Xanthogranulomatous inflammation (XGI) is a rare benign inflammatory disease characterized by aggregation of lipid-laden foamy macrophages. This disease entity has been described in various organs but most commonly in the kidney and gallbladder. The occurrence of this disease in the lower gastrointestinal tract is extremely rare. Its clinical importance is that it can be misdiagnosed as an infiltrative cancer. In this case report, a 52-year-old male complained of right lower quadrant abdominal pain for a period of 3 months. Abdominal computed tomography revealed appendiceal mass and colonoscopy revealed multiple erythematous nodular lesions in the terminal ileum and appendiceal orifice, mimicking appendiceal cancer. Right hemicolectomy was done and the pathological specimen revealed XGI of the terminal ileum. To our knowledge, this is the first case of XGI in terminal ileum presenting as abdominal pain and the appendiceal mass on radiologic findings.

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• Imaging and Clinical Findings of Xanthogranulomatous Inflammatory Disease of Various Abdominal and Pelvic Organs: A Pictorial Essay
  Se Jin Lee, Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Kyu Yeoun Won, So Hyun Park, Woo Kyoung Jeong
  Journal of the Korean Society of Radiology.2024; 85(1): 109.     CrossRef
• Xanthogranulomatous inflammation and spindle cell proliferation in response to silicone breast implant leakage
  Kyra Ji-Young Lee, Jue Li Seah, Sandra O’Toole, Sanjay Warrier
  BMJ Case Reports.2023; 16(1): e252091.     CrossRef
• Xanthogranulomatous inflammation requiring small bowel anastomosis revision: A case report
  William Wang, Maria Korah, Kovi E Bessoff, Jeanne Shen, Joseph D Forrester
  World Journal of Gastrointestinal Surgery.2023; 15(3): 488.     CrossRef
• Xanthogranulomatous Oophoritis in the Setting of Post-IVF Twin Pregnancy with History of Endometriosis: A Rare Case Report with Review of Literature
  Chinmay Shrikrishna Pendharkar, Sunita B.S, Ganesh Pendkur, Dheeraj J. Nandagawe
  Indian Journal of Medical and Paediatric Oncology.2022; 43(03): 314.     CrossRef
• Xanthogranulomatous appendicitis diagnosed on routine PET scan: a case report
  Alexandra C Skoczek, Dennis L Fernandez
  Journal of Surgical Case Reports.2022;[Epub]     CrossRef
• A Case of Xanthogranulomatous Inflammation of Terminal Ileum Presenting as a Mass in a Woman with Severe Obesity
  Hyung Ku Chon, Sang Wook Kim
  The Korean Journal of Gastroenterology.2016; 67(5): 277.     CrossRef
• Abdominal manifestations of histiocytic disorders in adults: imaging perspective
  Abhijit Sunnapwar, Christine O Menias, Vijaynadh Ojili, Maria Policarpio Nicolas, Rashmi Katre, Kiran Gangadhar, Arpit Nagar
  The British Journal of Radiology.2016; 89(1065): 20160221.     CrossRef
• Small Bowel Obstruction due to Intestinal Xanthomatosis
  L. E. Barrera-Herrera, F. Arias, P. A. Rodríguez-Urrego, M. A. Palau-Lázaro
  Case Reports in Pathology.2015; 2015: 1.     CrossRef
• Positron Emission Tomography/Computed Tomography False Positivity for Xanthogranulomatous Inflammation in an Adolescent with Hodgkin's Lymphoma
  Jui-Ting Yu, Chieh-Lin Jerry Teng, Ying-Chu Lin, Ren-Ching Wang, Wen-Li Hwang
  Journal of Cancer Research and Practice.2014; 1(1): 50.     CrossRef
• Xanthogranulomatous capsulitis mimicking a polypoid neoplasm disease: an unusual presentation of ruptured Poly Implant Prothèse (PIP) breast implant
  Fernando Hernanz, Sara Baeza, Eduardo Serna, Manuel Gómez-Fleitas
  European Journal of Plastic Surgery.2013; 36(12): 797.     CrossRef