Clinical Endoscopy

Endoscopic Factors that Can Predict Histological Ulcerations in Early Gastric Cancers: Jaesin Lee, Byung-Wook Kim, Cheal Wung Huh, Joon Sung Kim, Lee-So Maeng; Clin Endosc 2020;53(3):328-333. Published online January 7, 2020; DOI: https://doi.org/10.5946/ce.2019.133

Background
/Aims: Predicting histological ulceration in early gastric cancer (EGC) during endoscopic examination is crucial for endoscopists deciding on the treatment modality. The aim of this study was to investigate the endoscopic factors that can predict histological ulcerations in EGCs.
Methods
We retrospectively analyzed patients who underwent endoscopic submucosal dissection (ESD) for EGC. Clinical features and endoscopic characteristics of EGC such as location, histological differentiation, longest diameter, tumor morphology, mucosal break, converging fold, color change, and surface irregularity were reviewed. Histological ulceration was defined based on ESD specimens.
Results
A total of 633 EGC lesions from 613 patients were included and histological ulcerations were found in 90 lesions (14.2%). Presence of converging folds, tumor morphology, and color changes on endoscopic examination were related to histological ulceration in the univariate analysis and converging folds along with color changes were statistically significant factors in the multivariate analysis. Kaplan–Meier analysis showed that patients with histological ulcerations in EGCs tended to have higher marginal recurrence rates.
Conclusions
Mucosal breaks are not equivalent to histological ulcerations. Rather, the existence of converging folds and color changes during endoscopic examination suggest histological ulcerations. Endoscopists should consider these factors when they decide the treatment modality for EGCs.

Citations

Citations to this article as recorded by

Clinical Impact of Proton Pump Inhibitor and Potassium-Competitive Acid Blocker for Predicting the Curability of Endoscopic Resection in Ulcerative Early Gastric Cancer
Konomu Uno, Takaya Shimura, Shingo Inaguma, Keita Kuroyanagi, Ruriko Nishigaki, Takuya Kanno, Makiko Sasaki, Shigeki Fukusada, Naomi Sugimura, Yusuke Mizuno, Takayuki Nukui, Yuki Kojima, Mamoru Tanaka, Keiji Ozeki, Eiji Kubota, Satoru Takahashi, Hiromi Ka
Digestion.2024; 105(3): 192. CrossRef
Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer
Sung Eun Oh, Soomin Ahn, Kyoung-Mee Kim, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Ji Yeong An
Gastric Cancer.2024; 27(4): 850. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef
Construction and analysis of an ulcer risk prediction model after endoscopic submucosal dissection for early gastric cancer
San-Dong Gong, Huan Li, Yi-Bin Xie, Xiao-Hui Wang
World Journal of Gastrointestinal Oncology.2022; 14(9): 1823. CrossRef
Long‑term outcome of the endoscopic submucosal dissection of early gastric cancer: A comparison between patients with and without liver cirrhosis
Seung Kim, Moon Joo, Ah-Young Yoo, Seong Kim, Won Kim, Beom Lee, Jong Park, Hoon Chun, Sang Lee
Oncology Letters.2022;[Epub] CrossRef
Discrepancy between endoscopic and pathological ulcerative findings in clinical intramucosal early gastric cancer
Yohei Yabuuchi, Kohei Takizawa, Naomi Kakushima, Noboru Kawata, Masao Yoshida, Yoichi Yamamoto, Yoshihiro Kishida, Sayo Ito, Kenichiro Imai, Hirotoshi Ishiwatari, Kinichi Hotta, Hiroyuki Matsubayashi, Etsuro Bando, Masanori Terashima, Takashi Sugino, Hiro
Gastric Cancer.2021; 24(3): 691. CrossRef
What is the Most Precise Endoscopic Finding for Predicting the Clinicopathological Behaviors in Ulcerative Early Gastric Cancer?
Youngdae Kim
Clinical Endoscopy.2020; 53(3): 249. CrossRef

8,676 View
170 Download
8 Web of Science
8 Crossref

Delayed Duodenal Perforation of an Endoscopic Mucosal Resection- Induced Ulcer due to a Foreign Body: Tae-Geun Gweon, Cheal Wung Huh, Byung-Wook Kim; Clin Endosc 2019;52(6):624-625. Published online July 8, 2019; DOI: https://doi.org/10.5946/ce.2019.083

PDF PubReader ePub

5,428 View
100 Download

Clinical Significance of Risk Factors for Asymptomatic Peptic Ulcer Disease: Cheal Wung Huh, Byung-Wook Kim; Clin Endosc 2017;50(6):514-515. Published online November 30, 2017; DOI: https://doi.org/10.5946/ce.2017.159

PDF PubReader ePub

Citations

Citations to this article as recorded by

Peptic ulcer disease
Shumma Raja
InnovAiT: Education and inspiration for general practice.2025; 18(5): 259. CrossRef
Peptic ulcer
Isabel Laucirica, Pilar Garcia Iglesias, Xavier Calvet
Medicina Clínica (English Edition).2023; 161(6): 260. CrossRef
Impact of peptic ulcer disease on the quality of life: A Cross Sectional Study
Sadeel A. Shanshal, Ali Saleh Noori, Jaafar Atheer Ghazi, Abdullah Tahseen Dahham, Abdulrahman Samer Mohamed Saleh, Harith Kh. Al-Qazaz
Research Journal of Pharmacy and Technology.2022; : 3267. CrossRef
The characteristics of 83 giant peptic ulcers in Chinese children: Evaluation and follow-up
Zifei Tang, Jieru Shi, Min Ji, Peng Shi, Zhiheng Huang, Ying Huang
Saudi Journal of Gastroenterology.2018; 24(6): 360. CrossRef

7,878 View
169 Download
2 Web of Science
4 Crossref

Search