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Original Articles
- The Clinical Usefulness of Simultaneous Placement of Double Endoscopic Nasobiliary Biliary Drainage
- Hong Jun Kim, Sung Koo Lee, Choong Heon Ryu, Do Hyun Park, Sang Soo Lee, Dong Wan Seo, Myung-Hwan Kim
- Clin Endosc 2015;48(6):542-548. Published online November 30, 2015
- DOI: https://doi.org/10.5946/ce.2015.48.6.542
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Abstract
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ePub - Background
/Aims: To evaluate the technical feasibility and clinical efficacy of double endoscopic nasobiliary drainage (ENBD) as a new method of draining multiple bile duct obstructions.
Methods
A total of 38 patients who underwent double ENBD between January 2004 and February 2010 at the Asan Medical Center were retrospectively analyzed. We evaluated indications, laboratory results, and the clinical course.
Results
Of the 38 patients who underwent double ENBD, 20 (52.6%) had Klatskin tumors, 12 (31.6%) had hepatocellular carcinoma, 3 (7.9%) had strictures at the anastomotic site following liver transplantation, and 3 (7.9%) had acute cholecystitis combined with cholangitis. Double ENBD was performed to relieve multiple biliary obstruction in 21 patients (55.1%), drain contrast agent filled during endoscopic retrograde cholangiopancreatography in 4 (10.5%), obtain cholangiography in 4 (10.5%), drain hemobilia in 3 (7.9%), relieve Mirizzi syndrome with cholangitis in 3 (7.9%), and relieve jaundice in 3 (7.9%).
Conclusions
Double ENBD may be useful in patients with multiple biliary obstructions. -
Citations
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- High-throughput metabolomics reveals the perturbed metabolic pathways and biomarkers of Yang Huang syndrome as potential targets for evaluating the therapeutic effects and mechanism of geniposide
Heng Fang, Aihua Zhang, Xiaohang Zhou, Jingbo Yu, Qi Song, Xijun Wang
Frontiers of Medicine.2020; 14(5): 651. CrossRef - Can Endoscopic Nasobiliary Drainage Involving Two Catheters Be Used to Treat Various Conditions?
Dong Wook Lee, Ho Gak Kim
Clinical Endoscopy.2015; 48(6): 464. CrossRef
- High-throughput metabolomics reveals the perturbed metabolic pathways and biomarkers of Yang Huang syndrome as potential targets for evaluating the therapeutic effects and mechanism of geniposide
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- 105 Download
- 2 Web of Science
- 2 Crossref
- Endoscopic Ultrasonography-Guided Ethanol Ablation for Small Pancreatic Neuroendocrine Tumors: Results of a Pilot Study
- Do Hyun Park, Jun-Ho Choi, Dongwook Oh, Sang Soo Lee, Dong-Wan Seo, Sung Koo Lee, Myung-Hwan Kim
- Clin Endosc 2015;48(2):158-164. Published online March 27, 2015
- DOI: https://doi.org/10.5946/ce.2015.48.2.158
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Abstract
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Background/Aims Endoscopic ultrasonography (EUS)-guided ethanol ablation is gaining popularity for the treatment of focal pancreatic lesions. The aim of this study was to evaluate the safety, feasibility, and treatment response after EUS-guided ethanol injection for small pancreatic neuroendocrine tumors (p-NETs).
Methods This was a retrospective analysis of a prospectively collected database including 11 consecutive patients with p-NETs who underwent EUS-guided ethanol injection.
Results EUS-guided ethanol injection was successfully performed in 11 patients with 14 tumors. The final diagnosis was based on histology and clinical signs as follows: 10 non-functioning neuroendocrine tumors and four insulinomas. During follow-up (median, 370 days; range, 152 to 730 days), 10 patients underwent clinical follow-up after treatment, and one patient was excluded because of loss to follow-up. A single treatment session with an injection of 0.5 to 3.8 mL of ethanol resulted in complete responses (CRs) at the 3-month radiologic imaging for seven of 13 tumors (response rate, 53.8%). Multiple treatment sessions performed in three tumors with residual viable enhancing tissue increased the number of tumors with CRs to eight of 13 (response rate, 61.5%). Mild pancreatitis occurred in three of 11 patients.
Conclusions EUS-guided ethanol injection appears to be a safe, feasible, and potentially effective method for treating small p-NETs in patients who are poor surgical candidates.
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Citations
Citations to this article as recorded by- Efficacy and safety of endoscopic ultrasonography-guided ethanol injections of small pancreatic neuroendocrine neoplasms: a prospective multicenter study
Kazuyuki Matsumoto, Hironari Kato, Takao Itoi, Masayuki Kitano, Kazuo Hara, Masaki Kuwatani, Mamoru Takenaka, Reiko Ashida, Shuntaro Mukai, Nozomi Okuno, Kazumichi Kawakubo, Tatsuhiro Yamazaki, Jun Sakurai, Yuki Nakatsuka, Michihiro Yoshida, Motoyuki Otsu
Endoscopy.2025; 57(04): 321. CrossRef - Reducing the incidence of pancreatic cancer through radiofrequency ablation of mucinous cystic neoplasms: What is the evidence?
Pujitha Kudaravalli, Sahib Singh, Rakesh Vinayek, Ganesh Aswath, Stefano Francesco Crinò, Jorge Machicado, Antonio Facciorusso
Best Practice & Research Clinical Gastroenterology.2025; 74: 101986. CrossRef - Endoscopic Ultrasound-Guided Locoregional Treatments for Pancreatic Neuroendocrine Neoplasms
Graziella Masciangelo, Davide Campana, Claudio Ricci, Elisa Andrini, Emilija Rakichevikj, Pietro Fusaroli, Andrea Lisotti
Current Oncology.2025; 32(2): 113. CrossRef - Role of endoscopic ultrasound in the diagnosis and local ablative therapy of pancreatic neuroendocrine tumors
Yun Je Song, Jun Kyeong Lim, Jun-Ho Choi
The Korean Journal of Internal Medicine.2025; 40(2): 170. CrossRef - Role of Endoscopic Ultrasound Ablative Therapy in Management of Pancreatic Neuroendocrine Tumors: a Systematic Review
Bharath S, Ashutosh Carpenter, Sanjay Kumar Yadav, Vikesh Agarwal, Uday Somashekhar, Dhananjaya Sharma
Indian Journal of Surgery.2024; 86(S1): 145. CrossRef - Portuguese Pancreatic Club Perspectives on Endoscopic Ultrasound-Guided and Surgical Treatment of Pancreatic Neuroendocrine Tumors
Tiago Ribeiro, Sara Castanheira-Rodrigues, Pedro Bastos, Humberto Cristino, Alexandra Fernandes, Eduardo Rodrigues-Pinto, Miguel Bispo, Ricardo Rio-Tinto, Filipe Vilas-Boas
GE - Portuguese Journal of Gastroenterology.2024; 31(4): 225. CrossRef - Endoscopic Management of Gastro-Entero-Pancreatic Neuroendocrine Tumours: An Overview of Proposed Resection and Ablation Techniques
Rocio Chacchi-Cahuin, Edward J. Despott, Nikolaos Lazaridis, Alessandro Rimondi, Giuseppe Kito Fusai, Dalvinder Mandair, Andrea Anderloni, Valentina Sciola, Martyn Caplin, Christos Toumpanakis, Alberto Murino
Cancers.2024; 16(2): 352. CrossRef - A single-center experience on endoscopic ultrasonography-guided ethanol ablation of insulinomas
Zhiyu Yan, Cheng Zhu, Xi Wu, Huijuan Zhu, Tao Yuan, Yaping Luo, Yunlu Feng, Qiang Wang, Shengyu Zhang, Huadan Xue, Zehui Zheng, Aiming Yang
Pancreatology.2023; 23(1): 98. CrossRef - Endoscopic ablation therapy for the pancreatic neoplasms
Kazuyuki Matsumoto, Hironari Kato
Digestive Endoscopy.2023; 35(4): 430. CrossRef - Comparison of EUS-guided ablation and surgical resection for nonfunctioning small pancreatic neuroendocrine tumors: a propensity score–matching study
Hoonsub So, Sung Woo Ko, Seung Hwan Shin, Eun Ha Kim, Jimin Son, SuHyun Ha, Ki Byung Song, Hwa Jung Kim, Myung-Hwan Kim, Do Hyun Park
Gastrointestinal Endoscopy.2023; 97(4): 741. CrossRef - Efficacy and predictive factors of endoscopic ultrasound-guided ethanol ablation in benign solid pancreatic tumors
Jin Ho Choi, Woo Hyun Paik, Sang Hyub Lee, Min Woo Lee, In Rae Cho, Ji Kon Ryu, Yong-Tae Kim
Surgical Endoscopy.2023; 37(8): 5960. CrossRef - Current status of the role of endoscopy in evaluation and management of gastrointestinal and pancreatic neuroendocrine tumors
Zaheer Nabi, Sundeep Lakhtakia, D. Nageshwar Reddy
Indian Journal of Gastroenterology.2023; 42(2): 158. CrossRef - Endoscopic Ultrasound-Guided Local Ablative Therapies for the Treatment of Pancreatic Neuroendocrine Tumors and Cystic Lesions: A Review of the Current Literature
Alexander M. Prete, Tamas A. Gonda
Journal of Clinical Medicine.2023; 12(9): 3325. CrossRef - Performance and Safety of EUS Ablation Techniques for Pancreatic Cystic Lesions: A Systematic Review and Meta-Analysis
Apostolis Papaefthymiou, Gavin J. Johnson, Marcello Maida, Paraskevas Gkolfakis, Daryl Ramai, Antonio Facciorusso, Marianna Arvanitakis, Alexander Ney, Giuseppe K. Fusai, Adrian Saftoiu, Daniela Tabacelia, Simon Phillpotts, Michael H. Chapman, George J. W
Cancers.2023; 15(9): 2627. CrossRef - Evolution of Pancreatic Endotherapy
YongYan Cui, Richard A. Kozarek
Gastrointestinal Endoscopy Clinics of North America.2023; 33(4): 679. CrossRef - An Overview of Pancreatic Neuroendocrine Tumors and an Update on Endoscopic Techniques for Their Management
Osama O. Elkelany, Fred G. Karaisz, Benjamin Davies, Somashekar G. Krishna
Current Oncology.2023; 30(8): 7566. CrossRef - Current status of endoscopic ultrasound (EUS)-guided ablation therapy for pancreatic neuroendocrine neoplasms (PNENs)
Hironari KATO, Kazuyuki MATSUMOTO
Suizo.2023; 38(4): 229. CrossRef - Multiple endocrine neoplasia type 1 (MEN-1) and neuroendocrine neoplasms (NENs)
Grigoris Effraimidis, Ulrich Knigge, Maria Rossing, Peter Oturai, Åse Krogh Rasmussen, Ulla Feldt-Rasmussen
Seminars in Cancer Biology.2022; 79: 141. CrossRef - Safety and efficacy of EUS-guided ablation of pancreatic lesions with ethanol versus ethanol with paclitaxel: A systematic review and meta-analysis
Syed Mohsin Saghir, Banreet Singh Dhindsa, Sarav Gunjit Singh Daid, Yassin Naga, Amaninder Dhaliwal, Harmeet S. Mashiana, Neil Bhogal, Harlan Sayles, Daryl Ramai, Shailender Singh, Ishfaq Bhat, Rajani Rangray, Stephanie McDonough, Douglas G. Adler
Endoscopic Ultrasound.2022; 11(5): 371. CrossRef - Usefulness of contrast‐enhanced endoscopic ultrasonography for the treatment of ethanol reinjection in patient with small pancreatic neuroendocrine neoplasm
Kazuyuki Matsumoto, Hironari Kato, Hiroyuki Okada
Digestive Endoscopy.2022;[Epub] CrossRef - Endotherapy in Pancreatic Diseases
Vaneet Jearth, Surinder S. Rana
Journal of Digestive Endoscopy.2022; 13(01): 019. CrossRef - EUS-guided radiofrequency and ethanol ablation for pancreatic neuroendocrine tumors
Rajat Garg, Abdul Mohammed, Amandeep Singh, Mary P. Harnegie, Tarun Rustagi, Tyler Stevens, Prabhleen Chahal
Endoscopic Ultrasound.2022; 11(3): 170. CrossRef - EUS-guided ablation of pancreatic neoplasms
Mihai RIMBAȘ, Gianenrico RIZZATTI, Alberto LARGHI
Minerva Gastroenterology.2022;[Epub] CrossRef - Endoscopic techniques for diagnosis and treatment of gastro-entero-pancreatic neuroendocrine neoplasms: Where we are
Roberta Elisa Rossi, Alessandra Elvevi, Camilla Gallo, Andrea Palermo, Pietro Invernizzi, Sara Massironi
World Journal of Gastroenterology.2022; 28(26): 3258. CrossRef - The global research status and trends of the application of endoscopic ultrasonography in pancreatic tumors over the last decades: A bibliometric study
Chuanchao Xia, Hua Yin, Kecheng Zhang, Zhenhuan Wang, Xiaoli Yang, Haojie Huang
Frontiers in Oncology.2022;[Epub] CrossRef - Role of Endoscopy in Management of Upper Gastrointestinal Cancers
Jeff Liang, Yi Jiang, Yazan Abboud, Srinivas Gaddam
Diseases.2022; 11(1): 3. CrossRef - Endoscopic ultrasound-guided therapies for pancreatic solid tumors: An overview
Alberto Larghi, Mihai Rimbaș, Gianenrico Rizzatti, Carmine Carbone, Antonio Gasbarrini, Guido Costamagna, Sergio Alfieri, Giampaolo Tortora
Seminars in Oncology.2021; 48(1): 95. CrossRef - Role of Radiofrequency Ablation in the Management of Unresectable Pancreatic Cancer
Muhammad Nadeem Yousaf, Hamid Ehsan, Ahmad Muneeb, Ahsan Wahab, Muhammad K. Sana, Karun Neupane, Fizah S. Chaudhary
Frontiers in Medicine.2021;[Epub] CrossRef - Insulinoma: A Recurrent Pancreatic Tumor Amendable to Computed Tomography–Guided Ethanol-Lipiodol Injection
Himesh B. Zaver, Khaled I. Alnahhal, Hassan Ghoz, Ricardo Paz-Fumagalli, Massimo Raimondo, Frank J. Lukens
ACG Case Reports Journal.2021; 8(2): e00539. CrossRef - Diagnostic Role and Therapeutic Perspectives of Endoscopic Ultrasound for Pancreatic Neuroendocrine Tumor
Jun-Ho Choi
The Korean Journal of Pancreas and Biliary Tract.2021; 26(1): 1. CrossRef - Multiple Endocrine Neoplasia Type 1: Latest Insights
Maria Luisa Brandi, Sunita K Agarwal, Nancy D Perrier, Kate E Lines, Gerlof D Valk, Rajesh V Thakker
Endocrine Reviews.2021; 42(2): 133. CrossRef - Endoscopic Therapy for Pancreatic Benign Neoplasms
Jun Seong Hwang, Sung Woo Ko
Journal of Digestive Cancer Reports.2021; 9(1): 25. CrossRef - It's not a mystery, it's in the history: Multidisciplinary management of multiple endocrine neoplasia type 1
Aditya S. Shirali, Carolina R. C. Pieterman, Mark A. Lewis, Samuel M. Hyde, Shalini Makawita, Arvind Dasari, Nirav Thosani, Naruhiko Ikoma, Ian E. McCutcheon, Steven G. Waguespack, Nancy D. Perrier
CA: A Cancer Journal for Clinicians.2021; 71(5): 369. CrossRef - Diagnostic and Interventional Role of Endoscopic Ultrasonography for the Management of Pancreatic Neuroendocrine Neoplasms
Giuseppinella Melita, Socrate Pallio, Andrea Tortora, Stefano Francesco Crinò, Antonio Macrì, Gianlorenzo Dionigi
Journal of Clinical Medicine.2021; 10(12): 2638. CrossRef - Study protocol for endoscopic ultrasonography-guided ethanol injection therapy for patients with pancreatic neuroendocrine neoplasm: a multicentre prospective study
Kazuyuki Matsumoto, Hironari Kato, Masayuki Kitano, Kazuo Hara, Masaki Kuwatani, Reiko Ashida, Mamoru Takenaka, Tatsuhiro Yamazaki, Jun Sakurai, Michihiro Yoshida, Hiroyuki Okada
BMJ Open.2021; 11(7): e046505. CrossRef - Surgical outcomes are hampered after endoscopic ultrasonography-guided ethanol lavage and/or Taxol injection in cystic lesions of the pancreas
Seong-Ryong Kim, Song Cheol Kim, Ki Byung Song, Kwang-Min Park, Dae Wook Hwang, Jae Hoon Lee, Sang Hyun Shin, Bong Jun Kwak, Young-Joo Lee
Annals of Hepato-Biliary-Pancreatic Surgery.2021; 25(3): 342. CrossRef - The Role of Contrast-Enhanced Harmonic Endoscopic Ultrasound in Interventional Endoscopic Ultrasound
Cecilia Binda, Chiara Coluccio, Gianmarco Marocchi, Monica Sbrancia, Carlo Fabbri
Medicina.2021; 57(10): 1085. CrossRef - Endoscopic ultrasound-guided ethanol and radiofrequency ablation of pancreatic insulinomas: a systematic literature review
Ghassan El Sayed, Levente Frim, Jamie Franklin, Raymond McCrudden, Charles Gordon, Safa Al-Shamma, Szabolcs Kiss, Péter Hegyi, Bálint Erőss, Péter Jenő Hegyi
Therapeutic Advances in Gastroenterology.2021;[Epub] CrossRef - Efficacy and safety of scheduled early endoscopic ultrasonography‐guided ethanol reinjection for patients with pancreatic neuroendocrine tumors: Prospective pilot study
Kazuyuki Matsumoto, Hironari Kato, Seiji Kawano, Hiroyasu Fujiwara, Kenji Nishida, Ryo Harada, Masakuni Fujii, Ryuichi Yoshida, Yuzo Umeda, Shiro Hinotsu, Takahito Yagi, Hiroyuki Okada
Digestive Endoscopy.2020; 32(3): 425. CrossRef - Endoscopic ultrasonography‐guided ethanol ablation of pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1 disease following complicated total pancreatectomy
Hsiang‐Hung Lin, Chen‐Wang Chang, Ming‐Jen Chen
Advances in Digestive Medicine.2020; 7(2): 97. CrossRef - EUS‐guided ethanol ablation for small pancreatic neuroendocrine neoplasm
Reiko Ashida
Digestive Endoscopy.2020; 32(3): 326. CrossRef - Interventional endoscopic ultrasound for pancreatic neuroendocrine neoplasms
Mihai Rimbaş, Mihaela Horumbă, Gianenrico Rizzatti, Stefano Francesco Crinò, Antonio Gasbarrini, Guido Costamagna, Alberto Larghi
Digestive Endoscopy.2020; 32(7): 1031. CrossRef - The safety and efficacy of endoscopic ultrasound-guided ablation therapy for solid pancreatic tumors: a systematic review
Lu Zhang, Shali Tan, Shu Huang, Chunyu Zhong, Muhan Lü, Yan Peng, Xiaowei Tang
Scandinavian Journal of Gastroenterology.2020; 55(9): 1121. CrossRef - Surgical Management of Neuroendocrine Tumours of the Pancreas
Regis Souche, Christian Hobeika, Elisabeth Hain, Sebastien Gaujoux
Journal of Clinical Medicine.2020; 9(9): 2993. CrossRef - Recent developments in endoscopic ultrasound-guided ablation treatment
Hoonsub So, Dongwook Oh, Dong-Wan Seo
International Journal of Gastrointestinal Intervention.2020; 9(4): 135. CrossRef - Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasound for the Guidance and Monitoring of Endoscopic Radiofrequency Ablation
Jun-Ho Choi, Dong-Wan Seo, Tae Jun Song, Do Hyun Park, Sang Soo Lee, Sung Koo Lee, Myung-Hwan Kim
Gut and Liver.2020; 14(6): 826. CrossRef - Treatment of Insulinomas with Minimally Invasive Physical Procedure. Literature Review
Stanislav V. Berelavichus, Andrey G. Kriger, Rimma S. Dugarova, Ayrat R. Kaldarov
SN Comprehensive Clinical Medicine.2019; 1(2): 104. CrossRef - Current Status of Endoscopic Ultrasound Techniques for Pancreatic Neoplasms
Yousuke Nakai, Naminatsu Takahara, Suguru Mizuno, Hirofumi Kogure, Kazuhiko Koike
Clinical Endoscopy.2019; 52(6): 527. CrossRef - Clinical impact of endoscopic ultrasonography on the management of neuroendocrine tumors: lights and shadows
Alessandra Zilli, Paolo Giorgio Arcidiacono, Dario Conte, Sara Massironi
Digestive and Liver Disease.2018; 50(1): 6. CrossRef - Outcomes after endoscopic ultrasound‐guided ethanol‐lipiodol ablation of small pancreatic neuroendocrine tumors
Jun‐Ho Choi, Do Hyun Park, Myung‐Hwan Kim, Hee Sang Hwang, Seung‐Mo Hong, Tae Jun Song, Sang Soo Lee, Dong‐Wan Seo, Sung Koo Lee
Digestive Endoscopy.2018; 30(5): 652. CrossRef - Endoscopic Management of Pancreatobiliary Neoplasms
Andrew Y. Wang, Patrick S. Yachimski
Gastroenterology.2018; 154(7): 1947. CrossRef - Future Perspectives on Endoscopic Ultrasonography-Guided Therapy for Pancreatic Neoplasm
Woo Hyun Paik, Sang Hyub Lee, Sunguk Jang
Clinical Endoscopy.2018; 51(3): 229. CrossRef - Imaging of pancreatic neuroendocrine tumors: recent advances, current status, and controversies
Lingaku Lee, Tetsuhide Ito, Robert T. Jensen
Expert Review of Anticancer Therapy.2018; 18(9): 837. CrossRef - Grading by the Ki-67 Labeling Index of Endoscopic Ultrasound–Guided Fine Needle Aspiration Biopsy Specimens of Pancreatic Neuroendocrine Tumors Can Be Underestimated
Hee Sang Hwang, YunJae Kim, Soyeon An, Sung Joo Kim, Joo Young Kim, Sang-Yeob Kim, Dae Wook Hwang, Do Hyun Park, Sang Soo Lee, Song Cheol Kim, Dong-Wan Seo, Seung-Mo Hong
Pancreas.2018; 47(10): 1296. CrossRef - Endoscopic ultrasonography‐guided tumor ablation
Sundeep Lakhtakia, Dong‐Wan Seo
Digestive Endoscopy.2017; 29(4): 486. CrossRef - Endoscopic Ultrasound-Guided Direct Intervention for Solid Pancreatic Tumors
Jimin Han, Kenneth J. Chang
Clinical Endoscopy.2017; 50(2): 126. CrossRef - Small pancreatic insulinoma: Successful endoscopic ultrasound‐guided radiofrequency ablation in a single session using a 22‐G fine needle
Francesc Bas‐Cutrina, Domingo Bargalló, Joan B. Gornals
Digestive Endoscopy.2017; 29(5): 636. CrossRef - Echoendoscopic ablative therapy for solid pancreatic tumors
Woo Hyun Paik, Dong Wan Seo
Journal of Digestive Diseases.2017; 18(3): 135. CrossRef - Recent Advances in Therapeutic Endosonography for Cancer Treatment
Saurabh Mukewar, Venkataraman Raman Muthusamy
Gastrointestinal Endoscopy Clinics of North America.2017; 27(4): 657. CrossRef - Endoscopic ultrasound guided tumor directed therapy and cyst ablation
Seyfettin Koklu, Omer Basar, William R. Brugge
Techniques in Gastrointestinal Endoscopy.2017; 19(4): 219. CrossRef - Therapy of Pancreatic Neuroendocrine Tumors: Fine Needle Intervention including Ethanol and Radiofrequency Ablation
Sundeep Lakhtakia
Clinical Endoscopy.2017; 50(6): 546. CrossRef - Diagnosis of Pancreatic Neuroendocrine Tumors
Dong Wook Lee, Michelle Kang Kim, Ho Gak Kim
Clinical Endoscopy.2017; 50(6): 537. CrossRef - Minimally Invasive Techniques for Resection of Pancreatic Neuroendocrine Tumors
Gustavo G. Fernandez Ranvier, Daniel Shouhed, William B. Inabnet
Surgical Oncology Clinics of North America.2016; 25(1): 195. CrossRef - Irreversible electroporation for the treatment of pancreatic neuroendocrine tumors
Michail Papamichail, Amir Ali, Michail Pizanias, Praveen Peddu, John Karani, Nigel Heaton
Korean Journal of Hepato-Biliary-Pancreatic Surgery.2016; 20(3): 116. CrossRef - Treatment of symptomatic neuroendocrine tumor syndromes: recent advances and controversies
Tetsuhide Ito, Lingaku Lee, Robert T. Jensen
Expert Opinion on Pharmacotherapy.2016; 17(16): 2191. CrossRef - Endoscopic Ultrasonography-Guided Ethanol Injection for a Pancreatic Neuroendocrine Tumor with Multiple Endocrine Neoplasia Type 1
Sujong An, Jae Yong Lee, Sung-ha Hwang, Do Hyun Park, Sung-Koo Lee
Korean Journal of Pancreas and Biliary Tract.2016; 21(4): 202. CrossRef - Interventional Therapy for Pancreatic Cancer
Jianwei Zhu, Zhendong Jin
Gastrointestinal Tumors.2016; 3(2): 81. CrossRef - The Expanding Role of Contrast-Enhanced Endoscopic Ultrasound in Pancreatobiliary Disease
Jun-Ho Choi, Dong Wan Seo
Gut and Liver.2015; 9(6): 707. CrossRef
- Efficacy and safety of endoscopic ultrasonography-guided ethanol injections of small pancreatic neuroendocrine neoplasms: a prospective multicenter study
- 8,641 View
- 129 Download
- 70 Web of Science
- 68 Crossref
- Comparison between Midazolam Used Alone and in Combination with Propofol for Sedation during Endoscopic Retrograde Cholangiopancreatography
- Yu Seok Kim, Myung-Hwan Kim, Seung Uk Jeong, Byung Uk Lee, Sang Soo Lee, Do Hyun Park, Dong-Wan Seo, Sung Koo Lee
- Clin Endosc 2014;47(1):94-100. Published online January 24, 2014
- DOI: https://doi.org/10.5946/ce.2014.47.1.94
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Abstract
PDFPubReaderePub
Background/Aims Endoscopic retrograde cholangiopancreatography (ERCP) is an uncomfortable procedure that requires adequate sedation for its successful conduction. We investigated the efficacy and safety of the combined use of intravenous midazolam and propofol for sedation during ERCP.
Methods A retrospective review of patient records from a single tertiary care hospital was performed. Ninety-four patients undergoing ERCP received one of the two medication regimens, which was administered by a nurse under the supervision of a gastroenterologist. Patients in the midazolam (M) group (
n =44) received only intravenous midazolam, which was titrated to achieve deep sedation. Patients in the midazolam pulse propofol (MP) group (n =50) initially received an intravenous combination of midazolam and propofol, and then propofol was titrated to achieve deep sedation.Results The time to the initial sedation was shorter in the MP group than in the M group (1.13 minutes vs. 1.84 minutes, respectively;
p <0.001). The recovery time was faster in the MP group than in the M group (p =0.031). There were no significant differences between the two groups with respect to frequency of adverse events, pain experienced by the patient, patient discomfort, degree of amnesia, and gag reflex. Patient cooperation, rated by the endoscopist as excellent, was greater in the MP group than in the M group (p =0.046).Conclusions The combined use of intravenous midazolam and propofol for sedation during ERCP is more effective than midazolam alone. There is no difference in the safety of the procedure.
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Citations
Citations to this article as recorded by- Sedation in the Endoscopy Suite
Katherine B. Hagan, Selvi Thirumurthi, Raju Gottumukkala, John Vargo
Current Treatment Options in Gastroenterology.2016; 14(2): 194. CrossRef - Sedation during endoscopic retrograde cholangiopancreatography: a randomized controlled study of patient-controlled propofol sedation and that given by a nurse anesthetist
Andreas Nilsson, Benjamin Grossmann, Eric Kullman, Eva Uustal, Folke Sjöberg, Lena Nilsson
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Young Duck Shin
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Kyong Hee Hong, Yun Jeong Lim
Clinical Endoscopy.2014; 47(4): 324. CrossRef
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- 5 Crossref
- Histological Changes in the Bile Duct after Long-Term Placement of a Fully Covered Self-Expandable Metal Stent within a Common Bile Duct: A Canine Study
- Sang Soo Lee, Tae Jun Song, Mee Joo, Do Hyun Park, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim
- Clin Endosc 2014;47(1):84-93. Published online January 24, 2014
- DOI: https://doi.org/10.5946/ce.2014.47.1.84
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Abstract
PDFPubReaderePub
Background/Aims To date, it has been difficult to determine the optimal stenting duration of a fully covered self-expandable metal stent (FCSEMS) in a benign biliary stricture. The purpose of this study was to identify the histopathological changes in a bile duct resulting from long-term placement of a FCSEMS.
Methods An FCSEMS was inserted into the common bile duct of 12 canines, and the animals were divided into four groups. Posteuthanasia, necropsy was performed to examine the histopathological changes in the bile ducts after 1, 3, 6, and 9 months.
Results The results of necropsy showed that the covered membranes of the FCSEMSs were intact and easily removed from the bile ducts in 11 of the canines. Severe epithelial hyperplasia of the stented bile duct and epithelial ingrowth into the stent occurred in one animal (from the 3-month group). On histopathological examination, mild inflammatory changes were observed in the stented bile ducts, and there was no significant difference between the four groups. Among the 12 animals, five had
de novo stricture.Conclusions An FCSEMS can be inserted into the bile duct without severe histopathological changes up until 9 months. However, a
de novo stricture and severe epithelial hyperplasia relating to the stent insertion might occur.-
Citations
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