Clinical Endoscopy

Giant Rugae in Helicobacter pylori-Infected Stomachs: Sun-Young Lee; Clin Endosc 2021;54(1):1-3. Published online January 21, 2021; DOI: https://doi.org/10.5946/ce.2021.007

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Preparation of 3D-printed gastric models with biomimetic mechanical, topographical and fluid dynamic properties
Yu-Tung Hsu, Shiao-Pieng Lee, Chung-Hsing Li, Ming-Hua Ho, Chen-Yu Kao
Journal of the Taiwan Institute of Chemical Engineers.2024; 160: 105389. CrossRef
Type A, Type B, and Non-atrophic Gastritis
Sun-Young Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(2): 108. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Serum Assay Findings after Successful Helicobacter pylori Eradication
Sun-Young Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2021; 21(4): 287. CrossRef

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Colon Capsule Endoscopy: An Alternative for Conventional Colonoscopy?: Britt B.S.L. Houwen, Evelien Dekker; Clin Endosc 2021;54(1):4-6. Published online January 21, 2021; DOI: https://doi.org/10.5946/ce.2021.047

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TOP 100 and detection of colorectal lesions in colon capsule endoscopy: more than meets the eye
Tiago Lima Capela, Cátia Arieira, Sofia Xavier, Tiago Cúrdia Gonçalves, Pedro Boal Carvalho, Bruno Rosa, José Cotter
European Journal of Gastroenterology & Hepatology.2024; 36(9): 1087. CrossRef
Diagnostic Evaluation of Solid Pancreatic Lesions: Endoscopic Ultrasound-Guided Fine Needle Aspiration Versus Percutaneous Ultrasound-Guided Core Needle Biopsy
Ismail Caymaz, Nargiz Afandiyeva
CardioVascular and Interventional Radiology.2023; 46(11): 1596. CrossRef
Examination of Entire Gastrointestinal Tract: A Perspective of Mouth to Anus (M2A) Capsule Endoscopy
Ji Hyung Nam, Kwang Hoon Lee, Yun Jeong Lim
Diagnostics.2021; 11(8): 1367. CrossRef

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Is Carcinoembryonic Antigen the Holy Grail for Pancreatic Cyst Risk Stratification?: Ahmad Najdat Bazarbashi, Linda S. Lee; Clin Endosc 2021;54(1):7-8. Published online January 25, 2021; DOI: https://doi.org/10.5946/ce.2021.046

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The Clinical and Metabolic Effects of Intragastric Balloon on Morbid Obesity and Its Related Comorbidities: Joon Hyun Cho, Mohammad Bilal, Min Cheol Kim, Jonah Cohen, The Study Group for Endoscopic Bariatric and Metabolic Therapies of the Korean Society of Gastrointestinal Endoscopy; Clin Endosc 2021;54(1):9-16. Published online January 29, 2021; DOI: https://doi.org/10.5946/ce.2020.302

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Obesity is becoming increasingly prevalent worldwide, and its metabolic sequelae lead to a significant burden on healthcare resources. Options for the management of obesity include lifestyle modification, pharmacological treatment, surgery, and endoscopic bariatric therapies (EBTs). Among these, EBTs are more effective than diet and lifestyle modification and are less invasive than bariatric surgery. In recent years, there have been significant advances in technologies pertaining to EBTs. Of all the available EBTs, there is a significant amount of clinical experience and published data regarding intragastric balloons (IGBs) because of their comparatively long development period. Currently, the United States Food and Drug Administration (FDA) has approved three IGBs, including Orbera (Apollo Endosurgery, Austin, TX, USA), ReShape Duo (ReShape Medical, San Clemente, CA, USA), and Obalon (Obalon Therapeutics, Carlsbad, CA, USA). The aim of this review is to summarize the available literature on the efficacy of IGBs in weight loss and their impact on obesity-related metabolic diseases.

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Role of endoscopic duodenojejunal bypass liner in obesity management and glycemic control
Willian Ferreira Igi, Victor Lira de Oliveira, Ayah Matar, Diogo Turiani Hourneaux de Moura
Clinical Endoscopy.2024; 57(3): 309. CrossRef
Evaluating Weight Loss Efficacy in Obesity Treatment with Allurion’s Ingestible Gastric Balloon: A Retrospective Study Utilizing the Scale App Health Tracker
Danut Dejeu, Paula Dejeu, Paula Bradea, Anita Muresan, Viorel Dejeu
Clinics and Practice.2024; 14(3): 765. CrossRef
Efficacy and safety of intragastric balloon for obesity in Korea
Kwang Gyun Lee, Seung-Joo Nam, Hyuk Soon Choi, Hang Lak Lee, Jai Hoon Yoon, Chan Hyuk Park, Kyoung Oh Kim, Do Hoon Kim, Jung-Wook Kim, Won Sohn, Sung Hoon Jung
Clinical Endoscopy.2023; 56(3): 333. CrossRef
How effective is intragastric balloon insertion as an obesity treatment in Korea?
Youngdae Kim
Clinical Endoscopy.2023; 56(3): 310. CrossRef
Overview on the endoscopic treatment for obesity: A review
Maheeba Abdulla, Nafeesa Mohammed, Jehad AlQamish
World Journal of Gastroenterology.2023; 29(40): 5526. CrossRef
Endoscopic Bariatric Therapy for Obesity and Metabolic Syndrome
Sang Pyo Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(4): 247. CrossRef
Status of bariatric endoscopy–what does the surgeon need to know? A review
Diogo Turiani Hourneaux de Moura, Anna Carolina Batista Dantas, Igor Braga Ribeiro, Thomas R McCarty, Flávio Roberto Takeda, Marco Aurelio Santo, Sergio Carlos Nahas, Eduardo Guimarães Hourneaux de Moura
World Journal of Gastrointestinal Surgery.2022; 14(2): 185. CrossRef
Various Novel and Emerging Technologies in Endoscopic Bariatric and Metabolic Treatments
Hee Kyong Na, Diogo Turiani Hourneaux De Moura
Clinical Endoscopy.2021; 54(1): 25. CrossRef

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The Efficacy and Safety of Endoscopic Sleeve Gastroplasty as an Alternative to Laparoscopic Sleeve Gastrectomy: Jin Young Yoon, Román Turró Arau, The study group for endoscopic bariatric and metabolic therapies in the Korean Society of Gastrointestinal Endoscopy; Clin Endosc 2021;54(1):17-24. Published online January 22, 2021; DOI: https://doi.org/10.5946/ce.2021.019

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Endoscopic sleeve gastroplasty (ESG) is a therapeutic endoscopic technique for reducing the size of the gastric reservoir in obese patients, using a full-thickness endoscopic suturing device. The effectiveness of ESG in weight loss is significantly greater than that of high-intensity diet and lifestyle therapy and lower than that of laparoscopic sleeve gastrectomy (LSG). The efficacy at 12 months after ESG in terms of percentage of total body weight loss and excess body weight loss was approximately 16% and 60%, respectively. The well-known predictive factors for increased weight loss by ESG are good compliance with regular monitoring and post-procedure care involving a multidisciplinary team approach. Although the underlying mechanism of weight loss induced by ESG is debatable, delayed gastric emptying and early satiation are some of the proposed mechanisms. The pooled rate of adverse events after ESG reported in several meta-analysis studies ranged from 1.5% to 2.3% and the incidence of new-onset gastroesophageal reflux disease after ESG was negligible, indicating that ESG has a superior safety profile to LSG. Moreover, ESG reduced the risk of obesity-related metabolic comorbidities, evidenced by the reduction in HbA1c level, systolic blood pressure, triglyceride level, and risk of hepatic steatosis and fibrosis; it even improved the quality of life. ESG could be considered safe and qualify as an alternative treatment to LSG.

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Performance of Endoscopic Sleeve Gastroplasty by Obesity Class in the United States Clinical Setting
Khushboo Gala, Vitor Brunaldi, Christopher McGowan, Reem Z. Sharaiha, Daniel Maselli, Brandon Vanderwel, Prashant Kedia, Michael Ujiki, Eric Wilson, Eric J. Vargas, Andrew C. Storm, Barham K. Abu Dayyeh
Clinical and Translational Gastroenterology.2024; 15(1): e00647. CrossRef
Recent advances in therapeutic interventions of polycystic ovarian syndrome
Sakshi Upendra Lad, Ganesh Sunil Vyas, Sharfuddin Mohd, Vijay Mishra, Sheetu Wadhwa, Saurabh Singh, Vancha Harish
Obesity Medicine.2024; 48: 100543. CrossRef
Fundus-to-Antrum Ratio Measured with Fluoroscopy within One Week after Endoscopic Sleeve Gastroplasty Predicts Total Body Weight Loss over Time
Kaveh Hajifathalian, Kamal Amer, Dema Shamoon, Donevan Westerveld, Louis Aronne, Amit Mehta, Angela Wong, Grace Lo, Sarah Oh, Andrea Siobhan Kierans, Kamal M. Hassan, Ali Lahooti, Reem Z. Sharaiha
Journal of Clinical Medicine.2024; 13(13): 3933. CrossRef
Endoscopic treatment of obesity: A protocol of updated systematic review with network meta-analysis of randomized controlled trials
Eun Jeong Gong, Chang Seok Bang, Gwang Ho Baik, Dong Keon Yon
PLOS ONE.2024; 19(9): e0308410. CrossRef
The Efficacy Comparison of Endoscopic Bariatric Therapies: 6-Month Versus 12-Month Intragastric Balloon Versus Endoscopic Sleeve Gastroplasty
K. Kozłowska-Petriczko, K. M. Pawlak, K. Wojciechowska, A. Reiter, Ł. Błaszczyk, J. Szełemej, J. Petriczko, A. Wiechowska-Kozłowska
Obesity Surgery.2023; 33(2): 498. CrossRef
Endobariatrics: a Still Underutilized Weight Loss Tool
Niel Dave, Enad Dawod, Okeefe L. Simmons
Current Treatment Options in Gastroenterology.2023; 21(2): 172. CrossRef
Safety and efficacy of endoscopic sleeve gastroplasty and laparoscopic sleeve gastrectomy in obese type 2 diabetes patients
Vimal Thomas, Tarun Kumar Suvvari, Anu Varghese, Nikhat Kousar Ahmed, Yasmine Tarek Elsherif, Aasim Akthar Ahmed
Surgery Open Digestive Advance.2023; 11: 100098. CrossRef
Endoscopic Sleeve Gastroplasty: A Practice Pattern Survey
James D. Haddad, Jaime P. Almandoz, Victoria Gomez, Allison R. Schulman, Jay D. Horton, Jeffrey Schellinger, Sarah E. Messiah, M. Sunil Mathew, Elisa Morales Marroquin, Anna Tavakkoli
Obesity Surgery.2023; 33(8): 2434. CrossRef
Endoscopic Sleeve Gastroplasty (ESG) Versus Laparoscopic Sleeve Gastroplasty (LSG): A Comparative Review
Basil N Nduma, Kelly A Mofor, Jason Tatang, Loica Amougou, Stephen Nkeonye, Princess Chineme, Chukwuyem Ekhator, Solomon Ambe
Cureus.2023;[Epub] CrossRef
Operator-specific outcomes in endoscopic sleeve gastroplasty: a propensity-matched analysis of the US population using a multicenter database
Hassam Ali, Faisal Inayat, Talia F. Malik, Pratik Patel, Gul Nawaz, Sobaan Taj, Attiq Ur Rehman, Arslan Afzal, Rizwan Ishtiaq, Muhammad Sohaib Afzal, Rashmi Advani, Rabindra R. Watson
Baylor University Medical Center Proceedings.2023; 36(5): 592. CrossRef
The surgical management of obesity
Alan Askari, Periyathambi Jambulingam, Roy Gurprashad, Omer Al-Taan, Tanveer Adil, Aruna Munasinghe, Vigyan Jain, Farhan Rashid, Douglas Whitelaw
Clinical Medicine.2023; 23(4): 330. CrossRef
Endoluminal bariatric and metabolic therapies: state-of-the-art
Nader Bakheet, Dilhana Badurdeen, Adrian Sartoretto, Vivek Kumbhari
Current Opinion in Gastroenterology.2023; 39(5): 362. CrossRef
Bariatric and metabolic surgery in patients with low body mass index: an online survey of 543 bariatric and metabolic surgeons
Shahab Shahabi Shahmiri, Chetan Parmar, Wah Yang, Panagiotis Lainas, Sjaak Pouwels, Amir Hossein DavarpanahJazi, Sonja Chiappetta, Yosuke Seki, Islam Omar, Ramon Vilallonga, Radwan Kassir, Syed Imran Abbas, Ahmad Bashir, Rishi Singhal, Lilian Kow, Mohamma
BMC Surgery.2023;[Epub] CrossRef
Summarizing Consensus Guidelines on Obesity Management
Reem Z. Sharaiha, Scott Shikora, Kevin P. White, Guilherme Macedo, Jim Toouli, Lillian Kow
Journal of Clinical Gastroenterology.2023; 57(10): 967. CrossRef
Endoscopic sleeve gastroplasty reintervention score using supervised machine learning
Hassam Ali, Pratik Patel, Talia Farrukh Malik, Rahul Pamarthy, Babu P. Mohan, Ravishankar Asokkumar, Gontrand Lopez-Nava, Douglas G. Adler
Gastrointestinal Endoscopy.2023; 98(5): 747. CrossRef
Endoscopic sleeve gastroplasty: results from a single surgical bariatric centre
Lino Polese, Luca Prevedello, Amanda Belluzzi, Emilia Giugliano, Alice Albanese, Mirto Foletto
Updates in Surgery.2022; 74(6): 1971. CrossRef
Various Novel and Emerging Technologies in Endoscopic Bariatric and Metabolic Treatments
Hee Kyong Na, Diogo Turiani Hourneaux De Moura
Clinical Endoscopy.2021; 54(1): 25. CrossRef
The Effect of Endoscopic Bariatric and Metabolic Therapies on Gastroesophageal Reflux Disease
Su-Young Kim
Medicina.2021; 57(8): 737. CrossRef

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Various Novel and Emerging Technologies in Endoscopic Bariatric and Metabolic Treatments: Hee Kyong Na, Diogo Turiani Hourneaux De Moura, The Study Group for Endoscopic Bariatric and Metabolic Therapies of the Korean Society of Gastrointestinal Endoscopy; Clin Endosc 2021;54(1):25-31. Published online January 29, 2021; DOI: https://doi.org/10.5946/ce.2021.021

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Obesity, along with its comorbidities, has become a significant public health concern worldwide. Bariatric surgery is considered the most effective treatment modality; however, only 2% of patients with obesity undergo bariatric surgery. Endoscopic bariatric and metabolic therapies (EBMTs) are emerging alternatives to traditional bariatric surgery for patients who are not eligible for or do not prefer surgical treatment. EBMTs are generally categorized as space-occupying, gastric restrictive, aspiration, and small bowel therapies. We aimed to review various non-balloon and non-gastroplasty devices with available clinical data and discuss the possible mechanisms of action, efficacy, and safety profile of these EMBTs.

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Role of endoscopic duodenojejunal bypass liner in obesity management and glycemic control
Willian Ferreira Igi, Victor Lira de Oliveira, Ayah Matar, Diogo Turiani Hourneaux de Moura
Clinical Endoscopy.2024; 57(3): 309. CrossRef
Intragastric Balloons
D.T.H. de Moura, Sergio A. Sánchez-Luna, Adriana Fernandes Silva, Alexandre Moraes Bestetti
Gastrointestinal Endoscopy Clinics of North America.2024;[Epub] CrossRef
Current State of Endoscopic Bariatric Therapies
Lee Ying, Samuel Butensky, Ysabel Ilang-Ying, Saber Ghiassi
Surgical Clinics of North America.2024;[Epub] CrossRef
Effectiveness and Safety of the Allurion Swallowable Intragastric Balloon for Short-term Weight Loss: A Systematic Review and Meta-analysis
Adriana Fernandes Silva, Alexandre Moraes Bestetti, Angelo So Taa Kum, Beanie Conceição Medeiros Nunes, Matheus de Oliveira Veras, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura
Obesity Surgery.2024;[Epub] CrossRef
The Effectiveness and Safety of the Duodenal-Jejunal Bypass Liner (DJBL) for the Management of Obesity and Glycaemic Control: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Erika Yuki Yvamoto, Diogo Turiani Hourneaux de Moura, Igor Mendonça Proença, Epifanio Silvino do Monte Junior, Igor Braga Ribeiro, Pedro Henrique Boraschi Vieira Ribas, Matheus Cândido Hemerly, Victor Lira de Oliveira, Sergio A. Sánchez-Luna, Wanderley Ma
Obesity Surgery.2023; 33(2): 585. CrossRef
A Comprehensive Review on Bariatric Endoscopy: Where We Are Now and Where We Are Going
Aurelio Mauro, Francesca Lusetti, Davide Scalvini, Marco Bardone, Federico De Grazia, Stefano Mazza, Lodovica Pozzi, Valentina Ravetta, Laura Rovedatti, Carmelo Sgarlata, Elena Strada, Francesca Torello Viera, Letizia Veronese, Daniel Enrique Olivo Romero
Medicina.2023; 59(3): 636. CrossRef
Endoscopic Bariatric Therapy for Obesity and Metabolic Syndrome
Sang Pyo Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(4): 247. CrossRef
The Effect of Endoscopic Bariatric and Metabolic Therapies on Gastroesophageal Reflux Disease
Su-Young Kim
Medicina.2021; 57(8): 737. CrossRef

4,882 View
160 Download
5 Web of Science
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Trends of Colorectal Cancer Prevalence in Kazakhstan Related to Screening: Alma Zhylkaidarova, Dilyara Kaidarova, Kanat Batyrbekov, Oxana Shatkovskaya, Dinara Begimbetova; Clin Endosc 2021;54(1):32-37. Published online May 25, 2020; DOI: https://doi.org/10.5946/ce.2019.198

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We carried out an analysis of the total incidence of colon cancer throughout Kazakhstan. Retrospectively, according to the regional reports on endoscopic screening, the study showed an increase in the age-related incidence of colorectal cancer (CRC) cases from 2004–2008 to 2009–2014. The peak of morbidity in both periods was noted in the age category of >70 years. The indicators of the territorial distribution of CRC incidence make it possible to divide the regions into areas with low or high rates of CRC. Specific indicators showed newly diagnosed cases of CRC stages I, II, III, and IV in 2004–2018. The incidence rates of stages I and II showed a two-fold increase (35%–67.4%) and the incidence of stage IV showed a decline from 19.3% to 13.1% and of stage III from 45.7% to 19.5% from 2004 to 2018, respectively. An analysis of CRC incidence throughout Kazakhstan showed an increase in the overall incidence. Since population-based CRC screening was introduced in 2011, the morbidity was found to increase for stages I and II.

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Colorectal cancer’s burden attributable to a diet high in processed meat in the Belt and Road Initiative countries
Gu Liu, Chang-Min Li, Fei Xie, Qi-Lai Li, Liang-Yan Liao, Wen-Jun Jiang, Xiao-Pan Li, Guan-Ming Lu
World Journal of Gastrointestinal Oncology.2024; 16(1): 182. CrossRef
Serum Interleukins 8, 17, and 33 as Potential Biomarkers of Colon Cancer
Constantin-Dan Tâlvan, Liviuța Budișan, Elena-Teodora Tâlvan, Valentin Grecu, Oana Zănoagă, Cosmin Mihalache, Victor Cristea, Ioana Berindan-Neagoe, Călin Ilie Mohor
Cancers.2024; 16(4): 745. CrossRef
Kazakh version of the beck depression inventory: Validation study in female cancer patients
Indira Karibayeva, Botagoz Turdaliyeva, Nor Zuraida Zainal, Fatima Bagiyarova, Dinara Kussainova
Heliyon.2023; 9(7): e18146. CrossRef
Colorectal Cancer Screening with Computed Tomography Colonography: Single Region Experience in Kazakhstan
Jandos Amankulov, Dilyara Kaidarova, Zhamilya Zholdybay, Marianna Zagurovskaya, Nurlan Baltabekov, Madina Gabdullina, Akmaral Ainakulova, Dias Toleshbayev, Alexandra Panina, Elvira Satbayeva, Zhansaya Kalieva
Clinical Endoscopy.2022; 55(1): 101. CrossRef
Association of four genetic variants with colorectal cancer in Kazakhstan population
Yevgeniya Kolesnikova, Dmitriy Babenko, Irina Kadyrova, Svetlana Kolesnichenko, Lyudmila Akhmaltdinova, Ilya Korshukov, Naylya Kabildina, Valentina Sirota, Vera Zhumaliyeva, Dana Taizhanova, Dmitriy Vazenmiller, Anar Turmukhambetova
Oncotarget.2021; 12(21): 2215. CrossRef

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The Role of Needle-Based Confocal Laser Endomicroscopy in the Evaluation of Pancreatic Cystic Lesions: A Systematic Review: Yung Ka Chin, Clement Chun Ho Wu, Damien Meng Yew Tan; Clin Endosc 2021;54(1):38-47. Published online March 31, 2020; DOI: https://doi.org/10.5946/ce.2019.200-IDEN

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The prevalence of pancreatic cystic lesions (PCLs) has increased recently due to the increased use of cross-sectional abdominal imaging and the ageing global population. Current diagnostic techniques are inadequate to distinguish between PCLs that require surgery, close surveillance, or expectant management. This has resulted in increased morbidity from both inappropriately aggressive and conservative management strategies. Needle-based confocal laser endomicroscopy (nCLE) has allowed microscopic examination and visual delineation of the surface epithelium of PCLs. Landmark studies in this decade have correlated nCLE and histological findings and identified characteristics differentiating various types of PCLs. Subsequent studies have confirmed the high diagnostic yield of nCLE and its diagnostic utility in PCLs with an equivocal diagnosis. Moreover, nCLE has been shown to improve the diagnostic yield of PCLs. This will help avoid unnecessary pancreatic surgery, which carries significant morbidity and mortality risks. The early detection of high-grade dysplasia in PCLs will provide early surgical treatment and improve outcomes for pancreatic cancer. Despite the high upfront cost of nCLE, the improved diagnostic accuracy and resultant appropriate management have resulted in improved cost effectiveness. Refining the procedure technique and limiting the procedure length have significantly improved the safety of nCLE. A structured training program and device improvements to allow more complete mapping of the pancreatic cyst epithelium will be crucial for the widespread adoption of this promising technology.

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Molecular Pathology of Pancreatic Cystic Lesions with a Focus on Malignant Progression
Yan Hu, Dan Jones, Ashwini K. Esnakula, Somashekar G. Krishna, Wei Chen
Cancers.2024; 16(6): 1183. CrossRef
Applications and Prospects of Artificial Intelligence-Assisted Endoscopic Ultrasound in Digestive System Diseases
Jia Huang, Xiaofei Fan, Wentian Liu
Diagnostics.2023; 13(17): 2815. CrossRef
EUS-guided fine needle aspiration-based clues to mistaken or uncertain identity: serous pancreatic cysts
Michele T. Yip-Schneider, Rodica Muraru, Rachel C. Kim, Howard H. Wu, Stuart Sherman, Aditya Gutta, Mohammad A. Al-Haddad, John M. Dewitt, C. Max Schmidt
HPB.2023; 25(12): 1587. CrossRef
Current trends in the management of pancreatic cystic neoplasms in Korea: a national survey
Hyung Ku Chon, Sung Hoon Moon, Sang Wook Park, Woo Hyun Paik, Chang Nyol Paik, Byoung Kwan Son, Tae Jun Song, Dong Won Ahn, Eaum Seok Lee, Yun Nah Lee, Yoon Suk Lee, Jae Min Lee, Tae Joo Jeon, Chang-Hwan Park, Kwang Bum Cho, Dong Wook Lee
The Korean Journal of Internal Medicine.2022; 37(1): 63. CrossRef
Confocal Laser Endomicroscopy in the Diagnosis of Biliary and Pancreatic Disorders: A Systematic Analysis
Do Han Kim, Somashekar G. Krishna, Emmanuel Coronel, Paul T. Kröner, Herbert C. Wolfsen, Michael B. Wallace, Juan E. Corral
Clinical Endoscopy.2022; 55(2): 197. CrossRef
Accuracy and agreement of a large panel of endosonographers for endomicroscopy-guided virtual biopsy of pancreatic cystic lesions
Jorge D. Machicado, Bertrand Napoleon, Anne Marie Lennon, Samer El-Dika, Stephen P. Pereira, Damien Tan, Rahul Pannala, Mohit Girotra, Pradermchai Kongkam, Helga Bertani, Yunlu Feng, Hao Sijie, Ning Zhong, Vincent Valantin, Sarah Leblanc, Alice Hinton, So
Pancreatology.2022; 22(7): 994. CrossRef
Pancreatic Cystic Lesions: A Focused Review on Cyst Clinicopathological Features and Advanced Diagnostics
Wei Chen, Nehaal Ahmed, Somashekar G. Krishna
Diagnostics.2022; 13(1): 65. CrossRef
Diagnostic Value of Endomicroscopy for Gastrointestinal Diseases: New Possibilities and Concepts
Ralf Kiesslich
Techniques and Innovations in Gastrointestinal Endoscopy.2021; 23(1): 57. CrossRef

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Changes in Policy and Endoscopic Procedures during the 2019 Coronavirus Disease Outbreak: A Single Center Experience: Adi Lahat, Avidan Benjamin; Clin Endosc 2021;54(1):48-54. Published online November 6, 2020; DOI: https://doi.org/10.5946/ce.2020.132

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Background
/Aims: The coronavirus disease-19 (COVID-19) pandemic forced endoscopy units to enact major changes on daily practice and policy. The Chaim Sheba Medical Center is a tertiary referral center located in the center of Israel, and serves cities with high infection rates. Our aim was to review the policies enacted during this outbreak and study their influence on the performance of endoscopic procedures.
Methods
Following the revision of work protocols, personnel were divided into two permanent and physically separate working groups and screening procedures were rescheduled. Relevant data including the number of endoscopic examinations, type of procedure performed, and patient referrals and indications were taken from a computerized database and evaluated. The study included data for January–March 2018–2020, and a comparison among the data from each year was performed.
Results
As of March 2020, the total number of endoscopic examinations performed reduced by 44% (p<0.0001) as compared to previous years, gastroscopy examinations reduced by 39% (p=0.02), and lower endoscopy procedures reduced by 57% (p<0.0001). Meanwhile, the number of advanced endoscopic procedures performed remained consistent with previous years. The indications for performance of gastroscopy and lower endoscopy were different in March 2020, while these remained unchanged for advanced endoscopic procedures.
Conclusions
The current policy appears to serve both our initial goals: protecting personnel and patients’ safety and minimizing potential damage from delayed endoscopic procedures. A longer term follow-up study is needed in order to fully analyze our results.

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Association of COVID-19 Pandemic with Colorectal Cancer Screening: Impact of Race/Ethnicity and Social Vulnerability
Muhammad Muntazir Mehdi Khan, Muhammad Musaab Munir, Selamawit Woldesenbet, Yutaka Endo, Mujtaba Khalil, Diamantis Tsilimigras, Alan Harzman, Emily Huang, Matthew Kalady, Timothy M. Pawlik
Annals of Surgical Oncology.2024; 31(5): 3222. CrossRef
Setting up a three‐stage pre‐endoscopy triage during the coronavirus disease 2019 pandemic: A multicenter observational study
Tao‐Chieh Liu, Chen‐Ling Peng, Fang‐Yu Hsu, Li‐Chun Chang, Hsiu‐Po Wang, Wei‐Kuo Chang
DEN Open.2023;[Epub] CrossRef
Impact of the COVID-19 Pandemic on Colorectal Cancer Screening: a Systematic Review
Afrooz Mazidimoradi, Azita Tiznobaik, Hamid Salehiniya
Journal of Gastrointestinal Cancer.2022; 53(3): 730. CrossRef
The impact of the COVID-19 pandemic on colorectal and gastric cancer diagnosis, disease stage and mortality
Naim Abu-Freha, Reut Hizkiya, Muhammad Abu-Abed, Tal Michael, Binil Mathew Jacob, Keren Rouvinov, Doron Schwartz, Avraham Reshef, Uri Netz, Ilia Pinsk, Ohad Etzion
Frontiers in Medicine.2022;[Epub] CrossRef
The Dramatic Change in Endoscopic Activities Following the Coronavirus Disease 2019 Outbreak. Is It Evolution?
Kook Hyun Kim
Clinical Endoscopy.2021; 54(3): 445. CrossRef
Protecting Your Endoscopy Unit during the COVID-19 Pandemic
Hyeong Ho Jo, Eun Young Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2021; 21(3): 239. CrossRef
Capsule Endoscopy in Crohn’s Disease—From a Relative Contraindication to Habitual Monitoring Tool
Adi Lahat, Ido Veisman
Diagnostics.2021; 11(10): 1737. CrossRef

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Confocal Laser Endomicroscopic Findings of Refractory Erosive Reflux Disease versus Non-Erosive Reflux Disease with Anti-Reflux Mucosectomy: An in vivo and ex vivo Study: Eunju Jeong, In Kyung Yoo, Abdullah Özgür Yeniova, Dong Keon Yon, Joo Young Cho; Clin Endosc 2021;54(1):55-63. Published online May 7, 2020; DOI: https://doi.org/10.5946/ce.2020.040

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Background
/Aims: To date, there is no standard tool to diagnose gastroesophageal reflux disease (GERD). Typically, GERD is a non-erosive reflux disease (NERD) that does not present endoscopic abnormalities. Confocal laser endomicroscopy (CLE) has been shown to be an effective tool to identify and diagnose GERD. We aimed to investigate the cellular and vascular changes in vivo and ex vivo through CLE in patients with GERD.
Methods
Patients with refractory GERD who underwent mucosectomy were recruited. The distal esophagus was observed in vivo using CLE. Mucosectomy tissue was stained with acriflavine and CLE image was obtained ex vivo. We compared cellular and vascular changes in CLE between erosive reflux disease (ERD), NERD, and a control group.
Results
Eleven patients who underwent anti-reflux mucosectomy and five control patients were enrolled in the study. Patients with ERD and NERD presented greater dilated intercellular space than patients in the control group on CLE image. The diameter, number, and cross-sectional area of the intra-papillary capillary loops (IPCLs) were significantly larger in the ERD group than in the NERD group. The irregular shape of the IPCLs were observed in both patients with ERD and NERD.
Conclusions
The irregular shape of the IPCLs were significantly correlated with a positive diagnosis of GERD. CLE may diagnose NERD with high sensitivity and accuracy.

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Outcomes of Endoscopic Antireflux Mucosectomy for the Treatment of Gastroesophageal Reflux Disease
Martin Galvarini, Cristian A. Angeramo, Javier Kerman, Rubén Balmaceda, Ignacio Debes, Fernando A.M. Herbella, Francisco Schlottmann
Journal of Clinical Gastroenterology.2024; 58(9): 851. CrossRef
Anti-reflux mucosal resection for treatment of refractory gastro-oesophageal reflux disease: Efficacy and impact on perioperative indicators
Xing-Feng Ge, Xian Zhu, Fei Min, Jian-Wei Shen
World Chinese Journal of Digestology.2023; 31(4): 157. CrossRef

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Efficacy of the Envelope Method in Applying Polyglycolic Acid Sheets to Post-Endoscopic Submucosal Dissection Ulcers in Living Pigs: Hiroya Sakaguchi, Toshitatsu Takao, Yoshitaka Takegawa, Yuki Koga, Kazunori Yamanaka, Masataka Sagata, Shinwa Tanaka, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama; Clin Endosc 2021;54(1):64-72. Published online July 16, 2020; DOI: https://doi.org/10.5946/ce.2020.014

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Background
/Aims: Application of polyglycolic acid (PGA) sheets using fibrin glue in post-endoscopic submucosal dissection (ESD) ulcers to prevent bleeding has been reported to be difficult with the conventional delivery method because of gravity. This study assessed the usefulness of the envelope-based delivery system with and against gravity in living pigs.
Methods
PGA sheets were applied on post-ESD ulcers with and against gravity six times each using the conventional and envelope methods, respectively. The PGA sheet delivery time and the endoscopic and histological findings of the treated ulcer floors were compared.
Results
With gravity, the median PGA sheet application time was 1.00 (0.68–1.30) min/cm² and 0.32 (0.18–0.52) min/cm² with the conventional and envelope techniques (p=0.002), respectively, and against gravity, it was 1.20 (1.13–1.63) min/cm² and 0.50 (0.39–0.58) min/cm² (p=0.002), respectively. Against gravity, the endoscopic and histological findings revealed that the conventional group had insufficient fixation of the PGA sheets, but the envelope groups had sufficient fixation. The results with gravity were similar between the groups.
Conclusions
The envelope method makes it possible to deliver PGA sheets to the stomach quickly and cover ulcers appropriately both with and against gravity in living pigs.

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Endoscopic sealing hemostasis with polyglycolic acid sheet and fibrin glue as a novel endoscopic hemostatic technique: a report of three cases
Kai Korekawa, Atsushi Kunimitsu
Clinical Journal of Gastroenterology.2024; 17(4): 626. CrossRef
Clinical Impact of Different Reconstruction Methods on Remnant Gastric Cancer at the Anastomotic Site after Distal Gastrectomy
Kei Matsumoto, Shinwa Tanaka, Takashi Toyonaga, Nobuaki Ikezawa, Mari Nishio, Masanao Uraoka, Tomoatsu Yoshihara, Hiroya Sakaguchi, Hirofumi Abe, Tetsuya Yoshizaki, Madoka Takao, Toshitatsu Takao, Yoshinori Morita, Hiroshi Yokozaki, Yuzo Kodama
Clinical Endoscopy.2022; 55(1): 86. CrossRef
The importance of pH adjustment for preventing fibrin glue dissolution in the stomach: an in vitro study
Yoshitaka Takegawa, Toshitatsu Takao, Hiroya Sakaguchi, Tatsuya Nakai, Kazuhiro Takeo, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama
Scientific Reports.2022;[Epub] CrossRef
A Novel Self-Assembled Gel for Gastric Endoscopic Submucosal Dissection-Induced Ulcer: A Preclinical Study in a Porcine Model
Meng Li, Haifeng Jin, Changpei Shi, Bin Lyu, Xiao Ying, Yuan Shi
Frontiers in Pharmacology.2021;[Epub] CrossRef

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Endoscopic Characteristics of Rugal Hyperplasia and Related Acid Condition in Helicobacter pylori-Infected Stomach: Byung Chul Kim, Mi Ae Song, Sung Ho Kwon; Clin Endosc 2021;54(1):73-84. Published online December 15, 2020; DOI: https://doi.org/10.5946/ce.2020.020

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Background
/Aims: Rugal hyperplastic gastritis (RHG) is associated with Lauren’s diffuse-type gastric cancer (GC) and the accompanying active inflammation is linked to gastric hypoacidity. We tried to establish the steps for identifying high-risk GC patients.
Methods
We included 196 patients with confirmed Helicobacter pylori infection by rapid urease test during screening endoscopy for health check-up from January 2016 to September 2016; all patients underwent blood tests for pepsinogen I and II and fasting serum gastrin. We compared RHG findings with various other endoscopic mucosal images. We also evaluated the relationships between RHG and other mucosal aspects for a given acid status based on serological markers.
Results
Hypoacid and ultra-low-acid (67%) statuses were dominant, with only 18% hyperacid patients. RHG with high acid was related to a less atrophic body type (p=0.001), and RHG with ultra-low acid was associated with body xanthoma (p=0.029) and increased serum gastrin level (p=0.038). However, RHG’s influence on gastric acidity was only seen in closed-type endoscopic atrophic border (EAB), not in open type (p=0.001).
Conclusions
The majority of RHG patients had hypoacid status. RHG frequency showed no difference between closed and opentype EAB, but gastric acidity was influenced by RHG only in closed-type EAB.

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Cancer risk stratification system and classification of gastritis: Perspectives
Sergey M Kotelevets, Sergey A Chekh, Sergey Z Chukov
World Journal of Meta-Analysis.2023; 11(1): 18. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Giant Rugae in Helicobacter pylori-Infected Stomachs
Sun-Young Lee
Clinical Endoscopy.2021; 54(1): 1. CrossRef

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Clinicopathological Features of Small Bowel Tumors Diagnosed by Video Capsule Endoscopy and Balloon-Assisted Enteroscopy: A Single Center Experience: Ah Young Yoo, Beom Jae Lee, Won Shik Kim, Seong Min Kim, Seung Han Kim, Moon Kyung Joo, Hyo Jung Kim, Jong-Jae Park; Clin Endosc 2021;54(1):85-91. Published online August 31, 2020; DOI: https://doi.org/10.5946/ce.2020.047

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Background
/Aims: Small bowel malignancies often present a diagnostic challenge due to their relative rarity and nonspecific clinical symptoms. However, technical developments in endoscopic instruments, including video capsule endoscopy (VCE) and enteroscopy, have allowed for the visualization of the entire small bowel. This study aimed to investigate the clinicopathological features of small bowel malignant tumors diagnosed by VCE and double-balloon enteroscopy (DBE) in a single tertiary center.
Methods
We retrospectively analyzed VCE and DBE findings from Korea University Guro Hospital from January 2010 through September 2018.
Results
A total of 510 VCE and 126 DBE examinations were performed in 438 patients. Small bowel malignancies were diagnosed in 28 patients (15 males; mean age, 61.0 years; range, 42 to 81 years). Among them, 8 had lymphoma, 8 had primary adenocarcinoma, 7 had gastrointestinal stromal tumor (GIST) and 5 had metastatic cancer. Abdominal pain and obstructive symptoms were the most common findings in metastatic cancers (4/5, 80%). On the other hand, obscure gastrointestinal bleeding was the most common symptom of GIST (6/7, 85.7%) and adenocarcinoma (3/8, 37.5%).
Conclusions
Approximately 6% of the patients who underwent either VCE or DBE were diagnosed with small bowel malignancy. These findings demonstrated the different clinical characteristics among small bowel malignancies and merit further study.

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Prognostic factors for liver metastasis in patients with small intestinal stromal tumor: A retrospective analysis of surveillance, epidemiology, and end results
Luojie Liu, Rufa Zhang, Zhenguo Qiao, Ye Ye, Kaijian Xia, Yunfu Feng, Xiaodan Xu
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A practical approach for small bowel bleeding
Sung Eun Kim, Hyun Jin Kim, Myeongseok Koh, Min Cheol Kim, Joon Sung Kim, Ji Hyung Nam, Young Kwan Cho, A Reum Choe
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Clinicopathological characteristics and prognostic factors of small bowel lymphomas: a retrospective single-center study
Emanuel Dias, Renato Medas, Margarida Marques, Patrícia Andrade, Hélder Cardoso, Guilherme Macedo
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Ana-Maria Singeap, Catalin Sfarti, Horia Minea, Stefan Chiriac, Tudor Cuciureanu, Robert Nastasa, Carol Stanciu, Anca Trifan
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Symptoms Contributing to the Diagnosis of Small Bowel Tumors
Kozo Tsuruta, Hidetoshi Takedatsu, Shinichiro Yoshioka, Masahiro Yoshikai, Kensuke Tomiyasu, Masaru Morita, Kotaro Kuwaki, Keiichi Mitsuyama, Takumi Kawaguchi
Digestion.2023; 104(6): 430. CrossRef
Small bowel lymphoma: clinical update and challenges for the gastroenterologist
Priya Oka, Reena Sidhu
Current Opinion in Gastroenterology.2022; 38(3): 270. CrossRef
Indication, Location of the Lesion, Diagnostic Yield, and Therapeutic Yield of Double-Balloon Enteroscopy: Seventeen Years of Experience
Sang Pyo Lee, Hyun Joo Jang, Sea Hyub Kae, Jae Gon Lee, Ji Hye Kwon
Diagnostics.2022; 12(9): 2224. CrossRef
Minimally invasive surgery with adenocarcinoma of jejunum diagnosed pathologically before surgery: A case report
Sung Chul Lee
International Journal of Surgery Case Reports.2021; 79: 354. CrossRef
Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
Wonshik Kim, Beomjae Lee, Ahyoung Yoo, Seunghan Kim, Moonkyung Joo, Jong-Jae Park
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Small Bowel Malignancies in Patients Undergoing Capsule Endoscopy for Iron Deficiency Anemia
Su Hwan Kim, Ji Won Kim
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Colon Capsule Endoscopy: Indications, Findings, and Complications – Data from a Prospective German Colon Capsule Registry Trial (DEKOR): Johannes Hausmann, Andrea Tal, Artur Gomer, Michael Philipper, Gero Moog, Horst Hohn, Norbert Hesselbarth, Harald Plass, Jörg Albert, Fabian Finkelmeier; Clin Endosc 2021;54(1):92-99. Published online June 18, 2020; DOI: https://doi.org/10.5946/ce.2020.049

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Background
/Aims: Reliable and especially widely accepted preventive measures are crucial to further reduce the incidence of colorectal cancer (CRC). Colon capsule endoscopy (CCE) might increase the screening numbers among patients unable or unwilling to undergo conventional colonoscopy. This registry trial aimed to document and determine the CCE indications, findings, complications, and adverse events in outpatient practices and clinics throughout Germany.
Methods
Patients undergoing CCE between 2010 and 2015 were enrolled in this prospective multicenter registry trial at six German centers. Patient demographics, outcomes, and complications were evaluated.
Results
A total of 161 patients were included. Of the CCE evaluations, 111 (68.9%) were considered successful. Pathological findings in the colon (n=92, 60.1%) and in the remaining gastrointestinal tract (n=38, 24.8%) were recorded. The main finding was the presence of polyps (n=52, 32.3%). Furthermore, five carcinomas (3.1%) were detected and histologically confirmed later. Adequate bowel cleanliness was more likely to be achieved in the outpatient setting (p<0.0001). Interestingly, 85 patients (55.6%) chose to undergo CCE based on personal motivation.
Conclusions
CCE seems to be a reliable and safe endoscopic tool for screening for CRC and detecting other diseases. Its patient acceptance and feasibility seems to be high, especially in the outpatient setting.

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Advances in colon capsule endoscopy: a review of current applications and challenges
E. Gibbons, O. B. Kelly, B. Hall
Frontiers in Gastroenterology.2023;[Epub] CrossRef
Computer-Aided Diagnosis of Gastrointestinal Protruded Lesions Using Wireless Capsule Endoscopy: A Systematic Review and Diagnostic Test Accuracy Meta-Analysis
Hye Jin Kim, Eun Jeong Gong, Chang Seok Bang, Jae Jun Lee, Ki Tae Suk, Gwang Ho Baik
Journal of Personalized Medicine.2022; 12(4): 644. CrossRef
Colon Capsule Endoscopy in the Diagnosis of Colon Polyps: Who Needs a Colonoscopy?
Apostolos Koffas, Apostolis Papaefthymiou, Faidon-Marios Laskaratos, Andreas Kapsoritakis, Owen Epstein
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The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy
Benedicte Schelde-Olesen, Artur Nemeth, Gabriele Wurm Johansson, Ulrik Deding, Thomas Bjørsum-Meyer, Henrik Thorlacius, Gunnar Baatrup, Anastasios Koulaouzidis, Ervin Toth
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Colon Capsule Endoscopy: An Alternative for Conventional Colonoscopy?
Britt B.S.L. Houwen, Evelien Dekker
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Examination of Entire Gastrointestinal Tract: A Perspective of Mouth to Anus (M2A) Capsule Endoscopy
Ji Hyung Nam, Kwang Hoon Lee, Yun Jeong Lim
Diagnostics.2021; 11(8): 1367. CrossRef

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Survival Benefit of Intraductal Radiofrequency Ablation for Malignant Biliary Obstruction: A Systematic Review with Meta-Analysis: Byung Hyo Cha, Myoung-Jin Jang, Sang Hyub Lee; Clin Endosc 2021;54(1):100-106. Published online January 15, 2021; DOI: https://doi.org/10.5946/ce.2020.254

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Background
/Aims: Cholangiocarcinoma (CCA) is a rare but aggressive disease with a poor survival. Recent trials have shown improved survival with intraductal radiofrequency ablation (RFA) therapy. We performed a systematic review with meta-analysis to determine the survival benefit of endoscopic RFA for unresectable extrahepatic CCA with malignant biliary obstruction (MBO).
Methods
A systematic search from 1970 to 2020 was performed in MEDLINE, EMBASE, Cochrane Library, and ClinicalTrials. gov. We selected eligible studies reporting relative risks, hazard ratios (HRs), or odds ratios, adjusted by controlling for confounding factors of survival rate and stent patency duration, among patients with extrahepatic CCA with MBO treated with RFA with stent insertion or stent insertion only.
Results
A total of eight trials (three randomized and five nonrandomized) with a total of 420 patients were included in the metaanalysis. Pooled overall survival analysis favored RFA treatment with stent insertion (HR, 0.47; 95% confidence interval [CI], 0.34– 0.64; I²=47%; p=0.09); however, no significant difference was found in the duration of stent patency between the groups (HR, 0.79; 95% CI, 0.57–1.09; I²=7%; p=0.36).
Conclusions
RFA therapy with stent insertion may confer a survival benefit compared with stent insertion only in patients with CCA and MBO.

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Matheus de Oliveira Veras, Diogo Turiani Hourneaux de Moura, Thomas R. McCarty, Guilherme Henrique Peixoto de Oliveira, Rômulo Sérgio Araújo Gomes, Davi Lucena Landim, Felipe Giacobo Nunes, Tomazo Antônio Prince Franzini, Marcos Eduardo Lera dos Santos, W
Endoscopy International Open.2024; 12(01): E23. CrossRef
Reply to Chandrasekhara and Aggarwal
Matheus de Oliveira Veras, Diogo Turiani Hourneaux de Moura, Eduardo Guimarães Hourneaux de Moura
Endoscopy International Open.2024; 12(05): E640. CrossRef
Consensus statements on endoscopic radiofrequency ablation for malignant biliary strictures

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The Impact of Radiofrequency Ablation on Survival Outcomes and Stent Patency in Patients with Unresectable Cholangiocarcinoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Daniele Balducci, Michele Montori, Francesco Martini, Marco Valvano, Federico De Blasio, Maria Eva Argenziano, Giuseppe Tarantino, Antonio Benedetti, Emanuele Bendia, Marco Marzioni, Luca Maroni
Cancers.2024; 16(7): 1372. CrossRef
Impact of temperature-controlled endobiliary radiofrequency ablation for inoperable hilar cholangiocarcinoma: A propensity score–matched analysis
Il Sang Shin, Jong Ho Moon, Yun Nah Lee, Jun Ho Myeong, Tae Hoon Lee, Jae Kook Yang, Young Deok Cho, Sang-Heum Park
Endoscopy International Open.2024; 12(04): E535. CrossRef
Percutaneous endobiliary radiofrequency ablation and stent placement for unresectable malignant biliary obstruction: a propensity score matching retrospective study
Wei Cui, Jing-Zhi Huang, Qi Wang, Feng Shi, Qing Gou, Xiao-Ming Chen, Jing Zhang, Jia-Ping Li, Rongde Xu
BMC Gastroenterology.2024;[Epub] CrossRef
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Chao Zhang, Linzhong Zhu, Shousheng Tang, Jukun Wang, Yu Li, Xin Chen, Chunjing Bian, Dongbin Liu, Guokun Ao, Tao Luo
Cryobiology.2023; 111: 40. CrossRef
Efficacy and Safety of Radiofrequency Ablation Plus Stent Versus Stent-alone Treatments for Malignant Biliary Strictures
Hayat Khizar, Yufei Hu, Yanhua Wu, Kamran Ali, Junaid Iqbal, Muhammad Zulqarnain, Jianfeng Yang
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Development of novel biliary metal stent with coil-spring structure and its application in vivo swine biliary stricture model
In Rae Cho, Sang Hyub Lee, Jin Ho Choi, Namyoung Park, Min Woo Lee, Joo Seong Kim, Seok Jeong, Don Haeng Lee, Tae-Won Jeong, Byoung-Yun Ki, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
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In-stent radiofrequency ablation with uncovered metal stent placement for tumor ingrowth/overgrowth causing self-expandable metal stent occlusion in distal malignant biliary obstruction: multicenter propensity score–matched study
Namyoung Park, Min Kyu Jung, Eui Joo Kim, Woo Hyun Paik, Jae Hee Cho
Gastrointestinal Endoscopy.2023; 97(4): 694. CrossRef
ACG Clinical Guideline: Diagnosis and Management of Biliary Strictures
B. Joseph Elmunzer, Jennifer L. Maranki, Victoria Gómez, Anna Tavakkoli, Bryan G. Sauer, Berkeley N. Limketkai, Emily A. Brennan, Elaine M. Attridge, Tara J. Brigham, Andrew Y. Wang
American Journal of Gastroenterology.2023; 118(3): 405. CrossRef
Effect of radiofrequency ablation in addition to biliary stent on overall survival and stent patency in malignant biliary obstruction: an updated systematic review and meta-analysis
Zahid Ijaz Tarar, Umer Farooq, Mustafa Gandhi, Ghulam Ghous, Saad Saleem, Faisal Kamal, Zaid Imam, Laith Jamil
European Journal of Gastroenterology & Hepatology.2023; 35(6): 646. CrossRef
Impact of endobiliary radiofrequency ablation on survival of patients with unresectable cholangiocarcinoma: a narrative review
Elena Di Girolamo, Andrea Belli, Alessandro Ottaiano, Vincenza Granata, Valentina Borzillo, Luca Tarotto, Fabiana Tatangelo, Raffaele Palaia, Corrado Civiletti, Mauro Piccirillo, Valentina D’Angelo, Francesco Fiore, Pietro Marone, Guglielmo Nasti, Frances
Frontiers in Oncology.2023;[Epub] CrossRef
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Jana Jarosova, Lea Zarivnijova, Ivana Cibulkova, Jan Mares, Peter Macinga, Alzbeta Hujova, Premysl Falt, Ondrej Urban, Jan Hajer, Julius Spicak, Tomas Hucl
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Is endoscopic radiofrequency ablation plus stent placement superior to stent placement alone for the treatment of malignant biliary obstruction? A systematic review and meta-analysis
Chenming Liu, Jiaming Dong, Yuxing Liu, Siyuan Zhang, Ruanchang Chen, Haijun Tang
Journal of International Medical Research.2023;[Epub] CrossRef
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Abhishek Agnihotri, David E. Loren
Techniques and Innovations in Gastrointestinal Endoscopy.2022; 24(2): 200. CrossRef
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Yubeen Park, Dong-Sung Won, Ga-Hyun Bae, Dae Sung Ryu, Jeon Min Kang, Ji Won Kim, Song Hee Kim, Chu Hui Zeng, Wooram Park, Sang Soo Lee, Jung-Hoon Park
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David M. de Jong, Jeska A. Fritzsche, Amber S. Audhoe, Suzanne S. L. Yi, Marco J. Bruno, Rogier P. Voermans, Lydi M. J. W. van Driel
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Nadia V. Guardado, Kaysey Llorente, Benoit Blondeau
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Increased Risk of Pancreatitis after Endoscopic Retrograde Cholangiopancreatography Following a Positive Intraoperative Cholangiogram: A Single-Center Experience: Lalitha M. Sitaraman, Rita M. Knotts, Judith Kim, Srihari Mahadev, David S. Lee; Clin Endosc 2021;54(1):107-112. Published online July 15, 2020; DOI: https://doi.org/10.5946/ce.2020.025

Abstract PDF PubReader ePub

Background
/Aims: To determine if patients with a positive intraoperative cholangiogram (IOC) who undergo a subsequent endoscopic retrograde cholangiopancreatography (ERCP) have an increased risk of post-ERCP pancreatitis (PEP) compared to those who undergo ERCP directly for suspected common bile duct stones.
Methods
A retrospective case-control study was performed from 2010 to 2016. Cases included inpatients with a positive IOC at cholecystectomy who underwent subsequent ERCP. The control group included age-sex matched cohorts who underwent ERCP for choledocholithiasis. Multivariate logistic regression was used to assess the association between PEP and positive IOC, adjusting for matching variables and additional potential confounders.
Results
Of the 116 patients that met the inclusion criteria, there were 91 women (78%) in each group. Nine patients (7.8%) developed PEP in the IOC group, compared to 3 patients in the control group (2.6%). The use of pancreatic duct stents and rectal indomethacin was similar in both groups. After adjusting for age, sex, total bilirubin levels, and any stent placement, patients with a positive IOC had a significantly increased risk of PEP (odds ratio, 4.79; 95% confidence interval, 1.05–21.89; p<0.05).
Conclusions
In this single-center case-control study, there was a five-fold increased risk of PEP following a positive IOC compared to an age-sex matched cohort.

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Is Routine Intraoperative Cholangiogram Necessary in Patients With Mild Acute Biliary Pancreatitis Undergoing Index Admission Cholecystectomy?
Natalie M Quarmby, Minh Tu Vo, Sivakumar Gananadha
The American Surgeon™.2024;[Epub] CrossRef
Accuracy of intraoperative cholangiography and outcomes of ERCP in hospitalized patients with suspected choledocholithiasis
Masuma Syed, Sanghee K. Choi, Nikhil Thiruvengadam, Kendrick Che, Paul Leonor, Esther Wu, Maryam B. Tabrizi, Jeffrey Kim, Stephen Min, James Scheiman, John J. Kim
iGIE.2023; 2(2): 117. CrossRef
Endoscopic retrograde cholangiopancreatography is not necessary in all patients with an abnormal intraoperative cholangiogram
Andrawus Beany, Anandpreet S Ghataura, Shaanan T E Yong, Kee F Loo, Rajvinder Singh, Biju George, Mohamed A Chinnaratha
JGH Open.2023; 7(11): 797. CrossRef
Endoscopic retrograde cholangiopancreatography‐related adverse events in Korea: A nationwide assessment
Dong Kee Jang, Jungmee Kim, Chang Nyol Paik, Jung‐Wook Kim, Tae Hee Lee, Jae‐Young Jang, Seung Bae Yoon, Jun Kyu Lee
United European Gastroenterology Journal.2022; 10(1): 73. CrossRef

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Cyst Fluid Carcinoembryonic Antigen Level Difference between Mucinous Cystic Neoplasms and Intraductal Papillary Mucinous Neoplasms: Ibrahim Hakkı Köker, Nurcan Ünver, Fatma Ümit Malya, Ömer Uysal, Elmas Biberci Keskin, Hakan Şentürk; Clin Endosc 2021;54(1):113-121. Published online December 11, 2020; DOI: https://doi.org/10.5946/ce.2020.083

Abstract PDF PubReader ePub

Background
/Aims: The role of cyst fluid carcinoembryonic antigen (CEA) level in differentiating mucinous pancreatic cystic lesions (PCLs) is controversial. We investigated the role of cyst fluid CEA in differentiating low-risk (LR)-intraductal papillary mucinous neoplasms (IPMNs) from high-risk (HR)-IPMNs and LR-mucinous cystic neoplasms (MCNs).
Methods
This was a retrospective study of 466 patients with PCLs who underwent endoscopic ultrasound-guided fine-needleaspiration over a 7-year period. On histology, low-grade dysplasia and intermediate-grade dysplasia were considered LR, whereas high-grade dysplasia and invasive carcinoma were considered HR.
Results
Data on cyst fluid CEA levels were available for 50/102 mucinous PCLs with definitive diagnoses. The median CEA (range) levels were significantly higher in HR cysts than in LR cysts (2,624 [0.5–266,510] ng/mL vs. 100 [16.8–53,445]ng/mL, p=0.0012). The area under the receiver operating characteristic curve (AUROC) was 0.930 (95% confidence interval [CI], 0.5–0.8; p<0.001) for differentiating LR-IPMNs from LR-MCNs. The AUROC was 0.921 (95% CI, 0.823–1.000; p<0.001) for differentiating LR-IPMNs from HR-IPMNs. Both had a CEA cutoff level of >100ng/mL, with a negative predictive value (NPV) of 100%.
Conclusions
Cyst fluid CEA levels significantly vary between LR-IPMNs, LR-MCNs, and HR-IPMNs. A CEA cutoff level of >100ng/mL had a 100% NPV in differentiating LR-IPMNs from LR-MCNs and HR-IPMNs.

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Spectrum of MRI Features of Mucin-producing Neoplasms in the Abdomen and Pelvis
Pei-Kang Wei, Mamta Gupta, Leo L. Tsai, Karen S. Lee, Adrian M. Jaramillo, Martin P. Smith, Jordan D. LeGout, Anuradha S. Shenoy-Bhangle
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Ahmad Najdat Bazarbashi, Linda S. Lee
Clinical Endoscopy.2021; 54(1): 7. CrossRef
Deep Learning-Based Differentiation between Mucinous Cystic Neoplasm and Serous Cystic Neoplasm in the Pancreas Using Endoscopic Ultrasonography
Leang Sim Nguon, Kangwon Seo, Jung-Hyun Lim, Tae-Jun Song, Sung-Hyun Cho, Jin-Seok Park, Suhyun Park
Diagnostics.2021; 11(6): 1052. CrossRef

4,030 View
127 Download
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Esophageal Stricture Caused by the Ingestion of Undissolved Picosulfate Powder: Daehyun Kim, Byungha Cho, Jong Wook Choi, Ki Bae Kim, Seon Mee Park; Clin Endosc 2021;54(1):122-126. Published online March 16, 2020; DOI: https://doi.org/10.5946/ce.2019.206

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Picosulfate solution is widely used as a small volume bowel cleansing agent and is considered to be effective and relatively safe. A case of a 75-year-old woman ingested picosulfate powder and drank a small volume of water, subsequently experienced severe burning pain in the chest. Endoscopy was performed and showed a submucosal hemorrhage and exudative ulcers at the mid to lower esophagus. At 2 weeks, her symptoms improved with conservative treatment. However, liquid food dysphagia developed 11 weeks after ingestion. A follow-up endoscopy revealed multiple esophageal strictures, which were treated with a fully covered metal stent and esophageal balloon dilation. Consequently, the esophageal strictures improved after one year. As this case demonstrates, detailed information about picosulfate powder ingestion after dissolving it in more than 200 mL of water should be presented to patients to avoid esophageal injury.

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Citric acid/magnesium oxide/sodium picosulfate

Reactions Weekly.2021; 1868(1): 140. CrossRef

5,880 View
144 Download
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Hybrid Peroral Endoscopic Myotomy for Achalasia with Prior Treatment Failure: In Kyung Yoo, Abdullah OzgurYeniova, Joo Young Cho; Clin Endosc 2021;54(1):127-130. Published online April 2, 2020; DOI: https://doi.org/10.5946/ce.2020.013

Abstract PDF Supplementary Material PubReader ePub: Achalasia is a neurodegenerative motility disorder caused by enteric neuron damage in the lower esophageal sphincter. Peroral endoscopic myotomy (POEM) is a standard treatment method for achalasia. Previous treatment modalities may affect the outcome of POEM as they cause submucosal fibrosis. We report a new technique called “hybrid POEM” for the treatment of patients with achalasia who had been previously treated with pneumatic balloon dilatation. We performed two techniques of POEM simultaneously, the standard POEM for the upper part of the submucosal tunnel and open POEM for the stenotic part of the esophagogastric junction. We dissected the mucosa and submucosa, and performed myotomy simultaneously. We overcame submucosal fibrosis of the esophagogastric junction, which was caused by the previous hybrid POEM treatment. The risks of mucosal incision and technical challenge of submucosal tunneling for the fibrotic area may be reduced by hybrid POEM.

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Endoscopic Full-Thickness Resection for Gastric Subepithelial Lesions Arising from the Muscularis Propria: Ah Lon Jung, Sang Wook Park, Gun Young Hong, Hyeong Chul Moon, Seo Joon Eun; Clin Endosc 2021;54(1):131-135. Published online August 21, 2020; DOI: https://doi.org/10.5946/ce.2020.070

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Most cases of gastric subepithelial lesions follow a good clinical course; however, some lesions progress to malignant tumors, and treatment of tumors with a high risk of malignancy is essential. Surgical excision has been the primary treatment for tumors originating from the propria muscle layer, but it has the disadvantages of being invasive and causing postoperative functional abnormalities. With the development of endoscopic techniques and instruments, the role of endoscopic resection, which is a less invasive method for the removal of gastric subepithelial lesions, has been attracting attention. We performed an endoscopic full-thickness resection for 8 patients with gastric subepithelial lesions originating from the muscularis propria. No fatal complications occurred. Our findings suggest the need to develop various devices for resection and closure and to accumulate further experience through additional studies to prevent complications and specimen loss.

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A “One Accessory and One Guidewire-in-One Channel” Technique in a Patient with Billroth II Anastomosis: Kook Hyun Kim, Sung Bum Kim, Tae Nyeun Kim; Clin Endosc 2021;54(1):139-140. Published online July 7, 2020; DOI: https://doi.org/10.5946/ce.2020.087

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Differential Diagnosis for Chronic Diarrhea: Are Multiple Random Biopsies with Colonoscopy Mandatory?: Shin Hee Lee, Sang-Bum Kang; Clin Endosc 2021;54(1):141-142. Published online January 20, 2021; DOI: https://doi.org/10.5946/ce.2021.030

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