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Volume 38(2); February 2009
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The Current Status and the Future of Upper GI Stenting
Jong-Jae Park, M.D. and Chang-Hun Yang, M.D., Ph.D.*
Korean J Gastrointest Endosc 2009;38(2):61-67.   Published online February 27, 2009
AbstractAbstract PDF
Stent implantation in the upper gastrointestinal (UGI) tract is now widely accepted for achieving palliative symptom relief of patients who have malignant UGI obstruction and causative symptoms such as nausea, vomiting, malnutrition and acid reflux. With the increased technical progress and clinical experiences, it has become possible to perform this procedure with more safety and convenience. However, clinicians should also focus on the post-procedural management because complications such as stent migration or in-stent tumor growth could occur. On the other hand, temporary stent insertion is an effective treatment option for benign diseases such as pyloric strictures due to benign peptic ulcer, esophageal perforation or leakage on the anastomosis site. In this review, several issues about stent implantation in the UGI tract, such as the main indications, the current status and the expected applications in other fields in the near future, are briefly discussed. (Korean J Gastrointest Endosc 2009;38:61-67)
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The Clinical Characteristics and Outcomes of Barrett's Cancer at a Single Institution in Korea
Sang-Jung Kim, M.D., Jun Haeng Lee, M.D., Beom Jin Kim, M.D., Poong-Lyul Rhee, M.D., Jae J. Kim, M.D., Jong Chul Rhee, M.D., Kyoung Mee Kim, M.D.* and Yong Mog Shim, M.D.
Korean J Gastrointest Endosc 2009;38(2):68-74.   Published online February 27, 2009
AbstractAbstract PDF

Background/Aims: The prevalence of Barrett's esophagus might also be changing along with changes in the epidemiology of GERD, and the incidence of Barrett's cancer is expected to increase even more. The aim of this study is to evaluate the clinicopathologic features and outcome of the patients with Barrett's cancer and who were seen at a single institution over a period of 13 years.

Methods: The records of 39 patients with the esophageal adenocarcinoma and who were treated at Samsung Medical Center from January 1995 to August 2008 were reviewed. Among them, 11 patients (28%) with histologically-confirmed Barrett's cancer were included in the study. The clinicopathological features, endoscopic manifestations and treatment outcome were evaluated.

Results: The male to female ratio was 10:1. The mean age was 64 years. Most of the patients were diagnosed with Barrett's cancer after 2000, and there were three such patients (27.3%) in 2008. The frequent chief complaints were epigastric pain (27.3%) and chronic acid reflux symptom (18.2%). Three patients (27.3%) were detected incidentally during screening endoscopy. The macroscopic types based on the endoscopic findings were as follows: 4 lesions with a type IIa appearance (36.4%) and 2 with a type IIb appearance (18.2%). The mean tumor size was 1.2 cm at the longest dimension and 0.8 cm at the shortest dimension. Tumor was located in the mucosal layer in six cases (54.5%) and the 5 cases (45.5%) showed submucosal invasion. Lymph node metastasis was found in one case (9.1%). All the cases underwent surgery, except one case for which the tumor was removed by endoscopic submucosal dissection. There was no recurrence during the follow up period.

Conclusions: As the incidence of Barrett's cancer is increasing, a standard surveillance program that includes the endoscopic biopsy method, the grading system for the dysplasia and the treatment modality should be established. (Korean J Gastrointest Endosc 2009;38:68-74)

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The Colonoscopic Withdrawal Time is Correlated with the Rate of Detecting Polyps When Performing Colonoscopy
Sang Bong Ahn, M.D., Dong Soo Han, M.D., Sun Min Kim, M.D., Hyun Seok Cho, M.D., Tae Jun Byun, M.D., Tae Yeob Kim, M.D., Chang Soo Eun, M.D., Yong Cheol Jeon, M.D. and Joo Hyun Sohn, M.D.
Korean J Gastrointest Endosc 2009;38(2):75-79.   Published online February 27, 2009
AbstractAbstract PDF

Background/Aims: The colonoscopic withdrawal time has been proposed as a quality indicator for colonoscopy, and this is based on the recent evidence that the Colon withdrawal time is associated with adenoma detection rate. In this study, we examined the difference of the polyp detection rates between practicing endoscopists, and we analysed certain factors that might lead to such differences, and particularly the colonoscopic withdrawal time.

Methods: We retrospectively evaluated the colonoscopic procedures that were performed by 7 second-year GI fellows at Hanyang University Guri Hospital. A total of 1,515 colonoscopies were assessed for the polyp detection rate, the insertion time, the withdrawal time, bowel preparation, the size of the detected polyps and the location of polyps.

Results: The median withdrawal time for the case with no polyps removed was 3.6 to 7.1 minutes. There was a strong positive correlation between the colonoscopic withdrawal times and the polyp detection rates (p<0.001). Furthermore, a longer withdrawal time resulted in discovering a higher percentage of small polyps. On comparing groups, the group of colonoscopists with a withdrawal time longer than 6 minutes had a higher rate of detecting polyps (30.7% vs 18.4%, p<0.001).

Conclusions: There is wide range of polyp detection rates among practicing colonoscopists and there is strong positive correlation between the colonoscopic withdrawal times and the rate of detecting polyps. A long enough withdrawal time, perhaps 7 minutes, is needed to raise the rate of detecting polyps during colonoscopy. (Korean J Gastrointest Endosc 2009;38:75-79)

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A Case of Recurrence after Endoscopic Submucosal Dissection of Esophageal Adenocarcinoma Arising from Barrett's Esophagus
Hae Young Jung, M.D., Young Eun Joo, M.D., Sung Bum Cho, M.D., Joon Il Hwang, M.D., Seung Keun Kim, M.D., Wan Sik Lee, M.D., Hyen Soo Kim, M.D. and Sung Kyu Choi, M.D.
Korean J Gastrointest Endosc 2009;38(2):80-84.   Published online February 27, 2009
AbstractAbstract PDF
Surgery is the primary treatment for adenocarcinoma arising from Barrett's esophagus. However, in order to avoid the high risk of complications of surgical resection, many physicians try various endoscopic treatments in cases of early adenocarcinoma and high-grade dysplasia of Barrett's esophagus. Endoscopic submucosal dissection (ESD) is a recently highlighted technique because of its high rate of en bloc resection, but there is controversy about ESD because of the uncertain long-term effect. There is a high risk of local recurrence after endoscopic treatments especially in a long-segment Barrett's esophagus, but there are no reports about this in Korea. This case we report on shows that the early adenocarcinoma arising from a long-segment Barrett's esophagus was curatively removed by ESD, but recurred high-grade dysplasia was detected on the remnant Barrett's esophagus after one year. We report here on a case of recurred esophageal malignancy after successful endoscopic resection of adenocarcinoma from a Barrett's esophagus. (Korean J Gastrointest Endosc 2009;38:80-84)
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A Case of Removing an Esophageal Sharp Foreign Body Using a Surgical Glove
Woo-Seong Jeon, M.D., Kyu-Jong Kim, M.D., Se-Young Park, M.D., Sun-Jung Kim, M.D., Hong-Jun You, M.D., Won Moon, M.D., Moo In Park, M.D. and Seun Ja Park, M.D.
Korean J Gastrointest Endosc 2009;38(2):85-89.   Published online February 27, 2009
AbstractAbstract PDF
Foreign bodies with a sharp margin in the esophagus are often associated with serious complications, such as bleeding, perforation and mediastinitis in the middle of endoscopic removal, as well as impaction in the esophagus wall. Therefore, safe extraction for such patients is essential. The techniques that are performed with an endoscope have been designed with using a protector hood and overtube. Yet the former is not available in Korea, and the later is uncomfortable and limited in diameter. Press-through-packs (PTPs) are commonly used as a package for drugs and they also usually cause esophageal impaction because they have sharp edges. We report here on a case of an impacted PTP in the upper esophagus, and this was successfully extracted endoscopically with using a surgical glove, which is a better safe alternative to above mentioned removal items. (Korean J Gastrointest Endosc 2009;38:85-89)
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A Case of Advanced Gastric Cancer and the First Symptom was a Skin Lesion
Sang Hyun Park, M.D., Sang Dae Lee, M.D., Tae Ung Lee, M.D., Hong Sun Son, M.D., Sang Jin Cho, M.D., Dong Il Byun, M.D., In Sik Park, M.D.* and Su Nam Lee, M.D.
Korean J Gastrointest Endosc 2009;38(2):90-93.   Published online February 27, 2009
AbstractAbstract PDF
Cutaneous metastasis of internal malignancies is rare and the incidence of metastatic skin lesions as the first symptom of disease is only 0.8% for patients with all types of malignancies. Furthermore, cutaneous metastasis from advanced gastric cancer is exceedingly rare. A 43-year-old man presented with a single, symptomatic, erythematous nodule on the chest wall. A biopsy taken from the nodule showed an adenocarcinoma of the poorly differentiated type. An endoscopic examination and biopsy was done and these showed the same histologic findings. We reported here on this unusual case of advanced gastric cancer and the patient's first symptom was a skin lesion. (Korean J Gastrointest Endosc 2009;38:90-93)
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A Case of Intramural Duodenal Hematoma after the Use of the Endoscopic Epinephrine Injection Method for Duodenal Ulcer Bleeding in a Chronic Renal Failure Patient undergoing Maintenance Hemodialysis
Young Yong Ahn, M.D., Soe Hee Ann, M.D., Jeong Eun Yi, M.D., Wook Hyun Lee, M.D., Yeon Oh Jeong, M.D., Eun Hea Kim, M.D., Hea Jung Sung, M.D. and Sang Bum Kang, M.D.
Korean J Gastrointest Endosc 2009;38(2):94-97.   Published online February 27, 2009
AbstractAbstract PDF
An intramural duodenal hematoma has been mostly reported as a consequence of trauma. It can also result from a hematological disorder, anticoagulant drug use and a post-therapeutic endoscopic procedure. Common symptoms of patients with an intramural duodenal hematoma are vomiting and abdominal pain. An intramural duodenal hematoma is rarely accompanied with pancreatitis and cholangitis due to intestinal obstruction. A diagnosis is made by esophagogastroduodenoscopy and the use of an abdominal CT scan. An intramural duodenal hematoma is mainly treated with conservative therapy but it may sometimes be treated with a surgical procedure. We report one case of an intramural duodenal hematoma after performing a therapeutic endoscopic procedure in a chronic renal failure patient undergoing maintenance hemodialysis. (Korean J Gastrointest Endosc 2009;38: 94-97)
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Endoscopy and Colonoscopy in a Situs Inversus Totalis Patient:A Case Report
Seung Hyun Cho, M.D.
Korean J Gastrointest Endosc 2009;38(2):98-102.   Published online February 27, 2009
AbstractAbstract PDF
Situs inversus totalis (SIT) is a very rare autosomal recessive condition that occurs in 1 out of 8,000~20,000 people. Many endoscopic and colonoscopic procedures are performed in SIT patients, and they are difficult due to a complete left-right reversal of the internal organs. However, a throughout review of the endoscopic and colonoscopic procedures in such patients has never been conducted. A previous appendectomy and a large uterine myoma may make a colonoscopic procedure more difficult due to the adhesion and external compression. We performed endoscopy and colonoscopy without pain or complication in a SIT patient who had undergone appendectomy and had a large uterine myoma. We attribute this good result to careful preparation and sticking to the general principles of colonoscopic procedures. (Korean J Gastrointest Endosc 2009;38:98-102)
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A Case of a Small Rectal Carcinoid Tumor with Multiple Liver Metastasis
Eun Kyung Shin, M.D., Seun Ja Park, M.D., Kyu Jong Kim, M.D., Won Moon, M.D., Moo In Park, M.D., Dong Han Im, M.D., Jee Suk Lee, M.D. and Chan Bok Park, M.D.
Korean J Gastrointest Endosc 2009;38(2):103-106.   Published online February 27, 2009
AbstractAbstract PDF
Carcinoid tumors originate from the enterochromaffin cells. Rectal carcinoid tumors comprise 12.6% of all carcinoid tumors and they represent the third largest group of the gut carcinoids. However, a recent report showed that the number of reported cases has increases rapidly, which is probably due to the increased number of colonoscopic examinations. The aggressiveness of rectal carcinoid tumors is determined by the depth of invasion and the presence of metastasis. The clinical course of rectal carcinoid is benign, but these tumors may have a malignant character when the lesion is larger than 2 cm in diameter. We have experienced a case of rectal carcinoid tumor smaller than 2 cm in diameter and the patient had multiple liver metastasis. (Korean J Gastrointest Endosc 2009;38:103-106)
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A Case of Phlebosclerotic Colitis in a Patient of Chronic Renal Failure
Seung Chul Yu, M.D., Jin Il Kim, M.D., So Young Lee, M.D., Yong Jae Park, M.D., Sang Hee Kim, M.D., Dae Young Chung, M.D., Soo-Heon Park, M.D. and Jae Kwang Kim, M.D.
Korean J Gastrointest Endosc 2009;38(2):107-110.   Published online February 27, 2009
AbstractAbstract PDF
Phlebosclerotic colitis is a rare disease sub-entity of ischemic colitis that is caused by venous obstruction due to colonic and mesenteric venous calcifications. Abdominal pain, diarrhea and hematochezia are frequent symptoms of phlebosclerotic colitis. The disease is characterized by typical dark purple mucosa on endoscopy, various venous calcifications on radiological findings, and microscopic findings showing fibrous degeneration, mucosal bleeding and venous wall thickening. A 64-year-old male who was undergoing maintenance hemodialysis was admitted to our hospital due to hematochezia. There was typical dark purple colored mucosa seen on colonoscopy, multiple abdominal calcifications were seen on radiology and diffuse necrosis and inflammatory changes were seen on the histophathology, but there was no mesenteric arterial occlusion seen on abdominal CT. On the basis of these findings, we diagnosed the patient as having phlebosclerotic colitis. To the best of our knowledge, this is the first reported case of phlebosclerotic colitis in Korea. (Korean J Gastrointest Endosc 2009;38:107-110)
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A Case of Delayed Massive Hemorrhage after Endoscopic Resecting a Rectal Carcinoid Tumor
So Mi Kim, M.D., Se Young Yun, M.D., Hoon Choi, M.D., Jae Huan Kong, M.D. and Sung Soo La, M.D.
Korean J Gastrointest Endosc 2009;38(2):111-115.   Published online February 27, 2009
AbstractAbstract PDF
Endoscopic resection is currently accepted as a standard therapy for colon polyp because of its safety and efficiency. The indications for endoscopic resection have been expanded to treat mucosal colon cancer and submucosal tumor. The major complications of endoscopic resection are hemorrhage, perforation and post- polypectomy coagulation syndrome. Hemorrhage is the most common complication, and this can occur immediately following colonoscopic polypectomy or it can be delayed after completion of the procedure. Delayed hemorrhage usually occurs within 7 days and this can stop by itself or the hemorrhage can be controlled endoscopically in the majority of patients, with only the unusual and serious cases requiring transfusion, angiography and surgery. We experienced a case of delayed massive hemorrhage with hypotension that required transfusion 12 days after performing endoscopic resection for rectal carcinoid tumor. We report here on this case to provide a good example and to place emphasis on delayed massive hemorrhage after endoscopic resection. (Korean J Gastrointest Endosc 2009;38: 111-115)
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Endoscopic Drainage Through a Duodenal Fistula in a Patient with a Retroperitoneal Abscess that Developed after Acute Pancreatitis
Hyun Jung Chung, M.D., Seok Jeong, M.D., Don Haeng Lee, M.D., Byoung Do Park, M.D., Yoon Ah Choi, M.D., Hyung Gil Kim, M.D., Yong Woon Shin, M.D. and Young Soo Kim, M.D.
Korean J Gastrointest Endosc 2009;38(2):116-119.   Published online February 27, 2009
AbstractAbstract PDF
The incidence of retroperitoneal abscess with fistula formation after acute pancreatitis is rare, but the mortality rate for patients with this condition is very high. The standard treatment for this condition has been surgical removal and drainage. However, recent studies have shown that percutaneous catheter drainage or noninvasive endoscopic abscess drainage with using endoscopic ultrasonography is effective and safe for the treatment of pancreatic and peripancreatic abscess. A retroperitoneal abscess with duodenal fistula that developed after acute pancreas and its endoscopic treatment has never been reported on in Korea. We experienced a 45-year-old man who had been treated for acute pancreatitis at other hospital, and he was then referred to our hospital and diagnosed as having a retroperitoneal abscess with fistula, which communicated with the third portion of duodenum, as assessed by abdominal CT and duodenoscopy. So we treated him with endoscopic double-pigtailed stent insertion through the fistulous tract and we drained the abscess. Endoscopic drainage may be a suitable alternative for the management of the retroperitoneal abscess with fistula that develops after acute pancreatitis. (Korean J Gastrointest Endosc 2009;38:116-120)
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