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Volume 21(5); November 2000
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소화기 내시경에 대한 Superoxidized Water ( Cleantop )의 소독 효과 ( The Value of Superoxidized Water ( Claentop ) for Endoscopic Disinfection )
Korean J Gastrointest Endosc 2000;21(5):819-824.   Published online November 30, 1999
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Background
/Aims: Conventional disinfectants are expensive, hazardous, and often require long periods of exposure. The aim of this study was to evaluate the effectiveness of a new endoscopic disinfector (Cleantop) that uses superoxidized water (SW) as a disinfectant. Methods: Immediately after patient examinations endoscopes were cleaned manually and disinfected with SW for seven minutes. Cultures were taken from valves (swabbing), biopsy channels (rinsing), and biopsy channels after brushing (rinsing). The results were compared with those of other disinfectants tested previously by the same culture methods. Results: Of 12 endoscopes disinfected with SW, disinfection rates were 83.3%, 58.3% and 25% at valves, channels and channels after brushing, respectively. In no instances were more than 100 colony forming units (cfu) of bacteria recovered from each endoscope. SW was similar to peroxygen compound (33.3%, 50%, 50%) and 2% glutaraldehyde (100%, 16.7%, 16.7%) in its disinfectant effect, since 100 or more cfu of bacteria were recovered only from endoscopes disinfected with peroxygen compound. The number of bacterial recovered from endoscopes disinfected with 2% glutaraldehyde was less than 10 cfu. Conclusions: Disinfection with SW appears to be an effective and time-saving alternative to conventional disinfectants.
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위 정맥류출혈에 대한 내시경적 결찰요법과 Histoacryl 치료 효과의 비교 ( The Comparative Study of Ligation and Histoacryl Injection in Gastric Varix Bleeding )
Korean J Gastrointest Endosc 2000;21(5):825-831.   Published online November 30, 1999
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Background
/Aims: The variceal bleeding has high rebleeding rate, and mortality rate was higher in gastrix varix. Managements of variceal bleeding were included such as drugs, endoscopic procedures, surgical management and radiological intervention. Recently histoacryl injection method has been introduced. We have compared the effects of the endoscopic ligation and Histoacryl injection therapy (HAI) in patient with gastric variceal bleeding. Methods: We analyzed the effects of hemostasis, complications, rebleeding rates, and survival rates in gastric varix bleeding of 22 patients with Histoacryl injection therapy and 20 patients with endoscopic ligation therapy, from January 1995 to March 1999. Results: There were no difference in the complication rate between the 2 stretigies (12/14). Most common complication was chest pain in EVL group, but fever was common in HAI group. Also early and post rebleeding rates were not different in both groups. The main cause of death during follow up period was rebleeding in both groups. The survival rates were 65.0% in EVL group and 77.0% in HAI group (p>0.05, duration: 23±2, 28±4 month), and there was no difference in mortlity rate (p=0.77). Conclusions: There were no difference in the hemostatic effect, complications, rebleeding rate and survival rate in EVL group and HAI group. However, evaluation of larger numbers of patients and prospective studies were needed to define the effectiveness and complications of these therapies.
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Helicobacter pylori 제균치료에 Rebamipide ( Mucosta ) 의 유용성 ( Effect of Rebamipide ( Mucosta ) in Eradication of Helicobacter pylori )
Korean J Gastrointest Endosc 2000;21(5):832-837.   Published online November 30, 1999
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Bakground/Aims: Eradication of Helicobacter pylori infection is highly efficacious in preventing the recurrence of peptic ulcer. Rebamipide (Mucosta) is known to have the ability to inhibit neutrophil activity, to reduce the production of inflammatory cytokines, to scavenge oxygen radical, and to stimulate prostaglandin production. This study was designed to evaluate the effect of rebamipide on the eradication of H. pylori, and decrease of the infilatration of inflammatory cells. Methods: Eighty two patients with gastric or duodenal ulcers with H. pylori infection were allocated to two treatment groups. The patients were treated either with omeprazole 40 mg, clarithromycin 1.0 g, amoxicillin 2.0 g, rebamipide 300 mg (OCAR group) or omeprazole 40 mg, clarithromycin 1.0 g, amoxicillin 2.0 g (OCA group) for two weeks. Results: H. pylori was eradicated 56 out of 62 patients (90%) in OCAR group and 16 out of 20 patients (80%) in OCA group. The infiltration of inflammatory cells decreased in both treatment groups. No significant side effects had been noticed. Conclusions: The results of the present study suggest that rebamipide may be useful to decrease gastric mucosal inflammation in peptic ulcer disease. However, further detailed study will be reqiured to determine the potentially beneficial effect whether rebamipide can prevent the recurrence of peptic ulcer diseases with H. pylori infection.
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십이지장 궤양에 의한 유문 협착에서 풍선 확장술의 장기 효과 ( Long-Term Outcome of Endoscopic Balloon Dilatation of Benign Pyloric Stricture )
Korean J Gastrointest Endosc 2000;21(5):838-843.   Published online November 30, 1999
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Background
/Aims: Balloon dilatation is a useful alternative to surgery in patients with benign pyloric stenosis. However, little data are available on the long-term outcome of the procedure. This report was attempted to determine the safety and efficacy of endoscopic balloon dilatation for 14 patients with gastric outlet obstruction caused by duodenal ulcer. Methods: Review of medical records or telephone interview was performed retrospectively. Results: Follow-up was conducted for median 18.5 months (3-48 months). Gastric outlet strictures had a median diameter 6 mm (range, 2-9 mm). Five (35.7%) patients had active ulcer. 12 mm to 18 mm balloons were inflated a median of 1 times (range, 1-4 times) for a median of 4 minutes (range, 1 11 minutes). Thirty-two procedure (1.5/patient) were performed; 9 patients (64.3%) had one treatment and 5 patients (35.7%) had multiple treatment. Immediate symptomatic relief was achieved in 13 patients (92.8%) and 7 patients (50%) achieved sustained symptomatic relief. Dilatation failed only in 2 patients (14.3%) ultimately and both recovered by palliative bypass surgery. No complication was noted during treatment. Conclusions: Endoscopic balloon dilatation is safe and effective for most patients with gastric outlet obstruction induced by duodenal ulcer. And due to limitation of retrospective aspect of this report, further prospective, randomized studies must be performed.
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시사프라이드의 대장내시경 전처치 용액의 감량 효과 ( The Effects of Cisapride on Volume of Colonoscopy Lavage Solution )
Korean J Gastrointest Endosc 2000;21(5):844-848.   Published online November 30, 1999
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Background
/Aims: Polyethylene glycol (PEG) electrolyte lavage solution is now commonly used for peroral colonic preparation. However, the need to ingest a large volume reduces patient acceptance and may limit compliance, thereby resulting in improper preparation. This study was designed to assess whether adding of magnesium oxide or cisapride to PEG solution decreased the volume of PEG solution required without compromising the quality of the preparation. Methods: One hundred thirty seven patients undergoing outpatient colonoscopy were randomly chosen to receive one of three preparations (Group A: 4 L PEG; Group B: 2 L PEG plus cisapride 20 mg; Group C: 2 L PEG plus magnesium oxide 2 g). Endoscopist was blinded as to the method of preparation and scored the degree of colonic preparation (1 to 4). Results: Mean scores of preparation in group A, B, and C were 2.85, 2.69, and 2.20, respectively (p=0.001). There were significant differences of the degree of preparation between group A and group C, between group B and group C, but not between group A and group B. Conclusions: Two liters of PEG plus cisapride induced equally effective colonic preparation compared to four liter PEG solution. This results show that the addition of cisapride to PEG solution can reduce volume of PEG solution during colonoscopy preparation.
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융기형 조기 대장암의 육안적 분류와 조직병리학적 고찰 ( Macroscopic Classification and Histo-Pathologic Evaluation of Early Colorectal Cancer with Elevated Type )
Korean J Gastrointest Endosc 2000;21(5):849-854.   Published online November 30, 1999
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Background
s/Aims: Early colorectal cancer is defined as carcinoma with invasion to mucosa or submucosa irrespective of involvement of lymph node. Gross morphology is divided into elevated and depressed type according to growth pattern. Until now, carcinomas with elevated type have been found more frequently than depressed type in Korea. It is necessary to classify the macroscopy of morphology and evaluate histo-pathologic findings of early colorectal cancers. Methods: 33 patients (35 foci) with early colorectal cancers were analyzed, macroscopically and pathologically. Early colorectal carcinoma with mucosal invasion is 25 cases, and with submucosal invasion, 10. Results: Macroscopic classification; Ip 12, Isp 6, Is 9, IIa 1, IIa+IIc 4, Isp+IIc1, LST 2. Among them, Ip (34%) is most. Among cancers with mucosal invasion, Ip (36%) is common, and with submucosal invasion, Is (40%) is common. Most of early colorectal cancers with elevated type were accompanied with surrounding adenoma. It's ratio is 100% in early colorectal cancer with mucosal invasion, and 50% with submucosal invasion. Conclusions: Pedunculated type (Ip) is common in early colorectal cancer with elevated type. Surrounding adenoma was usually (85%) accompanied with those. It is suggestl that early colorectal cancer with elevated type would be originated from adenoma.
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위에 발생한 사구종양 1 예 : 내시경 초음파검사 소견을 중심으로 ( A Case of Glomus Tumor of the Stomach : Role of Endoscopic Ultrasonography )
Korean J Gastrointest Endosc 2000;21(5):855-858.   Published online November 30, 1999
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A glomus tumor of the stomach is a rare submucosal lesion that was first described by De Busscher in 1948. Submucosal tumors of the stomach are mostly leiomyoma, leiomyosarcoma, and malignant lymphoma. It is difficult to diagnose this kind of tumor preoperatively, We present a patient with a gastric glomus tumor which showed the characteristic endoscopic ultrasonographic (EUS) finding. Our case was also diagnosed by pathology after surgery. The major EUS findings in the present case are circumscribed low echoic mass in the forth submucosal layer and an internal heterogenous echo mixed with high echoic spots. The EUS seems to be useful in distinguishing between glomus tumor and other submucosal tumors.
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복부 둔상에 의한 위점막 열상 4 예 ( Four Cases of Gastric Mucosal Tear after Blunt Abdominal Trauma )
Korean J Gastrointest Endosc 2000;21(5):859-863.   Published online November 30, 1999
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The incidence of abdominal trauma has increased in recent decades as the frequency of traffic accidents increased. Early symptoms and signs of blunt abdominal trauma may be absent and associated injuries frequently detract physicians from early diagnosis of abdominal trauma. Delayed diagnosis has been shown to be associated with higher morbidity and mortality. Gastrointestinal tract is the third most commonly injured organ from blunt abdominal trauma. Gastric ruptures after blunt abdominal trauma were reported occasionally, but reports of upper gastrointestinal bleeding by gastric mucosal tear were very rare. Four cases of upper gastrointestinal bleeding due to gastric mucosal tear after blunt abdominal trauma are herein reported with a review of related literatures.
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선종과 동반된 위의 유암종 3 예 ( Three Cases of the Gastric Carcinoid Tumor Combined with the Gastric Adenoma )
Korean J Gastrointest Endosc 2000;21(5):864-868.   Published online November 30, 1999
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Carcinoid tumor in the stomach is neuroendocrine tumor originated from enterochromaffin cells in submucosa in the stomach. It is very rare, account for 0.3% of gastric tumor. It is likely to be demonstrated with other tumor in the stomach simultaneously, such as adenocarcinoma. According to paper published in Korea, it is only 4 cases that gastric carcinoid combined with other gastric tumors have been reported. But there has been no reports of gastric carcinoid combined with gastric adenoma, such as our cases. We report 3 cases of gastric carcinoid tumor combined with atypical adenoma, with review of paper presented.
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대장선암종에 수반된 폐쇄성 대장염 1 예 ( Obstructive Colitis Occuring Proximal to Colon Cancer )
Korean J Gastrointest Endosc 2000;21(5):869-872.   Published online November 30, 1999
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Obstructive colitis is an ulceroinflammatory lesion occurring proximal to an obstructing lesion in the colon. It is the result of ischemia due to impairment of blood supply secondary to elevation of the intraluminal pressure and other factors which impair adequate perfusion. The incidence among patients with colonic obstruction is reported to be between 1 and 7%. The patients are predominantly female and usually have hypertension, diabetes, or other prior chronic disease. Obstruction is occurred most commonly in the rectosigmoid area. In half of the patients, this is caused by adenocarcinoma. There is always an abrupt transitional zone between affected and normal bowel. A segment of preserved mucosa is usually presented on the proximal side of the stenosis. Areas of colitis occurs either as circumscribed ulcers or confluent circumferential lesions. They can occur as early mucosal hemorrhage and edema, and transmural necrosis. Microscopically, lesions are composed of granulation tissue with mixed acute and chronic inflammatory cells that replace the mucosa and often the submucosa. We report a case of obstructive colitis occuring proximal to colon cancer with a brief review of relevant literature.
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방사선 직장염과 동반된 직장선암 1 예 ( A Case of Rectal Adenocarcinoma with Radiation Colitis )
Korean J Gastrointest Endosc 2000;21(5):873-876.   Published online November 30, 1999
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Radiotherapy induced colorectal adenocarcinoma with radiation colitis after radiotherapy has been reported as a rare case. A patient with rectal adenocarcinoma as a late complication of pelvic irradiation for gynecological malignancy is reported. A 55-year-old woman with bloody diarrhea for 6 months was admitted. She received radiation therapy for carcinoma of cervix 21 years ago. Colonoscopic findings revealed a polypoid mass on rectosigmoid colon. Histopathologic examination of the polypectomy specimen disclosed adenocarcinoma. We reported herein a case of rectal adenocarcinoma with radiation colitis. The patient who had received pelvic irradiation should have close follow-up with colonoscopic study for the early detection of colorectal cancer.
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위암과 병발한 췌장의 Intraductal Papillary Mucinous Tumor 1 예 ( A Case of Intraductal Papillary Mucinous Tumor of the Pancreas Accompanied by Gastric Cancer )
Korean J Gastrointest Endosc 2000;21(5):877-881.   Published online November 30, 1999
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Intraductal papillary mucinous tumor (IPMT) of the pancreas is a distinct entity characterized by intraductal papillary growth and thick mucin secretion. Prolonged postoperative survival can be anticipated in many IPMT cases. However, IPMT of the pancreas was reported to be associated with a high incidence of nonpancreatic neoplasms and these nonpancreatic neoplasms have potential prognostic significance in patients with IPMT. Recently, we experienced a case of IPMT of the pancreas accompanied by gastric cancer in a 72-year-old woman. The main pancreatic duct was incidentally found to be dilated on an abdominal computed tomography performed for staging of gastric cancer. A subtotal gastrectomy and near-total pancreatectomy were carried out. Histopathologic examinations of the resected specimens confirmed the diagnosis of early gastric cancer (T₁N₁Mо) and IPMT of the pancreas, carcinoma in situ, combined type. We report this interesting case with a review of the literature.
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췌장의 Intraductal Papillary Mucinous Tumor ( IPMT ) 와 동반된 간내 점액 과분비 담관종양 ( A Case of Mucin-Hypersecreting Intrahepatic Bile Duct Tumor Combined with Pancreatic Intraductal Papillary Mucinous Tumor ( IPMT ) )
Korean J Gastrointest Endosc 2000;21(5):882-886.   Published online November 30, 1999
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Intraductal papillary mucinous tumor (IPMT) of the pancreas is a recently understood unique clinicopathologic disease entity comprising approximately 1% of all exocrine pancreatic tumors and 1l% of cysticneoplasms of pancreas. It has been reported worldwide, mostly in Japan. It is generally characterized by recurrent pancreatitis, mucin oozing from the papilla of Vater, and dilated pancreatic duct with intraductal filling defects. Microscopically, the mucin-producing columnar epithelium forms papillary proliferation into the dilated pancreatic duct and this feature differentiates IPMT of the pancreas from the more common mucinous cystic neoplasms of the pancreas which usually do not communicate with the pancreatic duct. On the other hand, mucin-hypersecreting bile duct tumors have been rarely reported in the English literature. We herein present the first case of mucin-hypersecreting bile duct tumor combied with IPMT of the pancreas with a review of the related literature.
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단신 : 악성 담괸 폐쇄에서 강낸 방사선 치료로 생존기간에 의미있는 영향을 줄 수 있는가?
Korean J Gastrointest Endosc 2000;21(5):887-888.   Published online November 30, 1999
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단신 : (답변) 악성 담괸 폐쇄에서 강낸 방사선 치료로 생존기간에 의미있는 영향을 줄 수 있는가?
Korean J Gastrointest Endosc 2000;21(5):888-889.   Published online November 30, 1999
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