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2 "Somashekar G. Krishna"
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Brief Report
Feasibility of single-session endoscopic ultrasound-guided liver biopsy and endoscopic retrograde cholangiopancreatography in liver transplant recipients with abnormal liver function tests
Samuel Han, Sajid Jalil, Jeffery R. Groce, Somashekar G. Krishna, Luis Lara, Peter J. Lee, Georgios I. Papachristou, Khalid Mumtaz
Clin Endosc 2023;56(6):823-826.   Published online March 13, 2023
DOI: https://doi.org/10.5946/ce.2022.134
PDFPubReaderePub

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  • Endoscopic ultrasound guided liver biopsy and portal pressure gradient: when, why and how? Can it become the standard of care in endo-hepatology?
    Jahnvi Dhar, Amit Yadav, Suvradeep Mitra, Zaheer Nabi, Manik Aggarwal, Pankaj Gupta, Antonio Facciorusso, Stefano Francesco Crinò, Guru Trikudanathan, Jayanta Samanta
    Expert Review of Gastroenterology & Hepatology.2025; 19(3): 311.     CrossRef
  • Endoscopic Ultrasound-Guided Liver Biopsy Is Safe and Effective in Post Liver Transplant Patients
    JOSHUA L. HUDSON, AMY BROWNLEE, NEIL D. SHAH, TODD H. BARON
    Techniques and Innovations in Gastrointestinal Endoscopy.2024; 26(4): 359.     CrossRef
  • Insights and perspectives: EUS in post-liver transplantation care
    Eyad Gadour, Bogdan Miutescu, Hussein Hassan Okasha
    Endoscopic Ultrasound.2024; 13(5): 283.     CrossRef
  • Endo-Hepatology: The Buzz Goes Much beyond Liver Biopsy—A Narrative Review
    Rajesh Puri, Zubin Sharma, Swapnil Dhampalwar, Abhishek Kathuria, Bimal Sahu
    Journal of Digestive Endoscopy.2023; 14(04): 227.     CrossRef
  • 2,734 View
  • 120 Download
  • 4 Web of Science
  • 4 Crossref
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Systematic Review and Meta-Analysis
Confocal Laser Endomicroscopy in the Diagnosis of Biliary and Pancreatic Disorders: A Systematic Analysis
Do Han Kim, Somashekar G. Krishna, Emmanuel Coronel, Paul T. Kröner, Herbert C. Wolfsen, Michael B. Wallace, Juan E. Corral
Clin Endosc 2022;55(2):197-207.   Published online November 29, 2021
DOI: https://doi.org/10.5946/ce.2021.079
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic visualization of the microscopic anatomy can facilitate the real-time diagnosis of pancreatobiliary disorders and provide guidance for treatment. This study aimed to review the technique, image classification, and diagnostic performance of confocal laser endomicroscopy (CLE).
Methods
We conducted a systematic review of CLE in pancreatic and biliary ducts of humans, and have provided a narrative of the technique, image classification, diagnostic performance, ongoing research, and limitations.
Results
Probe-based CLE differentiates malignant from benign biliary strictures (sensitivity, ≥89%; specificity, ≥61%). Needlebased CLE differentiates mucinous from non-mucinous pancreatic cysts (sensitivity, 59%; specificity, ≥94%) and identifies dysplasia. Pancreatitis may develop in 2-7% of pancreatic cyst cases. Needle-based CLE has potential applications in adenocarcinoma, neuroendocrine tumors, and pancreatitis (chronic or autoimmune). Costs, catheter lifespan, endoscopist training, and interobserver variability are challenges for routine utilization.
Conclusions
CLE reveals microscopic pancreatobiliary system anatomy with adequate specificity and sensitivity. Reducing costs and simplifying image interpretation will promote utilization by advanced endoscopists.

Citations

Citations to this article as recorded by  
  • Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
    Roxana-Luiza Caragut, Madalina Ilie, Teodor Cabel, Deniz Günșahin, Afrodita Panaitescu, Christopher Pavel, Oana Mihaela Plotogea, Ecaterina Mihaela Rînja, Gabriel Constantinescu, Vasile Sandru
    Diagnostics.2024; 14(5): 490.     CrossRef
  • Endoscopic Ultrasound-Guided Needle-Based Confocal Endomicroscopy as a Diagnostic Imaging Biomarker for Intraductal Papillary Mucinous Neoplasms
    Shreyas Krishna, Ahmed Abdelbaki, Phil A. Hart, Jorge D. Machicado
    Cancers.2024; 16(6): 1238.     CrossRef
  • Exploring Intestinal Permeability: Concept, Diagnosis, Connection to Bowel Disease, and Iron Deficiency
    Olesja Basina, Aleksejs Derovs, Jeļena Derova, Sandra Lejniece
    Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences..2024; 78(4): 244.     CrossRef
  • American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in the diagnosis of malignancy in biliary strictures of undetermined etiology: summary and recommendations
    Larissa L. Fujii-Lau, Nirav C. Thosani, Mohammad Al-Haddad, Jared Acoba, Curtis J. Wray, Rodrick Zvavanjanja, Stuart K. Amateau, James L. Buxbaum, Audrey H. Calderwood, Jean M. Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E. Elhanafi, Douglas S
    Gastrointestinal Endoscopy.2023; 98(5): 685.     CrossRef
  • In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy
    Jina Ko, Kilean Lucas, Rainer Kohler, Elias A. Halabi, Martin Wilkovitsch, Jonathan C. T. Carlson, Ralph Weissleder
    Advanced Science.2022;[Epub]     CrossRef
  • Endoscopic ultrasound-guided tissue acquisition: Needle types, technical issues, and sample handling
    Woo Hyun Paik
    International Journal of Gastrointestinal Intervention.2022; 11(3): 96.     CrossRef
  • 65,535 View
  • 265 Download
  • 5 Web of Science
  • 6 Crossref
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