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Underestimation of endoscopic size in large gastric epithelial neoplasms
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Jae Sun Song, Byung Sun Kim, Min A Yang, Young Jae Lee, Gum Mo Jung, Ji Woong Kim, Jin Woong Cho
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Clin Endosc 2022;55(6):760-766. Published online May 19, 2022
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DOI: https://doi.org/10.5946/ce.2021.269
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Abstract
PDFPubReaderePub
- Background
/Aims: Endoscopic submucosal dissection (ESD) is an effective method for resecting gastric adenomas and adenocarcinomas. A significant discrepancy was observed between endoscopic and pathological sizes in samples obtained from patients undergoing ESD. This study elucidates the factors affecting size discrepancy after formalin fixation.
Methods The records of 64 patients with 69 lesions were analyzed, including 50 adenomas and 19 adenocarcinomas. Data on location, gross shape, histology, and size after fixation in formalin were collected.
Results The mean size of the resected specimen appeared to decrease after formalin fixation (37.5 mm prefixation vs. 35.8 mm postfixation, p<0.05). The mean long axis diameter of the lesions was 20.3±7.9 mm prefixation and 13.4±7.9 mm postfixation. Size differences in lesions smaller than 20 mm were significantly greater than those in lesions larger than 20 mm (7.6±5.6 mm vs. 2.5±5.8 mm, p<0.01). In multivariate analysis, a tumor size of ≥20 mm was found to be an independent factor affecting size postformalin fixation (p<0.05).
Conclusions The endoscopic size of lesions before ESD may be underestimated in tumors larger than 20 mm in size. Therefore, increased attention must be paid during ESD to avoid instances of incomplete resection.
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- Transcecal endoscopic appendectomy for management of complex appendiceal polyps extending into the appendiceal orifice
Tara Keihanian, Mai A Khalaf, Fuad Zain Aloor, Dina Hani Zamil, Salmaan Jawaid, Mohamed O. Othman Endoscopy International Open.2024; 12(08): E932. CrossRef
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An Intractable Caustic Esophageal Stricture Successfully Managed with Sequential Treatment Comprising Incision with an Insulated-Tip Knife, Balloon Dilation, and an Oral Steroid
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Woong Ki Lee, Byung Sun Kim, Min A Yang, So Hee Yun, Young Jae Lee, Ji Woong Kim, Jin Woong Cho
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Clin Endosc 2016;49(6):560-563. Published online August 12, 2016
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DOI: https://doi.org/10.5946/ce.2016.048
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Abstract
PDFPubReaderePub
- Bougie or balloon dilation is a good short-term treatment for caustic esophageal strictures, although recurrence after dilation occurs in approximately 30% of these cases. Therefore, long-term treatment options are required in some cases, and endoscopic incisional therapy has been used for patients with an anastomotic stricture in the gastrointestinal tract. A 58-year-old woman presented with severe swallowing difficulty because of a caustic esophageal stricture, which was caused by accidental exposure to anhydrous acetic acid at infancy. She had undergone several previous bougie and balloon dilations but the stricture did not improve. We performed sequential treatment comprising incision with an insulated-tip knife, balloon dilation, and an oral steroid, which resulted in the patient’s symptoms markedly improving. Thus, we report this case of an intractable caustic esophageal stricture, which was successfully treated using combined endoscopic sequential treatment.
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Citations
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- A new simple endoscopic incision therapy for refractory benign oesophageal anastomotic stricture
Jeongmin Choi, Soo In Choi BMJ Case Reports.2021; 14(3): e239798. CrossRef - Endoscopic incision for treatment of benign gastrointestinal strictures
Chengbai Liang, Yuyong Tan, Jiaxi Lu, Meixian Le, Deliang Liu Expert Review of Gastroenterology & Hepatology.2020; 14(6): 445. CrossRef
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Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and a Literature Review of 13 Cronkhite-Canada Syndrome Cases in Korea
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So Hee Yun, Jin Woong Cho, Ji Woong Kim, Joong Keun Kim, Moon Sik Park, Na Eun Lee, Jae Un Lee, Young Jae Lee
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Clin Endosc 2013;46(3):301-305. Published online May 31, 2013
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DOI: https://doi.org/10.5946/ce.2013.46.3.301
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Abstract
PDFPubReaderePub
Cronkhite-Canada syndrome (CCS) is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances both in the gastrointestinal tract and in the epidermis. The pathologic finding of the polyp is usually a hamartomatous polyp of the juvenile type; however, the possibility of serrated adenoma associated malignant neoplasm was reported in some Japanese cases. Up till now in South Korea, 13 CCS cases have been reported, but there was no case accompanied by the colon cancer. We report the first case of CCS associated with malignant colon polyp and serrated adenoma in Korea. A 72-year-old male patient who complained of diarrhea and weight loss was presented with both hands and feet nail dystrophy, hyperpigmentation, and alopecia. Endoscopic examination showed numerous hamartomatous polyps from the stomach to the colon. The pathologic results confirmed colon cancer and serrated adenoma. Helicobacter pylori eradication and prednisolone was used. Thus, the authors report this case along with a literature review.
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Citations
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- Differential Diagnoses and Management Approaches for Gastric Polyposis
Masaya Iwamuro, Seiji Kawano, Motoyuki Otsuka Gastroenterology Insights.2024; 15(1): 122. CrossRef - Cronkhite-Canada Syndrome Presenting with life-threatening protein-losing enteropathy: a case report
Tolga Olmez Medical Science Pulse.2023; 16(4): 1. CrossRef - Estimated Prevalence of Cronkhite-Canada Syndrome, Chronic Enteropathy Associated With SLCO2A1 Gene, and Intestinal Behçet’s Disease in Japan in 2017: A Nationwide Survey
Mari S. Oba, Yoshitaka Murakami, Yuji Nishiwaki, Keiko Asakura, Satoko Ohfuji, Wakaba Fukushima, Yosikazu Nakamura, Yasuo Suzuki Journal of Epidemiology.2021; 31(2): 139. CrossRef - Gewichtsverlust, Diarrhöen und dystrophe Veränderungen der Fingernägel bei einem 80-jährigen Patienten
Manuel Strohmeier Der Internist.2021; 62(1): 100. CrossRef - Successful surgical treatment of Cronkhite-Canada Syndrome with bilateral flail chest: a case report
Guang-chao Lv, Zhi-hong Li, Zong-sheng Duan, Chun-bo Niu, Ming-he Li, Kai-zhong Wang, Jin-dong Jiang BMC Surgery.2020;[Epub] CrossRef - Cronkhite–Canada syndrome: from clinical features to treatment
Ze-Yu Wu, Li-Xuan Sang, Bing Chang Gastroenterology Report.2020; 8(5): 333. CrossRef - Case of Cronkhite Canada Syndrome - A Non-Inherited Gastrointestinal Polyposis Syndrome
Arun Solanki, Rajesh Bhurkunde Journal of Evolution of Medical and Dental Sciences.2019; 8(40): 3046. CrossRef - Cronkhite-Canada Syndrome Showing Good Early Response to Steroid Treatment
Woohee Cho, Kwangwoo Nam, Ki Bae Bang, Hyun Deok Shin, Jeong Eun Shin The Korean Journal of Gastroenterology.2018; 71(4): 239. CrossRef - Cronkhite-Canada Syndrome Associated with Metastatic Colon Cancer
Shirin Haghighi, Sima Noorali, Amir Houshang Mohammad Alizadeh Case Reports in Gastroenterology.2018; 12(1): 109. CrossRef - Compound traditional serrated adenoma and sessile serrated adenoma
Carlos A Rubio, Åsa Edvardsson, Jan Björk, Anne Tuomisto, Timo Väisänen, Markus Mäkinen Journal of Clinical Pathology.2016; 69(8): 745. CrossRef - Cronkhite-Canada Syndrome: an unusual finding of gastro-intestinal adenomatous polyps in a syndrome characterized by hamartomatous polyps
Christopher M. Flannery, John A. Lunn Gastroenterology Report.2015; 3(3): 254. CrossRef - Cases Report the Cronkhite-Canada Syndrome
Yi Qun Yu, Peter James Whorwell, Lin Heng Wang, Jun Xiang Li, Qing Chang, Jie Meng Medicine.2015; 94(52): e2356. CrossRef - Cronkhite–Canada syndrome six decades on: the many faces of an enigmatic disease
Tomas Slavik, Elizabeth Anne Montgomery Journal of Clinical Pathology.2014; 67(10): 891. CrossRef - A Case of Cronkhite-Canada Syndrome Showing Spontaneous Remission
Dong-Uk Kang, Dong-Hoon Yang, Yunsik Choi, Ji-Beom Kim, Ho-Su Lee, Hyo Jeong Lee, Sang Hyoung Park, Kee Wook Jung, Kyung-Jo Kim, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Jin-Ho Kim Intestinal Research.2013; 11(4): 317. CrossRef
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