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Volume 38(6); June 2009
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The Current Status of Virtual Chromoscopy
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Jin-Oh Kim, M.D. and Tae Hee Lee, M.D.
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Korean J Gastrointest Endosc 2009;38(6):309-322. Published online June 30, 2009
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Abstract
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- Virtual chromoscopy is a novel technology that enhances endoscopic visualization of superficial mucosal surfaces and microvascular architecture. Currently available virtual chromoscopy techniques include narrow band imaging, Fujinon intelligent color enhancement and I-scan. Refinements are expected to improve detection of the lesions, which will lead to further insight into the pathological processes, in turn, providing guidance in selecting the optimal treatment. Presently, we review the currently available literature regarding virtual chromoscopy and provide technical principles, clinical usefulness, and limitations. (Korean J Gastrointest Endosc 2009;38:309-322)
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The Feasibility and Safety of Endoscopic Submucosal Dissection for Gastric Neoplasm in Elderly Korean Patients
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Eung Kap Lee, M.D., Seong Woo Jeon, M.D., Jong Taek Oh, M.D., Soon Hak Lee, M.D., Rack Chun Bae, M.D., Han Jin Jo, M.D., Sun Ik Jang, M.D., Min Kyu Jung, M.D. and Sung Kuk Kim, M.D.
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Korean J Gastrointest Endosc 2009;38(6):323-331. Published online June 30, 2009
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Abstract
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- Background
/Aims: Elderly patients often have high operative risk due to their comorbid diseases, and the feasibility of performing endoscopic submucosal dissection (ESD) for such patients should be investigated. The aim of this study is to evaluate the efficacy and safety of performing ESD in elderly patients.
Methods
From 2005 to 2007, 269 patients with gastric neoplasm were treated by ESD in our hospital. These patients were divided into the elderly patients who were 65 years of age or older and the younger patients. The number of enrolled elderly patients was 123. The en bloc complete resection rate and the complications were assessed and compared with those of the younger patients.
Results
The average age of the old age group of patients was 71.1. Of these patients, 53.7% had comorbid diseases and 51.2% revealed adenocarcinoma. The en bloc plus complete resection rate was 85.4%. Perforation during ESD occurred in 4.1% of the patients, and this was immediately closed with endoclips and then it was managed by conservative medical treatment. Bleeding occurred in 17.9% and there were no patients with severe bleeding. The en bloc plus complete resection rate and the complication rate for the elderly patients were not significantly different from those of the younger patients.
Conclusions
The present study shows that ESD could be a safe and reliable treatment for gastric neoplasms in elderly patients. (Korean J Gastrointest Endosc 2009;38:323-331)
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The Appropriateness of Colonoscopy Indication and the Diagnostic Yield of Colonoscopy
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Choon Young Lee, M.D., Choong Hyeon Lee, M.D., Young Ho Kim, M.D., Jong Woo Lee, M.D., Shin Yeon Kim, M.D.*, Dong Il Park, M.D.* and In Kyung Sung, M.D.†
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Korean J Gastrointest Endosc 2009;38(6):332-338. Published online June 30, 2009
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Abstract
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- Background
/Aims: We wanted to evaluate if the guidelines for appropriately performing colonoscopy by the American Society for Gastrointestinal Endoscopy (ASGE) yield good diagnostic efficacy, and we wanted to assess the appropriateness of referrals.
Methods
A total of 2,412 consecutive patients (1,605 men and 807 women) who were undergoing colonoscopy from September 2006 to February 2007 were prospectively enrolled in the study. The diagnostic yield was defined as the percentage of relevant colonic pathologies of the total number of performed colonoscopies. The 2000 ASGE guidelines were used to assess the appropriateness of the indications for the procedure.
Results
The large majority (64.2%) of patients had colonoscopy for an indication that was considered 'generally indicated', while the procedure was considered 'generally not indicated' for 22.4% of the patients. The diagnostic yield of colonoscopy was significantly higher for the appropriate colonoscopies (59.1%) than for the inappropriate colonoscopies (23.2%). On the multivariable analysis, the diagnostic yield was independently associated with the appropriateness of the indication that was "generally indicated" (odds ratio=9.5) and with the referrals by a gastroenterologist (odds ratio=1.7).
Conclusions
The ASGE guidelines have shown a good diagnostic yield. Further steps are required to update and standardize the guidelines to increase the diagnostic yield. (Korean J Gastrointest Endosc 2009;38:332-338)
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A Case of Locally Invasive Thyroid Papillary Cancer Diagnosed by Esophagoscopy
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Hyo Seung Kang, M.D., Sang Hyun Park, M.D., Dae Jin Kim, M.D., Tae Sik Won, M.D., Sang Jin Cho, M.D. and Tae Ung Lee, M.D.
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Korean J Gastrointest Endosc 2009;38(6):339-342. Published online June 30, 2009
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Abstract
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- Papillary carcinoma is the most common malignant tumor of the thyroid gland, and it only infrequently invades the upper aerodigestive tract. When such invasion does occur, it is a source of significant morbidity as well as mortality. Although most thyroid tumors first clinically manifest as a neck mass, there have been few reports of patients whose initial compliant was a disturbance of the aerodigestive tract. The patient in our present study had no significant past medical history, and esophagoscopy and biopsy revealed papillary adenocarcinoma. We report here on a case of thyroid papillary carcinoma that was diagnosed by esophagoscopic biopsy. (Korean J Gastrointest Endosc 2009;38:339-342)
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A Gastric Glomus Tumor Treated by Endoscopic Resection
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Keun Jong Cho, M.D., Jung-Sun Bag, M.D., Son Ook Choi, M.D., Hyung Jun Kim, M.D., Soon Min Park, M.D., Tae Ho Kim, M.D., Chang-Whan Kim, M.D. and Sok Won Han, M.D.
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Korean J Gastrointest Endosc 2009;38(6):343-347. Published online June 30, 2009
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Abstract
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- Glomus tumors are benign lesions that originate from modified smooth muscle cells of the glomus body. These tumors are commonly observed in the dermis or subcutis, but they are only rarely found in the stomach. We describe here a 37-year- old male patient who presented with intermittent epigastric pain and in whom a submucosal tumor was encountered during performance of upper gastrointestinal endoscopy. A gastrofibroscopy demonstrated a 12 mm sized submucosal mass with central ulceration on the greater curvature-posterior wall of the high body. Endoscopic ultrasonography revealed a circumscribed inhomogeneneous hypo- echoic mass with a focal hyperechoic mass in the third layer of the stomach. We resected the entire mass using an endoscopic resection technique, and there were no complications. Histologically, the tumor cells had uniform small nucleuses with inconspicuous nucleoli. Immunochemical analysis of the tumor cells showed positivity for smooth muscle actin and negativity for CD34, KIT, S100 protein and desmin. This is the first case of a glomus tumor of the stomach that was resected by endoscopic resection. (Korean J Gastrointest Endosc 2009;38:343-347)
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A Case of Successful Clipping of a Colonic Perforation during Diagnostic Colonoscopy
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Soon Ae Kim, M.D., Jae Hak Kim, M.D., Jin Ho Lee, M.D. and Chang Heon Yang, M.D.
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Korean J Gastrointest Endosc 2009;38(6):348-351. Published online June 30, 2009
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Abstract
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- The use of colonoscopy is important to prevent colon cancer. Despite the safety of the colonoscopy procedure, the most common complication of a colonoscopy is perforation, which occurs with a rate of approximately 0.3% during diagnostic colonoscopy and occurs with a rate of approximately 1.1% with the use of therapeutic colonoscopy. Surgery is the treatment of choice for most cases of colonic perforation. With the development of endoscopic devices and techniques, conservative treatment of colonic perforation has been reported by the use of endoscopic clipping. We report here a patient with iatrogenic perforation of the sigmoid colon that was caused by diagnostic colonoscopy. The perforation presented as pneumoretroperitoneum, which was successfully treated with endoscopic clipping. (Korean J Gastrointest Endosc 2009;38:348-351)
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A Case of Idiopathic Mesenteric Phlebosclerosis
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Chang Jae Hur, M.D., Eun Young Kim, M.D., Jang Seok Oh, M.D., Byung Seok Kim, M.D., Ji Min Han, M.D., Jin Tae Jung, M.D., Joong Goo Kwon, M.D. and Ho Gak Kim, M.D.
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Korean J Gastrointest Endosc 2009;38(6):352-355. Published online June 30, 2009
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Abstract
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- Idiopathic mesenteric phlebosclerosis (IMP) is a rare disease of chronic mesenteric ischemia characterized by a thickening of the colonic wall with fibrosis and calcification of the affected veins, which causes ischemic colitis. While the pathogenesis of IMP is unknown, characteristic radiographic, colonoscopic and histologic findings are evident. We report a case of IMP presenting with right lower abdominal pain and diarrhea in a 69-year-old woman. A plain abdominal radiograph revealed thread-like calcification in the colon. Colonoscopy showed dark purple-colored edematous mucosa and erosions in the colon. Histologic examination showed calcification in and around the submucosa and vascular wall. A barium enema demonstrated narrowing and thumb-printing from the ascending to the transverse colon. Abdominal CT disclosed a thickened colonic wall with intramural calcification and calcified mesenteric veins in the colon. (Korean J Gastrointest Endosc 2009;38:352-355)
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A Case of a Primitive Neuroectodermal Tumor Detected from a Duodenal Metastasis
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Sung Hyung Ha, M.D., Young Woon Chang, M.D., Sang Wook Lee, M.D., Jae Young Jang, M.D., Seok Ho Dong, M.D., Hyo Jong Kim, M.D., Byung Ho Kim, M.D. and Rin Chang, M.D.
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Korean J Gastrointest Endosc 2009;38(6):356-359. Published online June 30, 2009
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Abstract
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- A primitive neuroectodermal tumor (PNET) belongs to the Ewing's sarcoma family and is a malignant small round cell tumor of neural crest origin. The most common site of an extraosseous Ewing's sarcoma is in the soft tissue of the body and extremities. A PNET in the ovary is uncommon. A PNET in the ovary is most often found with a metastasis and the prognosis is poor. The diagnosis of this tumor is confirmed following a pathohistological examination of tissue obtained after an open biopsy or surgery, but no case of a PNET has been diagnosed by the use of endoscopy in Korea. We present a case of a primitive neuroectodermal tumor of the ovary, which metastasized to the duodenum as diagnosed by use of an endoscopic biopsy in a 32-year-old woman who presented with abdominal discomfort. (Korean J Gastrointest Endosc 2009;38:356-359)
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Acute Pseudodiverticular Bleeding from a Tuberculous Scar of the Terminal Ileum
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Suh Eun Bae, M.D., Sung-Ae Jung, M.D., Hyun Joo Song, M.D., Min-Jung Kang, M.D., Ji Min Jung, M.D., Seong-Eun Kim, M.D., Ki-Nam Shim, M.D. and Kwon Yoo, M.D.
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Korean J Gastrointest Endosc 2009;38(6):360-363. Published online June 30, 2009
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Abstract
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- Acquired ileal diverticuli are an uncommon condition and the diagnosis is often difficult when bleeding occurs from this source. Tuberculosis mainly involves the terminal ileum and has associated complications such as obstruction, perforation, stricture and bleeding, but rarely presents with pseudodiverticuli with a fistula. A 42-year-old man presented with massive hematochezia for three days. The patient had a history of pulmonary tuberculosis with complete recovery two times. Emergency sigmoidoscopy, esophagoduodenoscopy and computed tomography of the abdomen could not detect the bleeding focus. The next day, colonoscopy was performed, which demonstrated the opening of pseudodiverticuli at the terminal ileum. There was an exposed vessel in one of the pseudodiverticuli. The patient was treated successfully with epinephrine and ethanol sclerotherapy. A subsequent colonoscopy showed that the exposed vessel was completely healed seven days later. We report a case of acute pseudodiverticular bleeding from a tuberculous scar of the terminal ileum with a review of the relevant literature. (Korean J Gastrointest Endosc 2009;38:360-363)
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A Case of Polyarteritis Nodosa That Presented as Hemobilia
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Joo Wook Sung, M.D., Yun Jeong Lim, M.D., Jae Hyun Kwon, M.D.*, Kyung Jo Kim, M.D.† and Jin Ho Lee, M.D.
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Korean J Gastrointest Endosc 2009;38(6):364-367. Published online June 30, 2009
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Abstract
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- Hemobilia is defined as hemorrhage into the biliary tract, and the patients with hemobilia present with abdominal pain, jaundice and gastrointestinal bleeding. The causes of hemobilia are traumatic or operative injury to the liver or bile ducts, intraductal rupture of the hepatic abscess or aneurysm of the hepatic artery. Cholecystitis can also develop in patients with hemobilia. Polyarteritis nodosa (PAN) is a multisystem, necrotizing vasculitis of the small and medium-sized muscular arteries and patients with this illness may present with fever, sweats, weight loss, severe arthralgia and myalgia. Mesentery artery involvement that can result in gastrointestinal hemorrhage, bowel infarction and perforation is rare, yet very serious in patients with PAN. We report here on a rare case of PAN that presented as hemobilia due to rupture of a hepatic arterial aneurysm. (Korean J Gastrointest Endosc 2009;38:364-367)
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A Case of Peribiliary Cysts
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Pyo Jun Kim, M.D., Dae Hwan Kang, M.D., Woo Jin Jeong, M.D., Il Du Kim, M.D., Jae Sup Eum, M.D., Cheol Woong Choi, M.D. and Geun Am Song, M.D.
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Korean J Gastrointest Endosc 2009;38(6):368-370. Published online June 30, 2009
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Abstract
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- Hepatic peribiliary cysts are characterized by multiple tiny cysts of peribiliary glands located in the hilum of the large portal tracts. A 54-year-old man was diagnosed as multiple peribiliary cysts by a magnetic resonance cholangiopancreatogram. A course of observation was taken, since surgery due to misdiagnosis of peribiliary cysts as a malignancy is a possibility. The present case highlights the need for precise diagnosis and observation of peribiliary cysts. (Korean J Gastrointest Endosc 2009;38:368-370)
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