Schwannomas of the gastrointestinal (GI) tract are rare subepithelial tumors comprising approximately 3.3% to 12.8% of all mesenchymal tumors of the GI tract. On endoscopic ultrasound (EUS) they are seen as hypoechoic tumors arising most commonly from the 4th proper muscle layer. Although EUS helps to distinguish tumor characteristics, tissue sampling is required for differentiation with other more common tumors such as GI stromal tumors. Both EUS-guided fine needle aspiration and EUS-guided trucut biopsy (EUS-TCB) can be used for tissue sampling. However, only EUS-TCB allows core biopsy and a high yield of immunohistochemical staining. We report a case of a gastric schwannoma diagnosed by EUS-TCB.

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• Differential diagnosis of submucosal gastric tumors: gastric schwannomas misdiagnosed as GISTs
  Mutlu Unver, Suleyman Cağlar Ertekin, Eyüp Kebapcı, Mustafa Olmez, Erhan Ergin, Safak Ozturk, Erkan Sahin, Ragıp Ortac
  Journal of Surgical Case Reports.2024;[Epub]     CrossRef
• What About Gastric Schwannoma? A Review Article
  Sara Lauricella, Sergio Valeri, Gianluca Mascianà, Ida Francesca Gallo, Erica Mazzotta, Chiara Pagnoni, Saponaro Costanza, Lorenza Falcone, Domenico Benvenuto, Marco Caricato, Gabriella Teresa Capolupo
  Journal of Gastrointestinal Cancer.2021; 52(1): 57.     CrossRef
• Intramuscular ancient schwannoma of the axillary nerve
  Vishali Moond, Preeti Diwaker, Reshma Golamari, Rohit Jain
  BMJ Case Reports.2021; 14(5): e239445.     CrossRef
• Gastric schwannoma: a case report and literature review
  Changsheng Pu, Keming Zhang
  Journal of International Medical Research.2020;[Epub]     CrossRef
• Gastric Schwannomas Misdiagnosed as GIST: A Comparative Study of Clinic Strategies Based on Membrane Marker Detection
  Quanyong Cheng, Kun Zhao, Jing Wang, Yu Guo, Hui Pang
  Journal of Cancer Research Updates.2020; 9(1): 82.     CrossRef
• Clinical characteristics and surgical treatment of schwannomas of the esophagus and stomach: A case series and systematic review
  Jesús Morales-Maza, Francisco Ulises Pastor-Sifuentes, Germán E Sánchez-Morales, Emilio Sanchez-Garcia Ramos, Oscar Santes, Uriel Clemente-Gutiérrez, Adriana Simoneta Pimienta-Ibarra, Heriberto Medina-Franco
  World Journal of Gastrointestinal Oncology.2019; 11(9): 750.     CrossRef
• Axillary schwannoma, preoperative diagnosis on a tru-cut biopsy: Case report and literature review
  Hager Aref, Georges A. Abizeid
  International Journal of Surgery Case Reports.2018; 52: 49.     CrossRef
• Spectral Computed Tomography Imaging of Gastric Schwannoma and Gastric Stromal Tumor
  Jianli Liu, Yanjun Chai, Junlin Zhou, Chi Dong, Wenjuan Zhang, Bin Liu
  Journal of Computer Assisted Tomography.2017; 41(3): 417.     CrossRef
• Role of endoscopic ultrasound and endoscopic resection for the treatment of gastric schwannoma
  Jinlong Hu, Xiang Liu, Nan Ge, Sheng Wang, Jintao Guo, Guoxin Wang, Siyu Sun
  Medicine.2017; 96(25): e7175.     CrossRef
• Two Synchronous Colonic Adenocarcinomas, a Gastric Schwannoma and a Mucinous Neoplasm of the Appendix: a Case Report
  Diogo Sousa, Miguel Allen, Alda Pinto, Andreia Ferreira, Ana Cruz, Diogo Marinho, Pierpaolo Cusati, José Augusto Martins
  Journal of Gastrointestinal Cancer.2015; 46(3): 304.     CrossRef
• Benign Gastric Schwannoma: How Long Should We Follow Up to Monitor the Recurrence? A Case Report and Comprehensive Review of Literature of 137 Cases
  Xiafei Hong, Wenming Wu, Mengyi Wang, Quan Liao, Yupei Zhao
  International Surgery.2015; 100(4): 744.     CrossRef

Hypopharyngeal cancers are often diagnosed at an advanced stage and have a poor prognosis. Even when they are diagnosed at an operable stage, surgery often results in substantial morbidity and decreased patients' quality of life. Although the endoscopic diagnosis of early hypopharyngeal cancer is difficult, recent developments in advanced imaging endoscopy have enabled easier diagnosis of these lesions. Endoscopic resection of early hypopharyngeal cancer is a potential minimally invasive treatment that can preserve the function and quality of life of patients. Reports of this procedure are limited, however. We report a case of hypopharygeal cancer treated with endoscopic resection.

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  Ce Li, Shuai Chen, Wenming Jia, Wenming Li, Dongmin Wei, Shengda Cao, Ye Qian, Rui Guan, Heng Liu, Dapeng Lei
  Frontiers in Immunology.2022;[Epub]     CrossRef
• Endoscopic resection for superficial hypopharyngeal/laryngeal cancer and clinical pathway options
  Wei‐Chen Huang, Li‐Hsiang Cheng, Tien‐Yu Huang, Yu‐Lueng Shih, Wei‐Kuo Chang, Tsai‐Yuan Hsieh, Peng‐Jen Chen
  Advances in Digestive Medicine.2019; 6(3): 123.     CrossRef
• MG132 reverse the malignant characteristics of hypopharyngeal cancer
  JUKE MA, LIANG YU, JIAJUN TIAN, YAKUI MU, ZHENGHUA LV, JIDONG ZOU, JIANFENG LI, HAIBO WANG, WEI XU
  Molecular Medicine Reports.2014; 9(6): 2587.     CrossRef