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Erratum: United Rapid Urease Test Is Superior than Separate Test in Detecting Helicobacter pylori at the Gastric Antrum and Body Specimens
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Sung Woon Moon, Tae Hyo Kim, Hyeon Sik Kim, Ji-Hyeon Ju, Yeon Jeong Ahn, Hyun Jeong Jang, Sang Goon Shim, Hyun Jin Kim, Woon Tae Jung, Ok-Jae Lee
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Clin Endosc 2013;46(3):310-310. Published online May 31, 2013
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DOI: https://doi.org/10.5946/ce.2013.46.3.310
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 PDF PubReader ePub
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United Rapid Urease Test Is Superior than Separate Test in Detecting Helicobacter pylori at the Gastric Antrum and Body Specimens
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Sung Woon Moon, Tae Hyo Kim, Hyeon Sik Kim, Ji-Hyeon Ju, Yeon Jeong Ahn, Hyun Jeong Jang, Sang Goon Shim, Hyun Jin Kim, Woon Tae Jung, Ok-Jae Lee
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Clin Endosc 2012;45(4):392-396. Published online November 30, 2012
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DOI: https://doi.org/10.5946/ce.2012.45.4.392
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 Abstract
PDFPubReaderePub
- Background/Aims
The rapid urease test (RUT) is an invasive method to diagnose Helicobacter pylori infection, which relies on the acquisition and examination of gastric antrum and body tissues. We determined and compared the efficacy of RUT when the tissues were examined separately or after being combined. MethodsTwo hundred and fourteen patients were included and underwent esophagogastroduodenoscopy from July 2008 to June 2010. The separate test was defined as evaluating the status of infectivity of H. pylori from the antrum and body separately; whereas the united test was carried out putting both tissues from the antrum and body in the same RUT kit. All RUTs were read by a single observer 1, 3, 6, 12, and up to 24 hours later. We also got two biopsy specimens stained with hematoxylin and eosin and quantified H. pylori density was calculated on a scale of 0 to 3. ResultsOverall positivity for H. pylori was 137 (64%) for the separate test and 148 (69.2%) for the united test (p<0.01). The mean time to a positive test was 3.58 hours for the separate test and 1.69 hours for the united test (p<0.01). The correlation between the time to positive RUT and the severity of histology showed r=+0.556 for the antrum (p<0.01) and r=+0.622 for the body (p<0.01). ConclusionsCombining tissues prior to RUT enhances the detection of H. pylori, as compared with the examination of separate tissues, and shortens the time to develop a positive reaction by approximately 50%. These diagnostic advantages are also accompanied by increased cost-savings.
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