Clinical Endoscopy

Giant Brunner’s Gland Hamartoma of the Duodenal Bulb Presenting with Upper Gastrointestinal Bleeding and Obstruction: Ju Hyoung Lee, Kyeong Min Jo, Tae Oh Kim, Jong Ha Park, Seung Hyun Park, Jae Won Jung, So Chong Hur, Sung Yeun Yang; Clin Endosc 2016;49(6):570-574. Published online October 13, 2016; DOI: https://doi.org/10.5946/ce.2016.022

Brunner’s gland hamartomas are small benign lesions that are most commonly found in the bulb of the duodenum. They are very uncommon, and most are found incidentally during upper gastrointestinal series or esophagogastroduodenoscopy. The lesions tend to be asymptomatic, but patients may present with symptoms of duodenal obstruction or hemorrhage secondary to ulceration. Histologically, a Brunner's gland hamartoma consists of the components of Brunner's gland cells, as well as glandular, adipose and muscle cells. In this study, we report the case of a 30-year-old man who presented with upper gastrointestinal bleeding and obstructive symptoms due to a giant Brunner's gland hamartoma in the duodenal bulb. The hamartoma was successfully removed by endoscopic resection. No significant complications were observed. Microscopically, the lesion was found to be entirely composed of variable Brunner's glands and adipocytes.

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Tracheal Involvement in Crohn Disease: the First Case in Korea: Seunghyun Park, Jongha Park, Hyun-Kuk Kim, Ji Yeon Kim, So Chong Hur, Ju Hyoung Lee, Jae Won Jung, Juwon Lee; Clin Endosc 2016;49(3):310-310. Published online May 24, 2016; DOI: https://doi.org/10.5946/ce.2015.059.e1; Corrects: Clin Endosc 2016;49(2):202

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Tracheal Involvement in Crohn Disease: the First Case in Korea: Seunghyun Park, Jongha Park, Hyun-Kuk Kim, Ji Yeon Kim, So Chong Hur, Ju Hyung Lee, Jae Won Jung, Juwon Lee; Clin Endosc 2016;49(2):202-206. Published online February 16, 2016; DOI: https://doi.org/10.5946/ce.2015.059; Correction in: Clin Endosc 2016;49(3):310

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Respiratory involvement in Crohn disease (CD) is rare condition with only about a dozen reported cases. We report the first case of CD with tracheal involvement in Korea. An 18-year-old woman with CD was hospitalized because of coughing, dyspnea, and fever sustained for 3 weeks. Because she had stridor in her neck, we performed computed tomography of the neck, which showed circumferential wall thickening of the larynx and hypopharynx. Bronchoscopy revealed mucosal irregularity, ulceration, and exudates debris in the proximal trachea, and bronchial biopsy revealed chronic inflammation with granulation tissue. Based on these findings, we suspected CD with tracheal involvement and began administering intravenous methylprednisolone at 1 mg/kg per day, after which her symptoms and bronchoscopic findings improved.

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