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Endoscopic Features of Mucous Cap Polyps: A Way to Predict Serrated Polyps
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Brian T. Moy, Faripour Forouhar, Chia-Ling Kuo, Thomas J. Devers
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Clin Endosc 2018;51(4):368-374. Published online April 27, 2018
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DOI: https://doi.org/10.5946/ce.2017.155
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 Abstract
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- Background
/Aims: The aims of the study were to identify whether a mucous-cap predicts the presence of serrated polyps, and to determine whether additional endoscopic findings predict the presence of a sessile serrated adenomas/polyp (SSA/P).
Methods
We analyzed 147 mucous-capped polyps with corresponding histology, during 2011–2014. Eight endoscopic features (presence of borders, elevation, rim of debris, location in the colon, size ≥10 mm, varicose vessels, nodularity, and alteration in mucosal folds) of mucous-capped polyps were examined to see if they can predict SSA/Ps.
Results
A total of 86% (n=126) of mucous-capped polyps were from the right sided serrated pathway (right-sided hyperplastic [n=83], SSA/Ps [n=43], traditional serrated adenoma [n=1]), 10% (n=15) were left-sided hyperplastic polyps, and 3% (n=5) were from the adenoma-carcinoma sequence. The presence of a mucous cap combined with varicose vessels was the only significant predictor for SSA/Ps. The other seven characteristics were not found to be statistically significant for SSA/Ps, although location in the colon and the presence of nodularity trended towards significance.
Conclusions
Our study suggests that mucous-capped polyps have high predictability for being a part of the serrated pathway. Gastroenterologists should be alert for a mucous-capped polyp with varicose veins, as these lesions have a higher risk of SSA/P.
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Citations
Citations to this article as recorded by  - Clinicopathological features and expression of regulatory mechanism of the Wnt signaling pathway in colorectal sessile serrated adenomas/polyps with different syndrome types
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Annals of Clinical Microbiology and Antimicrobials.2020;[Epub] CrossRef - Endoscopic features of sessile serrated adenoma/polyps under narrowband imaging: A retrospective study
Xin Tian Zhang, Qing Wei Zhang, Fei Liu, Xiao Lu Lin, Jin Nan Chen, Xiao Bo Li
Journal of Digestive Diseases.2019; 20(3): 135. CrossRef - How to Detect Sessile Serrated Adenoma/Polyps
Eun Ran Kim, Dong Kyung Chang
Clinical Endoscopy.2018; 51(4): 313. CrossRef
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