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Original Articles
A retrospective study on the comparative use of fine-needle biopsy and aspiration for the diagnosis and classification of malignant lymphoma in Japan
Fumitaka Niiya, Akihiro Nakamura, Yasuo Ueda, Takafumi Ogawa, Naoki Tamai, Masataka Yamawaki, Jun Noda, Tetsushi Azami, Yuichi Takano, Masatsugu Nagahama
Received November 28, 2024  Accepted February 9, 2025  Published online May 27, 2025  
DOI: https://doi.org/10.5946/ce.2024.320    [Epub ahead of print]
Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is essential for diagnosing malignant lymphoma (ML). However, the optimal needle type for maximizing the diagnostic yield and tissue quality remains unclear. We compared the diagnostic performance and histological tissue quality between fine-needle biopsy (FNB) and fine-needle aspiration (FNA) needles in EUS-TA for ML.
Methods
This retrospective study included patients who underwent EUS-TA for suspected ML. The diagnostic accuracy, histological sample quality assessed by scoring, and adverse events were compared between the FNB and FNA groups. A subgroup analysis was performed for 22-gauge needles.
Results
FNB demonstrated higher diagnostic accuracy (75%) than FNA (50%) for cytology, with 100% sensitivity for histological diagnosis compared with 78.9% for FNA. The FNB group had significantly higher diagnostic rates for the World Health Organization subclassification of ML (71.4% vs. 31.6%, p=0.037). Additionally, FNB obtained superior histological quality, with 71.4% of samples scoring 5 compared with 41.2% in the FNA group. Adverse events were minimal in both groups.
Conclusions
EUS-FNB showed better diagnostic performance and histological tissue quality than EUS-FNA for ML, particularly in obtaining adequate samples for histological evaluation and subclassification. Therefore, EUS-FNB can be safely performed. Future research with larger sample sizes and genetic testing is warranted.
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Predictive factors for the diagnosis of autoimmune pancreatitis using endoscopic ultrasound-guided tissue acquisition: a retrospective study in Japan
Keisuke Yonamine, Shinsuke Koshita, Yoshihide Kanno, Takahisa Ogawa, Hiroaki Kusunose, Toshitaka Sakai, Kazuaki Miyamoto, Fumisato Kozakai, Haruka Okano, Yuto Matsuoka, Kento Hosokawa, Hidehito Sumiya, Yutaka Noda, Kei Ito
Clin Endosc 2025;58(3):457-464.   Published online March 28, 2025
DOI: https://doi.org/10.5946/ce.2024.238
Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReaderePub
Background
/Aims: The factors affecting the detection rate of lymphoplasmacytic sclerosing pancreatitis (LPSP) using endoscopic ultrasound-guided tissue acquisition (EUS-TA) in patients with type 1 autoimmune pancreatitis (AIP) have not been thoroughly studied. Therefore, we conducted a retrospective study to identify the predictive factors for histologically detecting level 1 or 2 LPSP using EUS-TA.
Methods
Fifty patients with AIP were included in this study, and the primary outcome measures were the predictive factors for histologically detecting level 1 or 2 LPSP using EUS-TA.
Results
Multivariate analysis identified the use of fine needle biopsy (FNB) needles as a significant predictive factor for LPSP detection (odds ratio, 15.1; 95% confidence interval, 1.62–141; ¬¬p=0.017). The rate of good-quality specimens (specimen adequacy score ≥4) was significantly higher for the FNB needle group than for the fine needle aspiration (FNA) needle group (97% vs. 56%; p<0.01), and the FNB needle group required significantly fewer needle passes than the FNA needle group (median, 2 vs. 3; p<0.01).
Conclusions
The use of FNB needles was the most important factor for the histological confirmation of LPSP using EUS-TA in patients with type 1 AIP.

Citations

Citations to this article as recorded by  
  • A new era for autoimmune pancreatitis diagnosis: fine-needle biopsy outperforms fine-needle aspiration in endoscopic ultrasound-guided tissue acquisition
    Gunn Huh, Tae Jun Song
    Clinical Endoscopy.2025; 58(3): 406.     CrossRef
  • 786 View
  • 137 Download
  • 1 Web of Science
  • 1 Crossref
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In-room cytologic evaluation by trained endosonographer for determination of procedure end in endoscopic ultrasound-guided fine needle biopsy of solid pancreatic lesions: a prospective study in Taiwan
Weng-Fai Wong, Yu-Ting Kuo, Wern-Cherng Cheng, Chia-Tung Shun, Ming-Lun Han, Chieh-Chang Chen, Hsiu-Po Wang
Clin Endosc 2025;58(3):465-473.   Published online December 12, 2024
DOI: https://doi.org/10.5946/ce.2024.143
Graphical AbstractGraphical Abstract AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) is an essential tool for tissue acquisition in solid pancreatic tumors. Rapid on-site evaluation (ROSE) by cytologists ensures diagnostic accuracy. However, the universal application of the ROSE is limited by its availability. Therefore, we aimed to investigate the feasibility of determining the end of the procedure based on the results of in-room cytological evaluation by trained endosonographers (IRCETE).
Methods
A training course focusing on the cytological interpretation of common pancreatic tumors was provided to the three endosonographers. After training, the decision to terminate EUS-FNB was made based on IRCETE results. The diagnostic accuracy, concordance rate of diagnostic categories, and sample adequacy were compared with those determined by board-certified cytologists and macroscopic on-site evaluation (MOSE).
Results
We enrolled 65 patients with solid pancreatic tumors, most of whom were malignant (86.2%). The diagnostic accuracy was 90.8% when the end of the procedure was determined based on IRCETE, compared to 87.7% and 98.5% when determined by MOSE and cytologists, respectively (p=0.060). Based on the cytologists’ results, the accuracy of IRCETE in diagnostic category interpretation was 97.3%.
Conclusions
In the absence of ROSE, IRCETE can serve as a supplementary alternative to MOSE in determining the end of tissue sampling with a high accuracy rate.

Citations

Citations to this article as recorded by  
  • Diagnostic accuracy and sensitivity of the rapid on-site evaluation (ROSE) versus macroscopic on-site evaluation (MOSE) in endoscopic ultrasound (EUS)-guided sampling: a systematic review
    Eyad Gadour, Bogdan Miutescu, Sarah Al Ghamdi, Calin Burciu, Hossam Shaaban, Deiana Vuletici, Aymen Almuhaidb, Iulia Ratiu, Emad Aljahdli, Hussein Okasha
    Frontline Gastroenterology.2025; : flgastro-2024-102918.     CrossRef
  • 1,460 View
  • 233 Download
  • 1 Web of Science
  • 1 Crossref
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Clinical utility of endoscopic ultrasound-guided tissue acquisition for comprehensive genomic profiling of patients with biliary tract cancer, especially with intrahepatic cholangiocarcinoma
Takafumi Yanaidani, Kazuo Hara, Nozomi Okuno, Shin Haba, Takamichi Kuwahara, Yasuhiro Kuraishi, Nobumasa Mizuno, Sho Ishikawa, Masanori Yamada, Tsukasa Yasuda
Clin Endosc 2024;57(3):384-392.   Published online February 15, 2024
DOI: https://doi.org/10.5946/ce.2023.139
Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is a standard diagnostic method for biliary tract cancer (BTC), and samples obtained in this manner may be used for comprehensive genomic profiling (CGP). This study evaluated the utility of EUS-TA for CGP in a clinical setting and determined the factors associated with the adequacy of CGP in patients with BTC.
Methods
CGP was attempted for 105 samples from 94 patients with BTC at the Aichi Cancer Center, Japan, from October 2019 to April 2022.
Results
Overall, 77.1% (81/105) of the samples were adequate for CGP. For 22-G or 19-G fine-needle biopsy (FNB), the sample adequacy was 85.7% (36/42), which was similar to that of surgical specimens (94%, p=0.45). Univariate analysis revealed that 22-G or larger FNB needle usage (86%, p=0.003), the target primary lesions (88%, p=0.015), a target size ≥30 mm (100%, p=0.0013), and number of punctures (90%, p=0.016) were significantly positively associated with CGP sample adequacy.
Conclusions
EUS-TA is useful for CGP tissue sampling in patients with BTC. In particular, the use of 22-G or larger FNB needles may allow for specimen adequacy comparable to that of surgical specimens.

Citations

Citations to this article as recorded by  
  • Adequacy evaluation of 22‐gauge needle endoscopic ultrasound‐guided tissue acquisition samples and glass slides preparation for successful comprehensive genomic profiling testing: A single institute experience
    Tami Nagatani, Yoji Wani, Masahiro Takatani, Soichiro Fushimi, Hirofumi Inoue, Shinichiro Hori, Kyohei Kai, Hideki Yamamoto, Tetsuya Okazaki, Maki Tanioka, Hiroyuki Okada, Akira Hirasawa
    DEN Open.2026;[Epub]     CrossRef
  • A rare case of needle tract seeding following endoscopic ultrasound‐guided tissue acquisition for cholangiocarcinoma
    Tatsunori Satoh, Haruna Takahashi, Shinya Kawaguchi
    Journal of Hepato-Biliary-Pancreatic Sciences.2025;[Epub]     CrossRef
  • Is genomic analysis possible in a tissue acquired via endoscopic ultrasound-guided fine-needle biopsy in cholangiocarcinoma?
    Jonghyun Lee, Sung Yong Han
    Clinical Endoscopy.2024; 57(3): 332.     CrossRef
  • Utility of Transpapillary Biopsy and Endoscopic Ultrasound-Guided Tissue Acquisition for Comprehensive Genome Profiling of Unresectable Biliary Tract Cancer
    Soma Fukuda, Susumu Hijioka, Yoshikuni Nagashio, Daiki Yamashige, Daiki Agarie, Yuya Hagiwara, Kohei Okamoto, Shin Yagi, Yasuhiro Komori, Masaru Kuwada, Yuta Maruki, Chigusa Morizane, Hideki Ueno, Nobuyoshi Hiraoka, Kiichiro Tsuchiya, Takuji Okusaka
    Cancers.2024; 16(16): 2819.     CrossRef
  • Endoscopic Ultrasound and Intraductal Ultrasound in the Diagnosis of Biliary Tract Diseases: A Narrative Review
    Akiya Nakahata, Yasunobu Yamashita, Masayuki Kitano
    Diagnostics.2024; 14(18): 2086.     CrossRef
  • 3,782 View
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  • 5 Web of Science
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The role of needle-based confocal laser endomicroscopy in the diagnosis of pancreatic neuroendocrine tumors
Masanori Yamada, Kazuo Hara, Nobumasa Mizuno, Shin Haba, Takamichi Kuwahara, Nozomi Okuno, Yasuhiro Kuraishi, Takafumi Yanaidani, Sho Ishikawa, Tsukasa Yasuda, Toshitaka Fukui
Clin Endosc 2024;57(3):393-401.   Published online September 12, 2023
DOI: https://doi.org/10.5946/ce.2023.068
Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a highly accurate method for diagnosing pancreatic neuroendocrine tumors (PNETs); however, some PNETs are difficult to diagnose. Recently, the efficacy of needle-based confocal laser endomicroscopy (nCLE) in diagnosing solid pancreatic masses has been reported. However, the efficacy of nCLE in the diagnosis of PNETs remains unknown and only a small number of cases have been reported. Hence, this study aimed to evaluate the efficacy of nCLE in the diagnosis of PNETs.
Methods
This single-center retrospective study evaluated 30 consecutive patients with suspected PNETs on contrast-enhanced computed tomography, who consented to nCLE combined with EUS-FNA and were diagnosed using EUS-FNA or surgical resection. The diagnostic criteria for PNETs using nCLE were based on the nesting and trabecular and glandular arrangement of tumor cell clusters surrounded by capillary vessels and fibrosis, as reported in previous studies.
Results
The diagnosis using nCLE was classified into three categories: misdiagnosis in three cases (10%), non-diagnostic in six cases (20%), and diagnostic in 21 cases (70%). nCLE was able to diagnose PNET in one of the two cases with inconclusive EUS-FNA.
Conclusions
Although further development of the resolution and optimization of the diagnostic criteria are required, nCLE may constitute a useful diagnostic option in cases of inconclusive EUS-FNA for PNETs.

Citations

Citations to this article as recorded by  
  • Recent developments in the diagnosis of pancreatic neuroendocrine neoplasms
    Anna Battistella, Matteo Tacelli, Paola Mapelli, Marco Schiavo Lena, Valentina Andreasi, Luana Genova, Francesca Muffatti, Francesco De Cobelli, Stefano Partelli, Massimo Falconi
    Expert Review of Gastroenterology & Hepatology.2024; 18(4-5): 155.     CrossRef
  • Advancements and challenges in gastrointestinal imaging
    Eun Jeong Gong, Chang Seok Bang
    World Journal of Clinical Cases.2024; 12(33): 6591.     CrossRef
  • 3,459 View
  • 141 Download
  • 1 Web of Science
  • 2 Crossref
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A multicenter comparative study of endoscopic ultrasound-guided fine-needle biopsy using a Franseen needle versus conventional endoscopic ultrasound-guided fine-needle aspiration to evaluate microsatellite instability in patients with unresectable pancreatic cancer
Tadayuki Takagi, Mitsuru Sugimoto, Hidemichi Imamura, Yosuke Takahata, Yuki Nakajima, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Yuki Sato, Hiroki Irie, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Yuko Hashimoto, Goro Shibukawa, Shigeru Marubashi, Takuto Hikichi, Hiromasa Ohira
Clin Endosc 2023;56(1):107-113.   Published online January 16, 2023
DOI: https://doi.org/10.5946/ce.2022.019
AbstractAbstract PDFPubReaderePub
Background
/Aims: Immune checkpoint blockade has recently been reported to be effective in treating microsatellite instability (MSI)-high tumors. Therefore, sufficient sampling of histological specimens is necessary in cases of unresectable pancreatic cancer (UR-PC). This multicenter study investigated the efficacy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needle for MSI evaluation in patients with UR-PC.
Methods
A total of 89 patients with UR-PC who underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or EUS-FNB using 22-G needles at three hospitals in Japan (2018–2021) were enrolled. Fifty-six of these patients (FNB 23 and FNA 33) were followed up or evaluated for MSI. Patient characteristics, UR-PC data, and procedural outcomes were compared between patients who underwent EUS-FNB and those who underwent EUS-FNA.
Results
No significant difference in terms of sufficient tissue acquisition for histology was observed between patients who underwent EUS-FNB and those who underwent EUS-FNA. MSI evaluation was possible significantly more with tissue samples obtained using EUS-FNB than with tissue samples obtained using EUS-FNA (82.6% [19/23] vs. 45.5% [15/33], respectively; p<0.01). In the multivariate analysis, EUS-FNB was the only significant factor influencing the possibility of MSI evaluation.
Conclusions
EUS-FNB using a Franseen needle is desirable for ensuring sufficient tissue acquisition for MSI evaluation.

Citations

Citations to this article as recorded by  
  • Lymphadenopathy Tissue Sampling by EUS-Guided Fine-Needle Biopsy Contributes to Meeting the Conditions for Genomic Profiling
    Mitsuru Sugimoto, Tadayuki Takagi, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Yuki Sato, Hiroki Irie, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira
    Journal of Clinical Gastroenterology.2025; 59(4): 369.     CrossRef
  • Adverse events of 20–22G second‐generation endoscopic ultrasound‐guided fine‐needle biopsy needles for solid lesions in the upper gastrointestinal tract and adjacent organs: Systematic review and meta‐analysis
    Cheng‐ye Pan, Shi‐min Wang, Dong‐hao Cai, Jia‐yi Ma, Shi‐yu Li, Yibin Guo, Sun Jing, Jin Zhendong, Kaixuan Wang
    Digestive Endoscopy.2025; 37(5): 490.     CrossRef
  • Benefits of macroscopic on-site evaluation in endoscopic ultrasound-guided tissue acquisition for comprehensive genomic profiling
    Junya Sato, Hirotoshi Ishiwatari, Kazuma Ishikawa, Hiroki Sakamoto, Takuya Doi, Masahiro Yamamura, Kazunori Takada, Yoichi Yamamoto, Masao Yoshida, Sayo Ito, Noboru Kawata, Kenichiro Imai, Kinichi Hotta, Hiroyuki Ono
    Endoscopy International Open.2025;[Epub]     CrossRef
  • Oil blotting paper for formalin fixation increases endoscopic ultrasound‐guided tissue acquisition‐collected sample volumes on glass slides
    Takuo Yamai, Kenji Ikezawa, Yusuke Seiki, Ko Watsuji, Yasuharu Kawamoto, Takeru Hirao, Kazuma Daiku, Shingo Maeda, Makiko Urabe, Yugo Kai, Ryoji Takada, Kaori Mukai, Tasuku Nakabori, Hiroyuki Uehara, Sayoko Tsuzaki, Ayumi Ryu, Satoshi Tanada, Shigenori Na
    Cancer Medicine.2024;[Epub]     CrossRef
  • MSI-H Detection by ddPCR in Endoscopic Ultrasound Fine Needle Biopsy (EUS-FNB) from Pancreatic Ductal Adenocarcinoma
    Maria Assunta Piano, Elisa Boldrin, Lidia Moserle, Nicoletta Salerno, Dalila Fanelli, Giulia Peserico, Maria Raffaella Biasin, Giovanna Magni, Veronica Varano, Giorgia Zalgelli, Vasileios Mourmouras, Antonio Rosato, Antonio Scapinello, Alberto Fantin, Mat
    International Journal of Molecular Sciences.2024; 25(20): 11090.     CrossRef
  • 3,409 View
  • 156 Download
  • 5 Web of Science
  • 5 Crossref
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Comparison of diagnostic performances of slow-pull suction and standard suction in endoscopic ultrasound-guided fine needle biopsy for gastrointestinal subepithelial tumors
Joon Seop Lee, Chang Min Cho, Yong Hwan Kwon, An Na Seo, Han Ik Bae, Man-Hoon Han
Clin Endosc 2022;55(5):637-644.   Published online August 17, 2022
DOI: https://doi.org/10.5946/ce.2021.257
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is integral to the diagnosis of gastrointestinal (GI) subepithelial tumors (SETs). The impact of different EUS-FNB tissue sampling techniques on specimen adequacy and diagnostic accuracy in SETs has not been fully evaluated. This study aimed to compare the diagnostic outcomes of slow-pull (SP) and standard suction (SS) in patients with GI SETs.
Methods
In this retrospective comparative study, 54 patients were enrolled. Medical records were reviewed for location and size of the target lesion, FNB needle type/size, technical order, specimen adequacy, diagnostic yield, and adverse events. The acquisition rate of adequate specimens and diagnostic accuracy were compared according to EUS-FNB techniques.
Results
The mean lesion size was 42.6±36.4 mm, and most patients were diagnosed with GI stromal tumor (75.9%). The overall diagnostic accuracies of the SP and SS techniques were 83.3% and 81.5%, respectively (p=0.800). The rates of obtaining adequate core tissue were 79.6% and 75.9%, respectively (p=0.799). No significant clinical factors affected the rate of obtaining adequate core tissue, including lesion location and size, FNB needle size, and final diagnosis.
Conclusions
SP and SS had comparable diagnostic accuracies and adequate core tissue acquisition for GI SETs via EUS-FNB.

Citations

Citations to this article as recorded by  
  • Advancements in endoscopic resection of subepithelial tumors: toward safer, recurrence-free techniques
    Won Shik Kim, Moon Kyung Joo
    Clinical Endoscopy.2025; 58(2): 256.     CrossRef
  • Current Practices in Histological Diagnosis and Management of Asymptomatic Gastric Subepithelial Lesions: A Multicenter Survey in Korea
    Sang Hoon Kim, Jae Yong Park, Ayoung Lee, Bong Eun Lee, Byung-Hoon Min, Chan Hyuk Park, Da Hyun Jung, Hyeong Ho Jo, Hyunsoo Chung, In Hyuk Yoo, Seon Young Park, Seung-Woo Lee, Yonghoon Choi, Jeong Hoon Lee, Seung Han Kim, Jae Myung Park, Joon Sung Kim, Su
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2025; 25(2): 159.     CrossRef
  • Endoscopic ultrasound-guided fine-needle aspiration for gastrointestinal subepithelial lesions
    Takuto Hikichi, Minami Hashimoto, Takumi Yanagita, Tsunetaka Kato, Jun Nakamura
    Journal of Medical Ultrasonics.2024; 51(2): 195.     CrossRef
  • What method can we choose if rapid on-site evaluation is not available for the endoscopic ultrasound-guided tissue acquisition of upper gastrointestinal subepithelial lesions?
    Yu Kyung Cho
    Clinical Endoscopy.2024; 57(1): 53.     CrossRef
  • The Diagnostic Approach of Benign Esophageal Tumors: A Narrative Review
    Alex R. Jones, Preksha Vankawala, Tarek Sawas
    Current Treatment Options in Gastroenterology.2024; 22(2): 44.     CrossRef
  • Diagnostic yield of endoscopic and EUS-guided biopsy techniques in subepithelial lesions of the upper GI tract: a systematic review
    Cynthia A. Verloop, Jacqueline A.C. Goos, Marco J. Bruno, Rutger Quispel, Lydi M.J.W. van Driel, Lieke Hol
    Gastrointestinal Endoscopy.2024; 99(6): 895.     CrossRef
  • EUS‐guided tissue acquisition from gastric subepithelial lesions—The optimal technique still remains undecided
    Suprabhat Giri, Sridhar Sundaram
    Australasian Journal of Ultrasound in Medicine.2024; 27(4): 263.     CrossRef
  • An Esophageal Leiomyoma with Cystic Degeneration Mimicking a Malignant Neoplasm
    Gwang Ha Kim, Dong Chan Joo, Moon Won Lee, Bong Eun Lee, Kyungbin Kim
    The Ewha Medical Journal.2023;[Epub]     CrossRef
  • Prevalence, natural progression, and clinical practices of upper gastrointestinal subepithelial lesions in Korea: a multicenter study
    Younghee Choe, Yu Kyung Cho, Gwang Ha Kim, Jun-Ho Choi, Eun Soo Kim, Ji Hyun Kim, Eun Kwang Choi, Tae Hyeon Kim, Seong-Hun Kim, Do Hoon Kim
    Clinical Endoscopy.2023; 56(6): 744.     CrossRef
  • 3,751 View
  • 141 Download
  • 6 Web of Science
  • 9 Crossref
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Systematic Review and Meta-Analysis
Mucosal incision-assisted biopsy versus endoscopic ultrasound-assisted tissue acquisition for subepithelial lesions: a systematic review and meta-analysis
Suprabhat Giri, Shivaraj Afzalpurkar, Sumaswi Angadi, Sridhar Sundaram
Clin Endosc 2022;55(5):615-625.   Published online August 4, 2022
DOI: https://doi.org/10.5946/ce.2022.133
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background
/Aims: Mucosal incision-assisted biopsy (MIAB) for tissue acquisition (TA) from subepithelial lesions (SELs) is emerging as an alternative to endoscopic ultrasound (EUS)-guided TA. Only a limited number of studies compared the diagnostic utility of MIAB and EUS for upper gastrointestinal (GI) SELs; therefore, we conducted this systematic review and meta-analysis.
Methods
A comprehensive literature search from January 2020 to January 2022 was performed to compare the diagnostic accuracy and safety of MIAB and EUS-guided TA for upper GI SELs.
Results
Seven studies were included in this meta-analysis. The pooled technical success rate (risk ratio [RR], 0.96; 95% confidence interval [CI], 0.89–1.04) and procedural time (mean difference=–4.53 seconds; 95% CI, –22.38 to 13.31] were comparable between both the groups. The overall chance of obtaining a positive diagnostic yield was lower with EUS than with MIAB for all lesions (RR, 0.83; 95% CI, 0.71–0.98) but comparable when using a fine-needle biopsy needle (RR, 0.93; 95% CI, 0.83–1.04). The positive diagnostic yield of MIAB was higher for lesions <20 mm (RR, 0.75; 95% CI, 0.63–0.89). Six studies reported no adverse events.
Conclusions
MIAB can be considered an effective alternative to EUS-guided TA for upper GI SELs without an increased risk of adverse events.

Citations

Citations to this article as recorded by  
  • Diagnostic ability and adverse events of mucosal incision‐assisted biopsy for gastric subepithelial tumors: Systematic review and meta‐analysis
    Eriko Koizumi, Osamu Goto, Akihisa Matsuda, Toshiaki Otsuka, Yumiko Ishikawa, Shun Nakagome, Masahiro Niikawa, Tsugumi Habu, Keiichiro Yoshikata, Kumiko Kirita, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Jun Omori, Naohiko Akimoto, Hiroshi Yoshida, Kat
    Digestive Endoscopy.2025; 37(3): 236.     CrossRef
  • Current Management Strategies for Patients with Gastrointestinal and Pulmonary Neuroendocrine Tumors
    Yulia V. Mikheeva, Pavel O. Rumyantsev, Konstantin K. Puzakov, Konstantin Yu. Slashchuk, Daniil D. Omelchuk, Anastasia V. Potapenko, Sergey P. Medvedev
    Russian Journal of Oncology.2025; 30(1): 41.     CrossRef
  • Approach to upper gastrointestinal subepithelial lesions
    Shrihari Anil Anikhindi, Rajesh Puri, Noriya Uedo, Kamlesh Taori, Anil Arora
    Expert Review of Gastroenterology & Hepatology.2025;[Epub]     CrossRef
  • Diagnostic challenges of inflammatory submucosal tumor-like lesions: a multicenter propensity score-matching analysis
    Mengting Yu, Jiao Li, Yongfeng Yan, Xiaoxiang Wang, Yanhui Mao, Dandan Jiang, Zhengkui Zhou, Yuanyuan Chen, Xiaobin Sun
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Technical outcomes and postprocedural courses of mucosal incision‐assisted biopsy for possible gastric gastrointestinal stromal tumors: A series of 48 cases (with video)
    Eriko Koizumi, Osamu Goto, Shun Nakagome, Tsugumi Habu, Yumiko Ishikawa, Kumiko Kirita, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Teppei Akimoto, Jun Omori, Naohiko Akimoto, Katsuhiko Iwakiri
    DEN Open.2024;[Epub]     CrossRef
  • The Diagnostic Approach of Benign Esophageal Tumors: A Narrative Review
    Alex R. Jones, Preksha Vankawala, Tarek Sawas
    Current Treatment Options in Gastroenterology.2024; 22(2): 44.     CrossRef
  • Unroofing of subepithelial lesions in the upper gastrointestinal tract using cold snare: an easy and efficient technique for diagnosis
    Bernhard Morell, Frans Olivier The, Christoph Gubler, Fritz Ruprecht Murray
    Clinical Endoscopy.2024; 57(2): 274.     CrossRef
  • Diagnostic yield of endoscopic and EUS-guided biopsy techniques in subepithelial lesions of the upper GI tract: a systematic review
    Cynthia A. Verloop, Jacqueline A.C. Goos, Marco J. Bruno, Rutger Quispel, Lydi M.J.W. van Driel, Lieke Hol
    Gastrointestinal Endoscopy.2024; 99(6): 895.     CrossRef
  • Small gastric subepithelial lesions: A sand in the eye
    Tanyaporn Chantarojanasiri, Nikhil Sonthalia, Rashid N. Lui
    Journal of Gastroenterology and Hepatology.2024; 39(7): 1207.     CrossRef
  • EUS‐guided tissue acquisition from gastric subepithelial lesions—The optimal technique still remains undecided
    Suprabhat Giri, Sridhar Sundaram
    Australasian Journal of Ultrasound in Medicine.2024; 27(4): 263.     CrossRef
  • Endoscopic Ultrasound and Gastric Sub-Epithelial Lesions: Ultrasonographic Features, Tissue Acquisition Strategies, and Therapeutic Management
    Marzia Varanese, Marco Spadaccini, Antonio Facciorusso, Gianluca Franchellucci, Matteo Colombo, Marta Andreozzi, Daryl Ramai, Davide Massimi, Roberto De Sire, Ludovico Alfarone, Antonio Capogreco, Roberta Maselli, Cesare Hassan, Alessandro Fugazza, Alessa
    Medicina.2024; 60(10): 1695.     CrossRef
  • Efficacy of EUS-guided keyhole biopsies in diagnosing subepithelial lesions of the upper gastrointestinal tract
    Sen Verhoeve, Cynthia Verloop, Marco Bruno, Valeska Terpstra, Lydi Van Driel, Lars Perk, Lieke Hol
    Endoscopy International Open.2024; 12(10): E1183.     CrossRef
  • Approach to Small Gastric Subepithelial Lesions
    Moon Won Lee, Bong Eun Lee
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(1): 28.     CrossRef
  • Is the canalization to obtain deep biopsy of gastrointestinal subepithelial tumors miniprobe-guidded as an alternative to conventional known techniques?
    Modesto Varas Lorenzo, Ramón Abad Belando
    Revista Española de Enfermedades Digestivas.2023;[Epub]     CrossRef
  • Role of Advanced Gastrointestinal Endoscopy in the Comprehensive Management of Neuroendocrine Neoplasms
    Harishankar Gopakumar, Vinay Jahagirdar, Jagadish Koyi, Dushyant Singh Dahiya, Hemant Goyal, Neil R. Sharma, Abhilash Perisetti
    Cancers.2023; 15(16): 4175.     CrossRef
  • 4,108 View
  • 154 Download
  • 11 Web of Science
  • 15 Crossref
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Original Articles
Comparison of tube-assisted mapping biopsy with digital single-operator peroral cholangioscopy for preoperative evaluation of biliary tract cancer
Tsuyoshi Takeda, Takashi Sasaki, Takafumi Mie, Takeshi Okamoto, Chinatsu Mori, Takaaki Furukawa, Yuto Yamada, Akiyoshi Kasuga, Masato Matsuyama, Masato Ozaka, Naoki Sasahira
Clin Endosc 2022;55(4):549-557.   Published online July 20, 2022
DOI: https://doi.org/10.5946/ce.2021.227
AbstractAbstract PDFPubReaderePub
Background
/Aims: Digital single-operator cholangioscopy (DSOC)-guided mapping biopsy (DMB) and tube-assisted mapping biopsy (TMB) are two techniques used for preoperative evaluation of biliary tract cancer (BTC). However, data regarding the diagnostic performance of these techniques are limited.
Methods
We retrospectively examined consecutive patients with BTC who underwent either technique at our institution between 2018 and 2020. We evaluated the technical success rate, adequate tissue acquisition rate, and diagnostic performance of these techniques for the evaluation of lateral spread of BTC.
Results
A total of 54 patients were included in the study. The technical success rate of reaching the target sites was 95% for DMB and 100% for TMB. The adequate tissue acquisition rate was 61% for DMB and 69% for TMB. The adequate tissue acquisition rate was low, especially for target sites beyond the secondary biliary radicles. The sensitivity of DMB alone was 39%, which improved to 65% when combined with visual impression. Experts demonstrated a higher negative predictive value and diagnostic accuracy with respect to both DSOC visual impression and DMB for the evaluation of lateral spread of BTC compared to trainees.
Conclusions
Adequate tissue acquisition rates were similar between the two techniques. Since DMB requires expertise, TMB may be an acceptable option when DSOC is unavailable or when DSOC expertise is limited.

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  • Usefulness of a novel 11F digital single‐operator cholangioscopy through a colonoscope in a patient with surgically altered anatomy
    Takafumi Mie, Tsuyoshi Takeda, Takashi Sasaki
    Digestive Endoscopy.2025; 37(4): 438.     CrossRef
  • Endoscopic evaluation of indeterminate biliary strictures: Cholangioscopy, endoscopic ultrasound, or both?
    Raymond S. Y. Tang
    Digestive Endoscopy.2024; 36(7): 778.     CrossRef
  • Cholangioscopy for biliary diseases
    Aymeric Becq, Adil Soualy, Marine Camus
    Current Opinion in Gastroenterology.2023; 39(2): 67.     CrossRef
  • 3,718 View
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Confirming Whether Fine Needle Biopsy Device Shortens the Learning Curve of Endoscopic Ultrasound-Guided Tissue Acquisition Without Rapid Onsite Evaluation
Meng-Ying Lin, Cheng-Lin Wu, Mitsuhiro Kida, Wei-Lun Chang, Bor-Shyang Sheu
Clin Endosc 2021;54(3):420-427.   Published online May 28, 2021
DOI: https://doi.org/10.5946/ce.2020.184
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasonography (EUS)-guided tissue acquisition requires a long learning curve. We aimed to compare the skill maturation curves between fine needle aspiration (FNA) and biopsy (FNB) for tissue acquisition.
Methods
The initial 60 procedures performed by the trainee endosonographer (30 FNA vs. 30 FNB) were consecutively enrolled. The difference in procedure performance was compared between the two groups. Learning curves were assessed. Twenty additional cases were subsequently enrolled to assess the consistency of performance in the FNB group.
Results
The FNB group acquired larger tissue samples (2.35 vs. 0.70 mm2; p<0.001) with lower blood content (p=0.001) and higher tissue quality (p=0.017) compared with the FNA group. In addition, the FNB group required less needle pass to establish a diagnosis (2.43 vs. 2.97; p=0.006). A threshold diagnostic sensitivity of ≥80% was achieved after performing 10 FNB procedures. The number of needle passes significantly decreased after conducting 20 FNB procedures (1.80 vs. 2.70; p=0.041). The diagnostic sensitivity and number of needle passes remained the same in the subsequent FNB procedures. By contrast, this skill maturation phenomenon was not observed after performing 30 FNA procedures.
Conclusions
In EUS-guided tissue acquisition, the FNB needle was more efficient and thus shortened the learning curve of EUSguided tissue acquisition in trainee endosonographers.

Citations

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  • Identification of Endosonographic Features that Compromise EUS-FNB Diagnostic Accuracy in Pancreatic Masses
    Hsueh-Chien Chiang, Chien-Jui Huang, Yao-Shen Wang, Chun-Te Lee, Meng-Ying Lin, Wei-Lun Chang
    Digestive Diseases and Sciences.2024; 69(11): 4302.     CrossRef
  • Tissue Quality Comparison Between Heparinized Wet Suction and Dry Suction in Endoscopic Ultrasound-Fine Needle Biopsy of Solid Pancreatic Masses: A Randomized Crossover Study
    Meng-Ying Lin, Cheng-Lin Wu, Yung-Yeh Su, Chien-Jui Huang, Wei-Lun Chang, Bor-Shyang Sheu
    Gut and Liver.2023; 17(2): 318.     CrossRef
  • Factors Affecting the Learning Curve in the Endoscopic Ultrasound-Guided Sampling of Solid Pancreatic Lesions: A Prospective Study
    Marcel Razpotnik, Simona Bota, Mathilde Kutilek, Gerolf Essler, Christian Urak, Julian Prosenz, Jutta Weber-Eibel, Andreas Maieron, Markus Peck-Radosavljevic
    Gut and Liver.2023; 17(2): 308.     CrossRef
  • Investigation into the content of red material in EUS-guided pancreatic cancer biopsies
    Meng-Ying Lin, Yung-Yeh Su, Yu-Ting Yu, Chien-Jui Huang, Bor-Shyang Sheu, Wei-Lun Chang
    Gastrointestinal Endoscopy.2023; 97(6): 1083.     CrossRef
  • 4,324 View
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Case Reports
Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma
Yujin Lee, Jaekwang Lee, Hyunsoo Kim, Changkeun Park, Jaekwon Jung, Daejin Kim, Yun Jin Chung, Hanjun Ryu
Clin Endosc 2022;55(2):287-291.   Published online April 1, 2021
DOI: https://doi.org/10.5946/ce.2020.272
AbstractAbstract PDFPubReaderePub
Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis.

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  • HEPATOPATHY SECONDARY TO INFILTRATION BY MALIGNANT MELANOMA: DIAGNOSTIC VALUE OF LIVER BIOPSY
    Alejandro García Martínez, Álvaro Morales Prado, Jorge Martínez-Echevarría Gil-Delgado, Daniel Mateos Millán
    Revista Española de Enfermedades Digestivas.2024;[Epub]     CrossRef
  • Metastatic melanoma: an unexpected cause of acute liver failure
    Robert S. O’Neill, Phillip Leaver, Connor Ryan, Sharron Liang, Santosh Sanagapalli, Rasha Cosman
    Clinical Journal of Gastroenterology.2024; 17(6): 1125.     CrossRef
  • Tumor lysis syndrome with hepatic failure- A rare presentation of undiagnosed metastatic melanoma
    Nicholas Cochran-Caggiano, Brandon Zaffuto, Ryan Dean
    JEM Reports.2023; 2(1): 100009.     CrossRef
  • Acute liver failure secondary to malignant infiltration: A single center experience
    Rocío González Grande, Ana Bravo Aranda, Inmaculada Santaella Leiva, Susana López Ortega, Miguel Jiménez Pérez
    Seminars in Oncology.2023; 50(3-5): 71.     CrossRef
  • 5,401 View
  • 159 Download
  • 3 Web of Science
  • 4 Crossref
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Micro-Biopsy Forceps in the Assessment of Peritoneal Carcinomatosis: A Possible New Indication?
Cecilia Binda, Emanuele Dabizzi, Emanuele Sinagra, Adele Fornelli, Luca Saragoni, Vincenzo Cennamo, Andrea Anderloni, Carlo Fabbri
Clin Endosc 2021;54(4):613-617.   Published online March 25, 2021
DOI: https://doi.org/10.5946/ce.2020.241
AbstractAbstract PDFPubReaderePub
Peritoneal carcinomatosis (PC) is defined as a metastatic involvement of the peritoneum by several other primary sites and it is characterized by a marked worsening of prognosis, with limited treatment opportunities. Subsequently, PC should be ruled out before any invasive treatment is administered. A new through-the-needle micro-biopsy forceps (MF) was recently introduced that permits micro-histology cores. In this case series, we evaluated the feasibility of MF in the assessment of PC to complete patient diagnostic work-ups. Five consecutive patients referred for endoscopic ultrasound staging were sampled using MF. Sampling was feasible in all patients with a technical success of 100%. No adverse events were reported in any cases. This technique was feasible and safe with a technical success rate of 100%. It permitted sampling of peritoneal irregularity, obtained high-quality tissue fragments in all cases, and enabled an additional assessment, i.e., immunohistochemical staining.

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  • Current perspectives on the diversification of endoscopic ultrasound-guided fine-needle aspiration and biopsy
    Shinpei Doi, Takako Adachi, Ayako Watanabe, Nobuhiro Katsukura, Takayuki Tsujikawa
    Journal of Medical Ultrasonics.2024; 51(2): 235.     CrossRef
  • Endoscopic ultrasound guided fine needle biopsy (EUS-FNB) from peritoneal lesions: a prospective cohort pilot study
    Pradermchai Kongkam, Theerapat Orprayoon, Sirilak Yooprasert, Nakarin Sirisub, Naruemon Klaikaew, Anapat Sanpawat, Shahram Safa, Wiriyaporn Ridtitid, Pinit Kullavanijaya, Rungsun Rerknimitr
    BMC Gastroenterology.2021;[Epub]     CrossRef
  • 4,285 View
  • 74 Download
  • 2 Web of Science
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Original Articles
High Sensitivity of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Lymphadenopathy Caused by Metastatic Disease: A Prospective Comparative Study
Per Hedenström, Vasilis Chatzikyriakos, Roozbeh Shams, Catarina Lewerin, Riadh Sadik
Clin Endosc 2021;54(5):722-729.   Published online March 4, 2021
DOI: https://doi.org/10.5946/ce.2020.283
AbstractAbstract PDFPubReaderePub
Background
/Aims: The diagnostic work-up of lymphadenopathy is challenging but important to determine the correct therapy. Nevertheless, few studies have addressed the topic of endosonography (EUS)-guided tissue acquisition in lymphadenopathy. Therefore, we aimed to evaluate the accuracy and safety of EUS-guided fine-needle biopsy sampling (EUS-FNB) in intrathoracic and intraabdominal lymphadenopathy.
Methods
In a tertiary care center, patients with lymphadenopathy referred for EUS-guided sampling were included prospectively from 2014 to 2019 (NCT02360839). In all cases, EUS-FNB (22 gauge) and EUS-guided fine-needle aspiration (EUS-FNA) (25 gauge) were performed. The patients were randomized to the first needle pass with FNB or FNA. Study outcomes were the diagnostic accuracy and adverse event rate.
Results
Forty-eight patients were included (median age: 69 years [interquartile range, 59–76]; 24/48 females [50%]). The final diagnoses were metastasis (n=17), lymphoma (n=11), sarcoidosis (n=6), and inflammatory disease (n=14). The diagnostic performance of the two modalities was comparable, including a high sensitivity for metastatic nodes (EUS-FNB: 87% vs. EUSFNA: 100%, p=0.5). The sensitivity for lymphoma was borderline superior in favor of EUS-FNB (EUS-FNB: 55% vs. EUS-FNA: 9%, p=0.06). No adverse events were recorded.
Conclusions
In lymphadenopathy, both EUS-FNB and EUS-FNA are safe and highly sensitive for metastatic lymph node detection. Lymphoma diagnosis is challenging regardless of the needle used.

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  • Lymphadenopathy Tissue Sampling by EUS-Guided Fine-Needle Biopsy Contributes to Meeting the Conditions for Genomic Profiling
    Mitsuru Sugimoto, Tadayuki Takagi, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Yuki Sato, Hiroki Irie, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira
    Journal of Clinical Gastroenterology.2025; 59(4): 369.     CrossRef
  • Clinical Utility of Endoscopic Ultrasound (EUS) and Endobronchial Ultrasound (EBUS) in the Evaluation of Mediastinal Lymphadenopathy
    Dominique Béchade
    Diagnostics.2025; 15(3): 349.     CrossRef
  • Endoscopic ultrasound-guided tissue sampling: European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review
    Antonio Facciorusso, Marianna Arvanitakis, Stefano Francesco Crinò, Carlo Fabbri, Adele Fornelli, John Leeds, Livia Archibugi, Silvia Carrara, Jahnvi Dhar, Paraskevas Gkolfakis, Beate Haugk, Julio Iglesias Garcia, Bertrand Napoleon, Ioannis S. Papanikolao
    Endoscopy.2025; 57(04): 390.     CrossRef
  • Transesophageal Bronchoscopic Ultrasound-guided Cryobiopsy (EUS-B-Cryo) for mediastinal lesions in critical airway obstruction: a case series with a systematic review
    Sanchit Mohan, A. J. Mahendran, Rohit Kumar, Manu Madan, Pranav Ish, Rajnish Kaushik, Nitesh Gupta
    Chest Disease Reports.2024;[Epub]     CrossRef
  • Comparison of 19-gauge conventional and Franseen needles for the diagnosis of lymphadenopathy and classification of malignant lymphoma using endoscopic ultrasound fine-needle aspiration
    Mitsuru Okuno, Keisuke Iwata, Tsuyoshi Mukai, Yusuke Kito, Takuji Tanaka, Naoki Watanabe, Senji Kasahara, Yuhei Iwasa, Akihiko Sugiyama, Youichi Nishigaki, Yuhei Shibata, Junichi Kitagawa, Takuji Iwashita, Eiichi Tomita, Masahito Shimizu
    Clinical Endoscopy.2024; 57(3): 364.     CrossRef
  • Diagnostic accuracy and safety of EUS-guided end-cutting fine-needle biopsy needles for tissue sampling of abdominal and mediastinal lymphadenopathies: a prospective multicenter series
    Silvia Carrara, Daoud Rahal, Kareem Khalaf, Tommy Rizkala, Glenn Koleth, Cristiana Bonifacio, Marta Andreozzi, Benedetto Mangiavillano, Francesco Auriemma, Paola Bossi, Monica Balzarotti, Antonio Facciorusso, Teresa Staiano, Elena Maldi, Marco Spadaccini,
    Gastrointestinal Endoscopy.2023; 98(2): 191.     CrossRef
  • Endoscopic Ultrasound-Guided Fine Needle Biopsy in the Diagnostic Work-Up of Deep-Seated Lymphadenopathies and Spleen Lesions: A Monocentric Experience
    Flaminia Bellisario, Fabia Attili, Fabrizia Campana, Federica Borrelli de Andreis, Silvia Bellesi, Elena Maiolo, Eleonora Alma, Rosalia Malafronte, Giuseppe Macis, Luigi Maria Larocca, Salvatore Annunziata, Francesco D’Alò, Stefan Hohaus
    Diagnostics.2023; 13(17): 2839.     CrossRef
  • Endoscopic ultrasound fine-needle biopsy vs fine-needle aspiration for lymph nodes tissue acquisition: a systematic review and meta-analysis
    Antonio Facciorusso, Stefano Francesco Crinò, Paraskevas Gkolfakis, Daryl Ramai, Andrea Lisotti, Ioannis S Papanikolaou, Benedetto Mangiavillano, Ilaria Tarantino, Andrea Anderloni, Carlo Fabbri, Konstantinos Triantafyllou, Pietro Fusaroli
    Gastroenterology Report.2022;[Epub]     CrossRef
  • A Novel Approach to Classification and Reporting of Lymph Node Fine-Needle Cytology: Application of the Proposed Sydney System
    Elena Vigliar, Gennaro Acanfora, Antonino Iaccarino, Massimo Mascolo, Daniela Russo, Giulia Scalia, Roberta Della Pepa, Claudio Bellevicine, Marco Picardi, Giancarlo Troncone
    Diagnostics.2021; 11(8): 1314.     CrossRef
  • Endoscopic Ultrasound Fine-Needle Biopsy versus Fine-Needle Aspiration for Tissue Sampling of Abdominal Lymph Nodes: A Propensity Score Matched Multicenter Comparative Study
    Antonio Facciorusso, Stefano Francesco Crinò, Nicola Muscatiello, Paraskevas Gkolfakis, Jayanta Samanta, Juliana Londoño Castillo, Christian Cotsoglou, Daryl Ramai
    Cancers.2021; 13(17): 4298.     CrossRef
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Comparison of Endoscopic Ultrasound-Guided Tissue Acquisition Using a 20-Gauge Menghini Needle with a Lateral Forward Bevel and a 22-Gauge Franseen Needle: A Single-Center Large Cohort Study
Takafumi Mie, Takashi Sasaki, Ryo Kanata, Takaaki Furukawa, Tsuyoshi Takeda, Akiyoshi Kasuga, Masato Matsuyama, Masato Ozaka, Naoki Sasahira
Clin Endosc 2021;54(5):730-738.   Published online March 4, 2021
DOI: https://doi.org/10.5946/ce.2020.251
AbstractAbstract PDFPubReaderePub
Background
/Aims: Several fine-needle biopsy (FNB) needles are available for endoscopic ultrasound (EUS)-guided tissue acquisition. However, there is disagreement on which type of needle has the best diagnostic yield. The aim of this study was to compare the performance and safety of two commonly used EUS-FNB needles.
Methods
We retrospectively analyzed consecutive patients who underwent EUS-FNB between June 2016 and March 2020 in our hospital. Two types of needles were evaluated: a 20-gauge Menghini needle with a lateral forward bevel and a 22-gauge Franseen needle. Rapid on-site evaluation was performed in all the cases. A multivariate analysis was performed to clarify the negative predictive factors for obtaining a histological diagnosis. Propensity score matching was performed to compare the diagnostic yields of these two needles.
Results
We analyzed 666 patients and 690 lesions. The overall diagnostic rate of histology alone was 88.8%, and the overall adverse event rate was 1.5%. Transduodenal access and small lesions (≤2 cm) were identified as negative predictive factors for obtaining a histological diagnosis. After propensity score matching, 482 lesions were analyzed. The diagnostic accuracy rates of histology in the M and F needle groups were 89.2% and 88.8%, respectively (p=1.00).
Conclusions
Both the needles showed high diagnostic yield, and no significant difference in performance was observed between the two.

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  • Adverse events of 20–22G second‐generation endoscopic ultrasound‐guided fine‐needle biopsy needles for solid lesions in the upper gastrointestinal tract and adjacent organs: Systematic review and meta‐analysis
    Cheng‐ye Pan, Shi‐min Wang, Dong‐hao Cai, Jia‐yi Ma, Shi‐yu Li, Yibin Guo, Sun Jing, Jin Zhendong, Kaixuan Wang
    Digestive Endoscopy.2025; 37(5): 490.     CrossRef
  • Primary Pancreatic Lymphoma: Endosonography-Guided Tissue Acquisition Diagnosis
    Anna Carolina Orsini-Arman , Rodrigo Cañada T Surjan, Filadélfio E Venco, José C Ardengh
    Cureus.2023;[Epub]     CrossRef
  • Diagnostic Yield of Serial Pancreatic Juice Aspiration Cytologic Examination With Brush Cytology for Pancreatic Ductal Stenosis
    Takafumi Mie, Takashi Sasaki, Tsuyoshi Takeda, Takeshi Okamoto, Chinatsu Mori, Takaaki Furukawa, Yuto Yamada, Akiyoshi Kasuga, Masato Matsuyama, Masato Ozaka, Naoki Sasahira
    Pancreas.2022; 51(8): 995.     CrossRef
  • Pancreatic follicular lymphoma: a report of two cases and literature review
    Takeshi Okamoto, Takashi Sasaki, Noriko Nishimura, Manabu Takamatsu, Chinatsu Mori, Takafumi Mie, Takaaki Furukawa, Yuto Yamada, Tsuyoshi Takeda, Akiyoshi Kasuga, Masato Matsuyama, Masato Ozaka, Dai Maruyama, Naoki Sasahira
    Clinical Journal of Gastroenterology.2021; 14(6): 1756.     CrossRef
  • 5,359 View
  • 105 Download
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Case Report
Endoscopic Ultrasound Through-the-Needle Biopsy for the Diagnosis of an Abdominal Bronchogenic Cyst
Jessica Cassiani, Stefano Francesco Crinò, Erminia Manfrin, Matteo Rivelli, Armando Gabbrielli, Alfredo Guglielmi, Corrado Pedrazzani
Clin Endosc 2021;54(5):767-770.   Published online February 17, 2021
DOI: https://doi.org/10.5946/ce.2020.195
AbstractAbstract PDFPubReaderePub
A 57-year-old woman with epigastric pain was diagnosed with a 6-cm abdominal cystic lesion of unclear origin on cross-sectional imaging. Endoscopic ultrasound (EUS) demonstrated a unilocular cyst located between the pancreas, gastric wall, and left adrenal gland, with a regular wall filled with dense fluid with multiple hyperechoic floating spots. A 19-G needle was used to puncture the cyst, but no fluid could be aspirated. Therefore, EUS-guided through-the-needle biopsy (EUS-TTNB) was performed. Histological analysis of the retrieved fragments revealed a fibrous wall lined by “respiratory-type” epithelium with ciliated columnar cells, consistent with the diagnosis of a bronchogenic cyst. Laparoscopic excision was performed, and the diagnosis was confirmed based on the findings of the surgical specimen. Abdominal bronchogenic cysts are extremely uncommon, and a definitive diagnosis is commonly obtained after the examination of surgical specimens due to the lack of pathognomonic findings on cross-sectional imaging and poor cellularity on EUS-guided fine-needle aspiration cytology. EUS-TTNB is useful for establishing a preoperative histological diagnosis, thus supporting the decision-making process.

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  • Optimal resection of gastric bronchogenic cysts based on anatomical continuity with adherent gastric muscular layer: A case report
    Masayoshi Terayama, Koshi Kumagai, Hiroshi Kawachi, Rie Makuuchi, Masaru Hayami, Satoshi Ida, Manabu Ohashi, Takeshi Sano, Souya Nunobe
    World Journal of Gastrointestinal Surgery.2023; 15(6): 1216.     CrossRef
  • Retroperitoneal tumor finally diagnosed as a bronchogenic cyst: A case report and review of literature
    Yang-Yang Gong, Xin Qian, Bo Liang, Ming-Dong Jiang, Jun Liu, Xing Tao, Jing Luo, Hong-Jian Liu, You-Gang Feng
    World Journal of Clinical Cases.2022; 10(19): 6679.     CrossRef
  • Endoscopic resection in the treatment of intramural esophageal bronchogenic cysts: A retrospective analysis of 17 cases
    Jiao Jiao, Xiaofei Fan, Lili Luo, Zhongqing Zheng, Bangmao Wang, Wentian Liu
    Digestive and Liver Disease.2022; 54(12): 1691.     CrossRef
  • Subdiaphragmatic bronchogenic cysts: Case series and literature review
    Jianchun Xiao, Xueyang Zhang, Hongru Zhou, Tao Hong, Binglu Li, Xiaodong He, Wei Liu
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • 4,878 View
  • 69 Download
  • 5 Web of Science
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Original Articles
Superior Specimen and Diagnostic Accuracy with Endoscopic Ultrasound-Guided Liver Biopsies Using 19-Gauge versus 22-Gauge Core Needles
Rucha M. Shah, Jason Schmidt, Elizabeth John, Sheila Rastegari, Priyanka Acharya, Prashant Kedia
Clin Endosc 2021;54(5):739-744.   Published online November 13, 2020
DOI: https://doi.org/10.5946/ce.2020.212
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided liver biopsy (EUS-LB) is an effective and safe method of procuring liver tissue. The aims of this study were to assess and compare the outcomes and tissue adequacy of a single-pass, single-actuation, wet suction technique between 19 G and 22 G needles in patients undergoing EUS-LB.
Methods
We performed a prospective case series study of 20 patients undergoing EUS-LB at a single center between September 2017 and April 2020. The primary objective was to evaluate differences in sample adequacy via a single actuation wet suction technique between a 19 G core needle and a 22 G core needle. Adequacy was gauged by cumulative core biopsy length and the number of portal tracts visualized.
Results
The 19 G needle provided a longer core length (2.5 cm vs. 1.2 cm, p<0.0001), more complete portal tracts (5.8 vs. 1.7, p<0.0001), more total tracts (8.8 vs. 3, p<0.0001), and a longer, intact, fragment length (0.75 cm vs. 0.32 cm, p<0.0006). The 19 G needle was superior in providing adequate (60% vs. 5%, p<0.001) and diagnostic pathologic samples (85% vs. 10%, p<0.001).
Conclusions
A single-pass, single-actuation, wet suction technique using a 19 G needle is superior to that using a 22 G needle for tissue acquisition and sample adequacy in EUS-LB.

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  • The Benign Liver EUS Optimal Core Study (BLOCs)
    Neil R. Sharma, Harishankar Gopakumar, Harshit Khara, Abhilash Perisetti, Saurabh Gupta, Mariajose Rojas DeLeon, Marzena Muller, Christina Zelt, Mindy Flanagan, Ashley Rumple, Amitpal Johal, Bradley Confer, Jiahong Li, Meir Mizrahi, Ann Chen, Kefu Li, Moh
    Journal of Clinical Gastroenterology.2025;[Epub]     CrossRef
  • Comparison of diagnostic outcomes, safety, and cost of Franseen-tip 19G versus 22G needles for endoscopic ultrasound-guided liver biopsies
    Ankit Dalal, Nagesh Kamat, Gaurav Patil, Amol Vadgaonkar, Sanil Parekh, Sehajad Vora, Amit Maydeo
    Endoscopy International Open.2024; 12(02): E291.     CrossRef
  • Endoscopic ultrasound-guided tissue acquisition for the diagnosis of focal liver lesion
    Alina Tantău, Cosmina Sutac, Anamaria Pop, Marcel Tantău
    World Journal of Radiology.2024; 16(4): 72.     CrossRef
  • Endo-hepatology: Why should we do endoscopic ultrasound-guided interventions to the liver that we could do through the skin?
    Claudio Calvanese, Pietro Fusaroli
    World Journal of Gastroenterology.2024; 30(40): 4333.     CrossRef
  • EUS-guided left lobe liver biopsy: Safer modality with similar diagnostic yield as right lobe: a pilot study
    Mithun Sharma, Sundeep Lakhtakia, Nitin Jagtap, Anuradha Sekaran, Rakesh Kalapala, Basha Jahangeer, Anand Kulkarni, Mohan Ramchandani, Rajesh Gupta, Swapna Samudraala, Juhi Khanna, Padaki Nagaraja, Sowmya Iyengar, Baker Ali Gora, Guduru Venkat Rao, Nagesh
    Endoscopy International Open.2023; 11(02): E172.     CrossRef
  • Endoscopic ultrasound-guided liver biopsy using a single-pass, slow-pull technique with a 19-G Franseen tip fine-needle biopsy needle: A prospective study
    Praveer Rai, Abdul Majeed, Pankaj Kumar, Mayank Rajput, Amit Goel, Ram Naval Rao
    Indian Journal of Gastroenterology.2023; 42(3): 418.     CrossRef
  • Quality of Tissue Samples Obtained by Endoscopic Ultrasound-Guided Liver Biopsy: A Randomized, Controlled Clinical Trial
    José Lariño-Noia, Javier Fernández-Castroagudín, Daniel de la Iglesia-García, Héctor Lázare, Laura Nieto, Sol Porto, Nicolau Vallejo-Senra, Esther Molina, Alba San Bruno, Xurxo Martínez-Seara, Julio Iglesias-García, Silvia García-Acuña, J. Enrique Domíngu
    American Journal of Gastroenterology.2023; 118(10): 1821.     CrossRef
  • Distinct ways to perform a liver biopsy: The core technique setups and updated understanding of these modalities
    Chao Sun, Xingliang Zhao, Lei Shi, Xiaofei Fan, Xiaolong Qi
    Endoscopic Ultrasound.2023; 12(6): 437.     CrossRef
  • Role of endoscopic ultrasound-guided liver biopsy: a meta-analysis
    Keyu Zeng, Zhenpeng Jiang, Jie Yang, Kefei Chen, Qiang Lu
    Scandinavian Journal of Gastroenterology.2022; 57(5): 545.     CrossRef
  • Update on endoscopic ultrasound-guided liver biopsy
    Shiva Rangwani, Devarshi R Ardeshna, Khalid Mumtaz, Sean G Kelly, Samuel Y Han, Somashekar G Krishna
    World Journal of Gastroenterology.2022; 28(28): 3586.     CrossRef
  • Diagnostic and interventional EUS in hepatology: An updated review
    Vaneet Jearth, Sridhar Sundaram, Surinder Singh Rana
    Endoscopic Ultrasound.2022; 11(5): 355.     CrossRef
  • 5,037 View
  • 95 Download
  • 14 Web of Science
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Close layer
Endoscopic Ultrasound-Guided, Percutaneous, and Transjugular Liver Biopsy: A Comparative Systematic Review and Meta-Analysis
Thomas R. McCarty, Ahmad Najdat Bazarbashi, Basile Njei, Marvin Ryou, Harry R. Aslanian, Thiruvengadam Muniraj
Clin Endosc 2020;53(5):583-593.   Published online September 29, 2020
DOI: https://doi.org/10.5946/ce.2019.211
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background
/Aims: Percutaneous liver biopsy (PCLB) or transjugular liver biopsy (TJLB) have traditionally been performed to obtain a sample of hepatic tissue; however, endoscopic ultrasound-guided liver biopsy (EUSLB) has become an attractive alternative. The aim of this study was to compare the efficacy and safety of EUSLB, PCLB, and TJLB.
Methods
Search strategies were developed in accordance with PRISMA and MOOSE guidelines. Major outcomes included the following: adequacy of biopsy specimens (i.e., complete portal triads [CPT], total specimen length [TSL] in mm, and length of longest piece [LLP]) in mm), and rate of adverse events. Only studies comparing all biopsy approaches (i.e., EUSLB, PCLB, and TJLB) were included.
Results
Five studies (EUSLB [n=301]; PCLB [n=176]; and TJLB [n=179]) were included. Biopsy cumulative adequacy rates for EUSLB, PCLB, and TJLB were 93.51%, 98.27%, and 97.61%, respectively. Based on the subgroup analysis limited to EUS biopsy needles in current clinical practice, there was no difference in biopsy adequacy or adverse events for EUSLB compared to PCLB and TJLB (all p>0.050). A comparison of EUSLB and PCLB revealed no difference between specimens regarding both CPT (p=0.079) and LLP (p=0.085); however, a longer TSL (p<0.001) was observed. Compared to TJLB, EUSLB showed no difference in LLP (p=0.351), fewer CPT (p=0.042), and longer TSL (p=0.005).
Conclusions
EUSLB appears to be a safe, minimally invasive procedure that is comparable to PCLB and TJLB regarding biopsy specimens obtained and rate of adverse events associated with each method.

Citations

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  • Endoscopic ultrasound-guided liver biopsy in liver transplant recipients: A preliminary experience
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    Hepatobiliary & Pancreatic Diseases International.2025; 24(1): 108.     CrossRef
  • Endohepatology: Bridging Gastroenterology and Hepatology through Advanced Endoscopic Interventions
    Nitin Jagtap, Sundeep Lakhtakia
    Current Hepatology Reports.2025;[Epub]     CrossRef
  • Endohepatology
    Nicole Ferrante, Kalyan Ram Bhamidimarri, Sunil Amin
    Clinics in Liver Disease.2025; 29(2): 253.     CrossRef
  • Endoscopic ultrasound guided liver biopsy and portal pressure gradient: when, why and how? Can it become the standard of care in endo-hepatology?
    Jahnvi Dhar, Amit Yadav, Suvradeep Mitra, Zaheer Nabi, Manik Aggarwal, Pankaj Gupta, Antonio Facciorusso, Stefano Francesco Crinò, Guru Trikudanathan, Jayanta Samanta
    Expert Review of Gastroenterology & Hepatology.2025; 19(3): 311.     CrossRef
  • Quality Indicators for EUS
    Girish Mishra, Anne Marie Lennon, Nonthalee Pausawasdi, Vanessa M. Shami, Reem Z. Sharaiha, B. Joseph Elmunzer
    American Journal of Gastroenterology.2025; 120(5): 973.     CrossRef
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    Diagnostics.2025; 15(8): 967.     CrossRef
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    Girish Mishra, Anne Marie Lennon, Nonthalee Pausawasdi, Vanessa M. Shami, Reem Z. Sharaiha, B. Joseph Elmunzer
    Gastrointestinal Endoscopy.2025; 101(5): 928.     CrossRef
  • Endo-Hepatologie: Neue endoskopische Lösungen für alte hepatologische Probleme
    Michael Praktiknjo, Matthias Dollinger, Barbara Braden, Wim Laleman, Jonel Trebicka
    Zeitschrift für Gastroenterologie.2025;[Epub]     CrossRef
  • Endoscopic ultrasound in hepatology: ushering a new era in liver disease management
    Andrada Seicean, Irina Dragomir, Bogdan Procopet
    Current Opinion in Gastroenterology.2025;[Epub]     CrossRef
  • Surface area outcomes in EUS-guided liver biopsy: a comparative study of Franseen and Fork-tip needles
    Kotaro Matsumoto, Shinpei Doi, Takako Adachi, Ayako Watanabe, Nobuhiro Katsukura, Takayuki Tsujikawa, Tatsuya Aso, Mikiko Takahashi, Kentaro Kikuchi
    BMC Gastroenterology.2025;[Epub]     CrossRef
  • Liver biopsy and acute hepatology in intensive care unit patients
    Lukas Mätzold, Florian Roßner, Frank Tacke
    Expert Review of Gastroenterology & Hepatology.2025; : 1.     CrossRef
  • Endoscopic procedures in hepatology: Current trends and new developments
    Wim Laleman, Emma Vanderschueren, Zain Seyad Mehdi, Reiner Wiest, Andres Cardenas, Jonel Trebicka
    Journal of Hepatology.2024; 80(1): 124.     CrossRef
  • Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases
    Susana G. Rodrigues, Schalk van der Merwe, Aleksander Krag, Reiner Wiest
    Seminars in Immunology.2024; 71: 101859.     CrossRef
  • Comparison of diagnostic outcomes, safety, and cost of Franseen-tip 19G versus 22G needles for endoscopic ultrasound-guided liver biopsies
    Ankit Dalal, Nagesh Kamat, Gaurav Patil, Amol Vadgaonkar, Sanil Parekh, Sehajad Vora, Amit Maydeo
    Endoscopy International Open.2024; 12(02): E291.     CrossRef
  • Comparison of Diagnostic Accuracy and Diagnostic Adequacy Between Endoscopic Ultrasound-Guided and Percutaneous Liver Biopsies: A Meta-Analysis of Randomized Controlled Trials and Observational Studies
    Mansoor Ahmad, Taslova Tahsin Abedin, Faria Khilji, Kinan Obeidat, Lam Vinh Sieu, Sandipkumar S Chaudhari, Divine Besong Arrey Agbor, Danish Allahwala
    Cureus.2024;[Epub]     CrossRef
  • How to incorporate endohepatology into your bariatric practice
    Pichamol Jirapinyo
    iGIE.2024; 3(2): 293.     CrossRef
  • Ultrasound-guided percutaneous liver biopsy: A review of what operators need to know
    Husain Alturkistani, Abdullah H. Alsergani, Meshari Alzeer, Anas Alturkistani, Renad Zaini, Salem Bauones
    Medicine.2024; 103(30): e38673.     CrossRef
  • Diagnostic Endoscopic Ultrasound
    Mark J. Radlinski, Himesh B. Zaver, Vanessa M. Shami
    Gastroenterology Clinics of North America.2024; 53(4): 663.     CrossRef
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    Therapeutic Advances in Gastroenterology.2024;[Epub]     CrossRef
  • Progress in the Study of Surgical Methods of Liver Biopsy
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    Advances in Clinical Medicine.2024; 14(12): 1192.     CrossRef
  • Comparative accuracy of endosonographic shear wave elastography and transcutaneous liver stiffness measurement: a pilot study
    Divyanshoo R. Kohli, Daniel Mettman, Nevene Andraws, Erin Haer, Jaime Porter, Ozlem Ulusurac, Steven Ullery, Madhav Desai, Mohammad S. Siddiqui, Prateek Sharma
    Gastrointestinal Endoscopy.2023; 97(1): 35.     CrossRef
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    Saurabh Chandan, Smit Deliwala, Shahab R. Khan, Babu P. Mohan, Banreet S. Dhindsa, Jay Bapaye, Hemant Goyal, Lena L. Kassab, Faisal Kamal, Harlan R. Sayles, Gursimran S. Kochhar, Douglas G. Adler
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    Seminars in Liver Disease.2023; 43(02): 176.     CrossRef
  • Quality of Tissue Samples Obtained by Endoscopic Ultrasound-Guided Liver Biopsy: A Randomized, Controlled Clinical Trial
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    American Journal of Gastroenterology.2023; 118(10): 1821.     CrossRef
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    Clinical Liver Disease.2023; 22(2): 42.     CrossRef
  • Technical Success, Sample Adequacy, and Complications of  Pediatric Transjugular Liver Biopsy: A Systematic Review and Meta-Analysis
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    Digestive Diseases and Sciences.2023; 68(10): 3846.     CrossRef
  • Role of endoscopic ultrasound and endoscopic ultrasound-guided tissue acquisition in diagnosing hepatic focal lesions
    Hussein Hassan Okasha, Hanane Delsa, Abdelmoneim Alsawaf, Ahmed Morad Hashim, Hani M Khattab, Dalia Abdelfatah, Abeer Abdellatef, Amr Albitar
    World Journal of Methodology.2023; 13(4): 287.     CrossRef
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    Journal of Pancreatology.2023; 6(4): 139.     CrossRef
  • Distinct ways to perform a liver biopsy: The core technique setups and updated understanding of these modalities
    Chao Sun, Xingliang Zhao, Lei Shi, Xiaofei Fan, Xiaolong Qi
    Endoscopic Ultrasound.2023; 12(6): 437.     CrossRef
  • Endo-Hepatology: The Buzz Goes Much beyond Liver Biopsy—A Narrative Review
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    Journal of Digestive Endoscopy.2023; 14(04): 227.     CrossRef
  • Diagnostic yield of endoscopic ultrasound-guided liver biopsy in comparison to percutaneous liver biopsy: a systematic review and meta-analysis
    Antonio Facciorusso, Stefano Francesco Crinò, Daryl Ramai, Carlo Fabbri, Benedetto Mangiavillano, Andrea Lisotti, Nicola Muscatiello, Christian Cotsoglou, Pietro Fusaroli
    Expert Review of Gastroenterology & Hepatology.2022; 16(1): 51.     CrossRef
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    Techniques and Innovations in Gastrointestinal Endoscopy.2022; 24(2): 127.     CrossRef
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Endoscopic Ultrasound-Guided Fine Needle Biopsy Needles Provide Higher Diagnostic Yield Compared to Endoscopic Ultrasound-Guided Fine Needle Aspiration Needles When Sampling Solid Pancreatic Lesions: A Meta-Analysis
Benjamin D. Renelus, Daniel S. Jamorabo, Iman Boston, William M. Briggs, John M. Poneros
Clin Endosc 2021;54(2):261-268.   Published online August 31, 2020
DOI: https://doi.org/10.5946/ce.2020.101
AbstractAbstract PDFPubReaderePub
Background
/Aims: Studies comparing the utility of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for solid pancreatic lesions have been inconclusive with no clear superiority. The aim of this meta-analysis was to compare the diagnostic accuracy and safety between the two sampling techniques.
Methods
We performed a systematic search of randomized controlled trials published between 2012 and 2019. The primary outcome was overall diagnostic accuracy. Secondary outcomes included adverse event rates, cytopathologic and histopathologic accuracy, and the mean number of passes required to obtain adequate tissue between FNA and FNB needles. Fixed and random effect models with pooled estimates of target outcomes were developed.
Results
Eleven studies involving 1,365 participants were included for analysis. When compared to FNB, FNA had a significant reduction in diagnostic accuracy (81% and 87%, p=0.005). In addition, FNA provided reduced cytopathologic accuracy (82% and 89%, p=0.04) and an increased number of mean passes required compared to FNB (2.3 and 1.6, respectively, p<0.0001). There was no difference in adverse event rate between FNA and FNB needles (1.8% and 2.3% respectively, p=0.64).
Conclusions
FNB provides superior diagnostic accuracy without compromising safety when compared to FNA. FNB should be readily considered by endosonographers when evaluating solid pancreatic masses.

Citations

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  • Randomized trial comparing the Franseen needle versus 2 types of sharpened-tip 3-prong needles in EUS-guided tissue acquisition from solid pancreatic lesions
    Takuya Ishikawa, Hirotaka Suzuki, Yasuki Hori, Jun Yashika, Hiroki Suhara, Hajime Sumi, Masahiko Ando, Yachiyo Kuwatsuka, Kentaro Yamao, Yasuyuki Mizutani, Tadashi Iida, Kota Uetsuki, Takeshi Yamamura, Kazuhiro Furukawa, Masanao Nakamura, Hiromi Kataoka,
    Gastrointestinal Endoscopy.2025;[Epub]     CrossRef
  • The yield of cytology and histology obtained by endoscopic ultrasound‐guided fine needle aspiration and biopsy needles in the diagnosis of pancreatic adenocarcinoma
    Wisam Sbeit, Nidaa Abu Hanna, Livoff Alejandro, Tawfik Khoury
    Cytopathology.2024; 35(1): 92.     CrossRef
  • Diagnosis of lung squamous cell carcinoma using EUS-guided fine-needle biopsy sampling of a lung lesion
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    iGIE.2024; 3(1): 32.     CrossRef
  • EUS-guided tissue acquisition in patients with solid pseudopapillary neoplasms of the pancreas
    José M. Jiménez-Gutiérrez, José G. de la Mora-Levy, Juan O. Alonso-Lárraga, Angélica I. Hernández-Guerrero, Betsabé A. Soriano-Herrera, Lidia F. Villegas-González, Luis F. Uscanga-Domínguez, Stephanie López-Romero, Félix I. Téllez-Ávila
    Postgraduate Medicine.2024; 136(1): 78.     CrossRef
  • Endoscopic Ultrasound-Guided Fine-Needle Biopsy Versus Aspiration for Tissue Sampling Adequacy for Molecular Testing in Pancreatic Ductal Adenocarcinoma
    Wael T. Mohamed, Vinay Jahagirdar, Fouad Jaber, Mohamed K. Ahmed, Ifrah Fatima, Thomas Bierman, Zhuxuan Fu, Philip G. Jones, Amira F. Hassan, Erin Faber, Wendell K. Clarkston, Hassan Ghoz, Ossama W. Tawfik, Sreeni Jonnalagadda
    Cancers.2024; 16(4): 761.     CrossRef
  • Endoscopic ultrasound‐guided biopsy using a three‐prong asymmetry tip needle for pancreatic tumors and peridigestive tract lesions: Retrospective single‐center study
    Kento Shionoya, Ryosuke Tonozuka, Shuntaro Mukai, Takayoshi Tsuchiya, Reina Tanaka, Kenjiro Yamamoto, Kazumasa Nagai, Yukitoshi Mastunami, Hiroyuki Kojima, Takao Itoi
    Journal of Hepato-Biliary-Pancreatic Sciences.2024; 31(4): 294.     CrossRef
  • The factors that influence the diagnostic accuracy and sample adequacy of EUS-guided tissue acquisition for the diagnosis of solid pancreatic lesions
    Liqi Sun, Yuqiong Li, Qiuyue Song, Lisi Peng, Ying Xing, Haojie Huang, Zhendong Jin
    Endoscopic Ultrasound.2024; 13(3): 183.     CrossRef
  • Experience of Endoscopic Ultrasound Guided Fine Needle Aspiration and Fine Needle Biopsy: Data from Tertiary Care Hospital in Pakistan
    Hafiz Irfan Mushtaq, Fariha Shams, Shafqat Rasool, Ghias Ul Hassan, Sadia Jabbar, Farwa Javed, Sidra Rasheed, Akif Dlishad, Ghias Un Nabi Tayyab
    Pakistan Journal of Health Sciences.2024; : 31.     CrossRef
  • Impact of macroscopic on-site evaluation (MOSE) on accuracy of endoscopic ultrasound-guided fine-needle aspiration/biopsy of solid lesions
    Hussein Okasha, Ahmed Ebrahim, Ihab Samih, Mohammed Sayed
    International Journal of Gastrointestinal Intervention.2024; 13(3): 98.     CrossRef
  • The Role of CT-guided Core Needle Biopsy in Pancreatic Tumors: An Initial Evaluation in Modern Oncology
    Eduardo P. Eyheremendy, Cristian A. Angeramo, Patricio Méndez
    Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2024; 34(6): 578.     CrossRef
  • Endoscopic Tissue Sampling of Solid Pancreatic Lesions for Molecular Analysis
    Divya M. Chalikonda, Uzma D. Siddiqui
    Techniques and Innovations in Gastrointestinal Endoscopy.2024; 26(4): 347.     CrossRef
  • Minimally Invasive Sampling of Mediastinal Lesions
    Alberto Fantin, Nadia Castaldo, Ernesto Crisafulli, Giulia Sartori, Alice Villa, Elide Felici, Stefano Kette, Filippo Patrucco, Erik H. F. M. van der Heijden, Paolo Vailati, Giuseppe Morana, Vincenzo Patruno
    Life.2024; 14(10): 1291.     CrossRef
  • EUS-FNA techniques in the pathological diagnosis of pancreatic disease
    Atsushi KANNO, Akitsugu TANAKA, Yusuke SAKURAI, Eriko IKEDA, Kozue ANDO, Kensuke YOKOYAMA, Hironori YAMAMOTO
    Suizo.2024; 39(5): 305.     CrossRef
  • Endoscopic Ultrasound-Guided Pancreatic Tissue Sampling: Lesion Assessment, Needles, and Techniques
    Jahnvi Dhar, Jayanta Samanta, Zaheer Nabi, Manik Aggarwal, Maria Cristina Conti Bellocchi, Antonio Facciorusso, Luca Frulloni, Stefano Francesco Crinò
    Medicina.2024; 60(12): 2021.     CrossRef
  • ACG Clinical Guideline: Diagnosis and Management of Biliary Strictures
    B. Joseph Elmunzer, Jennifer L. Maranki, Victoria Gómez, Anna Tavakkoli, Bryan G. Sauer, Berkeley N. Limketkai, Emily A. Brennan, Elaine M. Attridge, Tara J. Brigham, Andrew Y. Wang
    American Journal of Gastroenterology.2023; 118(3): 405.     CrossRef
  • Comprehensive review on endoscopic ultrasound-guided tissue acquisition techniques for solid pancreatic tumor
    Sakue Masuda, Kazuya Koizumi, Kento Shionoya, Ryuhei Jinushi, Makomo Makazu, Takashi Nishino, Karen Kimura, Chihiro Sumida, Jun Kubota, Chikamasa Ichita, Akiko Sasaki, Masahiro Kobayashi, Makoto Kako, Uojima Haruki
    World Journal of Gastroenterology.2023; 29(12): 1863.     CrossRef
  • Pancreatic duct lavage cytology combined with a cell-block method for patients with possible pancreatic ductal adenocarcinomas, including pancreatic carcinoma in situ
    Hiroaki Kusunose, Shinsuke Koshita, Yoshihide Kanno, Takahisa Ogawa, Toshitaka Sakai, Keisuke Yonamine, Kazuaki Miyamoto, Fumisato Kozakai, Hideyuki Anan, Kazuki Endo, Haruka Okano, Masaya Oikawa, Takashi Tsuchiya, Takashi Sawai, Yutaka Noda, Kei Ito
    Clinical Endoscopy.2023; 56(3): 353.     CrossRef
  • Current status and issues in genomic analysis using EUS-FNA/FNB specimens in hepatobiliary–pancreatic cancers
    Yoshinori Ozono, Hiroshi Kawakami, Naomi Uchiyama, Hiroshi Hatada, Souichiro Ogawa
    Journal of Gastroenterology.2023; 58(11): 1081.     CrossRef
  • Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma
    Abhirup Chatterjee, Jimil Shah
    Diagnostics.2023; 14(1): 78.     CrossRef
  • Diagnostic value of endoscopic ultrasound in groove pancreatitis
    Yu Mo She, Nan Ge
    Annals of Medicine.2023;[Epub]     CrossRef
  • The Role of Endoscopic Ultrasonography in the Diagnosis and Staging of Pancreatic Cancer
    Ali Zakaria, Bayan Al-Share, Jason B. Klapman, Aamir Dam
    Cancers.2022; 14(6): 1373.     CrossRef
  • A Meta-Analysis Comparing Endoscopic Ultrasound-guided Fine-needle Aspiration With Endoscopic Ultrasound-guided Fine-needle Biopsy
    Zhiwang Li, Wei Liu, Xiaoda Xu, Peiyu Li
    Journal of Clinical Gastroenterology.2022; 56(8): 668.     CrossRef
  • Endoscopic ultrasound‐guided tissue acquisition for pancreatic ductal adenocarcinoma in the era of precision medicine
    Reiko Ashida, Masayuki Kitano
    Digestive Endoscopy.2022; 34(7): 1329.     CrossRef
  • Diagnostic performance of endoscopic ultrasound-guided tissue acquisition by EUS-FNA versus EUS-FNB for solid pancreatic mass without ROSE: a retrospective study
    Thanawin Wong, Tanawat Pattarapuntakul, Nisa Netinatsunton, Bancha Ovartlarnporn, Jaksin Sottisuporn, Naichaya Chamroonkul, Pimsiri Sripongpun, Sawangpong Jandee, Apichat Kaewdech, Siriboon Attasaranya, Teerha Piratvisuth
    World Journal of Surgical Oncology.2022;[Epub]     CrossRef
  • Endoscopic ultrasound-guided tissue acquisition: Needle types, technical issues, and sample handling
    Woo Hyun Paik
    International Journal of Gastrointestinal Intervention.2022; 11(3): 96.     CrossRef
  • Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis
    Yen-Chih Lin, Hsu-Heng Yen, Siou-Ping Huang, Kai-Lun Shih, Yang-Yuan Chen
    Diagnostics.2022; 12(9): 2123.     CrossRef
  • Endoscopic Ultrasound Guided Fine Needle Aspiration versus Endoscopic Ultrasound Guided Fine Needle Biopsy for Pancreatic Cancer Diagnosis: A Systematic Review and Meta-Analysis
    Galab M. Hassan, Louise Laporte, Sarto C. Paquin, Charles Menard, Anand V. Sahai, Benoît Mâsse, Helen Trottier
    Diagnostics.2022; 12(12): 2951.     CrossRef
  • Endoscopic Ultrasound Quality Metrics in Clinical Practice
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    Diagnostics.2021; 11(2): 242.     CrossRef
  • Personalized Approach to the Role of Endoscopic Ultrasound in the Diagnosis and Management of Pancreaticobiliary Malignancies
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    Journal of Personalized Medicine.2021; 11(3): 180.     CrossRef
  • Diagnostic Yield of Endoscopic Ultrasound-Guided Liver Biopsy in Comparison to Percutaneous Liver Biopsy: A Two-Center Experience
    Antonio Facciorusso, Daryl Ramai, Maria Cristina Conti Bellocchi, Laura Bernardoni, Erminia Manfrin, Nicola Muscatiello, Stefano Francesco Crinò
    Cancers.2021; 13(12): 3062.     CrossRef
  • Endoscopic ultrasound‐guided fine‐needle biopsy histology with a 22‐gauge Franseen needle and fine‐needle aspiration liquid‐based cytology with a conventional 25‐gauge needle provide comparable diagnostic accuracy in solid pancreatic lesions
    Yoichi Tomita, Yuichi Torisu, Masafumi Chiba, Yuji Kinoshita, Takafumi Akasu, Nana Shimamoto, Takahiro Abe, Keisuke Kanazawa, Kazuki Takakura, Shintaro Tsukinaga, Masanori Nakano, Hirobumi Toyoizumi, Masayuki Kato, Masayuki Saruta
    JGH Open.2021; 5(9): 1092.     CrossRef
  • Comparison of Endoscopic Ultrasound-Guided Tissue Acquisition Using a 20-Gauge Menghini Needle with a Lateral Forward Bevel and a 22-Gauge Franseen Needle: A Single-Center Large Cohort Study
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    Clinical Endoscopy.2021; 54(5): 730.     CrossRef
  • 6,481 View
  • 209 Download
  • 28 Web of Science
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Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors
Yoshiko Nakano, Toshitatsu Takao, Yoshinori Morita, Shinwa Tanaka, Takashi Toyonaga, Eiji Umegaki, Yuzo Kodama
Clin Endosc 2020;53(5):575-582.   Published online February 14, 2020
DOI: https://doi.org/10.5946/ce.2019.150
AbstractAbstract PDFPubReaderePub
Background
/Aims: Mucosal cutting biopsy (MCB) is useful for the histopathological diagnosis of gastric subepithelial tumors (SETs). However, there is little information on cases in which MCB did not establish a diagnosis. In the current study, we aimed to investigate the characteristics of cases in which MCB was unsuccessful.
Methods
Cases in which MCB was used to histopathologically diagnose gastric SETs at Kobe University Hospital between August 2012 and October 2018 were retrospectively reviewed.
Results
Forty-five cases in which MCB was used to diagnose 43 gastric SETs in 43 patients were analyzed. The median tumor size was 20 mm (range, 8–50 mm). Pathological examinations resulted in definitive and suspected diagnoses and no diagnosis in 29 (gastrointestinal stromal tumor: n=17, leiomyoma: n=7, aberrant pancreas: n=3, others: n=2), 6, and 10 cases, respectively. Failure to expose the tumor according to retrospective examinations of endoscopic images was significantly associated with no diagnosis. Other possible explanations included a less elevated tumor, biopsy of the surrounding field instead of the tumor due to the mobility, and poor endoscope maneuverability due to the tumor being close to the cardia.
Conclusions
Clear exposure of gastric SETs during MCB may improve the diagnostic rate of such examinations.

Citations

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  • Endoscopic ultrasound-guided bite-on-bite biopsy and endoscopic ultrasound-guided fine-needle aspiration in the diagnosis of gastric tumors with negative malignant endoscopy biopsies: a retrospective cohort study
    Liang Min, Yan Jin, Jiefei Chen, Hongyi Zhu, Chengbai Liang, Liang Lv, Yongjun Wang, Deliang Liu, Yuqian Zhou, Yi Chu, Yuyong Tan
    Minimally Invasive Therapy & Allied Technologies.2025; 34(2): 96.     CrossRef
  • Diagnostic ability and adverse events of mucosal incision‐assisted biopsy for gastric subepithelial tumors: Systematic review and meta‐analysis
    Eriko Koizumi, Osamu Goto, Akihisa Matsuda, Toshiaki Otsuka, Yumiko Ishikawa, Shun Nakagome, Masahiro Niikawa, Tsugumi Habu, Keiichiro Yoshikata, Kumiko Kirita, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Jun Omori, Naohiko Akimoto, Hiroshi Yoshida, Kat
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  • Technical outcomes and postprocedural courses of mucosal incision‐assisted biopsy for possible gastric gastrointestinal stromal tumors: A series of 48 cases (with video)
    Eriko Koizumi, Osamu Goto, Shun Nakagome, Tsugumi Habu, Yumiko Ishikawa, Kumiko Kirita, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Teppei Akimoto, Jun Omori, Naohiko Akimoto, Katsuhiko Iwakiri
    DEN Open.2024;[Epub]     CrossRef
  • Utility and advantage of the unroofing technique for gastrointestinal subepithelial tumors: A multicenter retrospective cohort study
    Masashi Yamamoto, Tsutomu Nishida, Ryotaro Uema, Takashi Kanesaka, Hiroyuki Ogawa, Shinji Kitamura, Hideki Iijima, Kengo Nagai, Shusaku Tsutsui, Masato Komori, Katsumi Yamamoto, Yoshiki Tsujii, Yoshito Hayashi, Tetsuo Takehara
    DEN Open.2024;[Epub]     CrossRef
  • Systematic Endoscopic Approach for Diagnosing Gastric Subepithelial Tumors
    Gwang Ha Kim
    Gut and Liver.2022; 16(1): 19.     CrossRef
  • The Diagnosis of Small Gastrointestinal Subepithelial Lesions by Endoscopic Ultrasound-Guided Fine Needle Aspiration and Biopsy
    Masanari Sekine, Takeharu Asano, Hirosato Mashima
    Diagnostics.2022; 12(4): 810.     CrossRef
  • Advancements in the Diagnosis of Gastric Subepithelial Tumors
    Osamu Goto, Mitsuru Kaise, Katsuhiko Iwakiri
    Gut and Liver.2022; 16(3): 321.     CrossRef
  • Mucosal Incision-Assisted Endoscopic Biopsy as an Alternative to Endoscopic Ultrasound-Guided Fine-Needle Aspiration/Biopsy for Gastric Subepithelial Tumor
    Cheol Woong Choi, Joo Ha Hwang
    Clinical Endoscopy.2020; 53(5): 505.     CrossRef
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Modified Endoscopic Ultrasound Needle to Obtain Histological Core Tissue Samples: A Retrospective Analysis
Munish Ashat, Kaartik Soota, Jagpal S. Klair, Sarika Gupta, Chris Jensen, Arvind R. Murali, Randhir Jesudoss, Rami El-Abiad, Henning Gerke
Clin Endosc 2020;53(4):471-479.   Published online February 5, 2020
DOI: https://doi.org/10.5946/ce.2019.108
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound (EUS)-guided fine-needle aspiration is very effective for providing specimens for cytological evaluation. However, the ability to provide sufficient tissue for histological evaluation has been challenging due to the technical limitations of dedicated core biopsy needles. Recently, a modified EUS needle has been introduced to obtain tissue core samples for histological analysis. We aimed to determine (1) its ability to obtain specimens for histological assessment and (2) the diagnostic accuracy of EUS-guided fine-needle biopsy (EUS-FNB) using this needle.
Methods
We retrospectively analyzed consecutive cases of FNB using modified EUS needles for 342 lesions in 303 patients. The cytology and histological specimens were analyzed. Diagnostic accuracy was calculated.
Results
Adequate cytological and histological assessment was possible in 293/342 (86%) and 264/342 (77%) lesions, respectively. Diagnostic accuracy of the cytological specimen was 294/342 (86%) versus 254/342 (74%) for the histological specimen (p<0.01). Diagnostic accuracy of the combined cytological and histological assessment was 323/342 (94.4%), which was significantly higher than that of both histology alone (p<0.001) and cytology alone (p=0.001).
Conclusions
EUS-FNB with the modified EUS needle provided histologic tissue cores in the majority of cases and achieved excellent diagnostic accuracy with few needle passes.

Citations

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  • Randomized trial comparing the Franseen needle versus 2 types of sharpened-tip 3-prong needles in EUS-guided tissue acquisition from solid pancreatic lesions
    Takuya Ishikawa, Hirotaka Suzuki, Yasuki Hori, Jun Yashika, Hiroki Suhara, Hajime Sumi, Masahiko Ando, Yachiyo Kuwatsuka, Kentaro Yamao, Yasuyuki Mizutani, Tadashi Iida, Kota Uetsuki, Takeshi Yamamura, Kazuhiro Furukawa, Masanao Nakamura, Hiromi Kataoka,
    Gastrointestinal Endoscopy.2025;[Epub]     CrossRef
  • Effect of wet-heparinized suction on the quality of mediastinal solid tumor specimens obtained by endoscopic ultrasound-guided fine-needle aspiration: a retrospective study from a single center
    Bo Xu, Qian Lu, Rong Fang, Xiaojuan Dai, Haiyan Xu, Xiangwu Ding, Huawei Gui
    BMC Gastroenterology.2023;[Epub]     CrossRef
  • Randomized controlled trial comparing the Franseen needle with the Fork-tip needle for EUS-guided fine-needle biopsy
    Munish Ashat, Jagpal S. Klair, Sydney L. Rooney, Sagar J. Vishal, Chris Jensen, Nadav Sahar, Arvind R. Murali, Rami El-Abiad, Henning Gerke
    Gastrointestinal Endoscopy.2021; 93(1): 140.     CrossRef
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Endoscopic Ultrasound Fine-Needle Aspiration versus Fine-Needle Biopsy for Lymph Node Diagnosis: A Large Multicenter Comparative Analysis
Diogo Turiani Hourneaux de Moura, Thomas R. McCarty, Pichamol Jirapinyo, Igor Braga Ribeiro, Galileu Ferreira Ayala Farias, Marvin Ryou, Linda S. Lee, Christopher C. Thompson
Clin Endosc 2020;53(5):600-610.   Published online December 3, 2019
DOI: https://doi.org/10.5946/ce.2019.170
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound fine-needle aspiration (EUS-FNA) is preferred for sampling of lymph nodes (LNs) adjacent to the gastrointestinal wall; however, fine-needle biopsy (FNB) may provide improved diagnostic outcomes. This study aimed to evaluate the comparative efficacy and safety of FNA versus FNB for LN sampling.
Methods
This was a multicenter retrospective study of prospectively collected data to evaluate outcomes of EUS-FNA and EUS-FNB for LN sampling. Characteristics analyzed included sensitivity, specificity, accuracy, the number of needle passes, diagnostic adequacy of rapid on-site evaluation (ROSE), cell-block analysis, and adverse events.
Results
A total of 209 patients underwent EUS-guided LN sampling. The mean lesion size was 16.22±8.03 mm, with similar sensitivity and accuracy between FNA and FNB ([67.21% vs. 75.00%, respectively, p=0.216] and [78.80% vs. 83.17%, respectively, p=0.423]). The specificity of FNB was better than that of FNA (100.00% vs. 93.62%, p=0.01). The number of passes required for diagnosis was not different. Abdominal and peri-hepatic LN location demonstrated FNB to have a higher sensitivity (81.08% vs. 64.71%, p=0.031 and 80.95% vs. 58.33%, p=0.023) and accuracy (88.14% vs. 75.29%, p=0.053 and 88.89% vs. 70.49%, p=0.038), respectively. ROSE was a significant predictor for accuracy (odds ratio, 5.16; 95% confidence interval, 1.15–23.08; p=0.032). No adverse events were reported in either cohort.
Conclusions
Both EUS-FNA and EUS-FNB are safe for the diagnosis of LNs. EUS-FNB is preferred for abdominal LN sampling. EUSFNA+ ROSE was similar to EUS-FNB alone, showing better diagnosis for EUS-FNB than traditional FNA. While ROSE remained a significant predictor for accuracy, due to its poor availability in most centers, its use may be limited to cases with previous inconclusive diagnoses.

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  • Lymphadenopathy Tissue Sampling by EUS-Guided Fine-Needle Biopsy Contributes to Meeting the Conditions for Genomic Profiling
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  • Endoscopic ultrasound-guided tissue sampling: European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review
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    Digestive Endoscopy.2025;[Epub]     CrossRef
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  • Comparing the diagnostic adequacy of 25-Gauge fork-tip versus franseen versus reverse-bevel-type needles in EUS–guided tissue acquisition: A prospective randomized study with a retrospective control
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  • Experience of Endoscopic Ultrasound Guided Fine Needle Aspiration and Fine Needle Biopsy: Data from Tertiary Care Hospital in Pakistan
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    Pakistan Journal of Health Sciences.2024; : 31.     CrossRef
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    Diagnostics.2023; 13(17): 2839.     CrossRef
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Focused review series
Present and Future of Endoscopic Ultrasound-Guided Tissue Acquisition in Solid Pancreatic Tumors
Jae Keun Park, Kwang Hyuck Lee
Clin Endosc 2019;52(6):541-548.   Published online November 29, 2019
DOI: https://doi.org/10.5946/ce.2019.127
AbstractAbstract PDFPubReaderePub
Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is a well-established method for pathological diagnosis of solid pancreatic neoplasm. It can be performed either as EUS-guided fine-needle aspiration (EUS-FNA) or EUS-guided fine-needle biopsy (EUSFNB). The incidence of adverse events related to EUS-TA is less than 1%. The factors that affect the diagnostic accuracy and specimen adequacy include the techniques used, type and size of the needle, competency of endosonographers, presence of cytopathologists/ cytotechnologists, and rapid on-site examination. EUS-TA may contribute to precision medicine through obtaining tissue samples for next-generation sequencing. The current status, several clinical issues for diagnostic yield and adverse events, and future perspectives of EUS-FNA/FNB for diagnosing pancreatic neoplasm have been discussed in this review article.

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  • A Novel Diagnostic Model of Biomarkers in the Washing Fluid Obtained by EUS-FNA in Pancreatic Cancer
    Chen-Fan Li, Lan-Xiang Hao, Yi-Jia Chen, En-De Lin, Chun-Ping Zhang, Li-Hua Wu, Xu-Ying Liao, Jia-Li Zhou, Jian-Hui Zhu, Ling-Hui Zhan, Xian-Ming Liang, Yi-Qun Hu
    Journal of Gastrointestinal Cancer.2025;[Epub]     CrossRef
  • Diagnostic performance of EUS-guided tissue acquisition for solid pancreatic lesions ≤10 mm
    Yuki Kawasaki, Susumu Hijioka, Yoshikuni Nagashio, Akihiro Ohba, Yuta Maruki, Kotaro Takeshita, Tetsuro Takasaki, Daiki Agarie, Yuya Hagiwara, Hidenobu Hara, Kohei Okamoto, Daiki Yamashige, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Takahiro Mizui, Ta
    Endoscopic Ultrasound.2024; 13(2): 115.     CrossRef
  • A combination of faecal and intratumour microbial community profiling reveals novel diagnostic and prognostic biomarkers for pancreatic tumours
    Wei Wang, Cheng Qian, Ting Wang, Yuetong Jiang, Yiran Zhou, Kaiyu Liu, Zhiyang Ma, Pengyi Liu, Yichi Wu, Leying Chen, Huaizhi Wang, Tingting Zhou
    Clinical and Translational Medicine.2024;[Epub]     CrossRef
  • Molecular Characterization and Xenotransplantation of Pancreatic Cancer Using Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA)
    Lilia Antonova, Piriya Paramanthan, Theresa Falls, Marie-Eve Wedge, Justin Mayer, Harman S. Sekhon, John McPherson, Robert E. Denroche, Steven Gallinger, John Cameron Bell, Carolina S. Ilkow, Avijit Chatterjee
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    Clinical Journal of Gastroenterology.2024; 17(6): 1111.     CrossRef
  • How to optimize the diagnostic yield of endoscopic ultrasound-guided fine-needle sampling in solid pancreatic lesions from a technical perspective
    Nam Hee Kim, Hong Joo Kim
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  • Efficacy of endoscopic ultrasound-guided tissue acquisition for solid pancreatic lesions 20 mm or less in diameter suspected as neuroendocrine tumors or requiring differentiation
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    Journal of Gastroenterology.2023; 58(7): 693.     CrossRef
  • Performance of EUS-FNB in solid pancreatic masses: a lesson from 463 consecutive procedures and a practical nomogram
    Nico Pagano, Claudio Ricci, Carlo Ingaldi, Sinan Sadalla, Andrea Fabbri, Laura Alberici, Giovanna Impellizeri, Socrate Pallio, Rocco Maurizio Zagari, Antonio De Leo, Matteo Cescon, Riccardo Casadei
    Updates in Surgery.2022; 74(3): 945.     CrossRef
  • Diagnostic Value and Influencing Factors of EUS-FNA in Pancreatic Solid Masses
    培君 任
    Advances in Clinical Medicine.2022; 12(05): 3931.     CrossRef
  • Diagnostic performance of endoscopic ultrasound-guided tissue acquisition by EUS-FNA versus EUS-FNB for solid pancreatic mass without ROSE: a retrospective study
    Thanawin Wong, Tanawat Pattarapuntakul, Nisa Netinatsunton, Bancha Ovartlarnporn, Jaksin Sottisuporn, Naichaya Chamroonkul, Pimsiri Sripongpun, Sawangpong Jandee, Apichat Kaewdech, Siriboon Attasaranya, Teerha Piratvisuth
    World Journal of Surgical Oncology.2022;[Epub]     CrossRef
  • Safety and Efficacy of Ultrasound-Guided Percutaneous Core Needle Biopsy of Pancreatic and Peripancreatic Lesions Adjacent to Critical Vessels
    Sun Hwa Chung, Hyun Ji Kang, Hyo Jeong Lee, Jin Sil Kim, Jeong Kyong Lee
    Journal of the Korean Society of Radiology.2021; 82(5): 1207.     CrossRef
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Case Reports
An Unusual Presentation of a Solid Pseudopapillary Tumor of the Pancreas Mimicking Adenocarcinoma
Hyung Ku Chon, Keum Ha Choi, Tae Hyeon Kim
Clin Endosc 2020;53(5):615-619.   Published online November 22, 2019
DOI: https://doi.org/10.5946/ce.2019.158
AbstractAbstract PDFPubReaderePub
Solid pseudopapillary tumors of the pancreas are rare and typically occur in young women. Compared with pancreatic adenocarcinoma, solid pseudopapillary tumors are characterized by notable indolent biological behavior associated with a favorable prognosis. Despite their large size, these tumors rarely metastasize. Even in cases of hepatic metastasis, most lesions are usually solitary in distribution and are amenable to resection. We report a case of a 55-year-old man with a small solid pseudopapillary tumor (≤3-cm diameter) mimicking a pancreatic adenocarcinoma, with multiple hepatic metastases. The diagnosis was confirmed by endoscopic ultrasound-guided fine-needle biopsy using a 22-G core needle. Unfortunately, rapid tumor progression led to patient mortality 5 months after diagnosis. To our knowledge, this is the first case report that describes a small solid pseudopapillary tumor of the pancreas with multiple hepatic metastasis and poor prognosis in a patient who was diagnosed with this condition at the time of initial diagnosis.

Citations

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  • Solid pseudopapillary neoplasm of the pancreas in an adolescent: A case report and review of the literature
    Aakriti Sapkota, Rajesh Paudel, Sandip Pandey, Navin Bhatt
    World Journal of Gastrointestinal Oncology.2025;[Epub]     CrossRef
  • Rare case of solid pseudopapillary neoplasm of the pancreas with liver and splenic metastasis in a 19-year-old girl
    Chi-Chi Chen, Ting-Yuan Feng, Hsiang-Chun Jan, Shaw-Jiun Chou, Tzu-Hung Chen, Sheng-Chun Wang
    International Journal of Surgery Case Reports.2024; 120: 109867.     CrossRef
  • Large Solid Pseudopapillary Tumor Pancreas with Extensive Splenoportal Thrombosis and Malignant Transformation—A Rare Entity
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  • Aggressive solid pseudopapillary tumor of the pancreas. (Literature review and case report)
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    Onkologiya. Zhurnal imeni P.A.Gertsena.2022; 11(2): 52.     CrossRef
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  • 148 Download
  • 4 Web of Science
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Submucosal Tunneling Muscle Biopsy for Esophageal Motility Disorders: A Case Report
Aleksandr A. Smirnov, Maya M. Kiriltseva, Aleksandr N. Burakov, Maksim V. Maksimov, Anna V. Botina, Marina M. Saadulaeva, Nadezda V. Konkina
Clin Endosc 2020;53(3):370-373.   Published online August 20, 2019
DOI: https://doi.org/10.5946/ce.2019.109
AbstractAbstract PDFPubReaderePub
Submucosal tunneling endoscopic technique can be useful in obtaining esophageal muscle specimens in patients with esophageal motility disorders. Here, we describe the case of a patient with systemic sclerosis. Histological verification of the esophageal involvement in the pathological process was required for the treatment. There were no intra- and post- operational complications.

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  • Updates in the Field of Submucosal Endoscopy
    Tadateru Maehata, Yoshinori Sato, Yusuke Nakamoto, Masaki Kato, Akiyo Kawashima, Hirofumi Kiyokawa, Hiroshi Yasuda, Hiroyuki Yamamoto, Keisuke Tateishi
    Life.2022; 13(1): 104.     CrossRef
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Original Articles
Endoscopic Ultrasound-Guided Liver Biopsy Using a Core Needle for Hepatic Solid Mass
Hyung Ku Chon, Hee Chan Yang, Keum Ha Choi, Tae Hyeon Kim
Clin Endosc 2019;52(4):340-346.   Published online July 15, 2019
DOI: https://doi.org/10.5946/ce.2018.175
AbstractAbstract PDFPubReaderePub
Background
/Aims: This study aimed to evaluate the feasibility and efficacy of endoscopic ultrasound-guided fine needle biopsy (EUSFNB) using a core needle for hepatic solid masses (HSMs). Additionally, the study aimed to assess factors that influence the diagnostic accuracy of EUS-FNB for HSMs.
Methods
A retrospective analysis of patients who underwent EUS-FNB for the pathological diagnosis of HSMs was conducted between January 2013 and July 2017. The procedure had been performed using core needles of different calibers. The assessed variables were mass size, puncture route, needle type, and the number of needle passes.
Results
Fifty-eight patients underwent EUS-FNB for the pathologic evaluation of HSMs with a mean mass size of 21.4±9.2 mm. EUSFNB was performed with either a 20-G (n=14), 22-G (n=29) or a 25-G core needle (n=15). The diagnostic accuracy for this procedure was 89.7%, but both specimen adequacy for histology and available immunohistochemistry stain were 91.4%. The sensitivity and specificity of EUS-FNB were 89.7% and 100%, respectively. There was one case involving bleeding as a complication, which was controlled with endoscopic hemostasis. According to the multivariate analysis, no variable was independently associated with a correct final diagnosis.
Conclusions
EUS-FNB with core biopsy needle is a safe and highly accurate diagnostic option for assessing HSMs. There were no variable factors associated with diagnostic accuracy.

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  • Endoscopic ultrasound‐guided tissue acquisition for focal liver lesions in patients with a history of multiple primary malignant neoplasms
    Yuichi Takano, Naoki Tamai, Masataka Yamawaki, Jun Noda, Tetsushi Azami, Fumitaka Niiya, Fumiya Nishimoto, Naotaka Maruoka, Tatsuya Yamagami, Masatsugu Nagahama
    DEN Open.2025;[Epub]     CrossRef
  • The outcomes of endoscopic ultrasound‐guided tissue acquisition for small focal liver lesions measuring ≤2 cm
    Yuichi Takano, Naoki Tamai, Masataka Yamawaki, Jun Noda, Tetsushi Azami, Fumitaka Niiya, Fumiya Nishimoto, Naotaka Maruoka, Tatsuya Yamagami, Masatsugu Nagahama
    DEN Open.2025;[Epub]     CrossRef
  • Endohepatology
    Nicole Ferrante, Kalyan Ram Bhamidimarri, Sunil Amin
    Clinics in Liver Disease.2025; 29(2): 253.     CrossRef
  • Diagnostic and therapeutic role of endoscopic ultrasound in liver diseases: A systematic review and meta-analysis
    Eyad Gadour, Abeer Awad, Zeinab Hassan, Khalid Jebril Shrwani, Bogdan Miutescu, Hussein Hassan Okasha
    World Journal of Gastroenterology.2024; 30(7): 742.     CrossRef
  • Endoscopic Ultrasound-Guided Fine Needle Biopsy of Focal Liver Lesions: An Effective Mini-Invasive Alternative to the Percutaneous Approach
    Gabriele Rancatore, Dario Ligresti, Giacomo Emanuele Maria Rizzo, Lucio Carrozza, Mario Traina, Ilaria Tarantino
    Diagnostics.2024; 14(13): 1336.     CrossRef
  • Endoscopic Ultrasound-Guided Tissue Sampling for the Cytohistological Diagnosis of Focal Liver Lesions
    Jose Lariño-Noia, Andrea Jardi-Cuadrado, Juan Enrique Dominguez-Muñoz, Yessica Domínguez-Novoa, Marco Galego, Alberto Rama, Daniel de la Iglesia-Garcia, Xurxo Martinez-Seara, Ihab Abdulkader-Nallib, Julio Iglesias-Garcia
    Diagnostics.2024; 14(11): 1155.     CrossRef
  • Role of Core Needle Biopsy in Liver Metastases: A Histopathological and Immunohistochemical Approach
    Zahraa Osama Yahiya, Zainab Waleed Aziz, Wahda Mohammed Taib Al-Nuaimy
    Medical Journal of Babylon.2024; 21(3): 572.     CrossRef
  • Endoscopic ultrasound-guided tissue acquisition for focal liver lesions can be safely performed in patients with ascites
    Yuichi Takano, Naoki Tamai, Masataka Yamawaki, Jun Noda, Tetsushi Azami, Fumitaka Niiya, Fumiya Nishimoto, Naotaka Maruoka, Tatsuya Yamagami, Masatsugu Nagahama
    Endoscopy International Open.2024; 12(11): E1309.     CrossRef
  • Role of endoscopic ultrasound and endoscopic ultrasound-guided tissue acquisition in diagnosing hepatic focal lesions
    Hussein Hassan Okasha, Hanane Delsa, Abdelmoneim Alsawaf, Ahmed Morad Hashim, Hani M Khattab, Dalia Abdelfatah, Abeer Abdellatef, Amr Albitar
    World Journal of Methodology.2023; 13(4): 287.     CrossRef
  • Endo-Hepatology: The Buzz Goes Much beyond Liver Biopsy—A Narrative Review
    Rajesh Puri, Zubin Sharma, Swapnil Dhampalwar, Abhishek Kathuria, Bimal Sahu
    Journal of Digestive Endoscopy.2023; 14(04): 227.     CrossRef
  • A comparison of the antegrade core trap and reverse bevel needles for EUS-guided fine-needle biopsy sampling of liver mass: a prospective randomized cross over study
    Pradermchai Kongkam, Nutbordee Nalinthassanai, Piyapan Prueksapanich, Anapat Sanpavat, Arlyn R. Cañones, Thanawat Luangsukrerk, Phonthep Angsuwatcharakon, Wiriyaporn Ridtitid, Pinit Kullavanijaya, Sombat Treeprasertsuk, Rungsun Rerknimitr
    HPB.2022; 24(6): 797.     CrossRef
  • Alternativen histologischer Materialgewinnung – Wann und wie ist die histologische Sicherung mittels Ultraschall (US), Computertomografie (CT) oder Endosonografie (EUS) sinnvoll?
    Kathleen Möller, Christoph F. Dietrich, Siegbert Faiss, Sven Mutze, Leonie Goelz
    Zeitschrift für Gastroenterologie.2022; 60(06): 937.     CrossRef
  • Ranunculus ternatus Thunb extract attenuates renal fibrosis of diabetic nephropathy via inhibiting SMYD2
    Weiwei Xu, Rui Peng, Siyu Chen, Congcong Wu, Xiaoxiao Wang, Ting Yu, Jiuying Jian, Ni Zhang, Siyang Zuo, Min Chen, Bing Guo, Lirong Liu
    Pharmaceutical Biology.2022; 60(1): 300.     CrossRef
  • Update on endoscopic ultrasound-guided liver biopsy
    Shiva Rangwani, Devarshi R Ardeshna, Khalid Mumtaz, Sean G Kelly, Samuel Y Han, Somashekar G Krishna
    World Journal of Gastroenterology.2022; 28(28): 3586.     CrossRef
  • Endoscopic Ultrasound-Guided Fine-Needle Biopsy versus Fine-Needle Aspiration in the Diagnosis of Focal Liver Lesions: Prospective Head-to-Head Comparison
    Marcel Gheorghiu, Andrada Seicean, Sorana D. Bolboacă, Ioana Rusu, Radu Seicean, Cristina Pojoga, Ofelia Moșteanu, Zeno Sparchez
    Diagnostics.2022; 12(9): 2214.     CrossRef
  • Diagnostic and interventional EUS in hepatology: An updated review
    Vaneet Jearth, Sridhar Sundaram, Surinder Singh Rana
    Endoscopic Ultrasound.2022; 11(5): 355.     CrossRef
  • Endoscopic ultrasound guided hepatic interventions
    Rintaro Hashimoto, Kenneth J. Chang
    Digestive Endoscopy.2021; 33(1): 54.     CrossRef
  • Biopsy or cytology for diagnosing hepatic focal lesions?
    Haeryoung Kim
    Clinical and Molecular Hepatology.2021; 27(2): 278.     CrossRef
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration Using a 22-G Needle for Hepatic Lesions: Single-Center Experience
    Ebru Akay, Deniz Atasoy, Engin Altınkaya, Ali Koç, Tamer Ertan, Hatice Karaman, Erkan Caglar
    Clinical Endoscopy.2021; 54(3): 404.     CrossRef
  • Role of Endoscopic Ultrasound in Liver Disease: Where Do We Stand?
    Tajana Pavic, Ivana Mikolasevic, Dominik Kralj, Nina Blazevic, Anita Skrtic, Ivan Budimir, Ivan Lerotic, Davor Hrabar
    Diagnostics.2021; 11(11): 2021.     CrossRef
  • Role of endoscopic ultrasound in the field of hepatology: Recent advances and future trends
    Jahnvi Dhar, Jayanta Samanta
    World Journal of Hepatology.2021; 13(11): 1459.     CrossRef
  • The utility of liver biopsy in 2020
    Ali Khalifa, Don C. Rockey
    Current Opinion in Gastroenterology.2020; 36(3): 184.     CrossRef
  • A State-of-the-Art Review on the Evolving Utility of Endoscopic Ultrasound in Liver Diseases Diagnosis
    Wisam Sbeit, Anas Kadah, Mahmud Mahamid, Rinaldo Pellicano, Amir Mari, Tawfik Khoury
    Diagnostics.2020; 10(8): 512.     CrossRef
  • A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management
    Wisam Sbeit, Anas Kadah, Amir Mari, Mahmud Mahamid, Tawfik Khoury
    Diagnostics.2020; 10(9): 688.     CrossRef
  • Endoscopic Ultrasound-Guided Liver Biopsies: Is the Future Here Yet?
    Ihab I. El Hajj, Mohammad Al-Haddad
    Clinical Endoscopy.2019; 52(4): 297.     CrossRef
  • 6,616 View
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  • 25 Web of Science
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Comparison of Endoscopic Ultrasound Biopsy Needles for Endoscopic Ultrasound-Guided Liver Biopsy
Armen Eskandari, Patrick Koo, Heejung Bang, Dorina Gui, Shiro Urayama
Clin Endosc 2019;52(4):347-352.   Published online July 10, 2019
DOI: https://doi.org/10.5946/ce.2019.005
AbstractAbstract PDFPubReaderePub
Background
/Aims: To compare the performance of latest commercially available endoscopic ultrasound biopsy needles.
Methods
Six latest commercially available needles were tested on a freshly harvested bovine liver; the tested needles included three 19 G, one 20 G, and two 22 G needles. Five biopsies were performed per needle with 10 mL of wet suction. The primary outcome was the number of complete portal tracts (CPTs) per needle aspirate. The secondary outcomes were the mean specimen length and mean fragment length. Analysis of variance and Tukey’s test were applied.
Results
All 19 G needles and the 20 G needle yielded similar mean CPTs and were superior to the SharkCore 22 G needle (p<0.001 adjusted for multiplicity). There was no statistically significant difference in total specimen length among the three 19 G needles and the 20 G needle tested. The two 22 G needles performed similarly with respect to the number of CPTs, mean fragment length, and mean specimen length (adjusted p=0.07, p=0.59, and p=0.10, respectively).
Conclusions
The specimen adequacy was similar among the 3 latest commercially available 19 G needles. The endoscopist may choose a larger-bore needle based on availability without concerns of specimen adequacy. Further studies are needed to assess the ease of needle use in various anatomical locations and to confirm the optimal needle design.

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  • Endoscopic ultrasound guided liver biopsy and portal pressure gradient: when, why and how? Can it become the standard of care in endo-hepatology?
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    Expert Review of Gastroenterology & Hepatology.2025; 19(3): 311.     CrossRef
  • Comparison of Franseen and novel tricore needles for endoscopic ultrasound-guided fine-needle biopsy in a porcine liver model
    Yubeen Park, Jeon Min Kang, Ji Won Kim, Dong-Sung Won, Dae Sung Ryu, Song Hee Kim, Chae Eun Yun, Seung Jin Eo, Jung-Hoon Park, Sang Soo Lee
    Scientific Reports.2024;[Epub]     CrossRef
  • EUS-guided versus percutaneous liver biopsy: A comprehensive review and meta-analysis of outcomes
    Saurabh Chandan, Smit Deliwala, Shahab R. Khan, Babu P. Mohan, Banreet S. Dhindsa, Jay Bapaye, Hemant Goyal, Lena L. Kassab, Faisal Kamal, Harlan R. Sayles, Gursimran S. Kochhar, Douglas G. Adler
    Endoscopic Ultrasound.2023; 12(2): 171.     CrossRef
  • The Role of Endoscopic Ultrasound in Hepatology
    Saleh A. Alqahtani, Floriane Ausloos, Ji Seok Park, Sunguk Jang
    Gut and Liver.2023; 17(2): 204.     CrossRef
  • EUS Guided Liver Biopsy
    Itegbemie Obaitan, Romil Saxena, Mohammad A Al-Haddad
    Techniques and Innovations in Gastrointestinal Endoscopy.2022; 24(1): 66.     CrossRef
  • Endoscopic Ultrasound-Guided Liver Biopsy
    Ishaan K. Madhok, Nasim Parsa, Jose M. Nieto
    Clinics in Liver Disease.2022; 26(1): 127.     CrossRef
  • Role of endoscopic ultrasound-guided liver biopsy: a meta-analysis
    Keyu Zeng, Zhenpeng Jiang, Jie Yang, Kefei Chen, Qiang Lu
    Scandinavian Journal of Gastroenterology.2022; 57(5): 545.     CrossRef
  • Update on endoscopic ultrasound-guided liver biopsy
    Shiva Rangwani, Devarshi R Ardeshna, Khalid Mumtaz, Sean G Kelly, Samuel Y Han, Somashekar G Krishna
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    Vaneet Jearth, Sridhar Sundaram, Surinder Singh Rana
    Endoscopic Ultrasound.2022; 11(5): 355.     CrossRef
  • Endoscopic ultrasound guided hepatic interventions
    Rintaro Hashimoto, Kenneth J. Chang
    Digestive Endoscopy.2021; 33(1): 54.     CrossRef
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    Digestive Diseases and Sciences.2021; 66(5): 1700.     CrossRef
  • Emerging role of endoscopic ultrasound-guided liver biopsy
    John David Chetwood, Sanjivan Mudaliar, Dominic Staudenmann, Joo-Shik Shin, Ken Liu, Avik Majumdar, Arthur Kaffes, Simone Strasser, Geoffrey W McCaughan, Payal Saxena
    Gut.2021; 70(8): 1600.     CrossRef
  • A prospective, head-to-head comparison of 2 EUS-guided liver biopsy needles in vivo
    Soorya N. Aggarwal, Travis Magdaleno, Farina Klocksieben, Jennifer E. MacFarlan, Shanth Goonewardene, Zachary Zator, Shashin Shah, Hiral N. Shah
    Gastrointestinal Endoscopy.2021; 93(5): 1133.     CrossRef
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration Using a 22-G Needle for Hepatic Lesions: Single-Center Experience
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    Clinical Endoscopy.2021; 54(3): 404.     CrossRef
  • How Can We Optimize Tools and Techniques for Endoscopic Ultrasound–Guided Liver Biopsy?
    Itegbemie Obaitan, Mohammad A. Al-Haddad
    Clinical Gastroenterology and Hepatology.2020; 18(5): 1025.     CrossRef
  • Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology
    James Neuberger, Jai Patel, Helen Caldwell, Susan Davies, Vanessa Hebditch, Coral Hollywood, Stefan Hubscher, Salil Karkhanis, Will Lester, Nicholas Roslund, Rebecca West, Judith I Wyatt, Mathis Heydtmann
    Gut.2020; 69(8): 1382.     CrossRef
  • Endoscopic ultrasound in chronic liver disease
    Brian M Fung, Alexander P Abadir, Armen Eskandari, Michael J Levy, James H Tabibian
    World Journal of Hepatology.2020; 12(6): 262.     CrossRef
  • Endoscopic Ultrasound-Guided Liver Biopsies: Is the Future Here Yet?
    Ihab I. El Hajj, Mohammad Al-Haddad
    Clinical Endoscopy.2019; 52(4): 297.     CrossRef
  • 8,209 View
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  • 21 Web of Science
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Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions
Ihab I. El Hajj, Howard Wu, Sarah Reuss, Melissa Randolph, Akeem Harris, Mark A. Gromski, Mohammad Al-Haddad
Clin Endosc 2018;51(6):576-583.   Published online July 13, 2018
DOI: https://doi.org/10.5946/ce.2018.053
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique.
Methods
Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the formal cytopathological diagnosis.
Results
Mean cell block histology scores were significantly higher (p=0.046) in the FNB group (51 samples) despite a significantly lower (p<0.001) mean number of passes compared to the FNA group (50 specimens). The overall diagnostic yields for the FNB vs. FNA groups were 96% vs. 88%. The degree of tumor differentiation was adequately assessed in all cell block qualifying lesions in the FNB group. Two patients developed post-FNB abdominal pain.
Conclusions
The new Franseen tip FNB device provides histologically superior and cytologically comparable specimens to those obtained by FNA, but with fewer passes.

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  • Adverse events of 20–22G second‐generation endoscopic ultrasound‐guided fine‐needle biopsy needles for solid lesions in the upper gastrointestinal tract and adjacent organs: Systematic review and meta‐analysis
    Cheng‐ye Pan, Shi‐min Wang, Dong‐hao Cai, Jia‐yi Ma, Shi‐yu Li, Yibin Guo, Sun Jing, Jin Zhendong, Kaixuan Wang
    Digestive Endoscopy.2025; 37(5): 490.     CrossRef
  • Real-Life Comparison of Diagnostic Yield and Sample Adequacy of 22 G and 25 G EBUS-TBNB Needles: A Retrospective Study
    Filippo Lanfranchi, George Kalak, Gioele Castelli, Laura Mancino, Gabriele Foltran, Alberto Pavan, Lorenzo Ciarrocchi, Licia Laurino, Lucio Michieletto
    Journal of Clinical Medicine.2025; 14(5): 1637.     CrossRef
  • Evaluation of the 22G Franseen needle and 22G Lancet needle for endoscopic ultrasonography-guided tissue acquisition sampling in solid pancreatic lesions: Propensity score weighting
    Yuki Ishikawa-Kakiya, Hirotsugu Maruyama, Kojiro Tanoue, Akira Higashimori, Masaki Ominami, Yuji Nadatani, Shusei Fukunaga, Koji Otani, Shuhei Hosomi, Fumio Tanaka, Yasuhiro Fujiwara, Kazunori Nagasaka
    PLOS One.2025; 20(5): e0322857.     CrossRef
  • Endoscopic ultrasound with bronchoscope fine-needle biopsy in the diagnosis of suspected malignant pulmonary lesions with crown-cut needle: a retrospective study
    Filippo LANFRANCHI, Gioele CASTELLI, Giacomo GIULIANELLI, Laura MANCINO, Gabriele FOLTRAN, Michele RIZZO, Federico FRACASSO, Alberto PAVAN, Lorenzo NICOLÈ, Licia LAURINO, Lucio MICHIELETTO
    Minerva Medica.2025;[Epub]     CrossRef
  • Consensus statements on endoscopic ultrasound‐guided tissue acquisition. Guidelines from the Asian Endoscopic Ultrasound Group
    Charing Ching‐Ning Chong, Rapat Pittayanon, Nonthalee Pausawasdi, Vikram Bhatia, Nozomi Okuno, Raymond Shing‐Yan Tang, Tsu‐Yao Cheng, Yu‐Ting Kuo, Dongwook Oh, Tae Jun Song, Tae Hyeon Kim, Kazuo Hara, Anthony Wing‐Hung Chan, Howard Ho Wai Leung, Aiming Ya
    Digestive Endoscopy.2024; 36(8): 871.     CrossRef
  • The World Health Organization Reporting System for Pancreaticobiliary Cytopathology: Overview and Summary
    Barbara A. Centeno, Mauro Saieg, Momin T. Siddiqui, Miguel Perez‐Machado, Lester J. Layfield, Birgit Weynand, Michelle D. Reid, Edward B. Stelow, Maria D. Lozano, Noriyoshi Fukushima, Ian A. Cree, Ravi Mehrotra, Fernando C. Schmitt, Andrew S. Field, Marth
    Cancer Cytopathology.2024; 132(7): 396.     CrossRef
  • Comparative diagnostic performance of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) versus endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) for tissue sampling of solid pancreatic and non-pancreatic lesions without ROSE: a prospec
    Hussein Hassan Okasha, Mohammed Yousri Ahmed, Marwa A. Ahmed, Sameh Abou Elenin, Abeer Abdel-latif, Mahmoud Farouk, Mahmoud Gamal Ameen, Ahmed Hussein El-Habashi, Mahasen Akram Elshaer, Ahmed Elsayed Alzamzamy
    The Egyptian Journal of Internal Medicine.2024;[Epub]     CrossRef
  • Franseen needle in endobronchial ultrasound-guided transbronchial needle aspiration: a phase II prospective study
    Kohei Shikano, Jun Ikari, Takahiro Nakajima, Masayuki Ota, Yuki Shiko, Akira Naito, Mitsuhiro Abe, Takeshi Kawasaki, Jun-Ichiro Ikeda, Yoshihito Ozawa, Takuji Suzuki
    Japanese Journal of Clinical Oncology.2024; 54(9): 1037.     CrossRef
  • Evaluation of Needles in Endoscopic Ultrasound-Guided Tissue Acquisition of Pancreatic Cancer for Genetic Yield and Quality
    Jonanthan Tiong, Phi Nguyen, Mithra Sritharan, Joanne Lundy, Henry Shen, Beena Kumar, Michael Swan, Brenda Jenkins, Daniel Croagh
    Cureus.2024;[Epub]     CrossRef
  • Pulmonary endoscopy – central to an interventional pulmonology program
    Sally Griffiths, Lucy Power, David Breen
    Expert Review of Respiratory Medicine.2024; 18(11): 843.     CrossRef
  • Endobronchial ultrasound bronchoscopy Franseen fine needle biopsy tool versus standard fine needle aspiration needle: Impact on diagnosis and tissue adequacy
    Matthew C. Aboudara, Timothy Saettele, Ossama Tawfik
    Respiratory Medicine.2023; 208: 107131.     CrossRef
  • Clinical Applications of Endobronchial Ultrasound (EBUS) Scope: Challenges and Opportunities
    Davide Biondini, Mariaenrica Tinè, Umberto Semenzato, Matteo Daverio, Francesca Scalvenzi, Erica Bazzan, Graziella Turato, Marco Damin, Paolo Spagnolo
    Diagnostics.2023; 13(15): 2565.     CrossRef
  • Endoscopic Ultrasound-Guided Fine Needle Biopsy in the Diagnostic Work-Up of Deep-Seated Lymphadenopathies and Spleen Lesions: A Monocentric Experience
    Flaminia Bellisario, Fabia Attili, Fabrizia Campana, Federica Borrelli de Andreis, Silvia Bellesi, Elena Maiolo, Eleonora Alma, Rosalia Malafronte, Giuseppe Macis, Luigi Maria Larocca, Salvatore Annunziata, Francesco D’Alò, Stefan Hohaus
    Diagnostics.2023; 13(17): 2839.     CrossRef
  • Fine needle biopsy versus fine needle aspiration in the diagnosis of immunohistochemistry-required lesions: A multicenter study with prospective evaluation
    Yuchong Zhao, Dingkun Xiong, Aruna, Qian Chen, Dong Kuang, Si Xiong, Yun Wang, Yilei Yang, Qiaozhen Guo, Lan Chen, Jiqiao Zhang, Xiaoli Wu, Yunlu Feng, Bin Cheng
    Endoscopic Ultrasound.2023; 12(6): 456.     CrossRef
  • A Systematic Review of Real-time Fine-needle Aspiration Biopsy Methods for Soft Tissues
    Rahul Nadda, Ashish Kumar Sahani, Ramjee Repaka
    IETE Technical Review.2022; 39(5): 1011.     CrossRef
  • Concordance of the histological diagnosis of type 1 autoimmune pancreatitis and its distinction from pancreatic ductal adenocarcinoma with endoscopic ultrasound-guided fine needle biopsy specimens: an interobserver agreement study
    Kenji Notohara, Terumi Kamisawa, Toru Furukawa, Noriyoshi Fukushima, Takeshi Uehara, Satomi Kasashima, Eisuke Iwasaki, Atsushi Kanno, Atsuhiro Kawashima, Kensuke Kubota, Yasuhiro Kuraishi, Masayo Motoya, Itaru Naitoh, Takayoshi Nishino, Junichi Sakagami,
    Virchows Archiv.2022; 480(3): 565.     CrossRef
  • Comparison of fine-needle aspiration and fine-needle biopsy devices for endoscopic ultrasound-guided sampling of solid lesions: a systemic review and meta-analysis
    Priscilla A. van Riet, Nicole S. Erler, Marco J. Bruno, Djuna L. Cahen
    Endoscopy.2021; 53(04): 411.     CrossRef
  • A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions
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    Gastroenterology Research and Practice.2021; 2021: 1.     CrossRef
  • Comparison of contrast-enhanced versus conventional EUS-guided FNA/fine-needle biopsy in diagnosis of solid pancreatic lesions: a randomized controlled trial
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    Gastrointestinal Endoscopy.2021; 94(2): 303.     CrossRef
  • A prospective multicenter study of endoscopic ultrasound‐guided fine needle biopsy using a 22‐gauge Franseen needle for pancreatic solid lesions
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    Journal of Gastroenterology and Hepatology.2021; 36(10): 2754.     CrossRef
  • Optimal number of needle punctures in endoscopic ultrasound-guided fine-needle biopsy for gastric subepithelial lesions without rapid on-site evaluation
    Masato Suzuki, Yusuke Sekino, Kunihiro Hosono, Kenichi Kawana, Hajime Nagase, Kensuke Kubota, Atsushi Nakajima
    Journal of Medical Ultrasonics.2021; 48(4): 623.     CrossRef
  • Comparison of Endoscopic Ultrasound-Guided Tissue Acquisition Using a 20-Gauge Menghini Needle with a Lateral Forward Bevel and a 22-Gauge Franseen Needle: A Single-Center Large Cohort Study
    Takafumi Mie, Takashi Sasaki, Ryo Kanata, Takaaki Furukawa, Tsuyoshi Takeda, Akiyoshi Kasuga, Masato Matsuyama, Masato Ozaka, Naoki Sasahira
    Clinical Endoscopy.2021; 54(5): 730.     CrossRef
  • Usefulness of a Fork-Tip Needle in Endoscopic Ultrasound-Guided Fine-Needle Biopsy for Gastric Subepithelial Lesions
    Mika Takasumi, Takuto Hikichi, Minami Hashimoto, Jun Nakamura, Tsunetaka Kato, Ryoichiro Kobashi, Takumi Yanagita, Rei Suzuki, Mitsuru Sugimoto, Yuki Sato, Hiroki Irie, Tadayuki Takagi, Masao Kobayakawa, Yuko Hashimoto, Hiromasa Ohira
    Diagnostics.2021; 11(10): 1883.     CrossRef
  • Endoscopic ultrasound fine needle aspiration vs fine needle biopsy in solid lesions: A multi-center analysis
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    Diagnostics.2021; 11(12): 2331.     CrossRef
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  • Factors associated with diagnostic accuracy, technical success and adverse events of endoscopic ultrasound‐guided fine‐needle biopsy: A systematic review and meta‐analysis
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    Journal of Gastroenterology and Hepatology.2020; 35(8): 1264.     CrossRef
  • An exclusive fine-needle biopsy approach to sampling solid lesions under EUS guidance: a prospective cohort study
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    Gastroenterology Report.2020; 8(5): 349.     CrossRef
  • Diagnostic efficacy of three suction techniques for endoscopic ultrasound-guided fine-needle biopsy of solid pancreatic lesions: protocol for a multicenter randomized cross-over clinical trial
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    Digestive and Liver Disease.2020; 52(7): 734.     CrossRef
  • Core needle biopsy with endobronchial ultrasonography: single center experience with 100 cases
    Akshu Balwan, Billie Bixby, Cassi Grotepas, Benjamin L. Witt, Aidin Iravani, Sikandar Ansari, Chakravarthy B. Reddy
    Journal of the American Society of Cytopathology.2020; 9(4): 249.     CrossRef
  • Current status of newer generation endoscopic ultrasound core needles in the diagnostic evaluation of gastrointestinal lesions
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  • Diagnostic yield of endoscopic ultrasound-guided tissue acquisition for small solid pancreatic lesions
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    Endoscopy International Open.2020; 08(10): E1359.     CrossRef
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    Clinical Endoscopy.2020; 53(5): 600.     CrossRef
  • Endoscopic ultrasound-fine needle biopsies of pancreatic lesions: Prospective study of histology quality using Franseen needle
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    World Journal of Gastroenterology.2020; 26(37): 5693.     CrossRef
  • Comparison of the reverse bevel versus Franseen type endoscopic ultrasound needle
    Chi Wing Chow, Syeda Asma Haider, Krish Ragunath, Guruprasad P Aithal, Martin W James, Jacobo Ortiz-Fernandez-Sordo, Aloysious Dominic Aravinthan, Suresh Vasan Venkatachalapathy
    World Journal of Gastrointestinal Endoscopy.2020; 12(9): 266.     CrossRef
  • Usefulness of endoscopic ultrasound-guided fine-needle biopsy for the diagnosis of autoimmune pancreatitis using a 22-gauge Franseen needle: a prospective multicenter study
    Takuya Ishikawa, Hiroki Kawashima, Eizaburo Ohno, Hiroki Suhara, Daijuro Hayashi, Takeshi Hiramatsu, Hiroshi Matsubara, Takahisa Suzuki, Takamichi Kuwahara, Eri Ishikawa, Yoshie Shimoyama, Fumie Kinoshita, Yoshiki Hirooka, Mitsuhiro Fujishiro
    Endoscopy.2020; 52(11): 978.     CrossRef
  • Overlooked risk for needle tract seeding following endoscopic ultrasound-guided minimally invasive tissue acquisition
    Ruo-Yu Gao, Ben-Hua Wu, Xin-Ying Shen, Tie-Li Peng, De-Feng Li, Cheng Wei, Zhi-Chao Yu, Ming-Han Luo, Feng Xiong, Li-Sheng Wang, Jun Yao
    World Journal of Gastroenterology.2020; 26(40): 6182.     CrossRef
  • Efficacy of EUS-guided FNB using a Franseen needle for tissue acquisition and microsatellite instability evaluation in unresectable pancreatic lesions
    Mitsuru Sugimoto, Hiroki Irie, Tadayuki Takagi, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Yuki Sato, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Yasuyuki Kobayashi, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira
    BMC Cancer.2020;[Epub]     CrossRef
  • Endoscopic Ultrasound-Guided Tissue Acquisition by 22-Gauge Franseen and Standard Needles for Solid Pancreatic Lesions
    Kazunaga Ishigaki, Yousuke Nakai, Hiroki Oyama, Sachiko Kanai, Tatsunori Suzuki, Tomoka Nakamura, Tatsuya Sato, Ryunosuke Hakuta, Kei Saito, Tomotaka Saito, Naminatsu Takahara, Tsuyoshi Hamada, Suguru Mizuno, Hirofumi Kogure, Minoru Tada, Hiroyuki Isayama
    Gut and Liver.2020; 14(6): 817.     CrossRef
  • Clinical Impact of EUS-Guided Fine Needle Biopsy Using a Novel Franseen Needle for Histological Assessment of Pancreatic Diseases
    Takuya Ishikawa, Hiroki Kawashima, Eizaburo Ohno, Hiroyuki Tanaka, Daisuke Sakai, Tadashi Iida, Ryo Nishio, Takeshi Yamamura, Kazuhiro Furukawa, Masanao Nakamura, Ryoji Miyahara, Senju Hashimoto, Masatoshi Ishigami, Yoshiki Hirooka
    Canadian Journal of Gastroenterology and Hepatology.2019; 2019: 1.     CrossRef
  • Recent advancement in EUS-guided fine needle sampling
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    Clinical Endoscopy.2019; 52(4): 297.     CrossRef
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    Clinical Endoscopy.2019; 52(6): 541.     CrossRef
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Mucosal Incision and Forceps Biopsy for Reliable Tissue Sampling of Gastric Subepithelial Tumors
Sa Young Shin, Sang Jin Lee, Jae Hyuck Jun, Jong Kyu Park, Hyun Il Seo, Koon Hee Han, Young Don Kim, Woo Jin Jeong, Gab Jin Cheon
Clin Endosc 2017;50(1):64-68.   Published online March 4, 2016
DOI: https://doi.org/10.5946/ce.2015.094
AbstractAbstract PDFPubReaderePub
Background
/Aims: The diagnostic efficacy of current tissue sampling techniques for gastric subepithelial tumors (SETs) is limited. Better tissue sampling techniques are needed to improve pathological diagnosis. The aim of this study was to evaluate the safety and efficacy of a new technique, mucosal incision and forceps biopsy, for reliable tissue sampling of gastric SETs.
Methods
This study enrolled 12 consecutive patients who underwent mucosal incision and forceps biopsy of gastric SETs between November 2011 and September 2014 at Gangneung Asan Hospital. The medical records of patients were reviewed retrospectively. The safety and diagnostic yield of this method were evaluated.
Results
By performing mucosal incision and forceps biopsy, we were able to provide a definitive histological diagnosis for 11 out of 12 cases. The pathological diagnoses were leiomyoma (3/11), gastrointestinal stromal tumor (GIST; 2/11), lipoma (2/11), schwannoma (1/11), and ectopic pancreas (3/11). In cases of leiomyoma (n=3) and GIST (n=2), tissue samples were of sufficient size to allow immunohistochemical staining. In addition, the mitotic index was evaluated in two cases of GIST. There were no procedure-related complications.
Conclusions
Mucosal incision and forceps biopsy can be used as one of several methods to obtain adequate tissue samples from gastric SETs.

Citations

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  • Diagnostic ability and adverse events of mucosal incision‐assisted biopsy for gastric subepithelial tumors: Systematic review and meta‐analysis
    Eriko Koizumi, Osamu Goto, Akihisa Matsuda, Toshiaki Otsuka, Yumiko Ishikawa, Shun Nakagome, Masahiro Niikawa, Tsugumi Habu, Keiichiro Yoshikata, Kumiko Kirita, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Jun Omori, Naohiko Akimoto, Hiroshi Yoshida, Kat
    Digestive Endoscopy.2025; 37(3): 236.     CrossRef
  • Approach to upper gastrointestinal subepithelial lesions
    Shrihari Anil Anikhindi, Rajesh Puri, Noriya Uedo, Kamlesh Taori, Anil Arora
    Expert Review of Gastroenterology & Hepatology.2025;[Epub]     CrossRef
  • Natural history of gastric leiomyoma
    Kwangbeom Park, Ji Yong Ahn, Hee Kyong Na, Kee Wook Jung, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwwon-Yong Jung
    Surgical Endoscopy.2024; 38(5): 2726.     CrossRef
  • Diagnostic yield of endoscopic and EUS-guided biopsy techniques in subepithelial lesions of the upper GI tract: a systematic review
    Cynthia A. Verloop, Jacqueline A.C. Goos, Marco J. Bruno, Rutger Quispel, Lydi M.J.W. van Driel, Lieke Hol
    Gastrointestinal Endoscopy.2024; 99(6): 895.     CrossRef
  • Advancements in the Diagnosis of Gastric Subepithelial Tumors
    Osamu Goto, Mitsuru Kaise, Katsuhiko Iwakiri
    Gut and Liver.2022; 16(3): 321.     CrossRef
  • Endoscopic full-thickness resection of gastric subepithelial tumors with the gFTRD-system: a prospective pilot study (RESET trial)
    Benjamin Meier, Arthur Schmidt, Nicolas Glaser, Alexander Meining, Benjamin Walter, Andreas Wannhoff, Bettina Riecken, Karel Caca
    Surgical Endoscopy.2020; 34(2): 853.     CrossRef
  • Comparison of the Diagnostic Ability of Endoscopic Ultrasonography and Abdominopelvic Computed Tomography in the Diagnosis of Gastric Subepithelial Tumors
    Sang Yoon Kim, Ki-Nam Shim, Joo-Ho Lee, Ji Young Lim, Tae Oh Kim, A. Reum Choe, Chung Hyun Tae, Hye-Kyung Jung, Chang Mo Moon, Seong-Eun Kim, Sung-Ae Jung
    Clinical Endoscopy.2019; 52(6): 565.     CrossRef
  • Diagnosis of Gastric Subepithelial Tumors Using Endoscopic Ultrasonography or Abdominopelvic Computed Tomography: Which is Better?
    Eun Young Park, Gwang Ha Kim
    Clinical Endoscopy.2019; 52(6): 519.     CrossRef
  • How Can We Obtain Tissue from a Subepithelial Lesion for Pathologic Diagnosis?
    Eun Young Kim
    Clinical Endoscopy.2017; 50(1): 6.     CrossRef
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Yields and Utility of Endoscopic Ultrasonography-Guided 19-Gauge Trucut Biopsy versus 22-Gauge Fine Needle Aspiration for Diagnosing Gastric Subepithelial Tumors
Hee Kyong Na, Jeong Hoon Lee, Young Soo Park, Ji Yong Ahn, Kwi-Sook Choi, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Jin-Ho Kim
Clin Endosc 2015;48(2):152-157.   Published online March 27, 2015
DOI: https://doi.org/10.5946/ce.2015.48.2.152
AbstractAbstract PDFPubReaderePub
Background/Aims

To evaluate the yields and utility of 19-gauge (G) Trucut biopsy (TCB) versus 22 G fine needle aspiration (FNA) for diagnosing gastric subepithelial tumors (SETs).

Methods

We retrieved data for 152 patients with a gastric SET larger than 2 cm who had undergone endoscopic ultrasonography (EUS)-guided 19 G TCB (n=90) or 22 G FNA (n=62). Relevant clinical, tumor-specific, and EUS procedural information was reviewed retrospectively.

Results

A specific diagnosis was made for 76 gastrointestinal stromal tumors (GISTs) and 51 non-GIST SETs. The diagnostic yield of TCB was greater than that of FNA (77.8% vs. 38.7%, p<0.001). The percentage of non-diagnostic specimens (suspicious and insufficient) was significantly lower in the TCB group (6.7% and 15.5%, respectively) than in the FNA group (22.6% and 38.7%, respectively; both p<0.001). TCB accurately diagnosed 90.9% of GISTs and 81.1% of non-GIST SETs, whereas FNA accurately diagnosed 68.8% of GISTs and 14.3% of non-GIST SETs. There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs. FNA, 3.3% vs. 8.1%; p=0.27).

Conclusions

Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.

Citations

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  • Natural history of gastric leiomyoma
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    Surgical Endoscopy.2024; 38(5): 2726.     CrossRef
  • Diagnostic yield of endoscopic and EUS-guided biopsy techniques in subepithelial lesions of the upper GI tract: a systematic review
    Cynthia A. Verloop, Jacqueline A.C. Goos, Marco J. Bruno, Rutger Quispel, Lydi M.J.W. van Driel, Lieke Hol
    Gastrointestinal Endoscopy.2024; 99(6): 895.     CrossRef
  • Comparison of endoscopic ultrasound‐guided fine needle aspiration cytology versus endoscopic biopsy for the diagnosis of subepithelial lesions of the upper and lower gastrointestinal tract: A 10‐year retrospective single institution analysis
    Katrina Collins, Bianca Puello Yocum, Hector Mesa, Harvey Cramer, Omer Saeed
    Diagnostic Cytopathology.2023; 51(7): 434.     CrossRef
  • Utility of endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB) for diagnosing small subepithelial lesions (< 20 mm)
    Masanari Sekine, Takaya Miura, Junichi Fujiwara, Takeshi Uehara, Takeharu Asano, Satohiro Matsumoto, Hiroyuki Miyatani, Hirosato Mashima
    Journal of Ultrasound.2022; 25(1): 35.     CrossRef
  • Advancements in the Diagnosis of Gastric Subepithelial Tumors
    Osamu Goto, Mitsuru Kaise, Katsuhiko Iwakiri
    Gut and Liver.2022; 16(3): 321.     CrossRef
  • Necessity of Individualized Approach for Gastric Subepithelial Tumor Considering Pathologic Discrepancy and Surgical Difficulty Depending on the Gastric Location
    Sung Gon Kim, Bang Wool Eom, Hongman Yoon, Myeong-Cheorl Kook, Young-Woo Kim, Keun Won Ryu
    Journal of Clinical Medicine.2022; 11(16): 4733.     CrossRef
  • Accuracy of visual on-site evaluation (Vose) In predicting the adequacy of Eus-guided fine needle biopsy: A single center prospective study
    Serena Stigliano, Valerio Balassone, Dario Biasutto, Francesco Covotta, Marianna Signoretti, Francesco Maria Di Matteo
    Pancreatology.2021; 21(1): 312.     CrossRef
  • Utility of a 20G needle with a core trap in EUS-guided fine-needle biopsy for gastric submucosal tumors: A multicentric prospective trial
    Ken Kamata, Akira Kurita, Satoru Yasukawa, Yasutaka Chiba, Hiroko Nebiki, Masanori Asada, Hiroaki Yasuda, Hideyuki Shiomi, Takeshi Ogura, Makoto Takaoka, Noriyuki Hoki, Reiko Ashida, Minoru Shigekawa, Akio Yanagisawa, Masatoshi Kudo, Masayuki Kitano
    Endoscopic Ultrasound.2021; 10(2): 134.     CrossRef
  • Endoscopic Resection of Gastrointestinal Stromal Tumor: Is It Safe?
    Moon Kyung Joo
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2021; 21(3): 180.     CrossRef
  • Efficacy of Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Gastric Subepithelial Tumors Located in the Cardia
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    Digestive Diseases and Sciences.2020; 65(2): 583.     CrossRef
  • Comparison of the treatment outcomes of endoscopic and surgical resection of GI stromal tumors in the stomach: a propensity score–matched case-control study
    Ga Hee Kim, Kee Don Choi, Chung Sik Gong, In-Seob Lee, Young Soo Park, Minkyu Han, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
    Gastrointestinal Endoscopy.2020; 91(3): 527.     CrossRef
  • EUS-guided fine-needle biopsy sampling versus FNA in the diagnosis of subepithelial lesions: a large multicenter study
    Diogo T.H. de Moura, Thomas R. McCarty, Pichamol Jirapinyo, Igor B. Ribeiro, Victor K. Flumignan, Fedaa Najdawai, Marvin Ryou, Linda S. Lee, Christopher C. Thompson
    Gastrointestinal Endoscopy.2020; 92(1): 108.     CrossRef

  • Gastrointestinal Stromal Tumors of the Small Intestine: Progress in Diagnosis and Treatment Research


    Fangxing Peng, Yao Liu
    Cancer Management and Research.2020; Volume 12: 3877.     CrossRef
  • Prospective, multicenter, observational study of tissue acquisition through EUS-guided fine-needle biopsy using a 25G Franseen needle
    Ryo Sugiura, Masaki Kuwatani, Kei Yane, Yoko Taya, Hideyuki Ihara, Manabu Onodera, Kazunori Eto, Itsuki Sano, Taiki Kudo, Tomoko Mitsuhashi, Akio Katanuma, Naoya Sakamoto
    Endoscopic Ultrasound.2019; 8(5): 321.     CrossRef
  • Randomized crossover trial comparing EUS‐guided fine‐needle aspiration with EUS‐guided fine‐needle biopsy for gastric subepithelial tumors
    Tomohisa Iwai, Mitsuhiro Kida, Hiroshi Imaizumi, Shiro Miyazawa, Kosuke Okuwaki, Hiroshi Yamauchi, Toru Kaneko, Rikiya Hasegawa, Eiji Miyata, Wasaburo Koizumi
    Diagnostic Cytopathology.2018; 46(3): 228.     CrossRef
  • Endoscopic ultrasound-guided tissue acquisition of subepithelial masses
    Jared J. Rejeski, Girish Mishra
    Techniques in Gastrointestinal Endoscopy.2018; 20(1): 15.     CrossRef
  • The diagnostic and cellularity yield of reverse bevel versus fork‐tip fine needle biopsy
    Mohamed M Abdelfatah, Ahmed Hamed, Nicholas J. Koutlas, F. Zahra Aly
    Diagnostic Cytopathology.2018; 46(8): 649.     CrossRef
  • Endobronchial Ultrasound-guided Transbronchial Needle Aspiration With a 19-G Needle Device
    Alain Tremblay, Seamus McFadden, Martina Bonifazi, Valentina Luzzi, Samuel V. Kemp, Stefano Gasparini, Alex Chee, Paul MacEachern, Elaine Dumoulin, Christopher A. Hergott, Pallav L. Shah
    Journal of Bronchology & Interventional Pulmonology.2018; 25(3): 218.     CrossRef
  • EUS-FNA WITH 19 OR 22 GAUGES NEEDLES FOR GASTRIC SUBEPITHELIAL LESIONS OF THE MUSCLE LAYER
    César Vivian LOPES, Antônio Atalíbio HARTMANN, Everson Luiz de Almeida ARTIFON
    ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo).2018;[Epub]     CrossRef
  • The role of EUS-guided fine needle aspiration in autoimmune pancreatitis: a single center prospective study
    Li Cao, Yun Wang, Jinlin Wang, Qiaozhen Guo, Qian Chen, Xiaoli Wu, Shou-Jiang Tang, Bin Cheng
    Scandinavian Journal of Gastroenterology.2018; 53(12): 1604.     CrossRef
  • Feasibility of a 20-gauge ProCore needle in EUS-guided subepithelial tumor sampling: a prospective multicenter study
    Do Hoon Kim, Gwang Ha Kim, Chang Min Cho, Chang Hwan Park, Soo-Young Na, Tae Hyeon Kim, Yu Kyung Cho, Ji Hyun Kim, Dong-Wan Seo
    BMC Gastroenterology.2018;[Epub]     CrossRef
  • Subepithelial rectal gastrointestinal stromal tumor – the use of endoscopic ultrasound-guided fine needle aspiration to establish a definitive cytological diagnosis: a case report
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    Journal of Medical Case Reports.2017;[Epub]     CrossRef
  • GEIS guidelines for gastrointestinal sarcomas (GIST)
    Andrés Poveda, Xavier García del Muro, Jose Antonio López-Guerrero, Ricardo Cubedo, Virginia Martínez, Ignacio Romero, César Serrano, Claudia Valverde, Javier Martín-Broto
    Cancer Treatment Reviews.2017; 55: 107.     CrossRef
  • The role of endoscopy in subepithelial lesions of the GI tract
    Ashley L. Faulx, Shivangi Kothari, Ruben D. Acosta, Deepak Agrawal, David H. Bruining, Vinay Chandrasekhara, Mohamad A. Eloubeidi, Robert D. Fanelli, Suryakanth R. Gurudu, Mouen A. Khashab, Jenifer R. Lightdale, V. Raman Muthusamy, Aasma Shaukat, Bashar J
    Gastrointestinal Endoscopy.2017; 85(6): 1117.     CrossRef
  • Contrast‐enhanced harmonic endoscopic ultrasonography for differential diagnosis of submucosal tumors of the upper gastrointestinal tract
    Ken Kamata, Mamoru Takenaka, Masayuki Kitano, Shunsuke Omoto, Takeshi Miyata, Kosuke Minaga, Kentaro Yamao, Hajime Imai, Toshiharu Sakurai, Tomohiro Watanabe, Naoshi Nishida, Takaaki Chikugo, Yasutaka Chiba, Haruhiko Imamoto, Takushi Yasuda, Andrea Lisott
    Journal of Gastroenterology and Hepatology.2017; 32(10): 1686.     CrossRef
  • How best to manage gastrointestinal stromal tumor
    Gandhi Lanke, Jeffrey H Lee
    World Journal of Clinical Oncology.2017; 8(2): 135.     CrossRef
  • EUS-guided 22-gauge fine needle biopsy for the diagnosis of gastric subepithelial tumors larger than 2 cm
    Jeong Hoon Lee, Charles J. Cho, Young Soo Park, Ji Yong Ahn, Do Hoon Kim, Hee Kyong Na, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
    Scandinavian Journal of Gastroenterology.2016; 51(4): 486.     CrossRef
  • Response:
    Moon Kyung Joo, Jong-Jae Park
    Gastrointestinal Endoscopy.2016; 83(4): 851.     CrossRef
  • EUS-guided fine needle biopsy sampling using a novel fork-tip needle: a case-control study
    Pujan Kandel, Ghassan Tranesh, Aziza Nassar, Russell Bingham, Massimo Raimondo, Timothy A. Woodward, Victoria Gomez, Michael B. Wallace
    Gastrointestinal Endoscopy.2016; 84(6): 1034.     CrossRef
  • Is Endoscopic Ultrasonography Adequate for the Diagnosis of Gastric Schwannomas?
    Eun Jeong Gong, Kee Don Choi
    Clinical Endoscopy.2016; 49(6): 498.     CrossRef
  • A Case of Gastrointestinal Stromal Tumor That Underwent Endoscopic Ultrasound-Guided Aspiration with a 25-Gauge Biopsy Needle
    Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
    Case Reports in Gastroenterology.2016; 10(1): 173.     CrossRef
  • Cytology of the gastrointestinal tract: opportunities to be tapped
    Darshana Jhala
    Diagnostic Histopathology.2015; 21(12): 462.     CrossRef
  • Which Needle Is Better for Diagnosing Subepithelial Lesions?
    Eun Young Kim
    Clinical Endoscopy.2015; 48(2): 91.     CrossRef
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  • 37 Web of Science
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Case Report
Primary Fallopian Tube Carcinoma Diagnosed with Endoscopic Ultrasound Elastography with Fine Needle Biopsy
Eui Bae Kim, Tae Hee Lee, Jeong Sig Kim, In Ho Choi
Clin Endosc 2014;47(5):464-468.   Published online September 30, 2014
DOI: https://doi.org/10.5946/ce.2014.47.5.464
AbstractAbstract PDFPubReaderePub

Primary fallopian tube carcinoma (PFTC) is a rare gynecological cancer that is very difficult to diagnose preoperatively. Here, we report the case of a 66-year-old female patient with PFTC that was diagnosed preoperatively on the basis of the characteristic features on endoscopic ultrasound (EUS) elastography and fine needle biopsy (FNB). EUS showed a sausage-shaped hypoechoic mass, 8 cm in size, with irregular margins and heterogeneous internal echoes extending to both adnexa. EUS elastography revealed that the mass had a blue color pattern, representing hard stiffness, and a heterogeneous green/red color pattern distributed outside the tumor, representing intermediate stiffness. Histopathologic analysis of the FNB and operative specimens confirmed the diagnosis of fallopian tube carcinoma. This is the first reported case of a combined EUS elastography and FNB of an adnexal mass leading to a preoperative diagnosis of fallopian tube carcinoma.

Citations

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  • The clinical impact of ultrasound contrast agents in EUS: a systematic review according to the levels of evidence
    Pietro Fusaroli, Bertrand Napoleon, Rodica Gincul, Christine Lefort, Laurent Palazzo, Maxime Palazzo, Masayuki Kitano, Kosuke Minaga, Giancarlo Caletti, Andrea Lisotti
    Gastrointestinal Endoscopy.2016; 84(4): 587.     CrossRef
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  • 66 Download
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