope clips in patients with either upper or lower gastrointestinal bleeding: a multicenter study
Raffaele Manta, Santi Mangiafico, Angelo Zullo, Helga Bertani, Angelo Caruso, Giuseppe Grande, Francesco Paolo Zito, Benedetto Mangiavillano, Luigi Pasquale, Andrea Parodi, Bastianello Germanà, Gabrio Bassotti, Fabio Monica, Maurizio Zilli, Antonio Pisani
Endoscopy International Open.2018; 06(11): E1317. CrossRef
Hémorragies digestives : qui ? quand ? place des nouveaux traitements ?
D. Heresbach, A. Laquière
Acta Endoscopica.2017; 47(5): 281. CrossRef
Neuromuscular degenerative effects of Ankaferd Blood Stopper® in mouse sciatic nerve model
Ramazan Üstün, Elif Kaval Oğuz, Çağrı Delilbaşı, Ayşe Şeker, Filiz Taşpınar, Mehmet Reşit Öncü, Ahmet Regaip Oğuz
Somatosensory & Motor Research.2017; 34(4): 248. CrossRef
Pharmacologic Management of Nonvariceal Upper Gastrointestinal Bleeding
Jeong Hwan Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2016; 16(4): 189. CrossRef

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