Clinical Endoscopy

Original Articles

A prospective study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures: Bhavik Bharat Shah, Gajanan Ashokrao Rodge, Usha Goenka, Shivaraj Afzalpurkar, Mahesh Kumar Goenka; Clin Endosc 2022;55(6):793-800. Published online April 4, 2022; DOI: https://doi.org/10.5946/ce.2021.211

Background
/Aims: Fully covered self-expanding metal stents (FCSEMSs) are a relatively novel option for treating painful main pancreatic duct refractory strictures in patients with chronic pancreatitis. Herein, we aimed to assess the efficacy, feasibility, and safety of FCSEMSs in this patient group.
Methods
This prospective single-center study included patients who underwent endoscopic retrograde pancreatography with FCSEMS placement. The primary endpoints were the technical and clinical success rates. A reduction in visual analog scale pain score of >50% compared with that before stent placement was defined as clinical success. Secondary endpoints were resolution of pancreatic strictures on fluoroscopy during endoscopic retrograde pancreatography and the development of stent-related adverse events.
Results
Thirty-six patients were included in the analysis. The technical success rate was 100% (n=36) and the clinical success rate was 86.1% (n=31). There was a significant increase in stricture diameter from 1.7 mm to 3.5 mm (p<0.001) after stent removal. The mean visual analog scale pain score showed statistically significant improvement. At 19 months of follow-up, 55.6% of the patients were asymptomatic. Stent migration (16.7%), intolerable abdominal pain (8.3%), development of de novo strictures (8.3%), and mild pancreatitis (2.8%) were the most common adverse events.
Conclusions
FCSEMS placement showed good technical and clinical success rates for achieving pain relief in patients with refractory main pancreatic duct strictures.

Citations

Citations to this article as recorded by

A review on pancreatic duct stents: materials and emerging trends
Huijuan Fan, Nan Li, Xingguang Zhang, Wei Xu, Wencheng Zhang, Yangjuan Ding, Lingjian Li, Taotao Liu, Shihai Xia
Biomedical Materials.2025; 20(3): 032004. CrossRef
Citric Acid Loaded Hydrogel-Coated Stent for Dissolving Pancreatic Duct Calculi
Jing Li, Yanwei Lv, Zheng Chen, Jiulong Zhao, Shige Wang
Gels.2024; 10(2): 125. CrossRef
Fully Covered Self-expandable Metallic Stents for Refractory Benign Pancreatic Duct Strictures: A Systematic Review and Meta-analysis
Gajanan Rodge, Suprabhat Giri, Kailash Kolhe, Shivaraj Afzalpurkar, Sidharth Harindranath, Sridhar Sundaram, Aditya Kale
Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2024; 34(5): 529. CrossRef
Self-expanding metallic stent for refractory pancreatic duct stricture in chronic pancreatitis: A prospective follow-up study
Praveer Rai, Pankaj Kumar, Ashok Kumar, Sana Asari, Kartik Agarwal, Mayank, Ravi V. Krishna Kishore, Prabhaker Mishra
Indian Journal of Gastroenterology.2023;[Epub] CrossRef
Quality of life after endoscopic procedures for chronic pancreatitis: A multicentre study
Mikael Parhiala, Camilla Nøjgaard, Andreas Bartholdy, Anne Waage, Povilas Ignatavičius, Trond Engjom, Georg Dimcevski, Ingrid Kvåle Nordaas, Evangelos Kalaitzakis, Asbjørn M. Drewes, Amer Hadi, Søren S. Olesen, Jakob L. Poulsen, Johanna Laukkarinen
United European Gastroenterology Journal.2023; 11(9): 884. CrossRef
Pancreatic duct stents
Jin Hui Yi, Zhao Shen Li, Liang Hao Hu
Journal of Digestive Diseases.2022; 23(12): 675. CrossRef

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Mucosal Changes in the Small Intestines in Portal Hypertension: First Study Using the Pillcam SB3 Capsule Endoscopy System: Mahesh Kumar Goenka, Bhavik Bharat Shah, Vijay Kumar Rai, Surabhi Jajodia, Usha Goenka; Clin Endosc 2018;51(6):563-569. Published online October 5, 2018; DOI: https://doi.org/10.5946/ce.2018.041

Abstract PDF PubReader ePub

Background
/Aims: To evaluate patients with portal hypertension (PH) of varied etiologies for portal hypertensive enteropathy (PHE) using the PillCam SB3 capsule endoscopy (CE) system.
Methods
Consecutive patients with PH presenting with unexplained anemia and/or occult gastrointestinal bleeding were evaluated using the PillCam SB3 CE system. Abnormal findings were categorized as vascular or non-vascular. The patients with ongoing bleeding caused by PHE were treated. The correlation of the CE scores of PHE with the clinical, laboratory, and endoscopic features was determined.
Results
Of the 43 patients included in the study, 41 (95.3%) showed PHE findings. These included varices (67.4%), red spots (60.5%), erythema (44.2%), villous edema (46.5%), telangiectasia (16.3%), and polyps (16.3%). The CE scores varied from 0 to 8 (mean±standard deviation, 4.09±1.8). Five patients (11.6%) showed evidence of ongoing or recent bleeding due to PHE. Three of these five patients underwent endotherapy, and one patient underwent radiological coil placement.
Conclusions
The PillCam SB3 CE system revealed a high prevalence of PHE in the patients with PH. Using this system, evidence of bleeding due to PHE was found in a small but definite proportion of the patients.

Citations

Citations to this article as recorded by

Capsule endoscopy for small bowel bleed: Current update
Uday C. Ghoshal, Akash Roy, Mahesh K. Goenka
Indian Journal of Gastroenterology.2024; 43(5): 896. CrossRef
Diagnosis and management of ectopic varices in portal hypertension
Thomas H Tranah, Jeremy S Nayagam, Stephen Gregory, Sarah Hughes, David Patch, Dhiraj Tripathi, Debbie L Shawcross, Deepak Joshi
The Lancet Gastroenterology & Hepatology.2023; 8(11): 1046. CrossRef
The Role of Video Capsule Endoscopy in Liver Disease
Alexander Ross Robertson, Anastasios Koulaouzidis, Emanuele Rondonotti, Mauro Bruno, Marco Pennazio
Gastrointestinal Endoscopy Clinics of North America.2021; 31(2): 363. CrossRef
Role of Video Capsule in Small Bowel Bleeding
Richard M. Wu, Laurel R. Fisher
Gastrointestinal Endoscopy Clinics of North America.2021; 31(2): 277. CrossRef
The Usefulness of New-Generation Capsule Endoscopy in Patients with Portal Hypertensive Enteropathy
Seung-Joo Nam, Ji Hyun Kim, Sung Chul Park
Clinical Endoscopy.2018; 51(6): 505. CrossRef

7,834 View
139 Download
4 Web of Science
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