Over the past year, the novel coronavirus has been a topic of significant research. Multiple gastroenterological symptoms have been associated with this infection, in addition to the well-established pulmonary presentations. Gastrointestinal bleeding can be a complication of infection by severe acute respiratory syndrome coronavirus-2, which can be exacerbated by the anticoagulants used to treat its thrombotic sequelae. We describe the clinical cases of four patients infected with the novel coronavirus, with significant upper gastrointestinal bleeding requiring endoscopic visualization, along with their clinical outcomes.
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