Clinical Endoscopy

Review

Image-enhanced endoscopy in upper gastrointestinal disease: focusing on texture and color enhancement imaging and red dichromatic imaging: Jae Yong Park; Clin Endosc 2025;58(2):163-180. Published online November 6, 2024; DOI: https://doi.org/10.5946/ce.2024.159

Endoscopic examination plays a crucial role in the diagnosis of upper gastrointestinal (UGI) tract diseases. Despite advancements in endoscopic imaging, the detection of subtle early cancers and premalignant lesions using white-light imaging alone remains challenging. This review discusses two novel image-enhanced endoscopy (IEE) techniques–texture and color enhancement imaging (TXI) and red dichromatic imaging (RDI)–and their potential applications in UGI diseases. TXI enhances texture, brightness, and color tone, which improves the visibility of mucosal irregularities and facilitates earlier detection of neoplastic lesions. Studies have suggested that TXI enhances the color differences between lesions and the surrounding mucosa and improves the visibility of the lesion. TXI aids in the diagnosis of various UGI diseases, including early gastric cancer, esophageal cancer, premalignant conditions such as atrophic gastritis and Barrett’s esophagus, and duodenal tumors. RDI utilizes specific wavelengths to enhance the visualization of deep blood vessels or bleeding points, aiding in the rapid and accurate identification of bleeding sources during endoscopic procedures. Although promising, TXI and RDI require further large-scale studies across diverse populations to establish their clinical utility, diagnostic performance, and cost-effectiveness before integration into the guidelines. Standardized training is also required for effective utilization. Overall, these IEE techniques has the potential to improve the diagnosis and management of UGI.

Citations

Citations to this article as recorded by

Navigating the Treatment Landscape for Widespread Superficial Esophageal Squamous Cell Neoplasia
Moon Won Lee, Gwang Ha Kim
Gut and Liver.2025; 19(3): 305. CrossRef

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Case Report

Simultaneous Esophageal and Gastric Metastases from Lung Cancer: Jae Yong Park, Seung Wook Hong, Joo Young Lee, Ji Hye Kim, Jin Woo Kang, Hyun Woo Lee, Jong Pil Im; Clin Endosc 2015;48(4):332-335. Published online July 24, 2015; DOI: https://doi.org/10.5946/ce.2015.48.4.332

Abstract PDF PubReader ePub

We report of a patient with metastatic adenocarcinoma of the esophagus and stomach from lung cancer. The patient was a 68-year-old man receiving radiotherapy and chemotherapy for stage IV lung cancer, without metastases to the gastrointestinal (GI) tract at the time of the initial diagnosis. During the treatment period, dysphagia and melena newly developed. Upper GI endoscopy revealed geographic erosion at the distal esophagus and multiple volcano-shaped ulcers on the stomach body. Endoscopic biopsy was performed for each lesion. To determine whether the lesions were primary esophageal and gastric cancer masses or metastases from the lung cancer, histopathological testing including immunohistochemical staining was performed, and metastasis from lung cancer was confirmed. The disease progressed despite chemotherapy, and the patient died 5 months after the diagnosis of lung cancer. This is a case report of metastatic adenocarcinoma in the esophagus and stomach, which are very rare sites of spread for lung cancer.

Citations

Citations to this article as recorded by

Gastric Metastasis of Primary Lung Cancer: Case Report and Systematic Review With Pooled Analysis
Dong Tang, Jianjian Lv, Zhijing Liu, Shuhui Zhan, Yuqiang Gao
Frontiers in Oncology.2022;[Epub] CrossRef
Lung cancer metastasis to the gastrointestinal system: An enigmatic occurrence
Kanthi Rekha Badipatla, Niharika Yadavalli, Trupti Vakde, Masooma Niazi, Harish K Patel
World Journal of Gastrointestinal Oncology.2017; 9(3): 129. CrossRef

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56 Download
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