Clinical Endoscopy

Young Chul Choi

2 Articles

Peroral Endoscopic Myotomy for Treating Achalasia in an Animal Model: A Feasibility Study: Byoung Wook Bang, Young Chul Choi, Hyung Gil Kim, Kye Sook Kwon, Yong Woon Shin, Don Haeng Lee, Joon Mee Kim; Clin Endosc 2013;46(1):54-58. Published online January 31, 2013; DOI: https://doi.org/10.5946/ce.2013.46.1.54

Background/Aims

Laparoscopic Heller myotomy with antireflux procedure is considered to be a standard treatment for achalasia. Recently, peroral endoscopic myotomy (POEM) was developed and performed on patients with achalasia. However, there is no report on POEM use in South Korea. The aim of this study was to evaluate the technical feasibility of POEM in a porcine model.

Methods

POEM was performed on two mini pigs. We performed upper endoscopy under general anesthesia. A submucosal tunnel was created and the circular muscle layer was incised using several knives. The mucosal entry was closed using resolution clips. We performed a follow-up endoscopy and sacrificed the pigs 2 weeks after the POEM. The myotomy site was evaluated grossly and histologically.

Results

POEM was successfully performed on the two mini pigs. No injuries to any abdominal or mediastinal structures occurred. Two weeks after the POEM, the esophageal mucosa healed without any endoscopic evidence of complications. Necropsy revealed that the circular muscle layer was completely lost and replaced with fibrotic tissue.

Conclusions

We found that POEM is a technically feasible method which can be performed on an animal model. However, to ensure safe use on patients with achalasia, further studies on technical methods and long-term follow-up examinations are required.

Citations

Citations to this article as recorded by

Pilot prospective study on formal training in per-oral endoscopic myotomy (POEM) during advanced endoscopy fellowship
Salmaan Jawaid, Peter V. Draganov, Hiroyuki Aihara, Mouen A. Khashab, Dennis Yang
Endoscopy International Open.2021; 09(12): E1890. CrossRef
Miotomía endoscópica peroral, experiencia in vivo : imprescindible para desarrollo de la técnica en humanos
A. Peñaloza-Ramírez, J. Suárez-Correa, J. Báez-Blanco, C. Sabogal-Gómez, H. Kuan-Casas, C. Sánchez-Pignalosa, P. Aponte-Ordóñez
Revista de Gastroenterología de México.2018; 83(2): 86. CrossRef
In vivo experience with peroral endoscopic myotomy: An essential activity for developing the technique in humans
A. Peñaloza-Ramírez, J. Suárez-Correa, J. Báez-Blanco, C. Sabogal-Gómez, H. Kuan-Casas, C. Sánchez-Pignalosa, P. Aponte-Ordóñez
Revista de Gastroenterología de México (English Edition).2018; 83(2): 86. CrossRef
Factors predicting the technical difficulty of peroral endoscopic myotomy for achalasia
Xiaowei Tang, Yutang Ren, Zhengjie Wei, Jieqiong Zhou, Zhiliang Deng, Zhenyu Chen, Bo Jiang, Wei Gong
Surgical Endoscopy.2016; 30(9): 3774. CrossRef
Peroral endoscopic myotomy for treatment of achalasia in children and adolescents
Chenjie Li, Yuyong Tan, Xuehong Wang, Deliang Liu
Journal of Pediatric Surgery.2015; 50(1): 201. CrossRef
The Ideal Experimental Training Session for Minimally Invasive Endoluminal Techniques
Sakai P
Gastroenterology & Hepatology: Open Access.2015;[Epub] CrossRef
International Digestive Endoscopy Network 2014: Turnpike to the Future
Eun Young Kim, Kwang An Kwon, Il Ju Choi, Ji Kon Ryu, Ki Baik Hahm
Clinical Endoscopy.2014; 47(5): 371. CrossRef
Training for peroral endoscopic myotomy
Daniel von Renteln, Melina C. Vassiliou, Thomas Rösch
Techniques in Gastrointestinal Endoscopy.2013; 15(3): 153. CrossRef
Peroral Endoscopic Myotomy for the Treatment of Achalasia: An Analysis
Dennis Yang, Mihir S. Wagh
Diagnostic and Therapeutic Endoscopy.2013; 2013: 1. CrossRef
Peroral Endoscopic Myotomy in a Porcine Model: A Step to Achalasia Patients
Su Jin Hong
Clinical Endoscopy.2013; 46(1): 1. CrossRef

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Two Cases of Ileal Dieulafoy Lesion with Massive Hematochezia Treated by Single Balloon Enteroscopy: Young Chul Choi, Sang Hyun Park, Byoung Wook Bang, Kye Sook Kwon, Hyung Gil Kim, Yong Woon Shin; Clin Endosc 2012;45(4):440-443. Published online November 30, 2012; DOI: https://doi.org/10.5946/ce.2012.45.4.440

Abstract PDF PubReader ePub

Ileal Dieulafoy lesion is an unusual vascular abnormality that can cause gastrointestinal bleeding. It can be associated with massive, life-threatening hemorrhage and requires urgent angiographic intervention or surgery. Ileal Dieulafoy lesion is hard to recognize due to inaccessibility and normal-appearing mucosa. With advances in endoscopy, aggressive diagnostic and therapeutic approaches including enteroscopy have recently been performed for small bowel bleeding. We report two cases of massive ileal Dieulafoy lesion bleeding diagnosed and treated successfully by single balloon enteroscopy with a review of the literature.

Citations

Citations to this article as recorded by

A diagnostic dilemma: a case report of concomitant duodenal Dieulafoy lesion and gastric ulcer
Lauren Wallace, Peter J Gallagher
Journal of Surgical Case Reports.2024;[Epub] CrossRef
Stitch in time saves nine
Aisha Rummaan, Irene Lee, Deepa Rattehalli, Prajesh Kumar, Sauid Ishaq
Frontline Gastroenterology.2023; 14(3): 265. CrossRef
Ileal Dieulafoy Lesion: a rare case report
Aleena Jain, Manjusha Karegar, Amita Joshi, Amey Rojekar
Surgical and Experimental Pathology.2018;[Epub] CrossRef
The Role of Emergency Endoscopy in Small Bowel Bleeding: A Review
Enrique Pérez-Cuadrado-Robles, Enrique Pérez-Cuadrado-Martínez
GE Portuguese Journal of Gastroenterology.2016; 23(2): 84. CrossRef
An Unusual Cause of Torrential Lower Gastrointestinal Hemorrhage
Terence C. Chua, Anthony J. Gill, Jaswinder S. Samra
Gastroenterology.2015; 148(5): e10. CrossRef

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