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Original Article
Optimal Methods for the Management of Iatrogenic Colonoscopic Perforation
Dae Kyu Shin, Sun Young Shin, Chi Young Park, Sun Mi Jin, Yang Hyun Cho, Won Hee Kim, Chang-Il Kwon, Kwang Hyun Ko, Ki Baik Hahm, Pil Won Park, Jong Woo Kim, Sung Pyo Hong
Clin Endosc 2016;49(3):282-288.   Published online February 18, 2016
DOI: https://doi.org/10.5946/ce.2015.046
AbstractAbstract PDFPubReaderePub
Background
/Aims: Colonoscopic perforations have been managed with exploratory laparotomy, and have resulted in some morbidity and mortality. Recently, laparoscopic surgery is commonly performed for this purpose. The aim of this study was to compare the outcomes of several management strategies for iatrogenic colonoscopic perforations.
Methods
We retrospectively reviewed the medical records of patients who had been treated for colonoscopic perforation between January 2004 and April 2013 at CHA Bundang Medical Center in Korea.
Results
A total of 41 patients with colonoscopic perforation were enrolled. Twenty patients underwent conservative management with a success rate of 90%. Surgical management was performed in 23 patients including two patients who were converted to surgical management after the failure of the initial conservative management. Among 14 patients who underwent surgery at 8 hours after the perforation, there was no considerable difference in adverse outcomes between the laparotomy group and the laparoscopic surgery group. The medical costs and claim rate were 1.45 and 1.87 times greater in the exploratory laparotomy group, respectively.
Conclusions
Conservative management of colonoscopic perforation could be an option for patients without overt symptoms of peritonitis or with a small defect size. If surgical management is required, laparoscopic surgery may be considered as the initial procedure even with a delayed diagnosis.

Citations

Citations to this article as recorded by  
  • Surgical repair of endoscopy-induced colonic perforations: a case-matched study of short-term morbidity and mortality
    Fady DANIEL, Suha JABAK, Mohammad HOSNI, Hani TAMIM, Aurelie MAILHAC, Ayman ALRAZIM, Noura AL-ALI, Robert CHURCH, Mohammad KHALIFE, Shafik SIDANI, Faek JAMALI
    Minerva Surgery.2024;[Epub]     CrossRef
  • Laparoscopic versus open surgery for colonoscopic perforation: A systematic review and meta-analysis
    Wu Zhong, Chuanyuan Liu, Chuanfa Fang, Lei Zhang, Xianping He, Weiquan Zhu, Xueyun Guan
    Medicine.2023; 102(24): e34057.     CrossRef
  • Elastography for Pediatric Chronic Liver Disease
    Giovanna Ferraioli, Richard G. Barr, Jonathan R. Dillman
    Journal of Ultrasound in Medicine.2021; 40(5): 909.     CrossRef
  • Clinical outcomes of laparoscopic versus open surgery for repairing colonoscopic perforation: a multicenter study
    Jae Seok Lee, Jeong Yeon Kim, Byung Mo Kang, Sang Nam Yoon, Jun Ho Park, Bo Young Oh, Jong Wan Kim
    Surgery Today.2021; 51(2): 285.     CrossRef
  • The analysis of outcomes of surgical management for colonoscopic perforations: A 16-years experiences at a single institution
    Dae Ro Lim, Jung Kul Kuk, Taehyung Kim, Eung Jin Shin
    Asian Journal of Surgery.2020; 43(5): 577.     CrossRef
  • Multicenter retrospective evaluation of ileocecocolic perforations associated with diagnostic lower gastrointestinal endoscopy in dogs and cats
    Vanessa L. Woolhead, Jacqueline C. Whittemore, Sarah A. Stewart
    Journal of Veterinary Internal Medicine.2020; 34(2): 684.     CrossRef
  • Endoscopic Management of the Ascending Colon Perforation Secondary to a Rare-Earth Magnets Ingestion in a Pediatric Patient
    Sandra Mabel Camacho-Gomez, James Meredith Noel, Robert Adam Noel
    ACG Case Reports Journal.2020; 7(8): e00436.     CrossRef
  • Pseudo‐obstruction But a Real Perforation

    AORN Journal.2019; 109(1): 142.     CrossRef
  • Treatment of colonoscopic perforation: outcomes from a major single tertiary institution
    Carolyn R. Chew, Justin M. C. Yeung, Ian G. Faragher
    ANZ Journal of Surgery.2019; 89(5): 546.     CrossRef
  • Management of colonoscopic perforations: A systematic review
    Alexander T. Hawkins, Kenneth W. Sharp, Molly M. Ford, Roberta L. Muldoon, M. Benjamin Hopkins, Timothy M. Geiger
    The American Journal of Surgery.2018; 215(4): 712.     CrossRef
  • 2017 WSES guidelines for the management of iatrogenic colonoscopy perforation
    Nicola de’Angelis, Salomone Di Saverio, Osvaldo Chiara, Massimo Sartelli, Aleix Martínez-Pérez, Franca Patrizi, Dieter G. Weber, Luca Ansaloni, Walter Biffl, Offir Ben-Ishay, Miklosh Bala, Francesco Brunetti, Federica Gaiani, Solafah Abdalla, Aurelien Ami
    World Journal of Emergency Surgery.2018;[Epub]     CrossRef
  • Management Outcomes of Colonoscopic Perforations Are Affected by the General Condition of the Patients
    Jae Ho Park, Kyung Jong Kim
    Annals of Coloproctology.2018; 34(1): 16.     CrossRef
  • Abdominal Sepsis: An Update
    Mircea Gabriel Mureșan, Ioan Alexandru Balmoș, Iudita Badea, Ario Santini
    The Journal of Critical Care Medicine.2018; 4(4): 120.     CrossRef
  • Laparoscopic vs. open surgery for the treatment of iatrogenic colonoscopic perforations: a systematic review and meta-analysis
    Aleix Martínez-Pérez, Nicola de’Angelis, Francesco Brunetti, Yann Le Baleur, Carmen Payá-Llorente, Riccardo Memeo, Federica Gaiani, Marco Manfredi, Paschalis Gavriilidis, Giorgio Nervi, Federico Coccolini, Aurelien Amiot, Iradj Sobhani, Fausto Catena, Gia
    World Journal of Emergency Surgery.2017;[Epub]     CrossRef
  • Urinary Bladder Injury During Colonoscopy Without Colon Perforation
    Jung Wook Suh, Jun Won Min, Hwan Namgung, Dong-Guk Park
    Annals of Coloproctology.2017; 33(3): 112.     CrossRef
  • The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections
    Massimo Sartelli, Alain Chichom-Mefire, Francesco M. Labricciosa, Timothy Hardcastle, Fikri M. Abu-Zidan, Abdulrashid K. Adesunkanmi, Luca Ansaloni, Miklosh Bala, Zsolt J. Balogh, Marcelo A. Beltrán, Offir Ben-Ishay, Walter L. Biffl, Arianna Birindelli, M
    World Journal of Emergency Surgery.2017;[Epub]     CrossRef
  • How Should We Manage Iatrogenic Perforation Caused by Colonoscopy?
    Eun Sun Kim
    Clinical Endoscopy.2016; 49(3): 214.     CrossRef
  • 8,306 View
  • 151 Download
  • 20 Web of Science
  • 17 Crossref
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Review
Image Quality Analysis of Various Gastrointestinal Endoscopes: Why Image Quality Is a Prerequisite for Proper Diagnostic and Therapeutic Endoscopy
Weon Jin Ko, Pyeong An, Kwang Hyun Ko, Ki Baik Hahm, Sung Pyo Hong, Joo Young Cho
Clin Endosc 2015;48(5):374-379.   Published online September 30, 2015
DOI: https://doi.org/10.5946/ce.2015.48.5.374
AbstractAbstract PDFPubReaderePub

Arising from human curiosity in terms of the desire to look within the human body, endoscopy has undergone significant advances in modern medicine. Direct visualization of the gastrointestinal (GI) tract by traditional endoscopy was first introduced over 50 years ago, after which fairly rapid advancement from rigid esophagogastric scopes to flexible scopes and high definition videoscopes has occurred. In an effort towards early detection of precancerous lesions in the GI tract, several high-technology imaging scopes have been developed, including narrow band imaging, autofocus imaging, magnified endoscopy, and confocal microendoscopy. However, these modern developments have resulted in fundamental imaging technology being skewed towards red-green-blue and this technology has obscured the advantages of other endoscope techniques. In this review article, we have described the importance of image quality analysis using a survey to consider the diversity of endoscope system selection in order to better achieve diagnostic and therapeutic goals. The ultimate aims can be achieved through the adoption of modern endoscopy systems that obtain high image quality.

Citations

Citations to this article as recorded by  
  • Colonoscopy Quality, Innovation, and the Assessment of New Technology
    Sanjay R.V. Gadi, Sriya S. Muralidharan, Jeremy R. Glissen Brown
    Techniques and Innovations in Gastrointestinal Endoscopy.2024; 26(2): 177.     CrossRef
  • Endoscopy image enhancement method by generalized imaging defect models based adversarial training
    Wenjie Li, Jingfan Fan, Yating Li, Pengcheng Hao, Yucong Lin, Tianyu Fu, Danni Ai, Hong Song, Jian Yang
    Physics in Medicine & Biology.2022; 67(9): 095016.     CrossRef
  • Reduced detection rate of artificial intelligence in images obtained from untrained endoscope models and improvement using domain adaptation algorithm
    Junseok Park, Youngbae Hwang, Hyun Gun Kim, Joon Seong Lee, Jin-Oh Kim, Tae Hee Lee, Seong Ran Jeon, Su Jin Hong, Bong Min Ko, Seokmin Kim
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Diagnosis of Early Gastric Cancer Using Image-enhanced Endoscopy
    Weon Jin Ko
    The Korean Journal of Medicine.2017; 92(3): 264.     CrossRef
  • 8,233 View
  • 104 Download
  • 5 Web of Science
  • 4 Crossref
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Case Report
Extragastroesophageal Malignancy-Associated Secondary Achalasia: A Rare Association of Pancreatic Cancer Rendering Alarm Manifestation
Hong Min Kim, Ji Min Chu, Won Hee Kim, Sung Pyo Hong, Ki Baik Hahm, Kwang Hyun Ko
Clin Endosc 2015;48(4):328-331.   Published online July 24, 2015
DOI: https://doi.org/10.5946/ce.2015.48.4.328
AbstractAbstract PDFPubReaderePub

Secondary achalasia or pseudoachalasia is a rare esophageal motor abnormality, which mimics primary achalasia; it is not easily distinguishable from idiopathic achalasia by manometry, radiological examination, or endoscopy. Although the majority of reported pseudoachalasia cases are associated with neoplasms at or near the esophagogastric (EG) junction, other neoplastic processes or even chronic illnesses such as rheumatoid arthritis can lead to the development of pseudoachalasia, for example, mediastinal masses, gastrointestinal (GI) tumors of the liver and biliary tract, and non-GI malignancies. Therefore, even if a patient presents with the typical findings of achalasia, we should be alert to the possibility of other GI malignancies besides EG tumors. For instance, pancreatic cancer was found in the case reported here; only four such cases have been reported in the literature. A 47-year-old man was admitted to our center with a 3-month history of dysphagia. His endoscopic and esophageal manometric findings were compatible with primary achalasia. However, unresponsiveness to diverse conventional achalasia treatments led us to suspect secondary achalasia. An active search led to a diagnosis of pancreatic mucinous cystadenocarcinoma invading the gastric fundus and EG junction. This rare case of pseudoachalasia caused by pancreatic carcinoma emphasizes the need for suspecting GI malignancies other than EG tumors in patients refractory to conventional achalasia treatment.

Citations

Citations to this article as recorded by  
  • Delayed Presentation of Malignancy-Associated Pseudoachalasia of the Gastric Cardia
    Clive J Miranda, Farhan Azad, Ross R Moyer, Sasikanth N Ravi, Gina M Sparacino
    Cureus.2024;[Epub]     CrossRef
  • Is it necessary to perform a morphological assessment for an esophageal motility disorder? A retrospective descriptive study
    Sofya Latrache, Chloe Melchior, Charlotte Desprez, Sabrina Sidali, Julien Recton, Olivier Touchais, Elise van der Eecken, Fabien Wuestenberghs, Cloe Charpentier, Anne Marie Leroi, Guillaume Gourcerol
    Clinics and Research in Hepatology and Gastroenterology.2021; 45(6): 101633.     CrossRef
  • When a Late Metastasis Is Hard to Swallow
    Catarina Negrão, Rita Sismeiro, Margarida Monteiro, Filipa G Pereira, Marta Jonet
    Cureus.2021;[Epub]     CrossRef
  • Development of pseudoachalasia following magnetic sphincter augmentation (MSA) with restoration of peristalsis after endoscopic dilation
    Katrin Schwameis, Shahin Ayazi, Ali H. Zaidi, Toshitaka Hoppo, Blair A. Jobe
    Clinical Journal of Gastroenterology.2020; 13(5): 697.     CrossRef
  • Burkitt’s Lymphoma of the Gastrohepatic Omentum: A Malignant Presentation of Pseudoachalasia
    Eric Omar Then, Andrew Ofosu, Prashanth Rawla, Tagore Sunkara, Sriharsha Dadana, Andrea Culliford, Vinaya Gaduputi
    Case Reports in Gastrointestinal Medicine.2019; 2019: 1.     CrossRef
  • 7,199 View
  • 57 Download
  • 6 Web of Science
  • 5 Crossref
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Original Article
Endoscopic Submucosal Dissection Using a Novel Versatile Knife: An Animal Feasibility Study (with Video)
Chang-Il Kwon, Gwangil Kim, Il-Kwun Chung, Won Hee Kim, Kwang Hyun Ko, Sung Pyo Hong, Seok Jeong, Don Haeng Lee
Clin Endosc 2014;47(6):544-554.   Published online November 30, 2014
DOI: https://doi.org/10.5946/ce.2014.47.6.544
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background/Aims

In order to reduce the procedure time and the number of accessory changes during endoscopic submucosal dissection (ESD), we developed a novel versatile knife, which has the combined advantages of several conventional knives. The aim of this study was to compare the efficacy, safety, and histological quality of ESD performed using this novel versatile knife and a combination of several conventional knives.

Methods

This was an in vivo animal study comparing two different modalities of ESD in mini-pigs. Completion time of each resection was documented, and the resected specimens were retrieved and evaluated for completeness. To assess the quality control of the procedures and adverse events, detailed histopathological examinations were performed.

Results

A total of 18 specimens were dissected by ESD safely and easily (nine specimens using the new versatile knife; nine specimens by mixing conventional knives). All resections were completed as en bloc resections. There was no significant difference in procedure time between the 2 modalities (456 seconds vs. 355 seconds, p=0.258) and cutting speed (1.983 mm2/sec vs. 1.57 mm2/sec, p=1.000). The rate of adverse events and histological quality did not statistically differ between the modalities.

Conclusions

ESD with a versatile knife appeared to be an easy, safe, and technically efficient method.

Citations

Citations to this article as recorded by  
  • Comparison of synchronous dual wavelength diode laser versus conventional endo-knives for esophageal endoscopic submucosal dissection: an animal study
    Jian Tang, Shufang Ye, Xueliang Ji, Jun Li, Feng Liu
    Surgical Endoscopy.2018; 32(12): 5037.     CrossRef
  • Technological review on endoscopic submucosal dissection: available equipment, recent developments and emerging techniques
    Georgios Mavrogenis, Juergen Hochberger, Pierre Deprez, Morteza Shafazand, Dimitri Coumaros, Katsumi Yamamoto
    Scandinavian Journal of Gastroenterology.2017; 52(4): 486.     CrossRef
  • 7,272 View
  • 60 Download
  • 3 Web of Science
  • 2 Crossref
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Review
Molecular Imaging for Theranostics in Gastroenterology: One Stone to Kill Two Birds
Kwang Hyun Ko, Chang-Il Kown, Jong Min Park, Hoo Geun Lee, Na Young Han, Ki Baik Hahm
Clin Endosc 2014;47(5):383-388.   Published online September 30, 2014
DOI: https://doi.org/10.5946/ce.2014.47.5.383
AbstractAbstract PDFPubReaderePub

Molecular imaging in gastroenterology has become more feasible with recent advances in imaging technology, molecular genetics, and next-generation biochemistry, in addition to advances in endoscopic imaging techniques including magnified high-resolution endoscopy, narrow band imaging or autofluorescence imaging, flexible spectral imaging color enhancement, and confocal laser endomicroscopy. These developments have the potential to serve as "red flag" techniques enabling the earlier and accurate detection of mucosal abnormalities (such as precancerous lesions) beyond biomarkers, virtual histology of detected lesions, and molecular targeted therapy-the strategy of "one stone to kill two or three birds"; however, more effort should be done to be "blue ocean" benefit. This review deals with the introduction of Raman spectroscopy endoscopy, imaging mass spectroscopy, and nanomolecule development for theranostics. Imaging of molecular pathological changes in cells/tissues/organs might open the "royal road" to either convincing diagnosis of diseases that otherwise would only be detected in the advanced stages or novel therapeutic methods targeted to personalized medicine.

Citations

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  • A supramolecular colloidal system based on folate-conjugated β-cyclodextrin polymer and indocyanine green for enhanced tumor-targeted cell imaging in 2D culture and 3D tumor spheroids
    Yuting Wen, Jianfeng Wang, Wei Zheng, Jingling Zhu, Xia Song, Taili Chen, Miao Zhang, Zhiwei Huang, Jun Li
    Journal of Colloid and Interface Science.2024; 667: 259.     CrossRef
  • ESR Position Paper on Imaging Biobanks

    Insights into Imaging.2015; 6(4): 403.     CrossRef
  • International Digestive Endoscopy Network 2014: Turnpike to the Future
    Eun Young Kim, Kwang An Kwon, Il Ju Choi, Ji Kon Ryu, Ki Baik Hahm
    Clinical Endoscopy.2014; 47(5): 371.     CrossRef
  • 8,684 View
  • 72 Download
  • 3 Web of Science
  • 3 Crossref
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Focused Review Series: Endoscopic and Molecular Imaging of Premalignant GI Lesions, Part II
Recent Advances in Molecular Imaging of Premalignant Gastrointestinal Lesions and Future Application for Early Detection of Barrett Esophagus
Kwang Hyun Ko, Na Young Han, Chang Il Kwon, Hoo Keun Lee, Jong Min Park, Eun Hee Kim, Ki Baik Hahm
Clin Endosc 2014;47(1):7-14.   Published online January 24, 2014
DOI: https://doi.org/10.5946/ce.2014.47.1.7
AbstractAbstract PDFPubReaderePub

Recent advances in optical molecular imaging allow identification of morphologic and biochemical changes in tissues associated with gastrointestinal (GI) premalignant lesions earlier and in real-time. This focused review series introduces high-resolution imaging modalities that are being evaluated preclinically and clinically for the detection of early GI cancers, especially Barrett esophagus and esophageal adenocarcinoma. Although narrow band imaging, autofluorescence imaging, and chromoendoscopy are currently applied for this purpose in the clinic, further adoptions of probe-based confocal laser endomicroscopy, high-resolution microendoscopy, optical coherence tomography, and metabolomic imaging, as well as imaging mass spectrometry, will lead to detection at the earliest and will guide predictions of the clinical course in the near future in a manner that is beyond current advancements in optical imaging. In this review article, the readers will be introduced to sufficient information regarding this matter with which to enjoy this new era of high technology and to confront science in the field of molecular medical imaging.

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  • Fluorescence imaging-guided surgery: current status and future directions
    Zia Ullah, Shubham Roy, Saz Muhammad, Chen Yu, Haiyan Huang, Dongxiang Chen, Haodong Long, Xiulan Yang, Xuelian Du, Bing Guo
    Biomaterials Science.2024;[Epub]     CrossRef
  • Pivotal Role of Peptides in Gastric Carcinoma: Diagnosis and Therapy
    Sajjad Ahmadpour, Fatemeh Khodadust, Ahmad Hormati, Karim Eivaziatashbeik
    International Journal of Peptide Research and Therapeutics.2021; 27(1): 503.     CrossRef
  • High-resolution proteomics and metabolomics in thyroid cancer: Deciphering novel biomarkers
    Diana Navas-Carrillo, José Manuel Rodriguez, Silvia Montoro-García, Esteban Orenes-Piñero
    Critical Reviews in Clinical Laboratory Sciences.2017; 54(7-8): 446.     CrossRef
  • hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett's esophagus and can be exploited for a novel endoscopic surveillance
    Elena Lastraioli, Tiziano Lottini, Jessica Iorio, Giancarlo Freschi, Marilena Fazi, Claudia Duranti, Laura Carraresi, Luca Messerini, Antonio Taddei, Maria Novella Ringressi, Marianna Salemme, Vincenzo Villanacci, Carla Vindigni, Anna Tomezzoli, Roberta L
    Oncotarget.2016; 7(37): 59535.     CrossRef
  • Imaging Mass Spectrometry in Papillary Thyroid Carcinoma for the Identification and Validation of Biomarker Proteins
    Kyueng-Whan Min, Joo-Young Bang, Kwang Pyo Kim, Wan-Seop Kim, Sang Hwa Lee, Selina Rahman Shanta, Jeong Hwa Lee, Ji Hye Hong, So Dug Lim, Young-Bum Yoo, Chan-Hyun Na
    Journal of Korean Medical Science.2014; 29(7): 934.     CrossRef
  • Molecular Imaging for Theranostics in Gastroenterology: One Stone to Kill Two Birds
    Kwang Hyun Ko, Chang-Il Kown, Jong Min Park, Hoo Geun Lee, Na Young Han, Ki Baik Hahm
    Clinical Endoscopy.2014; 47(5): 383.     CrossRef
  • 6,728 View
  • 63 Download
  • 8 Web of Science
  • 6 Crossref
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Focused Review Series: Endoscopic and Molecular Imaging of Premalignant GI Lesions, Part I
Application of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Imaging Mass Spectrometry (MALDI-TOF IMS) for Premalignant Gastrointestinal Lesions
Kwang Hyun Ko, Chang Il Kwon, So Hye Park, Na Young Han, Hoo Keun Lee, Eun Hee Kim, Ki Baik Hahm
Clin Endosc 2013;46(6):611-619.   Published online November 19, 2013
DOI: https://doi.org/10.5946/ce.2013.46.6.611
AbstractAbstract PDFPubReaderePub

Imaging mass spectrometry (IMS) is currently receiving large attention from the mass spectrometric community, although its use is not yet well known in the clinic. As matrix-assisted laser desorption/ionization time-of-flight (MALDI)-IMS can show the biomolecular changes in cells as well as tissues, it can be an ideal tool for biomedical diagnostics as well as the molecular diagnosis of clinical specimens, especially aimed at the prompt detection of premalignant lesions much earlier before overt mass formation, or for obtaining histologic clues from endoscopic biopsy. Besides its use for pathologic diagnosis, MALDI-IMS is also a powerful tool for the detection and localization of drugs, proteins, and lipids in tissue. Measurement of parameters that define and control the implications, challenges, and opportunities associated with the application of IMS to biomedical tissue studies might be feasible through a deep understanding of mass spectrometry. In this focused review series, new insights into the molecular processes relevant to IMS as well as other field applications are introduced.

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    Li Zhou, Qifu Li, Jiandong Wang, Canhua Huang, Edouard C. Nice
    PROTEOMICS – Clinical Applications.2016; 10(4): 516.     CrossRef
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    Guanheng Ren, Donghua Zou, Ping Huang, Zhengdong Li, Yu Shao, Kaifei Deng, Yijiu Chen, Ningguo Liu
    American Journal of Forensic Medicine & Pathology.2016; 37(4): 279.     CrossRef
  • Surface-Assisted Laser Desorption/Ionization of Trinitrotoluene on Porous Silicon under Ambient Conditions
    Yury Kuzishchin, Igor Martynov, Dmitriy Dovzhenko, Gennadii Kotkovskii, Alexander Chistyakov
    The Journal of Physical Chemistry C.2015; 119(11): 6382.     CrossRef
  • Imaging Mass Spectrometry in Papillary Thyroid Carcinoma for the Identification and Validation of Biomarker Proteins
    Kyueng-Whan Min, Joo-Young Bang, Kwang Pyo Kim, Wan-Seop Kim, Sang Hwa Lee, Selina Rahman Shanta, Jeong Hwa Lee, Ji Hye Hong, So Dug Lim, Young-Bum Yoo, Chan-Hyun Na
    Journal of Korean Medical Science.2014; 29(7): 934.     CrossRef
  • Recent Advances in Molecular Imaging of Premalignant Gastrointestinal Lesions and Future Application for Early Detection of Barrett Esophagus
    Kwang Hyun Ko, Na Young Han, Chang Il Kwon, Hoo Keun Lee, Jong Min Park, Eun Hee Kim, Ki Baik Hahm
    Clinical Endoscopy.2014; 47(1): 7.     CrossRef
  • Molecular Imaging for Theranostics in Gastroenterology: One Stone to Kill Two Birds
    Kwang Hyun Ko, Chang-Il Kown, Jong Min Park, Hoo Geun Lee, Na Young Han, Ki Baik Hahm
    Clinical Endoscopy.2014; 47(5): 383.     CrossRef
  • Predictive proteomic biomarkers for inflammatory bowel disease-associated cancer: Where are we now in the era of the next generation proteomics?
    Jong-Min Park
    World Journal of Gastroenterology.2014; 20(37): 13466.     CrossRef
  • 8,439 View
  • 65 Download
  • 7 Crossref
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Case Report
Gastrointestinal Cancers in a Peutz-Jeghers Syndrome Family: A Case Report
Sang Hee Song, Kun Woo Kim, Won Hee Kim, Chang Il Kwon, Kwang Hyun Ko, Ki Baik Hahm, Pil Won Park, Sung Pyo Hong
Clin Endosc 2013;46(5):572-575.   Published online September 30, 2013
DOI: https://doi.org/10.5946/ce.2013.46.5.572
AbstractAbstract PDFPubReaderePub

A 17-year-old man was diagnosed as Peutz-Jeghers syndrome (PJS) because of pigmented lip and multiple gastrointestinal polyps. He had anemia and underwent polypectomy on the duodenum and colon. His maternal family members were patients with PJS. His mother used to be screened with endoscopy to remove large polyps. One and half years later, he underwent jejunal segmental resection due to intussusceptions. He underwent endoscopic polypectomy every 2 to 3 years. When he was 23 years old, high-grade dysplasia was found in colonic polyp and his mother underwent partial pancreatectomy due to intraductal papillary mucinous carcinoma. When he was 27 years old, diffuse gastric polyps on the greater curvature of corpus expanded and grew. Therefore, wide endoscopic polypectomy was done. Histological examination revealed focal intramucosal carcinoma and low-grade dysplasia in hamartomatous polyps. We report cases of cancers occurred in first-degree relatives with PJS.

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    Fátima Carneiro
    Best Practice & Research Clinical Gastroenterology.2022; 58-59: 101800.     CrossRef
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    Jin Young Park, Lawrence von Karsa, Rolando Herrero
    Clinical Endoscopy.2014; 47(6): 478.     CrossRef
  • 6,607 View
  • 58 Download
  • 6 Crossref
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Special Issue Article of IDEN 2013
Functional Self-Expandable Metal Stents in Biliary Obstruction
Chang-Il Kwon, Kwang Hyun Ko, Ki Baik Hahm, Dae Hwan Kang
Clin Endosc 2013;46(5):515-521.   Published online September 30, 2013
DOI: https://doi.org/10.5946/ce.2013.46.5.515
AbstractAbstract PDFPubReaderePub

Biliary stents are widely used not only for palliative treatment of malignant biliary obstruction but also for benign biliary diseases. Each plastic stent or self-expandable metal stent (SEMS) has its own advantages, and a proper stent should be selected carefully for individual condition. To compensate and overcome several drawbacks of SEMS, functional self-expandable metal stent (FSEMS) has been developed with much progress so far. This article looks into the outcomes and defects of each stent type for benign biliary stricture and describes newly introduced FSEMSs according to their functional categories.

Citations

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  • Anti-fibrotic and anti-stricture effects of biodegradable biliary stents braided with dexamethasone-impregnated sheath/core structured monofilaments
    Ju-Ro Lee, Seung Won Yang, Chang-Il Kwon, Kyu Seok Kim, Se Hwan Park, Myeong Jin Jang, Ga Hee Kim, Min Je Sung, Gwangil Kim, Jun Sik Son, Yoon Ki Joung
    Acta Biomaterialia.2024; 178: 137.     CrossRef
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    Nga T. Nguyen, Hasan A. Khan, Kian Abdul-Baki, Woongsoon Choi, Neel K. Shroff, Zahra Akhtar, Peeyush Bhargava
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Original Article
Angular Positioning of Stent Increases Bowel Perforation after Self-Expandable Metal Stent Placement for Malignant Colorectal Obstruction
Jeong Guil Lee, Kwang Ho Yoo, Chang-Il Kwon, Kwang Hyun Ko, Sung Pyo Hong
Clin Endosc 2013;46(4):384-389.   Published online July 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.4.384
AbstractAbstract PDFPubReaderePub
Background/Aims

Some factors like stent wires, balloon dilatation and use of guide wires seems to increase perforation after self-expandable metal stent (SEMS) placement, but few studies mentioned about the relationship between angulation of malignant stricture and perforation. The present study aimed to confirm that more angular positioning of stents increases perforation.

Methods

This study was conducted with retrospectively evaluation at Digestive Disease Center, CHA Bundang Medical Center, CHA University. Between January 2002 and August 2011, SEMS was inserted in 130 patients with malignant colorectal obstruction. We studied the difference in the angle of stenosis between perforation and non-perforation groups using fluorography images.

Results

SEMS insertion was performed in 130 cases of obstruction due to colon cancer. Perforation occurred in eight patients (6.2%) of them. Thirteen cases were excluded from the analysis due to poor fluoroscopic images. Among the eight patients with perforation, the mean stenosis angle was 109.9° compared to 153.1° in the nonperforation group, indicating that the angle was more acute in the perforation group (p=0.016).

Conclusions

This study shows that more angular positioning of stent increases bowel perforation after SEMS placement for malignant colorectal obstruction.

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Commentary
Harmony of Duet over Solo: Use of Midazolam or Propofol for Sedative Endoscopy in Pediatric Patients
Kwang Hyun Ko, Ki Baik Hahm
Clin Endosc 2013;46(4):311-312.   Published online July 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.4.311
PDFPubReaderePub

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Review
Unusual Complications Related to Endoscopic Retrograde Cholangiopancreatography and Its Endoscopic Treatment
Chang-Il Kwon, Sang Hee Song, Ki Baik Hahm, Kwang Hyun Ko
Clin Endosc 2013;46(3):251-259.   Published online May 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.3.251
AbstractAbstract PDFPubReaderePub

Endoscopic retrograde cholangiopancreatography (ERCP)-induced complications, once occurred, can lead to significant morbidity. Commonly 5% to 10% of patients experience procedure related complications such as post-ERCP pancreatitis, biliary hemorrhage, and cholangitis, in descending order. However, complications such as perforation, pneumothorax, air embolism, splenic injury, and basket impaction are rare but are associated with high mortality if occurred. Such unexpected unusual complications might extend the length of hospitalization, require urgent surgical intervention, and put the patient in miserable condition leading to permanent disability or mortality. Although these ERCP-induced complications can be minimized by a skilled operator using advanced techniques and devices, the occurrence of unusual complications are hard to expect and induce very difficult management condition. In this review, we will focus on the uncommon complications related to ERCP. This review is also aimed at suggesting optimal endoscopic treatment strategies for several complications based on our institutional experiences.

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Brief Report
Balloon Catheter Assisted Biliary Stent Insertion
Chang-Il Kwon, Kwang Hyun Ko
Clin Endosc 2013;46(2):201-202.   Published online March 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.2.201
PDFPubReaderePub

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Case Report
An Impacted Pancreatic Stone in the Papilla Induced Acute Obstructive Cholangitis in a Patient with Chronic Pancreatitis
Kwang-Ho Yoo, Chang-Il Kwon, Sang-Wook Yoon, Won Hee Kim, Jung Min Lee, Kwang Hyun Ko, Sung Pyo Hong, Pil Won Park
Clin Endosc 2012;45(1):99-102.   Published online March 31, 2012
DOI: https://doi.org/10.5946/ce.2012.45.1.99
AbstractAbstract PDFPubReaderePub

Obstructive jaundice is very rarely caused by impaction of a pancreatic stone in the papilla. We report here on a case of obstructive jaundice with acute cholangitis that was caused by an impacted pancreatic stone in the papilla in a patient with chronic pancreatitis. A 48-year-old man presented with acute obstructive cholangitis. Abdominal computed tomography with the reconstructed image revealed distal biliary obstruction that was caused by a pancreatic stone in the pancreatic head, and there was also pancreatic ductal dilatation and parenchymal atrophy of the pancreatic body and tail with multiple calcifications. Emergency duodenoscopy revealed an impacted pancreatic stone in the papilla. Precut papillotomy using a needle knife was performed, followed by removal of the pancreatic stone using grasping forceps. After additional sphincterotomy, a large amount of dark-greenish bile juice gushed out. The patient rapidly improved and he has remained well.

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