Skip Navigation
Skip to contents

Clin Endosc : Clinical Endoscopy

OPEN ACCESS

Search

Page Path
HOME > Search
2 "Feasibility studies"
Filter
Filter
Article category
Keywords
Publication year
Authors
Original Articles
Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study
Germana de Nucci, Maria Chiara Petrone, Nicola Imperatore, Edoardo Forti, Roberto Grassia, Silvia Giovanelli, Laura Ottaviani, Vincenzo Mirante, Giuseppe Sabatino, Carlo Fabbri, Mauro Manno, Paolo Giorgio Arcidiacono, Gianpiero Manes
Clin Endosc 2021;54(2):229-235.   Published online May 25, 2020
DOI: https://doi.org/10.5946/ce.2020.056
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the go-to method for obtaining samples from gastrointestinal tract and pancreatic lesions. When the transduodenal approach is utilized, the use of a more flexible needle, such as a nitinol 19-gauge (G) needle, has been recommended. The aim of this study was to evaluate the feasibility and accuracy of 19-G flexible aspiration needles in obtaining samples from solid lesions through a transduodenal approach.
Methods
This was a retrospective analysis of prospectively collected data from eight Italian endoscopy centers. Consecutive patients with solid lesions who underwent transduodenal EUS-FNA with a 19-G flexible needle were included.
Results
A total of 201 patients were enrolled. According to histology, EUS, radiology and 12 months of follow-up, 151 patients had malignant lesions and 50 patients had benign lesions. EUS-FNA was feasible in all cases. An adequate histologic sample was obtained in all except eight cases (96.1%). The sensitivity of EUS-FNA was 92.1% (95% confidence interval [CI], 86.8%–95.7%), and the specificity was 100% (95% CI, 90.5%–100%). The positive predictive value was 100% (95% CI, 93.4%–100%), and the negative predictive value was 74% (95% CI, 62.8%–82.7%). The diagnostic accuracy was 93.5% (95% CI, 89.2%–96.5%).
Conclusions
The transduodenal approach for obtaining samples from solid lesions using a 19-G flexible needle seems feasible and accurate.

Citations

Citations to this article as recorded by  
  • Comparation of 5 ml and 10 ml Negative Pressures with Wet-suction Techniques for EUS-FNA of Solid Lesions
    Yuchun Zhu, Yang Su, Peng Yang, Jiaojun Li, Tai Yu, Yi Wang, Xi Zhou, Ming Zhao, Xiaobin Sun, Jing Shan
    Journal of Clinical Gastroenterology.2025; 59(1): 97.     CrossRef
  • Comparing needle types and aspiration techniques in EUS-TA to optimize diagnostic efficacy and specimen quality in patients with pancreatic lesions
    Rumin Shang, Xiangming Han, Fangwei He, Lihua Huang, Cui Zeng, Kun Chen, Fei Lv, Xiangwu Ding
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Diagnostic Ability of Endoscopic Ultrasound-Guided Tissue Acquisition Using 19-Gauge Fine-Needle Biopsy Needle for Abdominal Lesions
    Kotaro Takeshita, Susumu Hijioka, Yoshikuni Nagashio, Yuta Maruki, Yuki Kawasaki, Kosuke Maehara, Yumi Murashima, Mao Okada, Go Ikeda, Natsumi Yamada, Tetsuro Takasaki, Daiki Agarie, Hidenobu Hara, Yuya Hagiwara, Kohei Okamoto, Daiki Yamashige, Akihiro Oh
    Diagnostics.2023; 13(3): 450.     CrossRef
  • Effect of wet-heparinized suction on the quality of mediastinal solid tumor specimens obtained by endoscopic ultrasound-guided fine-needle aspiration: a retrospective study from a single center
    Bo Xu, Qian Lu, Rong Fang, Xiaojuan Dai, Haiyan Xu, Xiangwu Ding, Huawei Gui
    BMC Gastroenterology.2023;[Epub]     CrossRef
  • Comparison of Endoscopic Ultrasound-Guided Fine Needle Aspiration with 19-Gauge and 22-Gauge Needles for Solid Pancreatic Lesions
    Changjuan Li, Jianwei Mi, Fulai Gao, Xinying Zhu, Miao Su, Xiaoli Xie, Dongqiang Zhao
    International Journal of General Medicine.2021; Volume 14: 10439.     CrossRef
  • 5,052 View
  • 115 Download
  • 8 Web of Science
  • 5 Crossref
Close layer
Peroral Endoscopic Myotomy for Treating Achalasia in an Animal Model: A Feasibility Study
Byoung Wook Bang, Young Chul Choi, Hyung Gil Kim, Kye Sook Kwon, Yong Woon Shin, Don Haeng Lee, Joon Mee Kim
Clin Endosc 2013;46(1):54-58.   Published online January 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.1.54
AbstractAbstract PDFPubReaderePub
Background/Aims

Laparoscopic Heller myotomy with antireflux procedure is considered to be a standard treatment for achalasia. Recently, peroral endoscopic myotomy (POEM) was developed and performed on patients with achalasia. However, there is no report on POEM use in South Korea. The aim of this study was to evaluate the technical feasibility of POEM in a porcine model.

Methods

POEM was performed on two mini pigs. We performed upper endoscopy under general anesthesia. A submucosal tunnel was created and the circular muscle layer was incised using several knives. The mucosal entry was closed using resolution clips. We performed a follow-up endoscopy and sacrificed the pigs 2 weeks after the POEM. The myotomy site was evaluated grossly and histologically.

Results

POEM was successfully performed on the two mini pigs. No injuries to any abdominal or mediastinal structures occurred. Two weeks after the POEM, the esophageal mucosa healed without any endoscopic evidence of complications. Necropsy revealed that the circular muscle layer was completely lost and replaced with fibrotic tissue.

Conclusions

We found that POEM is a technically feasible method which can be performed on an animal model. However, to ensure safe use on patients with achalasia, further studies on technical methods and long-term follow-up examinations are required.

Citations

Citations to this article as recorded by  
  • Pilot prospective study on formal training in per-oral endoscopic myotomy (POEM) during advanced endoscopy fellowship
    Salmaan Jawaid, Peter V. Draganov, Hiroyuki Aihara, Mouen A. Khashab, Dennis Yang
    Endoscopy International Open.2021; 09(12): E1890.     CrossRef
  • Miotomía endoscópica peroral, experiencia in vivo : imprescindible para desarrollo de la técnica en humanos
    A. Peñaloza-Ramírez, J. Suárez-Correa, J. Báez-Blanco, C. Sabogal-Gómez, H. Kuan-Casas, C. Sánchez-Pignalosa, P. Aponte-Ordóñez
    Revista de Gastroenterología de México.2018; 83(2): 86.     CrossRef
  • In vivo experience with peroral endoscopic myotomy: An essential activity for developing the technique in humans
    A. Peñaloza-Ramírez, J. Suárez-Correa, J. Báez-Blanco, C. Sabogal-Gómez, H. Kuan-Casas, C. Sánchez-Pignalosa, P. Aponte-Ordóñez
    Revista de Gastroenterología de México (English Edition).2018; 83(2): 86.     CrossRef
  • Factors predicting the technical difficulty of peroral endoscopic myotomy for achalasia
    Xiaowei Tang, Yutang Ren, Zhengjie Wei, Jieqiong Zhou, Zhiliang Deng, Zhenyu Chen, Bo Jiang, Wei Gong
    Surgical Endoscopy.2016; 30(9): 3774.     CrossRef
  • Peroral endoscopic myotomy for treatment of achalasia in children and adolescents
    Chenjie Li, Yuyong Tan, Xuehong Wang, Deliang Liu
    Journal of Pediatric Surgery.2015; 50(1): 201.     CrossRef
  • The Ideal Experimental Training Session for Minimally Invasive Endoluminal Techniques
    Sakai P
    Gastroenterology & Hepatology: Open Access.2015;[Epub]     CrossRef
  • International Digestive Endoscopy Network 2014: Turnpike to the Future
    Eun Young Kim, Kwang An Kwon, Il Ju Choi, Ji Kon Ryu, Ki Baik Hahm
    Clinical Endoscopy.2014; 47(5): 371.     CrossRef
  • Training for peroral endoscopic myotomy
    Daniel von Renteln, Melina C. Vassiliou, Thomas Rösch
    Techniques in Gastrointestinal Endoscopy.2013; 15(3): 153.     CrossRef
  • Peroral Endoscopic Myotomy for the Treatment of Achalasia: An Analysis
    Dennis Yang, Mihir S. Wagh
    Diagnostic and Therapeutic Endoscopy.2013; 2013: 1.     CrossRef
  • Peroral Endoscopic Myotomy in a Porcine Model: A Step to Achalasia Patients
    Su Jin Hong
    Clinical Endoscopy.2013; 46(1): 1.     CrossRef
  • 6,853 View
  • 67 Download
  • 10 Crossref
Close layer

Clin Endosc : Clinical Endoscopy Twitter Facebook
Close layer
TOP