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Case Report
Acquired Hemophilia A with Gastrointestinal Bleeding
Narae Park, Jin Seok Jang, Jae Hwang Cha
Clin Endosc 2020;53(1):90-93.   Published online July 8, 2019
DOI: https://doi.org/10.5946/ce.2019.036
AbstractAbstract PDFPubReaderePub
Peptic ulcer disease is the most common cause of acute gastrointestinal bleeding, followed by variceal bleeding, Mallory–Weiss syndrome, and malignancy. On the contrary, acquired hemophilia A is a very rare hemorrhagic disease, which usually manifests with musculocutaneous bleeding, caused by autoantibodies against coagulation factor VIII.
A 78-year-old man presented to the Emergency Department with melena. Dieulafoy’s lesions were observed on esophagogastroduodenoscopy, and endoscopic cauterization was performed. However, the patient complained of back pain and symptoms indicative of upper gastrointestinal bleeding. Abdominopelvic computed tomography was performed, and hematoma in the psoas muscle was detected. Antibodies against coagulation factor VIII were confirmed with a blood test, and the diagnosis of acquired hemophilia A was made. Here, we report a case of acquired hemophilia A presenting with upper gastrointestinal bleeding symptoms and present a brief review of literature.

Citations

Citations to this article as recorded by  
  • Variceal hemorrhage in a patient with cirrhosis and congenital hemophilia A: A therapeutic challenge
    Rafael Gregorio Peña Amaya, María del Carmen Figueredo Peña
    SAGE Open Medical Case Reports.2024;[Epub]     CrossRef
  • Acquired hemophilia A as a disease of the elderly: A comprehensive review of epidemiology, pathogenesis, and novel therapy
    Andrea Lehoczki, Mónika Fekete, Gábor Mikala, Imre Bodó
    GeroScience.2024; 47(1): 503.     CrossRef
  • A case of refractory bleeding from duodenal angioectasia with acquired hemophilia A
    Hiroko Abe, Masahiro Saito, Kaname Uno, Tomoyuki Koike, Satoshi Ichikawa, Masashi Saito, Takeshi Kanno, Waku Hatta, Naoki Asano, Atsushi Masamune
    Clinical Journal of Gastroenterology.2023; 16(3): 355.     CrossRef
  • C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians
    Dimitra S. Mouliou
    Diseases.2023; 11(4): 132.     CrossRef
  • THE RESTRICTIVE EFFECTS OF THE COVID-19 PANDEMIC ON THE MANAGEMENT OF PLASTRON APPENDICITIS IN A KNOWN HEMOPHILIA A PATIENT
    Mert Yurtsever, İrfan Arda Aykut, Beste Girgin, Berkay Aldemir, Oğuzhan Alp Öztürk, Zeliha Türkyılmaz
    TURKISH MEDICAL STUDENT JOURNAL.2022; 9(3): 84.     CrossRef
  • A rare cause of lower gastrointestinal bleeding: acquired hemophilia A
    Pilar Del Pino Bellido, María Fernanda Guerra Veloz, Reyes Aparcero López
    Revista Española de Enfermedades Digestivas.2021;[Epub]     CrossRef
  • Undiagnosed Acquired Hemophilia A: Presenting as Recurrent Gastrointestinal Bleeding
    Arya Mariam Roy, Aisha Siddiqui, Anand Venkata
    Cureus.2020;[Epub]     CrossRef
  • 5,790 View
  • 160 Download
  • 6 Web of Science
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Inflammatory Pseudotumor Causing Small Bowel Obstruction in a Patient with AIDS
Hyun Soo Kim, M.D., Jae Myung Cha, M.D., Joung Il Lee, M.D., Kwang Ro Joo, M.D., Hyun Joon Jung, M.D., Chi Hoon Lee, M.D., Sung-Jig Lim, M.D.* and Ki Yong Na, M.D.*
Korean J Gastrointest Endosc 2011;42(4):250-254.   Published online April 28, 2011
AbstractAbstract PDF
Small bowel obstructions are most commonly caused by adhesions, hernias, neoplasms or inflammatory stricture. Inflammatory pseudotumors are an uncommon cause of small bowel obstruction, even in a patient with acquired immunodeficiency syndrome (AIDS). We have experienced a case of small bowel obstruction caused by an inflammatory pseudotumor in a 38-year old male with AIDS. Abdominal computed tomography showed small bowel obstruction due to jejunal annular wall thickening. Surgical laparotomy showed a non-specific granulomatous inflammatory mass that could not fulfill any diagnostic criteria for a specific disease. This report describes our findings of small bowel obstruction due to an inflammatory pseudotumor and discusses the differential diagnosis of inflammatory pseudotumor in AIDS patients. (Korean J Gastrointest Endosc 2011;42:250-254)
  • 2,189 View
  • 8 Download
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