Clinical Endoscopy

Skip Navigation: Skip to contents

OPEN ACCESS

mobile search button mobile menu button

Search

Page Path: HOME > Search

Original Article

Clinicopathological and endoscopic features of Helicobacter pylori infection-negative gastric cancer in Japan: a retrospective study: Kentaro Imamura, Kenshi Yao, Satoshi Nimura, Takao Kanemitsu, Masaki Miyaoka, Yoichiro Ono, Toshiharu Ueki, Hiroshi Tanabe; Clin Endosc 2024;57(4):486-494. Published online March 22, 2024; DOI: https://doi.org/10.5946/ce.2023.258

Graphical Abstract Abstract PDF PubReader ePub

Background
/Aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC.
Methods
This single-center retrospective study selected participants from patients with gastric cancer who were treated at the Fukuoka University Chikushi Hospital between January 2013 and December 2021. Only patients diagnosed with HPNGC were enrolled, and their clinicopathological and endoscopic features were analyzed in detail.
Results
The prevalence of HPNGC in the present study was 2.6% (54/2112). The types of HPNGC observed in each gastric region were as follows: advanced gastric cancer was observed in the cardia; gastric adenocarcinoma of fundic-gland differentiation, gastric adenocarcinoma of foveolar-type presenting with whitish elevation and raspberry-like foveolar-type gastric adenocarcinoma, gastric adenocarcinoma arising in polyposis, and gastric adenocarcinoma with autoimmune gastritis were observed in the fundic gland region ranging from the gastric fornix to the gastric body; signet-ring cell carcinoma was observed in the gastric-pyloric transition region ranging from the lower gastric body to the gastric angle; and well-differentiated tubular adenocarcinoma with low-grade atypia was observed in the antrum.
Conclusions
This study revealed that tumors from each gastric region exhibited distinct macroscopic and histological types in HPNGC.

Citations

Citations to this article as recorded by

Is your endoscopist qualified enough to detect Helicobacter pylori-naive status?
Sun-Young Lee
Clinical Endoscopy.2024; 57(4): 466. CrossRef

5,002 View
310 Download
1 Web of Science
1 Crossref

Review

E-learning system to improve the endoscopic diagnosis of early gastric cancer: Kenshi Yao, Takashi Yao, Noriya Uedo, Hisashi Doyama, Hideki Ishikawa, Satoshi Nimura, Yuichi Takahashi; Clin Endosc 2024;57(3):283-292. Published online August 3, 2023; DOI: https://doi.org/10.5946/ce.2023.087

Abstract PDF PubReader ePub

We developed three e-learning systems for endoscopists to acquire the necessary skills to improve the diagnosis of early gastric cancer (EGC) and demonstrated their usefulness using randomized controlled trials. The subjects of the three e-learning systems were “detection”, “characterization”, and “preoperative assessment”. The contents of each e-learning system included “technique”, “knowledge”, and “obtaining experience”. All e-learning systems proved useful for endoscopists to learn how to diagnose EGC. Lecture videos describing “the technique” and “the knowledge” can be beneficial. In addition, repeating 100 self-study cases allows learners to gain “experience” and improve their diagnostic skills further. Web-based e-learning systems have more advantages than other teaching methods because the number of participants is unlimited. Histopathological diagnosis is the gold standard for the diagnosis of gastric cancer. Therefore, we developed a comprehensive diagnostic algorithm to standardize the histopathological diagnosis of gastric cancer. Once we have successfully shown that this algorithm is helpful for the accurate histopathological diagnosis of cancer, we will complete a series of e-learning systems designed to assess EGC accurately.

Citations

Citations to this article as recorded by

Use of a short educational video to improve the accuracy of colorectal polyp morphology assessment: A multicenter randomized controlled study
Takahiro Utsumi, Takahiro Horimatsu, Yoshitaka Nishikawa, Akira Teramoto, Daizen Hirata, Mineo Iwatate, Shinwa Tanaka, Nobuaki Ikezawa, Masaya Esaki, Shozo Osera, Chikara Ebisutani, Hiroaki Saito, Nobukazu Agatsuma, Yukiko Hiramatasu, Yuki Nakanishi, Yasu
DEN Open.2025;[Epub] CrossRef
Pitfalls in Endoscopic Submucosal Dissection for Early Gastric Cancer with Papillary Adenocarcinoma
Gwang Ha Kim
Gut and Liver.2024; 18(3): 368. CrossRef
Comparing Raman Spectroscopy-Based Artificial Intelligence to High-Definition White Light Endoscopy for Endoscopic Diagnosis of Gastric Neoplasia: A Feasibility Proof-of-Concept Study
Tse Kiat Soong, Guo Wei Kim, Daryl Kai Ann Chia, Jimmy Bok Yan So, Jonathan Wei Jie Lee, Asim Shabbbir, Jeffrey Huey Yew Lum, Gwyneth Shook Ting Soon, Khek Yu Ho
Diagnostics.2024; 14(24): 2839. CrossRef

4,699 View
485 Download
3 Web of Science
3 Crossref

Case Report

Gastric cancer presenting with ramucirumab-related gastrocolic fistula successfully managed by colonic stenting: a case report: Hiroki Fukuya, Yoichiro Iboshi, Masafumi Wada, Yorinobu Sumida, Naohiko Harada, Makoto Nakamuta, Hiroyuki Fujii, Eikichi Ihara; Clin Endosc 2023;56(6):812-816. Published online May 11, 2023; DOI: https://doi.org/10.5946/ce.2022.117

Abstract PDF PubReader ePub

We report a rare case of gastric cancer presenting with a gastrocolic fistula during ramucirumab and paclitaxel combination therapy that was successfully managed with colonic stenting. A 75-year-old man was admitted to our hospital with the chief complaint of melena. Esophagogastroduodenoscopy revealed a large ulcerated tumor in the lower stomach, judged by laparoscopy as unresectable (sT4bN1M0). After four cycles of first-line chemotherapy with S-1 plus oxaliplatin, the patient showed disease progression, and second-line therapy with ramucirumab and paclitaxel was started. At the end of the third cycle, the patient had gastric antral stenosis, which necessitated the placement of a gastroduodenal stent. When the patient complained of diarrhea 10 days later, esophagogastroduodenoscopy revealed a fistula between the greater curvature of the stomach and the transverse colon. The fistula was covered by double colonic stenting, with a covered metal stent placed within an uncovered metal stent, after which leakage from the stomach to the colon stopped.

Citations

Citations to this article as recorded by

Ramucirumab

Reactions Weekly.2024; 1989(1): 189. CrossRef
Metastatic bladder cancer forming a sigmoidorectal fistula after enfortumab vedotin therapy: a case report
Shinji Tamada, Daiki Ikarashi, Naoki Yanagawa, Moe Toyoshima, Kenta Takahashi, Tomohiko Matsuura, Shigekatsu Maekawa, Renpei Kato, Mitsugu Kanehira, Ryo Takata, Wataru Obara
Frontiers in Oncology.2023;[Epub] CrossRef

2,976 View
160 Download
1 Web of Science
2 Crossref

Original Articles

The pattern of metachronous recurrence after endoscopic submucosal dissection for gastric adenocarcinoma and dysplasias: Sunah Suk, Yeon Joo Seo, Dae Young Cheung, Han Hee Lee, Jin Il Kim, Soo-Heon Park; Clin Endosc 2023;56(4):470-478. Published online April 18, 2023; DOI: https://doi.org/10.5946/ce.2022.259

Graphical Abstract Abstract PDF PubReader ePub

Background
/Aims: Metachronous recurrence incidences and risk factors following endoscopic submucosal dissection (ESD) for gastric adenocarcinoma and dysplasias were investigated.
Methods
Retrospective review of electronic medical records of patients who underwent gastric ESD at The Catholic University of Korea, Yeouido St. Mary’s Hospital.
Results
A total of 190 subjects were enrolled for analysis during the study period. The mean age was 64.4 years-old and the male sex occupied 73.7%. The mean observation period following ESD was 3.45 years. The annual incidence rate of metachronous gastric neoplasms (MGN) was about 3.96%. The annual incidence rate was 5.36% for the low-grade dysplasia group, 6.47% for the high-grade dysplasia group, and 2.74% for the EGC group. MGN was more frequent in the dysplasia group than in the EGC group (p<0.05). For those with MGN development, the mean time interval from ESD to MGN was 4.1 (±1.8) years. By using the Kaplan–Meier model, the estimated mean MGN free survival time was 9.97 years (95% confidence interval, 8.53–11.40) The histological types of MGN were not related to the primary histology types.
Conclusions
MGN following ESD developed in 3.96% annually and MGN was more frequent in the dysplasia group. The histological types of MGN did not correlate with those of primary neoplasm.

Citations

Citations to this article as recorded by

Research Progress in ESD Treatment of Early Gastric Cancer
亭贺
Advances in Clinical Medicine.2024; 14(02): 4201. CrossRef
Optimal Surveillance of Metachronous Gastric Lesion after Endoscopic Resection of Early Gastric Cancer
Dong Chan Joo, Gwang Ha Kim
Gut and Liver.2024; 18(5): 781. CrossRef
Risk Assessment of Metachronous Gastric Neoplasm after Endoscopic Resection for Early Gastric Cancer According to Age at Helicobacter pylori Eradication
Seunghan Lee, Soo-Jeong Cho, Hyunsoo Chung, Bokyung Kim, Mi Jin Oh, Yun Suk Na, Jun Hee Lee, Jiyoon Kim, Sang Gyun Kim
Gut and Liver.2024; 18(6): 992. CrossRef

2,639 View
94 Download
2 Web of Science
3 Crossref

Exploring quality indicators for the detection of Helicobacter pylori-naïve gastric cancer: a cross-sectional nationwide survey: Fumiaki Ishibashi, Toshiaki Hirasawa, Hiroya Ueyama, Yohei Minato, Sho Suzuki; Clin Endosc 2023;56(4):460-469. Published online April 4, 2023; DOI: https://doi.org/10.5946/ce.2022.167

Graphical Abstract Abstract PDF Supplementary Material PubReader ePub

Background
/Aims: Diagnosis of Helicobacter pylori-naïve gastric cancer (HPNGC) is becoming increasingly important. This study aimed to explore the quality indicators for HPNGC detection.
Methods
We conducted a cross-sectional, nationwide, web-based survey of gastrointestinal endoscopists in Japan. In addition to questions about the number of HPNGC cases detected in a year and basic information, the questionnaire also consisted of 28 questions: (1) 18 about HPNGC awareness, (2) six about diagnostic proactiveness, and (3) four about interest in HPNGC.
Results
Valid responses were obtained from 712 endoscopists. The Japan Gastroenterological Endoscopy Society-certified endoscopists had a significantly higher HPNGC detection rate than the nonspecialists (0.42% vs. 0.32%, respectively; p=0.008). The results of the multiple regression analysis showed that Japan Gastroenterological Endoscopy Society certification and high awareness and interest scores were independent predictors of the HPNGC detection rate (p=0.012, p<0.001, p=0.024, respectively). Principal component analysis showed that the endoscopists who attended conferences for collecting information on HPNGC had a higher level of awareness.
Conclusions
To improve the detection of HPNGC, it is necessary to increase the awareness of the disease. It is hoped that relevant societies will play an important role in endoscopists’ education.

Citations

Citations to this article as recorded by

Visibility evaluation of gastric epithelial neoplasm of fundic gland mucosa lineage using texture and color enhancement imaging
Hisanori Utsunomiya, Hiroya Ueyama, Tsutomu Takeda, Shunsuke Nakamura, Yasuko Uemura, Tomoyo Iwano, Momoko Yamamoto, Ryota Uchida, Daiki Abe, Shotaro Oki, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kumiko Ueda, Mariko Hojo, Shuko Nojiri, Takashi Yao,
DEN Open.2025;[Epub] CrossRef
Prevalence of Gastric Epithelial Tumors in Helicobacter pylori-uninfected Individuals Undergoing a Medical Checkup
Eiko Okimoto, Kyoichi Adachi, Yuri Ebisutani, Norihisa Ishimura, Shunji Ishihara
Internal Medicine.2024; 63(16): 2251. CrossRef
A mathematical simulation model to determine the optimal endoscopic screening strategy for detection of H. pylori-naïve gastric neoplasms
Fumiaki Ishibashi, Kosuke Okusa, Yoshitaka Tokai, Toshiaki Hirasawa, Tomohiro Kawakami, Kentaro Mochida, Yuka Yanai, Chizu Yokoi, Yuko Hayashi, Shun-ichiro Ozawa, Koji Uraushihara, Yohei Minato, Hiroyuki Nakanishi, Hiroya Ueyama, Mikinori Kataoka, Yuzo To
Gastric Cancer.2024; 27(5): 1078. CrossRef
Improving the quality of the esophagogastroduodenoscopy in Helicobacter pylori-naïve gastric cancer
Jae Myung Park
Clinical Endoscopy.2023; 56(4): 453. CrossRef

3,628 View
145 Download
4 Web of Science
4 Crossref

Case Report

Gastric wall abscess after endoscopic submucosal dissection: Seung Jung Yu, Sang Heon Lee, Jun Sik Yoon, Hong Sub Lee, Sam Ryong Jee; Clin Endosc 2023;56(1):114-118. Published online January 3, 2022; DOI: https://doi.org/10.5946/ce.2021.203

Abstract PDF PubReader ePub

Gastric wall abscess, a localized form of phlegmonous gastritis, is a rare complication of endoscopic resection. We report the first case of gastric wall abscess developing after endoscopic submucosal dissection in Korea. A 72-year-old woman visited our clinic to receive treatment for gastric adenoma. The patient successfully underwent endoscopic submucosal dissection with no complications. The final diagnosis was well-differentiated tubular adenocarcinoma. We performed follow-up endoscopy 10 weeks later and found a large subepithelial lesion on the posterior wall of the gastric antrum. Abdominal computed tomography revealed hypodense wall thickening and a 5 cm heterogenous multilobular mass in the submucosal layer of the gastric antrum. Submucosal invasion with mucin-producing adenocarcinomas could therefore not be excluded. The patient agreed to undergo additional gastrectomy due to the possibility of a highly malignant lesion. The final diagnosis was acute suppurative inflammation with the formation of multiple abscesses in the mural layers and omentum. The patient was discharged with no complications.

Citations

Citations to this article as recorded by

Phlegmonous gastritis after biloma drainage: A case report and review of the literature
Kai-Chun Yang, Hsin-Yu Kuo, Jui-Wen Kang
World Journal of Clinical Cases.2022; 10(33): 12430. CrossRef

5,186 View
291 Download
3 Web of Science
1 Crossref

Original Articles

Efficacy and Safety of Endoscopic Submucosal Dissection for Superficial Gastric Neoplasms: A Latin American Cohort Study: Fernando Palacios-Salas, Harold Benites-Goñi, Luis Marin-Calderón, Paulo Bardalez-Cruz, Jorge Vásquez-Quiroga, Edgar Alva-Alva, Bryan Medina-Morales, Jairo Asencios-Cusihuallpa; Clin Endosc 2022;55(2):248-255. Published online November 12, 2021; DOI: https://doi.org/10.5946/ce.2021.192

Abstract PDF PubReader ePub

Background
/Aims: Endoscopic submucosal dissection (ESD) is the preferred technique for treating early gastric cancer (EGC). However, very few studies have been conducted in South America. This study aimed to assess the efficacy and safety of ESD for EGC.
Methods
We analyzed data from a prospective cohort from 2013 to 2020. A total of 152 superficial gastric neoplasms that fulfilled the absolute or expanded criteria for ESD were included. Outcomes were en bloc, R0, and curative resection rates, incidence of adverse events, and length of procedure.
Results
The age of the enrolled patients was 68.4±11.3 years. The number of included patients based on the absolute and expanded indications was 150 and 2, respectively. En bloc, R0, and curative resections were achieved in 98.0%, 96.1%, and 89.5% of the cases, respectively. Bleeding and perforation were reported in 5.9% and 6.6% of the cases, respectively. Histopathological examination revealed lowgrade dysplasia, high-grade dysplasia, well-differentiated adenocarcinoma, and poorly differentiated adenocarcinoma in 13, 20, 117, and 2 cases, respectively.
Conclusions
Our study shows that ESD performed by properly trained endoscopists in reference centers is safe and effective, with comparable therapeutic outcomes to those reported in the Eastern series.

Citations

Citations to this article as recorded by

Outcomes and validity of risk stratification tools for endoscopic submucosal dissection of early gastric cancer in Western Australia
Ciaran Judge, Abir Halder, Puraskar Pateria, Tzeng Khor, Niroshan Muwanwella, Marcus Chin, Krish Ragunath
JGH Open.2024;[Epub] CrossRef
Disección submucosa endoscópica en cáncer gástrico temprano indiferenciado: evaluación de los primeros casos y análisis de su aplicación como indicación absoluta en Perú
Fernando Palacios-Salas, Luis Marin-Calderón, Juan Chirinos-Vega, Paulo Bardalez-Cruz, Patricia Valera-Luján, Dacio Cabrera-Hinojosa, Harold Benites-Goñi
Revista de Gastroenterología del Perú.2024; 44(4): 333. CrossRef
Short-Term and Long-Term Outcomes of Liver Cirrhosis in Gastric Neoplasm Patients Undergoing Endoscopic Submucosal Dissection
Xu-Rui Liu, Lian-Shuo Li, Fei Liu, Zi-Wei Li, Xiao-Yu Liu, Wei Zhang, Dong Peng
Journal of Laparoendoscopic & Advanced Surgical Techniques.2023; 33(7): 640. CrossRef
Endoscopic submucosal dissection for early gastric cancer: It is time to consider the quality of its outcomes
Gwang Ha Kim
World Journal of Gastroenterology.2023; 29(43): 5800. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef

5,104 View
244 Download
6 Web of Science
6 Crossref

Clinical Impact of Different Reconstruction Methods on Remnant Gastric Cancer at the Anastomotic Site after Distal Gastrectomy: Kei Matsumoto, Shinwa Tanaka, Takashi Toyonaga, Nobuaki Ikezawa, Mari Nishio, Masanao Uraoka, Tomoatsu Yoshihara, Hiroya Sakaguchi, Hirofumi Abe, Tetsuya Yoshizaki, Madoka Takao, Toshitatsu Takao, Yoshinori Morita, Hiroshi Yokozaki, Yuzo Kodama; Clin Endosc 2022;55(1):86-94. Published online August 13, 2021; DOI: https://doi.org/10.5946/ce.2021.084

Abstract PDF Supplementary Material PubReader ePub: Background
/Aims: The anastomotic site after distal gastrectomy is the area most affected by duodenogastric reflux. Different reconstruction methods may affect the lesion characteristics and treatment outcomes of remnant gastric cancers at the anastomotic site. We retrospectively investigated the clinicopathologic and endoscopic submucosal dissection outcomes of remnant gastric cancers at the anastomotic site.
Methods
We recruited 34 consecutive patients who underwent endoscopic submucosal dissection for remnant gastric cancer at the anastomotic site after distal gastrectomy. Clinicopathology and treatment outcomes were compared between the Billroth II and non-Billroth II groups.
Results
The tumor size in the Billroth II group was significantly larger than that in the non-Billroth II group (22 vs. 19 mm; p=0.048). More severe gastritis was detected endoscopically in the Billroth II group (2 vs. 1.33; p=0.0075). Moreover, operation time was longer (238 vs. 121 min; p=0.004) and the frequency of bleeding episodes was higher (7.5 vs. 3.1; p=0.014) in the Billroth II group.
Conclusions
Compared to remnant gastric cancers in non-Billroth II patients, those in the Billroth II group had larger lesions with a background of severe remnant gastritis. Endoscopic submucosal dissection for remnant gastric cancers in Billroth II patients involved longer operative times and more frequent bleeding episodes than that in patients without Billroth II.

5,037 View
165 Download

Clinical Outcomes and Adverse Events of Gastric Endoscopic Submucosal Dissection of the Mid to Upper Stomach under General Anesthesia and Monitored Anesthetic Care: Jong-In Chang, Tae Jun Kim, Na Young Hwang, Insuk Sohn, Yang Won Min, Hyuk Lee, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J Kim; Clin Endosc 2022;55(1):77-85. Published online July 5, 2021; DOI: https://doi.org/10.5946/ce.2021.002

Abstract PDF Supplementary Material PubReader ePub

Background
/Aims: Endoscopic submucosal dissection (ESD) of gastric tumors in the mid-to-upper stomach is a technically challenging procedure. This study compared the therapeutic outcomes and adverse events of ESD of tumors in the mid-to-upper stomach performed under general anesthesia (GA) or monitored anesthesia care (MAC).
Methods
Between 2012 and 2018, 674 patients underwent ESD for gastric tumors in the midbody, high body, fundus, or cardia (100 patients received GA; 574 received MAC). The outcomes of the propensity score (PS)-matched (1:1) patients receiving either GA or MAC were analyzed.
Results
The PS matching identified 94 patients who received GA and 94 patients who received MAC. Both groups showed high rates of en bloc resection (GA, 95.7%; MAC, 97.9%; p=0.68) and complete resection (GA, 81.9%; MAC, 84.0%; p=0.14). There were no significant differences between the rates of adverse events (GA, 16.0%; MAC, 8.5%; p=0.18) in the anesthetic groups. Logistic regression analysis indicated that the method of anesthesia did not affect the rates of complete resection or adverse events.
Conclusions
ESD of tumors in the mid-to-upper stomach at our high-volume center had good outcomes, regardless of the method of anesthesia. Our results demonstrate no differences between the efficacies and safety of ESD performed under MAC and GA.

Citations

Citations to this article as recorded by

Efficacy, safety, and impact on procedural outcomes of local anesthesia in endoscopic submucosal dissection: a systematic review and meta-analysis
Hazem Abosheaishaa, Abdelmalek Abdelghany, Abdallfatah Abdallfatah, Doha Mohamed, Ammar Ayman Bahbah, Islam Mohamed, Khaled Elfert, Ahmed E. Salem, Azizullah Beran, Ahmad Madkour, Mohammad Al-Haddad
Baylor University Medical Center Proceedings.2024; 37(6): 963. CrossRef
General Anesthesia and Endoscopic Upper Gastrointestinal Tumor Resection
Seung Hyun Kim
Journal of Digestive Cancer Research.2023; 11(3): 125. CrossRef
Comparing general anaesthesia versus sedation for endoscopic submucosal dissection: results from a systematic review and meta-analysis
Choy-May Leung, Rex Wan-Hin Hui
Anaesthesiology Intensive Therapy.2023; 55(1): 9. CrossRef
Is General Anesthesia Needed in Endoscopic Submucosal Dissection for Lesions Located in the Mid to Upper Stomach?
Prasit Mahawongkajit, Jirawat Swangsri
Clinical Endoscopy.2022; 55(1): 43. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef
Paneth Cell Carcinoma of the Stomach
Jun Wan Kim, Gwang Ha Kim, Kyung Bin Kim
The Korean Journal of Gastroenterology.2022; 80(1): 34. CrossRef
Comparing Different Anesthesia Methods on Anesthetic Effect and Postoperative Pain in Patients with Early Gastric Cancer during Endoscopic Submucosal Dissection
Jie Zhang, Yanlei Chen, Zhiwu Liu, Zhihao Pan, Jinghua Pan
Journal of Oncology.2022; 2022: 1. CrossRef

4,576 View
193 Download
5 Web of Science
7 Crossref

Histological Architecture of Gastric Epithelial Neoplasias That Showed Absent Microsurface Patterns, Visualized by Magnifying Endoscopy with Narrow-Band Imaging: Kenta Chuman, Kenshi Yao, Takao Kanemitsu, Takashi Nagahama, Masaki Miyaoka, Haruhiko Takahashi, Kentaro Imamura, Rino Hasegawa, Toshiharu Ueki, Hiroshi Tanabe, Seiji Haraoka, Akinori Iwashita; Clin Endosc 2021;54(2):222-228. Published online November 24, 2020; DOI: https://doi.org/10.5946/ce.2020.090

Abstract PDF PubReader ePub

Background
/Aims: The objective of this study was to elucidate the histological structure of the absent microsurface patterns (MSPs) that were visualized by magnifying endoscopy with narrow-band imaging (M-NBI).
Methods
The study included consecutive gastric epithelial neoplasias for which M-NBI findings and histological findings could be compared on a one-to-one basis. The lesions were classified as absent MSPs and present MSPs based on the findings obtained using M-NBI. Of the histopathological findings for each lesion that corresponded to M-NBI findings, crypt opening densities, crypt lengths, crypt opening diameters, intercrypt distances, and crypt angles were measured and compared.
Results
Thirty-six lesions were included in the analysis; of these, 17 lesions exhibited absent MSP and 19 lesions exhibited present MSP. Comparing the histological measurements for absent MSPs vs. present MSPs, median crypt opening density was 0.9 crypt openings/mm vs. 4.8 crypt openings/mm (p<0.001), respectively. The median crypt length, median crypt opening diameter, median intercrypt distance, and median crypt angle were 80.0 μm vs. 160 μm (p<0.001), 40.0 μm vs. 44.2 μm (p=0.09), 572.5 μm vs. 166.7 μm (p<0.001), and 21.6 degrees vs. 15.5 degrees (p<0.001), respectively.
Conclusions
Histological findings showed that lesions exhibiting absent MSPs had lower crypt opening density, shorter crypt length, greater intercrypt distance, and larger crypt angle.

Citations

Citations to this article as recorded by

Correlation between White Globe Appearance and Clinicopathologic Characteristics in Early Gastric Cancer
Dae Jin Jung, Gwang Ha Kim, Kyungbin Kim, Hye Kyung Jeon, Dong Chan Joo, Moon Won Lee, Bong Eun Lee
Gut and Liver.2025; 19(1): 50. CrossRef
The staining results of early gastric cancer by indigo carmine chromoendoscopy associated with histological structure: a retrospective study
Xiaosa Jiang, Lingzhi Qin, Yujie Hao, Qian Yang, Yueqin Zheng, Baicang Zou, Lei Dong, Na Liu, Jinhai Wang, Bin Qin
BMC Cancer.2024;[Epub] CrossRef
Magnifying Endoscopy with Narrow-Band Imaging for Duodenal Neuroendocrine Tumors
Gwang Ha Kim, Kiyoun Yi, Dong Chan Joo, Moon Won Lee, Hye Kyung Jeon, Bong Eun Lee
Journal of Clinical Medicine.2023; 12(9): 3106. CrossRef

5,070 View
155 Download
3 Web of Science
3 Crossref

Focused Review Series: Application of Artificial Intelligence in GI Endoscopy

Lesion-Based Convolutional Neural Network in Diagnosis of Early Gastric Cancer: Hong Jin Yoon, Jie-Hyun Kim; Clin Endosc 2020;53(2):127-131. Published online March 30, 2020; DOI: https://doi.org/10.5946/ce.2020.046

Abstract PDF PubReader ePub

Diagnosis and evaluation of early gastric cancer (EGC) using endoscopic images is significantly important; however, it has some limitations. In several studies, the application of convolutional neural network (CNN) greatly enhanced the effectiveness of endoscopy. To maximize clinical usefulness, it is important to determine the optimal method of applying CNN for each organ and disease. Lesion�-based CNN is a type of deep learning model designed to learn the entire lesion from endoscopic images. This review describes the application of lesion-based CNN technology in diagnosis of EGC.

Citations

Citations to this article as recorded by

Past, Present, and Future
Sarah Enslin, Vivek Kaul
Gastrointestinal Endoscopy Clinics of North America.2025; 35(2): 265. CrossRef
Revolutionizing diagnosis of pulmonary Mycobacterium tuberculosis based on CT: a systematic review of imaging analysis through deep learning
Fei Zhang, Hui Han, Minglin Li, Tian Tian, Guilei Zhang, Zhenrong Yang, Feng Guo, Maomao Li, Yuting Wang, Jiahe Wang, Ying Liu
Frontiers in Microbiology.2025;[Epub] CrossRef
A reconstruction and convolution operations enabled variant vision transformer with gastroscopic images for automatic locating of polyps in Internet of Medical Things
Zhe Qin, Yaqiong Zhang, Jian Li, Deming Li, Yanqing Mo, Liyang Wang, Peiyu Qian, Li Feng
Information Fusion.2024; 101: 102007. CrossRef
Diagnosis of gastric cancer in role of endoscopic imaging techniques in artificial intelligence and machine learning applications: An overview
Pooja K., Kishore Kanna R., G. Li, U. Subramaniam, M. Sekar
E3S Web of Conferences.2024; 491: 03016. CrossRef
Using RNN Artificial Neural Network to Predict the Occurrence of Gastric Cancer in the Future of the World
Seyed Masoud Ghoreishi Mokri, Newsha Valadbeygi, Khafaji Mohammed Balyasimovich
International Journal of Innovative Science and Research Technology (IJISRT).2024; : 1865. CrossRef
Advanced Detection of Chronic Atrophic Gastritis Using High-Resolution Endoscopy and Semantic Web
Junyi Zhao, Yaxin Gao, Jinbao Li
International Journal on Semantic Web and Information Systems.2024; 20(1): 1. CrossRef
A review on recent advances of AI-integrated microfluidics for analytical and bioanalytical applications
Elham Asadian, Farshad Bahramian, Saeed Siavashy, Sara Movahedi, Rüstem Keçili, Chaudhery Mustansar Hussain, Fatemeh Ghorbani-Bidkorpeh
TrAC Trends in Analytical Chemistry.2024; 181: 118004. CrossRef
Validation of Artificial Intelligence Computer-Aided Detection on Gastric Neoplasm in Upper Gastrointestinal Endoscopy
Hannah Lee, Jun-Won Chung, Sung-Cheol Yun, Sung Woo Jung, Yeong Jun Yoon, Ji Hee Kim, Boram Cha, Mohd Azzam Kayasseh, Kyoung Oh Kim
Diagnostics.2024; 14(23): 2706. CrossRef
A review on deep learning applications in highly multiplexed tissue imaging data analysis
Mohammed Zidane, Ahmad Makky, Matthias Bruhns, Alexander Rochwarger, Sepideh Babaei, Manfred Claassen, Christian M. Schürch
Frontiers in Bioinformatics.2023;[Epub] CrossRef
Construction and Multicenter Diagnostic Verification of Intelligent Recognition System for Endoscopic Images From Early Gastric Cancer Based on YOLO-V3 Algorithm
Zhendong Yao, Tao Jin, Boneng Mao, Bo Lu, Yefei Zhang, Sisi Li, Weichang Chen
Frontiers in Oncology.2022;[Epub] CrossRef
An Investigational Approach for the Prediction of Gastric Cancer Using Artificial Intelligence Techniques: A Systematic Review
Priya Bhardwaj, Gaurav Bhandari, Yogesh Kumar, Surbhi Gupta
Archives of Computational Methods in Engineering.2022; 29(6): 4379. CrossRef
Toward Automatic Detection of Gastric Lesion for Upper Gastrointestinal Endoscopy with Neural Network
Sai Wang, Qi He, Ping Zhang, Xin Chen, Siyang Zuo
Journal of Medical Robotics Research.2022;[Epub] CrossRef
Manta Ray Foraging Optimization Transfer Learning-Based Gastric Cancer Diagnosis and Classification on Endoscopic Images
Fadwa Alrowais, Saud S. Alotaibi, Radwa Marzouk, Ahmed S. Salama, Mohammed Rizwanullah, Abu Sarwar Zamani, Amgad Atta Abdelmageed, Mohamed I. Eldesouki
Cancers.2022; 14(22): 5661. CrossRef
Improvement for Diagnosis of Gastric Cancer from Endoscopic Images using Machine Learning
Maryam Kausar Khan, Muhammad Siddique, Naeem Aslam, Muntazir Hussain Khan, Sara Mukhtar, Bushra Syed
VFAST Transactions on Software Engineering.2022; 10(3): 10. CrossRef
Differential diagnosis for esophageal protruded lesions using a deep convolution neural network in endoscopic images
Min Zhang, Chang Zhu, Yun Wang, Zihao Kong, Yifei Hua, Weifeng Zhang, Xinmin Si, Bixing Ye, Xiaobing Xu, Lurong Li, Ding Heng, Baiyun Liu, Song Tian, Jiangfen Wu, Yini Dang, Guoxin Zhang
Gastrointestinal Endoscopy.2021; 93(6): 1261. CrossRef
Videomics: bringing deep learning to diagnostic endoscopy
Alberto Paderno, F. Christopher Holsinger, Cesare Piazza
Current Opinion in Otolaryngology & Head & Neck Surgery.2021; 29(2): 143. CrossRef
A combined microfluidic deep learning approach for lung cancer cell high throughput screening toward automatic cancer screening applications
Hadi Hashemzadeh, Seyedehsamaneh Shojaeilangari, Abdollah Allahverdi, Mario Rothbauer, Peter Ertl, Hossein Naderi-Manesh
Scientific Reports.2021;[Epub] CrossRef
Application of Artificial Intelligence in the Detection and Characterization of Colorectal Neoplasm
Kyeong Ok Kim, Eun Young Kim
Gut and Liver.2021; 15(3): 346. CrossRef
The Application and Development of Deep Learning in Radiotherapy: A Systematic Review
Danju Huang, Han Bai, Li Wang, Yu Hou, Lan Li, Yaoxiong Xia, Zhirui Yan, Wenrui Chen, Li Chang, Wenhui Li
Technology in Cancer Research & Treatment.2021;[Epub] CrossRef
Usefulness of artificial intelligence in gastric neoplasms
Ji Hyun Kim, Seung-Joo Nam, Sung Chul Park
World Journal of Gastroenterology.2021; 27(24): 3543. CrossRef
Systems Biology of Gastric Cancer: Perspectives on the Omics-Based Diagnosis and Treatment
Xiao-Jing Shi, Yongjun Wei, Boyang Ji
Frontiers in Molecular Biosciences.2020;[Epub] CrossRef

6,480 View
170 Download
22 Web of Science
21 Crossref

Review

Clinical Practice Guideline for Endoscopic Resection of Early Gastrointestinal Cancer: Chan Hyuk Park, Dong-Hoon Yang, Jong Wook Kim, Jie-Hyun Kim, Ji Hyun Kim, Yang Won Min, Si Hyung Lee, Jung Ho Bae, Hyunsoo Chung, Kee Don Choi, Jun Chul Park, Hyuk Lee, Min-Seob Kwak, Bun Kim, Hyun Jung Lee, Hye Seung Lee, Miyoung Choi, Dong-Ah Park, Jong Yeul Lee, Jeong-Sik Byeon, Chan Guk Park, Joo Young Cho, Soo Teik Lee, Hoon Jai Chun; Clin Endosc 2020;53(2):142-166. Published online March 30, 2020; DOI: https://doi.org/10.5946/ce.2020.032

Abstract PDF Supplementary Material PubReader ePub

Although surgery was the standard treatment for early gastrointestinal cancers, endoscopic resection is now a standard treatment for early gastrointestinal cancers without regional lymph node metastasis. High-definition white light endoscopy, chromoendoscopy, and image-enhanced endoscopy such as narrow band imaging are performed to assess the edge and depth of early gastrointestinal cancers for delineation of resection boundaries and prediction of the possibility of lymph node metastasis before the decision of endoscopic resection. Endoscopic mucosal resection and/or endoscopic submucosal dissection can be performed to remove early gastrointestinal cancers completely by en bloc fashion. Histopathological evaluation should be carefully made to investigate the presence of risk factors for lymph node metastasis such as depth of cancer invasion and lymphovascular invasion. Additional treatment such as radical surgery with regional lymphadenectomy should be considered if the endoscopically resected specimen shows risk factors for lymph node metastasis. This is the first Korean clinical practice guideline for endoscopic resection of early gastrointestinal cancer. This guideline was developed by using mainly de novo methods and encompasses endoscopic management of superficial esophageal squamous cell carcinoma, early gastric cancer, and early colorectal cancer. This guideline will be revised as new data on early gastrointestinal cancer are collected.

Citations

Citations to this article as recorded by

Influence factors of clinical effects on patients with early gastric cancer: A retrospective study
Yong-Hua Zhang, Chao Ma, Xiao-Mei Huang, Yang Liu
World Journal of Gastrointestinal Surgery.2025;[Epub] CrossRef
Management Strategy of Non-curative ESD in Gastric Cancer: Curative Criteria, and the Critical Building Block for Determining Beyond It
Hyuk Lee
Journal of Gastric Cancer.2025; 25(1): 210. CrossRef
Risk stratification scores for lymph node metastases in T1 colorectal cancer—A systematic review
Rakesh Quinn, Giuleta Jamsari, Ewan MacDermid
Colorectal Disease.2025;[Epub] CrossRef
Risk Factors for Perforation in Endoscopic Treatment for Early Colorectal Cancer: A Nationwide ENTER-K Study
Ik Hyun Jo, Hyun Gun Kim, Young-Seok Cho, Hyun Jung Lee, Eun Ran Kim, Yoo Jin Lee, Sung Wook Hwang, Kyeong-Ok Kim, Jun Lee, Hyuk Soon Choi, Yunho Jung, Chang Mo Moon
Gut and Liver.2025; 19(1): 95. CrossRef
Measures to prevent esophageal stenosis are necessary after endoscopic submucosal dissection for early esophageal cancer lesions with a circumferential ratio of 75%–99%: a retrospective case analysis
Yong Gao, Jiao Zhu, Jianjun Li, Xue Peng, Xubiao Nie, Haiyan Zhao, Lifu Sheng, Chaoqiang Fan, Jianying Bai
Postgraduate Medical Journal.2025;[Epub] CrossRef
The Pilot Study on Detecting Perforation with Abdominal Ultrasound During Gastric Endoscopic Submucosal Dissection
Ji Eun Kim, Jeayoun Kim, Tae Se Kim, Yang Won Min, Hyuk Lee, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J. Kim
Diagnostics.2025; 15(3): 335. CrossRef
Stratifying Risk of Lymph Node Metastasis After Non-Curative Endoscopic Submucosal Dissection of Early Gastric Cancer: Comparison of the eCura System and Elderly Criteria
Tae-woo Kim, Hyo-Joon Yang, Giho Lee, Soo-Kyung Park, Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn
Journal of Gastric Cancer.2025; 25(2): 370. CrossRef
Image-enhanced endoscopy in upper gastrointestinal disease: focusing on texture and color enhancement imaging and red dichromatic imaging
Jae Yong Park
Clinical Endoscopy.2025; 58(2): 163. CrossRef
Tumor–lymph cross-plane projection reveals spatial relationship features: a ResNet-CBAM model for prognostic prediction in esophageal cancer
Jiayang Xu, Chen Huang, Qianshun Chen, Jieyang Wang, Yuyu Lin, Wei Tang, Wei Shen, Xunyu Xu
Frontiers in Oncology.2025;[Epub] CrossRef
Helicobacter pylori Treatment and Gastric Cancer Risk After Endoscopic Resection of Dysplasia: A Nationwide Cohort Study
Hae Won Yoo, Su Jin Hong, Shin Hee Kim
Gastroenterology.2024; 166(2): 313. CrossRef
A Modified eCura System to Stratify the Risk of Lymph Node Metastasis in Undifferentiated-Type Early Gastric Cancer After Endoscopic Resection
Hyo-Joon Yang, Hyuk Lee, Tae Jun Kim, Da Hyun Jung, Kee Don Choi, Ji Yong Ahn, Wan Sik Lee, Seong Woo Jeon, Jie-Hyun Kim, Gwang Ha Kim, Jae Myung Park, Sang Gyun Kim, Woon Geon Shin, Young-Il Kim, Il Ju Choi
Journal of Gastric Cancer.2024; 24(2): 172. CrossRef
Management after non-curative endoscopic resection of T1 rectal cancer
Hao Dang, Daan A. Verhoeven, Jurjen J. Boonstra, Monique E. van Leerdam
Best Practice & Research Clinical Gastroenterology.2024; 68: 101895. CrossRef
Tumor size discrepancy between endoscopic and pathological evaluations in colorectal endoscopic submucosal dissection
Takeshi Onda, Osamu Goto, Toshiaki Otsuka, Yoshiaki Hayasaka, Shun Nakagome, Tsugumi Habu, Yumiko Ishikawa, Kumiko Kirita, Eriko Koizumi, Hiroto Noda, Kazutoshi Higuchi, Jun Omori, Naohiko Akimoto, Katsuhiko Iwakiri
World Journal of Gastrointestinal Endoscopy.2024; 16(3): 136. CrossRef
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
Hong Tao Lin, Ahmed Abdelbaki, Somashekar G Krishna
World Journal of Gastroenterology.2024; 30(10): 1291. CrossRef
A new clinical model for predicting lymph node metastasis in T1 colorectal cancer
Kai Wang, Hui He, Yanyun Lin, Yanhong Zhang, Junguo Chen, Jiancong Hu, Xiaosheng He
International Journal of Colorectal Disease.2024;[Epub] CrossRef
The role of endoluminal surgery in a colorectal surgical practice. A global view
Ilker Ozgur, Fevzi Cengiz
Seminars in Colon and Rectal Surgery.2024; 35(2): 101023. CrossRef
Enhanced multi-class pathology lesion detection in gastric neoplasms using deep learning-based approach and validation
Byeong Soo Kim, Bokyung Kim, Minwoo Cho, Hyunsoo Chung, Ji Kon Ryu, Sungwan Kim
Scientific Reports.2024;[Epub] CrossRef
Innovations in dedicated PET instrumentation: from the operating room to specimen imaging
Hossein Arabi, Abdollah Saberi Manesh, Habib Zaidi
Physics in Medicine & Biology.2024; 69(11): 11TR03. CrossRef
Rare primary colonic T cell lymphoma with curative resection by endoscopic submucosal dissection: A case report
Yu-Hui Sun, Shuang-Shuang Lu, Ying Fang, Zhe Xiong, Qiu-Yue Sun, Jin Huang
World Journal of Clinical Cases.2024; 12(22): 5229. CrossRef
Approaches and considerations in the endoscopic treatment of T1 colorectal cancer
Yunho Jung
The Korean Journal of Internal Medicine.2024; 39(4): 563. CrossRef
Optimal Surveillance of Metachronous Gastric Lesion after Endoscopic Resection of Early Gastric Cancer
Dong Chan Joo, Gwang Ha Kim
Gut and Liver.2024; 18(5): 781. CrossRef
Expanding Horizons: Unveiling the Clinical Features of Early Gastric Lymphoepithelioma-Like Carcinoma and the Potential of Endoscopic Resection as Curative Therapy
Jae Yong Park
Gut and Liver.2024; 18(5): 761. CrossRef
Histological Risk Factors for Lymph Node Metastasis in pT1 Colorectal Cancer: Does Submucosal Invasion Depth Really Matter?
Bing Yue, Mei Jia, Rui Xu, Guang-yong Chen, Mu-lan Jin
Current Medical Science.2024; 44(5): 1026. CrossRef
The risk factors of lymph node metastasis in early colorectal cancer: a predictive nomogram and risk assessment
Jiahui Xu, Fan Yin, Linlin Ren, Yushuang Xu, Congcong Min, Peng Zhang, Mengyu Cao, Xiaoyu Li, Zibin Tian, Tao Mao
International Journal of Colorectal Disease.2024;[Epub] CrossRef
Position statement of the World Endoscopy Organization: Role of endoscopy in screening, diagnosis, and treatment of esophageal superficial squamous neoplasiaia
Cesare Hassan, Giulio Antonelli, Philip Wai‐yan Chiu, Fabian Emura, Kenichi Goda, Prasad G. Iyer, Sameer Al Awadhi, Abed Al Lehibi, Vitor Arantes, Herbert Burgos, Cecilio L. Cerisoli, Sanford Dawsey, Peter Draganov, David Fleischer, Fernando Fluxá, Nicola
Digestive Endoscopy.2024;[Epub] CrossRef
Venous invasion and lymphatic invasion are correlated with the postoperative prognosis of pancreatic neuroendocrine neoplasm
Sho Kiritani, Junichi Arita, Yuichiro Mihara, Rihito Nagata, Akihiko Ichida, Yoshikuni Kawaguchi, Takeaki Ishizawa, Nobuhisa Akamatsu, Junichi Kaneko, Kiyoshi Hasegawa
Surgery.2023; 173(2): 365. CrossRef
Long-term outcomes after endoscopic versus surgical resection of T1 colorectal carcinoma
Hyun Jin Bae, Hoyeon Ju, Han Hee Lee, Jinsu Kim, Bo-In Lee, Sung Hak Lee, Daeyoun David Won, Yoon Suk Lee, In Kyu Lee, Young-Seok Cho
Surgical Endoscopy.2023; 37(2): 1231. CrossRef
Resection speed of endoscopic submucosal dissection according to the location of gastric neoplasia: a learning curve using cumulative sum analysis
Jun-Hyung Cho, So-Young Jin, Suyeon Park
Surgical Endoscopy.2023; 37(4): 2969. CrossRef
Endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: long-term follow-up in a Western center
Andreas Probst, Alanna Ebigbo, Stefan Eser, Carola Fleischmann, Tina Schaller, Bruno Märkl, Stefan Schiele, Bernd Geissler, Gernot Müller, Helmut Messmann
Clinical Endoscopy.2023; 56(1): 55. CrossRef
A Randomized Controlled Trial of Fibrin Glue to Prevent Bleeding After Gastric Endoscopic Submucosal Dissection
Hyun Deok Lee, Eunwoo Lee, Sang Gyun Kim, Cheol Min Shin, Jun Chul Park, Kee Don Choi, Seokyung Hahn, Soo-Jeong Cho
American Journal of Gastroenterology.2023; 118(5): 892. CrossRef
Endoscopic Resection of Undifferentiated Early Gastric Cancer
Yuichiro Hirai, Seiichiro Abe, Mai Ego Makiguchi, Masau Sekiguchi, Satoru Nonaka, Haruhisa Suzuki, Shigetaka Yoshinaga, Yutaka Saito
Journal of Gastric Cancer.2023; 23(1): 146. CrossRef
Pre-procedure oral administration of pronase improves efficacy of lugol chromoendoscopy in esophageal squamous cell carcinoma screening: a prospective, double-blinded, randomized, controlled trial
Xin Zhao, Meng Guo, Shaohua Zhu, Linhui Zhang, Tao Dong, Hui Luo, Weihua Yu, Jiangyi Zhu, Xiaotong Fan, Ying Han, Zhiguo Liu
Surgical Endoscopy.2023; 37(6): 4421. CrossRef
Endoscopic advances in the management of gastric cancer and premalignant gastric conditions
Erica Park, Makoto Nishimura, Priya Simoes
World Journal of Gastrointestinal Endoscopy.2023; 15(3): 114. CrossRef
Comparative Cost Analysis Between Endoscopic Resection and Surgery for Submucosal Colorectal Cancer
Soo Min Noh, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Byong Duk Ye, In Ja Park, Seok-Byung Lim, Jeong-Sik Byeon
Diseases of the Colon & Rectum.2023; 66(5): 723. CrossRef
Descriptive Analysis of Gastric Cancer Mortality in Korea, 2000-2020
Tung Hoang, Hyeongtaek Woo, Sooyoung Cho, Jeeyoo Lee, Sayada Zartasha Kazmi, Aesun Shin
Cancer Research and Treatment.2023; 55(2): 603. CrossRef
Endoscopically injectable and self‐crosslinkable hydrogel‐mediated stem cell transplantation for alleviating esophageal stricture after endoscopic submucosal dissection
Hyunsoo Chung, Soohwan An, Seung Yeop Han, Jihoon Jeon, Seung‐Woo Cho, Yong Chan Lee
Bioengineering & Translational Medicine.2023;[Epub] CrossRef
Deep learning-based clinical decision support system for gastric neoplasms in real-time endoscopy: development and validation study
Eun Jeong Gong, Chang Seok Bang, Jae Jun Lee, Gwang Ho Baik, Hyun Lim, Jae Hoon Jeong, Sung Won Choi, Joonhee Cho, Deok Yeol Kim, Kang Bin Lee, Seung-Il Shin, Dick Sigmund, Byeong In Moon, Sung Chul Park, Sang Hoon Lee, Ki Bae Bang, Dae-Soon Son
Endoscopy.2023; 55(08): 701. CrossRef
A 6-year nationwide population-based study on the current status of gastric endoscopic resection in Korea using administrative data
Jae Yong Park, Mi-Sook Kim, Beom Jin Kim, Jae Gyu Kim
Scientific Reports.2023;[Epub] CrossRef
Efficacy and Safety of ClearCut™ Knife H-type in Endoscopic Submucosal Dissection for Gastric Neoplasms: A Multicenter, Randomized Trial
Eun Jeong Gong, Hyun Lim, Sang Jin Lee, Do Hoon Kim
Journal of Gastric Cancer.2023; 23(3): 451. CrossRef
Endoscopic resection for local residual or recurrent cancer after definitive chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma
Yasuhiro Tani, Ryu Ishihara, Noriko Matsuura, Yuki Okubo, Yushi Kawakami, Hirohisa Sakurai, Takahiko Nakamura, Katsunori Matsueda, Muneaki Miyake, Satoki Shichijo, Akira Maekawa, Takashi Kanesaka, Sachiko Yamamoto, Yoji Takeuchi, Koji Higashino, Noriya Ue
Scientific Reports.2023;[Epub] CrossRef
Modified underwater endoscopic mucosal resection for intermediate-sized sessile colorectal polyps
Dong Hyun Kim, Seon-Young Park, Hye-Su You, Yong-Wook Jung, Young-Eun Joo, Dae-Seong Myung, Hyun-Soo Kim, Nah Ihm Kim, Seong-Jung Kim, Jae Kyun Ju
Frontiers in Medicine.2023;[Epub] CrossRef
Clinical Application of the Kyoto Classification of Gastritis
Gwang Ha Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(2): 89. CrossRef
Endoscopic Resection for Gastric Adenocarcinoma of the Fundic Gland Type: A Case Series
Hwa Jin Lee, Gwang Ha Kim, Dong Chan Joo, Moon Won Lee, Bong Eun Lee, Kyungbin Kim
The Korean Journal of Gastroenterology.2023; 81(6): 259. CrossRef
The optimal interval of surveillance gastroscopy after endoscopic resection for gastric neoplasia: a multicenter cohort study
Younghee Choe, Byung-Wook Kim, Tae Ho Kim, Jun-Won Chung, Jongwon Kim, Soo-Young Na, Joon Sung Kim
Surgical Endoscopy.2023; 37(10): 7556. CrossRef
External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection
Hyo-Joon Yang, Young-Il Kim, Ji Yong Ahn, Kee Don Choi, Sang Gyun Kim, Seong Woo Jeon, Jie-Hyun Kim, Sung Kwan Shin, Hyuk Lee, Wan Sik Lee, Gwang Ha Kim, Jae Myung Park, Woon Geon Shin, Il Ju Choi
Gut and Liver.2023; 17(4): 537. CrossRef
Outcomes of the Conventional versus Pocket-Creation Method for Endoscopic Submucosal Dissection of Gastric Body Tumors Using a Dual Knife: A Retrospective Study
Sang Pyo Lee, Hyun Joo Jang, Sea Hyub Kae, Jae Gon Lee
Gut and Liver.2023; 17(4): 547. CrossRef
LEARNING CURVE IN ESOPHAGEAL ENDOSCOPIC SUBMUCOSAL DISSECTION BY WESTERN ENDOSCOSPISTS TRAINED IN JAPAN: EXPERIENCE IN LATIN AMERICA
Josué ALIAGA RAMOS, Naohisa YOSHIDA, Rafiz ABDUL RANI, Vitor N ARANTES
Arquivos de Gastroenterologia.2023; 60(2): 208. CrossRef
Diagnostic Performance of Endoscopic Ultrasonography with Water-Filled Balloon Method for Superficial Esophageal Squamous Cell Carcinoma
Yugo Suzuki, Kosuke Nomura, Daisuke Kikuchi, Toshiro Iizuka, Mako Koseki, Yusuke Kawai, Takayuki Okamura, Yorinari Ochiai, Junnosuke Hayasaka, Yutaka Mitsunaga, Hiroyuki Odagiri, Satoshi Yamashita, Akira Matsui, Kenichi Ohashi, Shu Hoteya
Digestive Diseases and Sciences.2023; 68(10): 3974. CrossRef
Should All Undifferentiated Early Gastric Cancer Patients Undergoing Noncurative Endoscopic Resection Be Sent to the Operating Room?
Jung-Wook Kim, Albert C. Kim
Gut and Liver.2023; 17(5): 665. CrossRef
Comparing endoscopic mucosal resection with endoscopic submucosal dissection in colorectal adenoma and tumors: Meta-analysis and system review
Nian Wang, Lei Shu, Song Liu, Lin Yang, Tao Bai, Zhaohong Shi, Xinghuang Liu, Paolo Aurello
PLOS ONE.2023; 18(9): e0291916. CrossRef
Weighing the benefits of lymphadenectomy in early-stage colorectal cancer
Seung Min Baik, Ryung-Ah Lee
Annals of Surgical Treatment and Research.2023; 105(5): 245. CrossRef
Endoscopic treatment of colorectal polyps and early colorectal cancer
Yunho Jung
Journal of the Korean Medical Association.2023; 66(11): 642. CrossRef
Endoscopic submucosal dissection for early gastric cancer: It is time to consider the quality of its outcomes
Gwang Ha Kim
World Journal of Gastroenterology.2023; 29(43): 5800. CrossRef
A Retrospective Multicenter Study of Risk Factors, Stratification, and Prognosis of Lymph Node Metastasis in T1 and T2 Colorectal Cancer
Eui Myung Kim, Il Tae Son, Byung Chun Kim, Jun Ho Park, Byung Mo Kang, Jong Wan Kim
Journal of Clinical Medicine.2023; 12(24): 7744. CrossRef
A nomogram for predicting the risk of postoperative fever in elderly patients undergoing endoscopic submucosal dissection of the upper gastrointestinal tract
Zhixiang Xu, Jing Zhuang, Xin Zhu, Jun Yao
Medicine.2023; 102(50): e36438. CrossRef
Usage trends of colorectal endoscopic submucosal dissection according to hospital types based on nationwide claims data
Ji Eun Na, Bohyoung Kim, Sung Hoon Jung, Arum Choi, Sukil Kim, Tae-Oh Kim
Medicine.2023; 102(43): e35514. CrossRef
Long-term outcomes of endoscopic resection followed by additional surgery after non-curative resection in undifferentiated-type early gastric cancer: a nationwide multi-center study
Jie-Hyun Kim, Young-Il Kim, Ji Yong Ahn, Woon Geon Shin, Hyo-Joon Yang, Su Youn Nam, Byung-Hoon Min, Jae-Young Jang, Joo Hyun Lim, Wan Sik Lee, Bong Eun Lee, Moon Kyung Joo, Jae Myung Park, Hang Lak Lee, Tae-Geun Gweon, Moo In Park, Jeongmin Choi, Chung H
Surgical Endoscopy.2022; 36(3): 1847. CrossRef
A Simple Risk Scoring System for Predicting the Occurrence of Aspiration Pneumonia After Gastric Endoscopic Submucosal Dissection
Kyemyung Park, Na Young Kim, Ki Jun Kim, Chaerim Oh, Dongwoo Chae, So Yeon Kim
Anesthesia & Analgesia.2022; 134(1): 114. CrossRef
Long-term outcomes of endoscopic mucosal resection for early-stage esophageal adenocarcinoma
Kesha Oza, Tejasvi Peesay, Benjamin Greenspun, John E. Carroll, Shervin Shafa, Jay C. Zeck, Nadim G. Haddad, Marc Margolis, Puja Gaur Khaitan
Surgical Endoscopy.2022; 36(7): 5136. CrossRef
Long-Term Outcomes and Prognostic Factors of Superficial Esophageal Cancer in Patients Aged ≥ 65 Years
Jin Won Chang, Da Hyun Jung, Cheal Wung Huh, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
Frontiers in Medicine.2022;[Epub] CrossRef
Tumor Location as a Prognostic Factor in T1 Colorectal Cancer
Katsuro Ichimasa, Shin-ei Kudo, Yuta Kouyama, Kenichi Mochizuki, Yuki Takashina, Masashi Misawa, Yuichi Mori, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi
Journal of the Anus, Rectum and Colon.2022; 6(1): 9. CrossRef
Artificial Intelligence for Detecting and Delineating Margins of Early ESCC Under WLI Endoscopy
Wei Liu, Xianglei Yuan, Linjie Guo, Feng Pan, Chuncheng Wu, Zhongshang Sun, Feng Tian, Cong Yuan, Wanhong Zhang, Shuai Bai, Jing Feng, Yanxing Hu, Bing Hu
Clinical and Translational Gastroenterology.2022; 13(1): e00433. CrossRef
Machine Learning Model to Stratify the Risk of Lymph Node Metastasis for Early Gastric Cancer: A Single-Center Cohort Study
Ji-Eun Na, Yeong-Chan Lee, Tae-Jun Kim, Hyuk Lee, Hong-Hee Won, Yang-Won Min, Byung-Hoon Min, Jun-Haeng Lee, Poong-Lyul Rhee, Jae J. Kim
Cancers.2022; 14(5): 1121. CrossRef
Chinese consensus on prevention of colorectal neoplasia (2021, Shanghai)

Journal of Digestive Diseases.2022; 23(2): 58. CrossRef
Advances in the application of regenerative medicine in prevention of post-endoscopic submucosal dissection for esophageal stenosis
Jiaxin Wang, Yan Zhao, Peng Li, Shutian Zhang
Journal of Translational Internal Medicine.2022; 10(1): 28. CrossRef
Prolonged ischemia of the ileum and colon after surgical mucosectomy explains contraction and failure of “mucus free” bladder augmentation
Dániel Urbán, Gabriella Varga, Dániel Érces, Mahmoud Marei Marei, Raimondo Cervellione, David Keene, Anju Goyal, Tamás Cserni
Journal of Pediatric Urology.2022; 18(4): 500.e1. CrossRef
Safety and efficacy of prophylactic gastric open peroral endoscopic myotomy for prevention of post‐ESD stenosis: A case series (with video)
Won Dong Lee, Jae Sun Song, Byung Sun Kim, Min A. Yang, Young Jae Lee, Gum Mo Jung, Ji Woong Kim, Yong Keun Cho, Jin Woong Cho
Journal of Digestive Diseases.2022; 23(4): 220. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef
Endoscopic treatment for early gastric cancer
Ji Yong Ahn
Journal of the Korean Medical Association.2022; 65(5): 276. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Current status of the gastric cancer screening program in Korea
Young-Il Kim, Il Ju Choi
Journal of the Korean Medical Association.2022; 65(5): 250. CrossRef
Colorectális polypok ellátása
Szabolcs Ábrahám, Illés Tóth, Dániel Váczi, György Lázár
Magyar Sebészet.2022; 75(2): 155. CrossRef
Utility of a deep learning model and a clinical model for predicting bleeding after endoscopic submucosal dissection in patients with early gastric cancer
Ji Eun Na, Yeong Chan Lee, Tae Jun Kim, Hyuk Lee, Hong-Hee Won, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J Kim
World Journal of Gastroenterology.2022; 28(24): 2721. CrossRef
Rare primary rectal mucosa-associated lymphoid tissue lymphoma with curative resection by endoscopic submucosal dissection: A case report and review of literature
Yan Tao, Qiong Nan, Zi Lei, Ying-Lei Miao, Jun-Kun Niu
World Journal of Clinical Cases.2022; 10(21): 7599. CrossRef
Prevention of stricture after endoscopic submucosal dissection for esophageal cancer: intralesional steroid infusion using a spray tube
Jong Yeul Lee
Clinical Endoscopy.2022; 55(4): 516. CrossRef
Paneth Cell Carcinoma of the Stomach
Jun Wan Kim, Gwang Ha Kim, Kyung Bin Kim
The Korean Journal of Gastroenterology.2022; 80(1): 34. CrossRef
Composite scoring system and optimal tumor budding cut-off number for estimating lymph node metastasis in submucosal colorectal cancer
Jeong-ki Kim, Ye-Young Rhee, Jeong Mo Bae, Jung Ho Kim, Seong-Joon Koh, Hyun Jung Lee, Jong Pil Im, Min Jung Kim, Seung-Bum Ryoo, Seung-Yong Jeong, Kyu Joo Park, Ji Won Park, Gyeong Hoon Kang
BMC Cancer.2022;[Epub] CrossRef
Multidisciplinary Treatment Strategy for Early Colon Cancer: A Review-An English Version
Gyung Mo Son, Su Bum Park, Tae Un Kim, Byung-Soo Park, In Young Lee, Joo-Young Na, Dong Hoon Shin, Sang Bo Oh, Sung Hwan Cho, Hyun Sung Kim, Hyung Wook Kim
Journal of the Anus, Rectum and Colon.2022; 6(4): 203. CrossRef
Extragastric Metastasis of Early Gastric Cancer After Endoscopic Submucosal Dissection With Lymphovascular Invasion and Negative Resected Margins
Han Myung Lee, Yoonjin Kwak, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
Journal of Gastric Cancer.2022; 22(4): 339. CrossRef
Comparison between a novel core knife and the conventional IT knife 2 for endoscopic submucosal dissection of gastric mucosal lesions
Myeongsoon Park, Jin Wook Lee, Dong Woo Shin, Jungseok Kim, Yoo Jin Lee, Ju Yup Lee, Kwang Bum Cho
Clinical Endoscopy.2022; 55(6): 767. CrossRef
Need for careful endoscopic evaluation of large gastric neoplasms before endoscopic submucosal dissection
Seung Woo Lee
Clinical Endoscopy.2022; 55(6): 753. CrossRef
Regression of gastric endoscopic submucosal dissection induced polypoid nodular scar after Helicobacter pylori eradication: A case report
Byung Chul Jin, Ae Ri Ahn, Seong-Hun Kim, Seung Young Seo
World Journal of Clinical Cases.2022; 10(34): 12793. CrossRef
Simultaneous analysis of tumor-infiltrating immune cells density, tumor budding status, and presence of lymphoid follicles in CRC tissue
Adam R. Markowski, Anna J. Markowska, Wiktoria Ustymowicz, Anna Pryczynicz, Katarzyna Guzińska-Ustymowicz
Scientific Reports.2022;[Epub] CrossRef
Role of Endoscopy in Management of Upper Gastrointestinal Cancers
Jeff Liang, Yi Jiang, Yazan Abboud, Srinivas Gaddam
Diseases.2022; 11(1): 3. CrossRef
Association between severe hepatic steatosis examined by Fibroscan and the risk of high-risk colorectal neoplasia
Kwang Woo Kim, Hyoun Woo Kang, Hosun Yoo, Yukyung Jun, Hyun Jung Lee, Jong Pil Im, Ji Won Kim, Joo Sung Kim, Seong-Joon Koh, Yong Jin Jung, Atsushi Hosui
PLOS ONE.2022; 17(12): e0279242. CrossRef
Long-term outcomes and clinical safety of expanded indication early gastric cancer treated with endoscopic submucosal dissection versus surgical resection: a meta-analysis
Xing Xu, Guoliang Zheng, Na Gao, Zhichao Zheng
BMJ Open.2022; 12(12): e055406. CrossRef
Long-Term Safety of Delayed Surgery After Upfront Endoscopic Resection for Early Gastric Cancer: A Propensity Matched Study
Ji Eun Na, Yeong Gi Kim, Tae Jun Kim, Hyuk Lee, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Seon Yeong Baek, Min Su Park, Poong-Lyul Rhee, Jae J. Kim
Annals of Surgical Oncology.2021; 28(1): 106. CrossRef
Incidence rates, risk factors, and outcomes of aspiration pneumonia after gastric endoscopic submucosal dissection: A systematic review and meta‐analysis
Dong Tang, Fuxiang Yuan, Xiaoying Ma, Haixia Qu, Yuan Li, Weiwei Zhang, Huan Ma, Haiping Liu, Yan Yang, Lin Xu, Yuqiang Gao, Shuhui Zhan
Journal of Gastroenterology and Hepatology.2021; 36(6): 1457. CrossRef
Clinical feasibility and oncologic safety of primary endoscopic submucosal dissection for clinical submucosal invasive early gastric cancer
Ji Eun Na, Hyuk Lee, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Kyoung-Mee Kim, Jae J. Kim
Journal of Cancer Research and Clinical Oncology.2021; 147(10): 3051. CrossRef
Endoscopic resections for superficial esophageal squamous cell epithelial neoplasia: focus on histological discrepancies between biopsy and resected specimens
Lang Yang, Hua Jin, Xiao-li Xie, Yang-tian Cao, Zhen-hua Liu, Na Li, Peng Jin, Yu-qi He, Jian-qiu Sheng
BMC Gastroenterology.2021;[Epub] CrossRef
Atypical Scar Patterns after Gastric Endoscopic Submucosal Dissection
Bomin Kim, Beom Jin Kim, Hong Jip Yoon, Hyunsuk Lee, Jae Yong Park, Chang Hwan Choi, Jae Gyu Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2021; 21(1): 72. CrossRef
Endoscopic Submucosal Dissection versus Surgery for Undifferentiated-Type Early Gastric Cancer: A Systematic Review and Meta-Analysis
Cheal-Wung Huh, Dae Won Ma, Byung-Wook Kim, Joon Sung Kim, Seung Jae Lee
Clinical Endoscopy.2021; 54(2): 202. CrossRef
Role of Endoscopic Ultrasound in Selecting Superficial Esophageal Cancers for Endoscopic Resection
Jinju Choi, Hyunsoo Chung, Ayoung Lee, Jue Lie Kim, Soo-Jeong Cho, Sang Gyun Kim
The Annals of Thoracic Surgery.2021; 111(5): 1689. CrossRef
Recent advances in early esophageal cancer: diagnosis and treatment based on endoscopy
Hang Yang, Bing Hu
Postgraduate Medicine.2021; 133(6): 665. CrossRef
Endoscopic Resection of Gastric Cancer
Ga Hee Kim, Hwoon-Yong Jung
Gastrointestinal Endoscopy Clinics of North America.2021; 31(3): 563. CrossRef
Gastric Mucosa-Associated Lymphoid Tissue Lymphomas Diagnosed by Jumbo Biopsy Using Endoscopic Submucosal Dissection: A Case Report
Jian Han, Jun Wang, Hua-ping Xie
Frontiers in Medicine.2021;[Epub] CrossRef
Considerations for Endoscopic Treatment of Undifferentiated-type Early Gastric Cancer
Kyoungwon Jung
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2021; 21(2): 103. CrossRef
Papillary Adenocarcinoma
Tae-Se Kim, Byung-Hoon Min
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2021; 21(2): 122. CrossRef
Early gastrointestinal cancer: The application of artificial intelligence
Hang Yang, Bing Hu
Artificial Intelligence in Gastrointestinal Endoscopy.2021; 2(4): 185. CrossRef
Successful Endoscopic Resection of Primary Rectal Mucosa-Associated Lymphoid Tissue Lymphoma by Endoscopic Submucosal Dissection: A Case Report
Jian Han, Zhe Zhu, Chao Zhang, Hua-ping Xie
Frontiers in Medicine.2021;[Epub] CrossRef
Assessment of the Diagnostic Performance of Endoscopic Ultrasonography After Conventional Endoscopy for the Evaluation of Esophageal Squamous Cell Carcinoma Invasion Depth
Ryu Ishihara, Junki Mizusawa, Ryoji Kushima, Noriko Matsuura, Tomonori Yano, Tomoko Kataoka, Haruhiko Fukuda, Noboru Hanaoka, Toshiyuki Yoshio, Seiichiro Abe, Yoshinobu Yamamoto, Shinji Nagata, Hiroyuki Ono, Masashi Tamaoki, Naohiro Yoshida, Kohei Takizaw
JAMA Network Open.2021; 4(9): e2125317. CrossRef
Variation in Diagnosis, Treatment, and Outcome of Esophageal Cancer in a Regionalized Care System in Ontario, Canada
Steven Habbous, Olga Yermakhanova, Katharina Forster, Claire M. B. Holloway, Gail Darling
JAMA Network Open.2021; 4(9): e2126090. CrossRef
Risk Stratification of T1 Colorectal Cancer Metastasis to Lymph Nodes: Current Status and Perspective
Katsuro Ichimasa, Shin-ei Kudo, Hideyuki Miyachi, Yuta Kouyama, Masashi Misawa, Yuichi Mori
Gut and Liver.2021; 15(6): 818. CrossRef
Close Observation versus Additional Surgery after Noncurative Endoscopic Resection of Esophageal Squamous Cell Carcinoma
Byeong Geun Song, Ga Hee Kim, Charles J. Cho, Hyeong Ryul Kim, Yang Won Min, Hyuk Lee, Byung-Hoon Min, Ho June Song, Yong-Hee Kim, Jun Haeng Lee, Hwoon-Yong Jung, Jae Ill Zo, Young Mog Shim
Digestive Surgery.2021; 38(3): 247. CrossRef

18,907 View
1,178 Download
105 Web of Science
104 Crossref

Original Articles

Quality Indicators for the Detection of Helicobacter pylori-Negative Early Gastric Cancer: A Retrospective Observational Study: Fumiaki Ishibashi, Konomi Kobayashi, Keita Fukushima, Ryu Tanaka, Tomohiro Kawakami, Junko Kato, Kazuaki Sugihara; Clin Endosc 2020;53(6):698-704. Published online March 13, 2020; DOI: https://doi.org/10.5946/ce.2019.203

Abstract PDF PubReader ePub

Background
/Aims: While Helicobacter pylori (HP)-negative gastric cancer is frequently reported, little is known about the predictors for detecting HP-negative early gastric cancer (EGC). We aimed to evaluate the predictors for the detection of HP-negative EGC.
Methods
We retrospectively reviewed 13,477 consecutive asymptomatic cases where upper endoscopy was performed by nine physicians from April 2017 to March 2019 and analyzed the detection rate of high-risk lesions (HRLs), including EGC, tubular adenoma, and lymphoma, according to the status of HP infection. The observation time was corrected for multiple regression analyses.
Results
For all physicians, the average observation time for screening HP-eradicated and -naïve patients was shorter than that for screening HP-positive patients (p<0.05). Multiple regression analyses revealed that the observation time in the three groups was an independent predictor for detecting HRLs in HP-eradicated patients (p=0.03106, 0.01263, and 0.02485, respectively), while experience of endoscopy was an independent predictor for detecting HRLs in HP-naïve patients (p=0.02638).
Conclusions
While observation time during screening endoscopy was a quality indicator for detecting HRLs in HP-eradicated patients, experience of endoscopy was a quality indicator for detecting HRLs in HP-naïve patients.

Citations

Citations to this article as recorded by

Management of epithelial precancerous conditions and early neoplasia of the stomach (MAPS III): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG) and European Society of Pathology (ESP) Guideli
Mário Dinis-Ribeiro, Diogo Libânio, Hugo Uchima, Manon C.W. Spaander, Jan Bornschein, Tamara Matysiak-Budnik, Georgios Tziatzios, João Santos-Antunes, Miguel Areia, Nicolas Chapelle, Gianluca Esposito, Gloria Fernandez-Esparrach, Lumir Kunovsky, Mónica Ga
Endoscopy.2025; 57(05): 504. CrossRef
A mathematical simulation model to determine the optimal endoscopic screening strategy for detection of H. pylori-naïve gastric neoplasms
Fumiaki Ishibashi, Kosuke Okusa, Yoshitaka Tokai, Toshiaki Hirasawa, Tomohiro Kawakami, Kentaro Mochida, Yuka Yanai, Chizu Yokoi, Yuko Hayashi, Shun-ichiro Ozawa, Koji Uraushihara, Yohei Minato, Hiroyuki Nakanishi, Hiroya Ueyama, Mikinori Kataoka, Yuzo To
Gastric Cancer.2024; 27(5): 1078. CrossRef
Exploring quality indicators for the detection of Helicobacter pylori-naïve gastric cancer: a cross-sectional nationwide survey
Fumiaki Ishibashi, Toshiaki Hirasawa, Hiroya Ueyama, Yohei Minato, Sho Suzuki
Clinical Endoscopy.2023; 56(4): 460. CrossRef
A Close Follow-Up Strategy in the Short Period of Time after Helicobacter pylori Eradication Contributes to Earlier Detection of Gastric Cancer
Fumiaki Ishibashi, Sho Suzuki, Mizuki Nagai, Kentaro Mochida, Konomi Kobayashi, Tetsuo Morishita
Digestion.2023; 104(3): 165. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Tailored eradication strategy vs concomitant therapy for Helicobacter pylori eradication treatment in Korean patients
Youn I Choi, Jun-Won Chung, Kyoung Oh Kim, Kwang An Kwon, Yoon Jae Kim, Jung Ho Kim, Ja Young Seo, Dong Kyun Park
World Journal of Gastroenterology.2021; 27(31): 5247. CrossRef
Quality management system for screening esophagogastroduodenoscopy improves detection of Helicobacter pylori-negative interval gastric cancer
Fumiaki Ishibashi, Konomi Kobayashi, Tomohiro Kawakami, Ryu Tanaka, Kazuaki Sugihara, Satoshi Baba
Endoscopy International Open.2021; 09(12): E1900. CrossRef
Quality Indicator for Gastric Cancer Detection Based on Helicobacter pylori Status
Jae Myung Park
Clinical Endoscopy.2020; 53(6): 629. CrossRef

6,141 View
207 Download
9 Web of Science
9 Crossref

Endoscopic Factors that Can Predict Histological Ulcerations in Early Gastric Cancers: Jaesin Lee, Byung-Wook Kim, Cheal Wung Huh, Joon Sung Kim, Lee-So Maeng; Clin Endosc 2020;53(3):328-333. Published online January 7, 2020; DOI: https://doi.org/10.5946/ce.2019.133

Abstract PDF PubReader ePub

Background
/Aims: Predicting histological ulceration in early gastric cancer (EGC) during endoscopic examination is crucial for endoscopists deciding on the treatment modality. The aim of this study was to investigate the endoscopic factors that can predict histological ulcerations in EGCs.
Methods
We retrospectively analyzed patients who underwent endoscopic submucosal dissection (ESD) for EGC. Clinical features and endoscopic characteristics of EGC such as location, histological differentiation, longest diameter, tumor morphology, mucosal break, converging fold, color change, and surface irregularity were reviewed. Histological ulceration was defined based on ESD specimens.
Results
A total of 633 EGC lesions from 613 patients were included and histological ulcerations were found in 90 lesions (14.2%). Presence of converging folds, tumor morphology, and color changes on endoscopic examination were related to histological ulceration in the univariate analysis and converging folds along with color changes were statistically significant factors in the multivariate analysis. Kaplan–Meier analysis showed that patients with histological ulcerations in EGCs tended to have higher marginal recurrence rates.
Conclusions
Mucosal breaks are not equivalent to histological ulcerations. Rather, the existence of converging folds and color changes during endoscopic examination suggest histological ulcerations. Endoscopists should consider these factors when they decide the treatment modality for EGCs.

Citations

Citations to this article as recorded by

Clinical Impact of Proton Pump Inhibitor and Potassium-Competitive Acid Blocker for Predicting the Curability of Endoscopic Resection in Ulcerative Early Gastric Cancer
Konomu Uno, Takaya Shimura, Shingo Inaguma, Keita Kuroyanagi, Ruriko Nishigaki, Takuya Kanno, Makiko Sasaki, Shigeki Fukusada, Naomi Sugimura, Yusuke Mizuno, Takayuki Nukui, Yuki Kojima, Mamoru Tanaka, Keiji Ozeki, Eiji Kubota, Satoru Takahashi, Hiromi Ka
Digestion.2024; 105(3): 192. CrossRef
Identification of maximal tumor size associated with negligible lymph node metastasis for endoscopic submucosal dissection of undifferentiated-type early gastric cancer
Sung Eun Oh, Soomin Ahn, Kyoung-Mee Kim, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Ji Yeong An
Gastric Cancer.2024; 27(4): 850. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef
Construction and analysis of an ulcer risk prediction model after endoscopic submucosal dissection for early gastric cancer
San-Dong Gong, Huan Li, Yi-Bin Xie, Xiao-Hui Wang
World Journal of Gastrointestinal Oncology.2022; 14(9): 1823. CrossRef
Long‑term outcome of the endoscopic submucosal dissection of early gastric cancer: A comparison between patients with and without liver cirrhosis
Seung Kim, Moon Joo, Ah-Young Yoo, Seong Kim, Won Kim, Beom Lee, Jong Park, Hoon Chun, Sang Lee
Oncology Letters.2022;[Epub] CrossRef
Discrepancy between endoscopic and pathological ulcerative findings in clinical intramucosal early gastric cancer
Yohei Yabuuchi, Kohei Takizawa, Naomi Kakushima, Noboru Kawata, Masao Yoshida, Yoichi Yamamoto, Yoshihiro Kishida, Sayo Ito, Kenichiro Imai, Hirotoshi Ishiwatari, Kinichi Hotta, Hiroyuki Matsubayashi, Etsuro Bando, Masanori Terashima, Takashi Sugino, Hiro
Gastric Cancer.2021; 24(3): 691. CrossRef
What is the Most Precise Endoscopic Finding for Predicting the Clinicopathological Behaviors in Ulcerative Early Gastric Cancer?
Youngdae Kim
Clinical Endoscopy.2020; 53(3): 249. CrossRef

5,965 View
151 Download
8 Web of Science
8 Crossref

Risk Factors and Clinical Outcomes of Non-Curative Resection in Patients with Early Gastric Cancer Treated with Endoscopic Submucosal Dissection: A Retrospective Multicenter Study in Korea: Si Hyung Lee, Min Cheol Kim, Seong Woo Jeon, Kang Nyeong Lee, Jong Jae Park, Su Jin Hong, Korean Society of Gastrointestinal Endoscopy Endoscopic Submucosal Dissection Research Group; Clin Endosc 2020;53(2):196-205. Published online October 25, 2019; DOI: https://doi.org/10.5946/ce.2019.123

Abstract PDF PubReader ePub

Background
/Aims: The purpose of this study was to investigate the risk factors and long-term clinical outcomes of non-curative resection (NCR) in a large-scale patient population.
Methods
We retrospectively analyzed the clinical data of 3,094 patients who underwent endoscopic submucosal dissection (ESD) of early gastric cancer from March 2005 to March 2018 at 13 institutions in Korea. We analyzed the risk factors for NCR and the survival between patients with curative resection and those with NCR with no additional treatment.
Results
The NCR rate was 21.4% (661/3,094). In multivariate regression analysis, the risk factors affecting NCR with ESD were old age, undifferentiated tumor, tumor location in the upper body, tumor size ≥2 cm, and presence of an ulcer. In Cox proportional hazard regression analysis, tumor size ≥2 cm, submucosal invasion, positive horizontal margin, and lymphovascular invasion were risk factors for local recurrence. In Kaplan-Meier analysis, there was no statistically significant difference in the overall survival between the two groups (log-rank p=0.788). However, disease-specific survival was significantly lower in the NCR group (log-rank p=0.038).
Conclusions
Clinicians should be aware of the risk factors for NCR and local recurrence after ESD for early gastric cancer, and should consider providing additional treatment after NCR.

Citations

Citations to this article as recorded by

Management Strategy of Non-curative ESD in Gastric Cancer: Curative Criteria, and the Critical Building Block for Determining Beyond It
Hyuk Lee
Journal of Gastric Cancer.2025; 25(1): 210. CrossRef
Enhancing Lymph Node Metastasis Risk Prediction in Early Gastric Cancer Through the Integration of Endoscopic Images and Real-World Data in a Multimodal AI Model
Donghoon Kang, Han Jo Jeon, Jie-Hyun Kim, Sang-Il Oh, Ye Seul Seong, Jae Young Jang, Jung-Wook Kim, Joon Sung Kim, Seung-Joo Nam, Chang Seok Bang, Hyuk Soon Choi
Cancers.2025; 17(5): 869. CrossRef
Management of epithelial precancerous conditions and early neoplasia of the stomach (MAPS III): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG) and European Society of Pathology (ESP) Guideli
Mário Dinis-Ribeiro, Diogo Libânio, Hugo Uchima, Manon C.W. Spaander, Jan Bornschein, Tamara Matysiak-Budnik, Georgios Tziatzios, João Santos-Antunes, Miguel Areia, Nicolas Chapelle, Gianluca Esposito, Gloria Fernandez-Esparrach, Lumir Kunovsky, Mónica Ga
Endoscopy.2025; 57(05): 504. CrossRef
Non-Curative Endoscopic Submucosal Dissection: Current Concepts, Pitfalls and Future Perspectives
João Santos-Antunes
Journal of Clinical Medicine.2025; 14(7): 2488. CrossRef
Risk factors for pathological upgrading and noncurative resection in patients with gastric mucosal lesions after endoscopic submucosal dissection
Pingjiang Wang, Xu Zhao, Ruicai Wang, Dong Xu, Haiping Yang
BMC Gastroenterology.2024;[Epub] CrossRef
Endoscopic and clinicopathological features of early gastric papillary adenocarcinoma
Zhenxiang Zuo, Xing Qi, Xiujie Cui, Bin Yu, Huimin Zhang, Honglei Wu
Frontiers in Oncology.2024;[Epub] CrossRef
Comprehensive analysis of risk factors associated with submucosal invasion in patients with early-stage gastric cancer
Bin-Bin Yan, Li-Na Cheng, Hui Yang, Xiu-Ling Li, Xiu-Qi Wang
World Journal of Gastroenterology.2024; 30(47): 5007. CrossRef
Pathology Reporting of Gastric Endoscopic Resections: Recommendations From the International Collaboration on Cancer Reporting
Chanjuan Shi, Fleur Webster, Iris D. Nagtegaal, Michael J. Bourke, Seung-mo Hong, M. Priyanthi Kumarasinghe, Alfred K. Lam, Gregory Lauwers, Maria O’Donovan, Rachel S. van der Post, Tetsuo Ushiku, Michael Vieth, Christina Selinger
Gastroenterology.2023; 164(7): 1039. CrossRef
Nomogram for pre-procedural prediction of non-curative endoscopic resection in patients with early gastric cancer
So Young Han, Hong Jin Yoon, Jie-Hyun Kim, Hye Sun Lee, Jaeyoung Chun, Young Hoon Youn, Hyojin Park
Surgical Endoscopy.2023; 37(6): 4594. CrossRef
Endoscopic submucosal dissection for early gastric cancer: It is time to consider the quality of its outcomes
Gwang Ha Kim
World Journal of Gastroenterology.2023; 29(43): 5800. CrossRef
Cancer Patient Perception Survey to Develop Korean Medicine Clinical Practice Guidelines for Gastric Cancer
Dong Hyeon Kim, Jong Hee Kim, Ji Hye Park, Hwa Seung Yoo, Hyeong Joon Jeon, So Jung Park
Journal of Physiology & Pathology in Korean Medicine.2023; 37(4): 81. CrossRef
Endoscopic treatment for early gastric cancer
Ji Yong Ahn
Journal of the Korean Medical Association.2022; 65(5): 276. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Long‑term outcome of the endoscopic submucosal dissection of early gastric cancer: A comparison between patients with and without liver cirrhosis
Seung Kim, Moon Joo, Ah-Young Yoo, Seong Kim, Won Kim, Beom Lee, Jong Park, Hoon Chun, Sang Lee
Oncology Letters.2022;[Epub] CrossRef
Clinico-pathologic determinants of non-e-curative outcome following en-bloc endoscopic submucosal dissection in patients with early gastric neoplasia
Kidane Siele Embaye, Chao Zhang, Matiwos Araya Ghebrehiwet, Zhihao Wang, Fengdi Zhang, Liwei Liu, Shenghui Qin, Lingzhi Qin, Jun Wang, Xi Wang
BMC Cancer.2021;[Epub] CrossRef
Factors associated with overall survival in early gastric cancer patients who underwent additional surgery after endoscopic submucosal dissection
Zhi Zheng, Fan-Di Bu, Hao Chen, Jie Yin, Rui Xu, Jun Cai, Jun Zhang, Hong-Wei Yao, Zhong-Tao Zhang
World Journal of Clinical Cases.2021; 9(10): 2192. CrossRef
Establishing Machine Learning Models to Predict Curative Resection in Early Gastric Cancer with Undifferentiated Histology: Development and Usability Study
Chang Seok Bang, Ji Yong Ahn, Jie-Hyun Kim, Young-Il Kim, Il Ju Choi, Woon Geon Shin
Journal of Medical Internet Research.2021; 23(4): e25053. CrossRef
Population Attributable Fraction of Helicobacter pylori Infection–Related Gastric Cancer in Korea: A Meta-Analysis
Yoon Park, Moran Ki
Cancer Research and Treatment.2021; 53(3): 744. CrossRef
Very low rate of residual neoplasia after non-curative endoscopic submucosal dissection: a western single-center experience
João Santos-Antunes, Margarida Marques, Fátima Carneiro, Guilherme Macedo
European Journal of Gastroenterology & Hepatology.2021; 33(9): 1161. CrossRef
Editors' Choice of Noteworthy Clinical Endoscopy Publications in the First Decade
Gwang Ha Kim, Kwang An Kwon, Do Hyun Park, Jimin Han
Clinical Endoscopy.2021; 54(5): 633. CrossRef
Non-Curative Resection: Should Clinicians Consider Providing Additional Surgery for All Patients?
Waku Hatta, Takuji Gotoda, Atsushi Masamune
Clinical Endoscopy.2020; 53(2): 109. CrossRef
Protocol for expanded indications of endoscopic submucosal dissection for early gastric cancer in China: a multicenter, ambispective, observational, open-cohort study
Zhi Zheng, Jie Yin, Ziyu Li, Yingjiang Ye, Bo Wei, Xin Wang, Yantao Tian, Mengyi Li, Qian Zhang, Na Zeng, Rui Xu, Guangyong Chen, Jie Zhang, Peng Li, Jun Cai, Hongwei Yao, Jun Zhang, Zhongtao Zhang, Shutian Zhang
BMC Cancer.2020;[Epub] CrossRef
Predictive Factors and Long-Term Outcomes of Early Gastric Carcinomas in Patients with Non-Curative Resection by Endoscopic Submucosal Dissection

Ping Xu, Yun Wang, Yini Dang, Qin Huang, Jianhua Wang, Weifeng Zhang, Yifeng Zhang, Guoxin Zhang
Cancer Management and Research.2020; Volume 12: 8037. CrossRef

6,885 View
333 Download
24 Web of Science
24 Crossref

Review

Assessment of Endoscopic Gastric Atrophy according to the Kimura-Takemoto Classification and Its Potential Application in Daily Practice: Duc Trong Quach, Toru Hiyama; Clin Endosc 2019;52(4):321-327. Published online July 22, 2019; DOI: https://doi.org/10.5946/ce.2019.072

Abstract PDF PubReader ePub

The assessment of endoscopic gastric atrophy (EGA) according to the Kimura-Takemoto classification has been reported to correlate well with histological assessment. Although agreement among beginner endoscopists was less than that among experienced endoscopists, it has been shown that agreement level could markedly improve and remained stable after proper training. Several cohort studies have consistently shown that the severity of EGA at baseline is significantly associated with the presence of advanced precancerous gastric lesions and gastric cancer, as well as the development of gastric cancer in future. Patients with moderate-to-severe EGA still have high risk of gastric cancer even after successful Helicobacter pylori eradication and should be candidates for gastric cancer surveillance. The assessment of EGA, therefore, could be used as a preliminary tool to identify individuals at high risk for gastric cancer. In this paper, we review the agreement on mucosal atrophy assessment between the Kimura-Takemoto classification and histology as well as the potential application of this endoscopic classification to identify precancerous gastric lesions and gastric cancer in daily practice.

Citations

Citations to this article as recorded by

Relationship between gastric mucosal atrophy, cystic dilatation, and histopathological characteristics
Yang-Kun Wang, Ping Li, Hai-Ying He, Fa-Shun Zhang, Xiao-Ling Jiang, Ren-Bing Zhang, Su-Nan Wang, Si-Liang Xu
BMC Gastroenterology.2025;[Epub] CrossRef
ACG Clinical Guideline: Diagnosis and Management of Gastric Premalignant Conditions
Douglas R. Morgan, Juan E. Corral, Dan Li, Elizabeth A. Montgomery, Arnoldo Riquelme, John J. Kim, Bryan Sauer, Shailja C. Shah
American Journal of Gastroenterology.2025; 120(4): 709. CrossRef
A study of clinical features of atrophic gastritis in patients with Sjögren’s disease
Susumu Nishiyama, Keiji Ohashi, Tetsushi Aita, Yasuhiko Yoshinaga
Modern Rheumatology.2025;[Epub] CrossRef
Endoscopic diagnosis and prevalence of early gastric cancer in India: A prospective study
Ashutosh Mohapatra, Sonmoon Mohapatra, Shruti Mahawar, Krushna Chandra Pani, Nachiketa Mohapatra, Mohan Ramchandani, Nageshwar Reddy, Mahesh K. Goenka, Noriya Uedo
DEN Open.2024;[Epub] CrossRef
Clinical and morphological characteristics of patients with chronic gastritis and high risk of gastric cancer
A. S. Tertychnyy, D. D. Protsenko, N. V. Pachuashvili, D. P. Nagornaya, P. V. Pavlov, A. P. Kiruhin, A. A. Fedorenko
Experimental and Clinical Gastroenterology.2024; (9): 107. CrossRef
Comparison between the GastroPanel test and the serum pepsinogen assay interpreted with the ABC method—A prospective study
Sun‐Young Lee, Yeon‐Sun Ahn, Hee‐Won Moon
Helicobacter.2024;[Epub] CrossRef
The value of LCI-based modified Kyoto classification risk scoring system in predicting the risk of early gastric cancer
Chao Gao, Guanpo Zhang, Jin Zheng, Yunmeng Zheng, Wulian Lin, Guilin Xu, Yixiang You, Dazhou Li, Wen Wang
Scandinavian Journal of Gastroenterology.2024; 59(7): 859. CrossRef
Incidence of Gastric Adenocarcinoma in Those With Gastric Atrophy: A Systematic Review
Eoghan Burke, Patricia Harkins, Mayilone Arumugasamy
Cureus.2024;[Epub] CrossRef
Endoscopic and clinical characteristics of autoimmune atrophic gastritis: Retrospective study
Kareem Khalaf, Yusuke Fujiyoshi, Robert Bechara
Endoscopy International Open.2024;[Epub] CrossRef
Identification of serum microRNAs as potential diagnostic biomarkers for detecting precancerous lesions of gastric cancer
Hajime Otsu, Sho Nambara, Qingjiang Hu, Yuichi Hisamatsu, Takeo Toshima, Kazuki Takeishi, Yusuke Yonemura, Takaaki Masuda, Eiji Oki, Koshi Mimori
Annals of Gastroenterological Surgery.2023; 7(1): 63. CrossRef
Evolution of the Correa's cascade steps: A long-term endoscopic surveillance among non-ulcer dyspepsia and gastric ulcer after H. pylori eradication
Hsiu-Chi Cheng, Yao-Jong Yang, Hsiao-Bai Yang, Yu-Ching Tsai, Wei-Lun Chang, Chung-Tai Wu, Hsin-Yu Kuo, Yu-Ting Yu, Er-Hsiang Yang, Wei-Chun Cheng, Wei-Ying Chen, Bor-Shyang Sheu
Journal of the Formosan Medical Association.2023; 122(5): 400. CrossRef
Vietnam Association of Gastroenterology (VNAGE) consensus on the management of Helicobacter pylori infection
Duc Trong Quach, Bang Hong Mai, Mien Kieu Tran, Long Van Dao, Huy Van Tran, Khanh Truong Vu, Khien Van Vu, Ho Thi-Thu Pham, Hoang Huu Bui, Dung Dang-Quy Ho, Dung Tuan Trinh, Vinh Thuy Nguyen, Thai Hong Duong, Tuong Thi-Khanh Tran, Ha Thi-Viet Nguyen, Thin
Frontiers in Medicine.2023;[Epub] CrossRef
Endoscopic Screening for Missed Lesions of Synchronous Multiple Early Gastric Cancer during Endoscopic Submucosal Dissection
Jiangnan Wan, Yi Fang, Haizhong Jiang, Bujiang Wang, Lei Xu, Chunjiu Hu, Honghui Chen, Xiaoyun Ding, Tatsuya Toyokawa
Gastroenterology Research and Practice.2023; 2023: 1. CrossRef
Morphometric features of gastric mucosa in atrophic gastritis: A different pattern between corpus and antrum
Xue-Mei Lin, Li Wang, Chun-Hui Xi, Jun Wang, Xian-Fei Wang, Qiong Wang, Cong Yuan
Medicine.2023; 102(14): e33480. CrossRef
Predicting reflux symptom recurrence: The impact of gastroesophageal junction indicators and body mass index among outpatients
Qing Wang, Junhui Lu, Yue Sui, Jing Fan, Jinnan Ren, Zhenzhen Wang, Xing Chen
Experimental and Therapeutic Medicine.2023;[Epub] CrossRef
Helicobacter pylori intragastric colonization and migration: Endoscopic manifestations and potential mechanisms
Tong Mu, Zhi-Ming Lu, Wen-Wen Wang, Hua Feng, Yan Jin, Qian Ding, Li-Fen Wang
World Journal of Gastroenterology.2023; 29(30): 4616. CrossRef
Factors associated with heterochronic gastric cancer development post-endoscopic mucosal dissection in early gastric cancer patients
Bing Xie, Yun Xia, Xia Wang, Yan Xiong, Shao-Bo Chen, Jie Zhang, Wei-Wei He
World Journal of Gastrointestinal Oncology.2023; 15(9): 1644. CrossRef
Kimura–Takemoto Classification: A Tool to Predict Gastric Intestinal Metaplasia Progression to Advanced Gastric Neoplasia
Leyla Maric, Daniel Castaneda, Harjinder Singh, Pablo Bejarano, Brenda Jimenez Cantisano, Fernando J. Castro
Digestive Diseases and Sciences.2022; 67(8): 4092. CrossRef
Consistency between the endoscopic Kyoto classification and pathological updated Sydney system for gastritis: A cross‐sectional study
Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Tatsuya Matsuno, Nariaki Odawara, Akira Toyoshima, Kosuke Sakitani, Hidenobu Watanabe, Mitsuhiro Fujishiro, Hidekazu Suzuki
Journal of Gastroenterology and Hepatology.2022; 37(2): 291. CrossRef
Diagnostic Accuracy of H. pylori Status by Conventional Endoscopy: Time-Trend Change After Eradication and Impact of Endoscopic Image Quality
Duc Trong Quach, Rika Aoki, Akiko Iga, Quang Dinh Le, Toru Kawamura, Ken Yamashita, Shinji Tanaka, Masaharu Yoshihara, Toru Hiyama
Frontiers in Medicine.2022;[Epub] CrossRef
Relevance of pepsinogen, gastrin, and endoscopic atrophy in the diagnosis of autoimmune gastritis
Hiroshi Kishikawa, Kenji Nakamura, Keisuke Ojiro, Tadashi Katayama, Kyoko Arahata, Sakiko Takarabe, Aya Sasaki, Soichiro Miura, Yukie Hayashi, Hitomi Hoshi, Takanori Kanai, Jiro Nishida
Scientific Reports.2022;[Epub] CrossRef
Tauroursodeoxycholic Acid Inhibits Nuclear Factor Kappa B Signaling in Gastric Epithelial Cells and Ameliorates Gastric Mucosal Damage in Mice
Su Hwan Kim, Ji Won Kim, Seong-Joon Koh, Sang Gyun Kim, Jeong Mo Bae, Jung Ho Kim, Jeong Hwan Park, Mee Soo Chang, Kee Don Choi, Hyoun Woo Kang, Byeong Gwan Kim, Kook Lae Lee
The Korean Journal of Gastroenterology.2022; 79(4): 161. CrossRef
Serum pepsinogen: A potential non-invasive screening method for moderate and severe atrophic gastritis among an asian population
Cong Long Nguyen, Tran Tien Dao, Thi-Thuy Ngan Phi, The Phuong Nguyen, Van Tuyen Pham, Truong Khanh Vu
Annals of Medicine and Surgery.2022; 78: 103844. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Current status of the gastric cancer screening program in Korea
Young-Il Kim, Il Ju Choi
Journal of the Korean Medical Association.2022; 65(5): 250. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Current Evidence for a Paradigm Shift in Gastric Cancer Prevention From Endoscopic Screening toHelicobacter pyloriEradication in Korea
Young-Il Kim, Il Ju Choi
Journal of Gastric Cancer.2022; 22(3): 169. CrossRef
Need for improvement in the evaluation of pre‐malignant upper gastro‐intestinal lesions in India: Results of a nationwide survey
Deepak Madhu, Veeraraghavan Krishnamurthy, Thirumoorthi Natarajan, Sundeep Lakhtakia
Journal of Gastroenterology and Hepatology.2022; 37(11): 2113. CrossRef
Usefulness of the Kyoto Classification Score for Prediction of Current Helicobacter pylori Infection
Heejun Kang, Chul-Hyun Lim, Sukil Kim, Arum Choi, Jung-Hwan Oh
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2022; 22(4): 281. CrossRef
The simplified Kyoto classification score is consistent with the ABC method of classification as a grading system for endoscopic gastritis
Toshihiro Nishizawa, Osamu Toyoshima, Ryo Kondo, Kazuma Sekiba, Yosuke Tsuji, Hirotoshi Ebinuma, Hidekazu Suzuki, Chizu Tanikawa, Koichi Matsuda, Kazuhiko Koike
Journal of Clinical Biochemistry and Nutrition.2021; 68(1): 101. CrossRef
Endoscopic grading of gastric atrophy on risk assessment of gastric neoplasia: A systematic review and meta‐analysis
Shiyu Xiao, Yihan Fan, Zhihao Yin, Liya Zhou
Journal of Gastroenterology and Hepatology.2021; 36(1): 55. CrossRef
Gastritis: The clinico-pathological spectrum
Massimo Rugge, Edoardo Savarino, Marta Sbaraglia, Ludovica Bricca, Peter Malfertheiner
Digestive and Liver Disease.2021; 53(10): 1237. CrossRef
Efficacy of Seven-Day Potassium-Competitive Acid Blocker-Based First-LineHelicobacter PyloriEradication Therapy Administered with Bismuth
Ji Yeon Kim, Sun-Young Lee, Hyobin Kim, Jeong Hwan Kim, In-Kyung Sung, Hyung Seok Park
Yonsei Medical Journal.2021; 62(8): 708. CrossRef
Second-Line Bismuth-Containing Quadruple Therapy for Helicobacterpylori Infection: A 12-Year Study of Annual Eradication Rates
Kiwon Shin, Min-Jae Cho, Jung-Hwan Oh, Chul-Hyun Lim
Journal of Clinical Medicine.2021; 10(15): 3273. CrossRef
Predictive Significance of Promoter DNA Methylation of Cysteine Dioxygenase Type 1 (CDO1) in Metachronous Gastric Cancer
Yo Kubota, Satoshi Tanabe, Mizutomo Azuma, Kazue Horio, Yoshiki Fujiyama, Takafumi Soeno, Yasuaki Furue, Takuya Wada, Akinori Watanabe, Kenji Ishido, Chikatoshi Katada, Keishi Yamashita, Wasaburo Koizumi, Chika Kusano
Journal of Gastric Cancer.2021; 21(4): 379. CrossRef
Gastrointestinal Microbiota Changes in Patients With Gastric Precancerous Lesions
Dehua Liu, Si Chen, Yawen Gou, Wenyong Yu, Hangcheng Zhou, Rutong Zhang, Jinghao Wang, Fei Ye, Yingling Liu, Baolin Sun, Kaiguang Zhang
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef
Use of endoscopic assessment of gastric atrophy for gastric cancer risk stratification to reduce the need for gastric mapping
Duc Trong Quach, Toru Hiyama, Huy Minh Le, Trung Sao Nguyen, Takuji Gotoda
Scandinavian Journal of Gastroenterology.2020; 55(4): 402. CrossRef
Influence of hypergastrinemia secondary to long-term proton pump inhibitor treatment on ECL cell tumorigenesis in human gastric mucosa
Atsushi Tatsuguchi, Shintaro Hoshino, Noriyuki Kawami, Katya Gudis, Tsutomu Nomura, Akira Shimizu, Katsuhiko Iwakiri
Pathology - Research and Practice.2020; 216(10): 153113. CrossRef
Chronic atrophic gastritis detection with a convolutional neural network considering stomach regions
Misaki Kanai, Ren Togo, Takahiro Ogawa, Miki Haseyama
World Journal of Gastroenterology.2020; 26(25): 3650. CrossRef
Naiv Helicobacter pylori pozitif ve negatif hastaların klinik, demografik ve endoskopik karakteristikleri: Retrospektif analiz
Muhammet AYDIN
Endoskopi Gastrointestinal.2020; 28(2): 39. CrossRef
Gastrointestinal Microbiota Changes in Patients With Gastric Precancerous Lesions
Dehua Liu, Si Chen, Yawen Gou, Wenyong Yu, Hangcheng Zhou, Rutong Zhang, Jinghao Wang, Fei Ye, Yingling Liu, Baolin Sun, Kaiguang Zhang
SSRN Electronic Journal .2020;[Epub] CrossRef

15,217 View
632 Download
40 Web of Science
41 Crossref

Original Article

Immunohistochemical Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Cancer Tissue versus Noncancer Tissue: Hee Jae Jung, Su Jin Hong, Shin Hee Kim; Clin Endosc 2019;52(5):464-471. Published online May 22, 2019; DOI: https://doi.org/10.5946/ce.2018.181

Abstract PDF PubReader ePub

Background
/Aims: Epithelial-mesenchymal transition (EMT) is a developmental process, wherein the epithelial cells show reduced intercellular adhesions and acquire migratory fibroblastic properties. EMT is associated with downregulation in epithelial marker expression, abnormal translocation of E-cadherin, and upregulation in mesenchymal marker expression. Here, we investigated the immunohistochemical (IHC) expression of EMT markers in early gastric cancer (EGC) between cancer and noncancer tissues.
Methods
Tissue samples were prospectively obtained from 19 patients with EGC that underwent endoscopic submucosal dissection (ESD). We compared the expression level of transforming growth factor (TGF)-β, vascular endothelial growth factor (VEGF), E-cadherin, α-smooth muscle actin (α-SMA), and vimentin between cancer and noncancer tissues using IHC. Among the 19 patients, 15 patients had follow-up biopsy at 3 months after ESD for EGC.
Results
Cancer tissues presented higher values of EMT mesenchymal markers (α-SMA/vimentin/TGF-β/VEGF) than the noncancerous tissues (p<0.05) that were significantly low after ESD (p<0.05). No significant correlation was reported for tumor location and initial Helicobacter pylori infection.
Conclusions
The mesenchymal expression of EMT markers was higher in the cancerous tissues than in the noncancer tissues.

Citations

Citations to this article as recorded by

Exploring the role of LINC-ROR in epithelial-mesenchymal transition and its correlation with CD44 and TWIST1 in gastric cancer progression
Reihaneh Alsadat Mahmoudian, Fatemeh Fardi Golyan, Mohammad Mahdi Forghanifard, Mehran Gholamin, Atena Mansouri, Hamid Tanzadehpanah, Mohammad Reza Abbaszadegan
Human Gene.2025; 44: 201394. CrossRef
Gastric Carcinoma with low ROR alpha, low E- Cadherin and High LAPTM4B Immunohistochemical Profile; is associated with unfavorable prognosis in Egyptian patients
Shereen Nagib El Mashad, Mona Abd El Halim Kandil, Taysseer Abd El-Hamid Talab, Abd El Naby Saied Abd El Naby, Mervat Mahmoud Sultan, Ahmed Sohaib, Aiat Shaban Hemida
Journal of Immunoassay and Immunochemistry.2024; 45(1): 50. CrossRef
Hematological, histomorphological, and immunohistochemical diagnosis of bilateral testicular Sertoli cell tumor in a Mongrel dog: a case history
Samson Eneojo Abalaka, Zakariya Audu
Comparative Clinical Pathology.2024; 33(4): 511. CrossRef
MiR-522-3p Targets Transcription Factor 4 to Overcome Cisplatin Resistance of Gastric Cells
Guofeng Ma, Wen Xue, Jie Ni, Ran Tao, Xiangya Ding
Journal of Oncology.2022; 2022: 1. CrossRef
Investigating Helicobacter pylori-related pyloric hypomotility: functional, histological, and molecular alterations
Aya Aly Ashraf, Sarah Mahmoud Gamal, Hend Ashour, Basma Emad Aboulhoda, Laila Ahmed Rashed, Inas Anas Harb, Gaber Hassan Abdelfattah, Eman Ahmed El-Seidi, Heba Mohamed Shawky
American Journal of Physiology-Gastrointestinal and Liver Physiology.2021; 321(5): G461. CrossRef

6,380 View
163 Download
5 Web of Science
5 Crossref

Focused Review Series: Endoscopic Submucosal Dissection for Undifferentiated-Type Early Gastric Cancer

Is Radical Surgery Necessary for All Patients Diagnosed as Having Non-Curative Endoscopic Submucosal Dissection?: Si Hyung Lee, Byung Sam Park; Clin Endosc 2019;52(1):21-29. Published online January 30, 2019; DOI: https://doi.org/10.5946/ce.2019.014

Abstract PDF PubReader ePub

If a lesion does not meet the expanded indication criteria for treatment with endoscopic therapy for early gastric cancer or does not have a positive resection margin, it is regarded as suitable for non-curative resection. Non-curative resection is closely related to the risk of local recurrence, lymph node metastasis, and poor prognosis. If the result is confirmed as non-curative resection, additional treatment should be considered depending on the risks of residual tumor, local recurrence, and lymph node metastasis. As lymphatic invasion is the most important risk factor of recurrence and poor prognosis, surgical treatment should be considered if lymphatic invasion is present. If patients are not suitable for additional surgery owing to old age or coexisting severe disease, close surveillance can be an alternative treatment option.

Citations

Citations to this article as recorded by

Risk Factors and Clinical Outcomes of Non-Curative Resection in Patients with Early Gastric Cancer Treated with Endoscopic Submucosal Dissection: A Retrospective Multicenter Study in Korea
Si Hyung Lee, Min Cheol Kim, Seong Woo Jeon, Kang Nyeong Lee, Jong Jae Park, Su Jin Hong
Clinical Endoscopy.2020; 53(2): 196. CrossRef

6,890 View
106 Download
1 Web of Science
1 Crossref

Focused Review Series: Current Status of Image-Enhanced Endoscopy (IEE)

Linked Color Imaging and Blue Laser Imaging for Upper Gastrointestinal Screening: Hiroyuki Osawa, Yoshimasa Miura, Takahito Takezawa, Yuji Ino, Tsevelnorov Khurelbaatar, Yuichi Sagara, Alan Kawarai Lefor, Hironori Yamamoto; Clin Endosc 2018;51(6):513-526. Published online November 2, 2018; DOI: https://doi.org/10.5946/ce.2018.132

Abstract PDF PubReader ePub

White light imaging (WLI) may not reveal early upper gastrointestinal cancers. Linked color imaging (LCI) produces bright images in the distant view and is performed for the same screening indications as WLI. LCI and blue laser imaging (BLI) provide excellent visibility of gastric cancers in high color contrast with respect to the surrounding tissue. The characteristic purple and green color of metaplasias on LCI and BLI, respectively, serve to increase the contrast while visualizing gastric cancers regardless of a history of Helicobacter pylori eradication.
LCI facilitates color-based recognition of early gastric cancers of all morphological types, including flat lesions or those in an H. pylori-negative normal background mucosa as well as the diagnosis of inflamed mucosae including erosions. LCI reveals changes in mucosal color before the appearance of morphological changes in various gastric lesions. BLI is superior to LCI in the detection of early esophageal cancers and abnormal findings of microstructure and microvasculature in close-up views of upper gastrointestinal cancers. Excellent images can also be obtained with transnasal endoscopy. Using a combination of these modalities allows one to obtain images useful for establishing a diagnosis. It is important to observe esophageal cancers (brown) using BLI and gastric cancers (orange) surrounded by intestinal metaplasia (purple) and duodenal cancers (orange) by LCI.

Citations

Citations to this article as recorded by

Linked color imaging and upper gastrointestinal neoplasia
Shoko Ono, Masaki Inoue, Masayuki Higashino, Shuhei Hayasaka, Shugo Tanaka, Hiroki Egami, Naoya Sakamoto
Digestive Endoscopy.2025; 37(4): 352. CrossRef
Characteristics of Superficial Gastric Neoplasms Detected Not by White Light Imaging but by Linked Color Imaging
Minoru Yamaoka, Hiroyuki Imaeda, Kazuya Miyaguchi, Hisashi Matsumoto, Rie Shiomi, Hideki Ohgo, Nobutaka Hirooka, Yoshikazu Tsuzuki, Hidetomo Nakamoto
JGH Open.2025;[Epub] CrossRef
Higher detectability of gastric cancer after Helicobacter pylori eradication in texture and color enhancement imaging mode 2 in screening endoscopy
Yuichiro Kemmoto, Shun‐ichiro Ozawa, Ryota Sueki, Keiichi Furuya, Daimon Shirose, Satoshi Wakao, Kuniaki Shindo, Atsushi Nagata, Tadashi Sato
DEN Open.2024;[Epub] CrossRef
Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy
Boonyaorn Chatrangsun, Natsuda Aumpan, Bubpha Pornthisarn, Soonthorn Chonprasertsuk, Sith Siramolpiwat, Patommatat Bhanthumkomol, Pongjarat Nunanan, Navapan Issariyakulkarn, Varocha Mahachai, Yoshio Yamaoka, Ratha-korn Vilaichone
BMC Gastroenterology.2024;[Epub] CrossRef
Linked Color Imaging of Barrett’s Esophageal Adenocarcinoma: Effects on Visibility
Masahiro Saito, Tomoyuki Koike, Yuki Ohara, Yohei Ogata, Takeshi Kanno, Xiaoyi Jin, Waku Hatta, Kaname Uno, Naoki Asano, Akira Imatani, Atsushi Masamune
Gastroenterology Insights.2024; 15(1): 145. CrossRef
A Case of Duodenal Adenocarcinoma Effectively Highlighted by Linked Color Imaging and Confirmed by Histopathology
Kimitoshi Kubo, Xinhan Zhang, Ikko Tanaka, Noriko Kimura
Cureus.2024;[Epub] CrossRef
Surveillance esophagogastroduodenoscopy using linked color imaging and narrow‐band imaging: A multicenter randomized controlled trial
Marina Kubo, Shoko Ono, Osamu Dohi, Hayato Fukui, Takuto Hikichi, Tsunetaka Kato, Momoko Tsuda, Mio Matsumoto, Sosuke Kato, Rieko Mukai, Nobuaki Yagi, Ryo Takagi, Naoya Sakamoto, Mototsugu Kato
Journal of Gastroenterology and Hepatology.2024; 39(6): 1065. CrossRef
The Diagnostic Performance of Linked Color Imaging Compared to White Light Imaging in Endoscopic Diagnosis of Helicobacter pylori Infection: A Systematic Review and Meta-Analysis
Jae Gon Lee, In Kyung Yoo, Abdullah Ozgur Yeniova, Sang Pyo Lee
Gut and Liver.2024; 18(3): 444. CrossRef
Diagnostic performance of blue laser imaging for early detection of gastric cancer: A systematic review and meta-analysis
Mohammed Rifat Shaik, Andrew Canakis, Nishat Anjum Shaik, Shivanand Bomman, Dushyant Singh Dahiya, Emily Gorman, Mohammad Bilal, Saurabh Chandan
Indian Journal of Gastroenterology.2024; 43(5): 976. CrossRef
Cromoendoscopia virtual utilizando BLI en el diagnóstico endoscópico de esófago de Barrett neoplásico y no neoplásico
Juan Carlos González
Revista GEN.2024; 77(4): 140. CrossRef
Primary tracheal schwannoma: Bronchoscopic management of a rare tracheal tumour
Krizelle Acibal, Belgundi Preeti Vidyasagar, Harikishan Gonuguntla
Respirology Case Reports.2024;[Epub] CrossRef
Diagnostic accuracy of linked color imaging and white light imaging for early gastric cancer and gastrointestinal metaplasia: a systematic review and meta-analysis
Hui Duan, Xinxu Zhou, Qian Li, Liu Liu, Qiong Wang, Kaiwen Wu, Lin Jiang, Xiaobin Sun
Frontiers in Oncology.2024;[Epub] CrossRef
Current status and future perspective of linked color imaging for gastric cancer screening: a literature review
Kazuo Yashima, Takumi Onoyama, Hiroki Kurumi, Yohei Takeda, Akira Yoshida, Koichiro Kawaguchi, Naoyuki Yamaguchi, Hajime Isomoto
Journal of Gastroenterology.2023; 58(1): 1. CrossRef
Improvement of detection sensitivity of upper gastrointestinal epithelial neoplasia in linked color imaging based on data of eye tracking
Masayuki Higashino, Shoko Ono, Shogo Matsumoto, Marina Kubo, Naohiro Yasuura, Shuhei Hayasaka, Ikko Tanaka, Yoshihiko Shimoda, Yusuke Nishimura, Masayoshi Ono, Keiko Yamamoto, Yuji Ono, Naoya Sakamoto
Journal of Gastroenterology and Hepatology.2023; 38(5): 710. CrossRef
Linked Color Imaging for Stomach
Eiji Umegaki, Hiraku Misawa, Osamu Handa, Hiroshi Matsumoto, Akiko Shiotani
Diagnostics.2023; 13(3): 467. CrossRef
Impact of linked color imaging and blue laser imaging on the diagnosis of esophageal squamous cell carcinoma in iodine unstained areas
Masato Tsunoda, Yoshimasa Miura, Hiroyuki Osawa, Manabu Nagayama, Yuka Kagaya, Yohei Funayama, Takuma Kobayashi, Mami Togashi, Hiroki Hayashi, Yuji Hiraoka, Yoshie Nomoto, Chihiro Iwashita, Yuji Ino, Haruo Takahashi, Hisashi Fukuda, Alan Kawarai Lefor, Hi
The Kaohsiung Journal of Medical Sciences.2023; 39(5): 533. CrossRef
Advances in Endoscopic Diagnosis of Early Gastric Cancer
真徐
Advances in Clinical Medicine.2023; 13(04): 6577. CrossRef
Helicobacter pylori Infection: Conventional and Molecular Strategies for Bacterial Diagnosis and Antibiotic Resistance Testing
Reza Ranjbar, Amir Ebrahimi, Amirhossein Sahebkar
Current Pharmaceutical Biotechnology.2023; 24(5): 647. CrossRef
Linked color imaging versus conventional white light colonoscopy for the detection of colorectal polyps
Jun Watanabe, Takeshi Kanno, Eiichi Kakehi, Kazuma Rifu, Takehiro Kagaya, Kazuhiko Kotani, Yuki Kataoka
Cochrane Database of Systematic Reviews.2023;[Epub] CrossRef
Role of linked color imaging for upper gastrointestinal disease: present and future
Sang Pyo Lee
Clinical Endoscopy.2023; 56(5): 546. CrossRef
Landscape of Innovative Methods for Early Diagnosis of Gastric Cancer: A Systematic Review
Alexandra Orășeanu, Mihaela Cristina Brisc, Octavian Adrian Maghiar, Horia Popa, Ciprian Mihai Brisc, Sabina Florina Șolea, Teodor Andrei Maghiar, Ciprian Brisc
Diagnostics.2023; 13(24): 3608. CrossRef
Diagnostic ability of linked color imaging in ultraslim endoscopy to identify neoplastic lesions in the upper gastrointestinal tract
Ken Haruma, Mototsugu Kato, Kenro Kawada, Takahisa Murao, Shoko Ono, Mitsuhiko Suehiro, Shinichiro Hori, Fumisato Sasaki, Tomoyuki Koike, Shinji Kitamura, Osamu Dohi, Hiromitsu Kanzaki, Nobuaki Yagi, Keiichi Hashiguchi, Shiro Oka, Kazuhiro Katada, Ryo Shi
Endoscopy International Open.2022; 10(01): E88. CrossRef
Incidence of Infection among Subjects with Helicobacter pylori Seroconversion
Young Jung Kim, Sun-Young Lee, Jeong Hwan Kim, In-Kyung Sung, Hyung Seok Park
Clinical Endoscopy.2022; 55(1): 67. CrossRef
Linked color imaging effectively detects the endoscopic atrophic border in transnasal endoscopy
Yusuke Kawai, Mitsushige Sugimoto, Mariko Hamada, Eri Iwata, Ryota Niikura, Naoyoshi Nagata, Masakatsu Fukuzawa, Takao Itoi, Takashi Kawai
Journal of Clinical Biochemistry and Nutrition.2022; 70(3): 290. CrossRef
Linked color imaging improves identification of early gastric cancer lesions by expert and non-expert endoscopists
Kiki Fockens, Jeroen de Groof, Joost van der Putten, Tsevelnorov Khurelbaatar, Hisashi Fukuda, Takahito Takezawa, Yoshimasa Miura, Hiroyuki Osawa, Hironori Yamamoto, Jacques Bergman
Surgical Endoscopy.2022; 36(11): 8316. CrossRef
Improved detection of early gastric cancer with linked color imaging using an ultrathin endoscope: a video-based analysis
Tsevelnorov Khurelbaatar, Yoshimasa Miura, Hiroyuki Osawa, Yuji Ino, Takahito Takezawa, Chihiro Iwashita, Yoshie Nomoto, Masato Tsunoda, Takashi Ueno, Haruo Takahashi, Manabu Nagayama, Hisashi Fukuda, Alan Kawarai Lefor, Hironori Yamamoto
Endoscopy International Open.2022; 10(05): E644. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Diagnostic accuracy of linked colour imaging versus white light imaging for early gastric cancers: a prospective, multicentre, randomized controlled trial study
Min Min, Xiaotian Sun, Jianying Bai, Qinsheng Zhang, Xiaocui Yang, Qiang Guo, Rong Wang, Bangmao Wang, Zhiwu Lv, Jie Pan, Chunmeng Jiang, Duanmin Hu, Bing Nong, Enqiang Linghu, Yan Liu
Annals of Medicine.2022; 54(1): 3305. CrossRef
Using texture and colour enhancement imaging to evaluate gastrointestinal diseases in clinical practice: a review
Mitsushige Sugimoto, Yohei Koyama, Takao Itoi, Takashi Kawai
Annals of Medicine.2022; 54(1): 3314. CrossRef
Current Endoscopy Training in Korea and Future Aspects
Young-Eun Joo
The Korean Journal of Gastroenterology.2022; 80(5): 207. CrossRef
A Method for Local Contrast Enhancement of Endoscopic Images Based on Color Tensor Transformation into a Matrix of Color Vectors’ Modules Using a Sliding Window
Roumen Kountchev, Alexander Bekiarski, Rumen Mironov, Snezhana Pleshkova
Symmetry.2022; 14(12): 2582. CrossRef
A rare case of Helicobacter pylori-uninfected intramucosal poorly differentiated adenocarcinoma that occurred in the gastric fornix
Yukinari Yoshida, Hiroaki Takahashi, Tomoyuki Ohuchi, Satoshi Okahara, Yoshifumi Ishii, Toshinao Takenouchi, Toshiyuki Kubo, Takefumi Kikuchi, Hiroaki Mita, Yasuyo Adachi, Norikazu Iwata, Masahiro Nakamura, Yasushi Adachi, Yasuo Kato, Takao Endo
Clinical Journal of Gastroenterology.2021; 14(1): 63. CrossRef
Detection of early stage gastric cancers in screening laser endoscopy using linked color imaging for patients with atrophic gastritis
Minoru Yamaoka, Hiroyuki Imaeda, Kazuya Miyaguchi, Keigo Ashitani, Yoshikazu Tsuzuki, Hideki Ohgo, Hiromitsu Soma, Nobutaka Hirooka, Hidetomo Nakamoto
Journal of Gastroenterology and Hepatology.2021; 36(6): 1642. CrossRef
Linked Color Imaging Demonstrates Characteristic Findings in Semi-Pedunculated Gastric Adenocarcinoma in Helicobacter pylori-Negative Normal Mucosa
Yuji Hiraoka, Yoshimasa Miura, Hiroyuki Osawa, Mio Sakaguchi, Masato Tsunoda, Alan Kawarai Lefor, Hironori Yamamoto
Clinical Endoscopy.2021; 54(1): 136. CrossRef
The role of computer-assisted systems for upper-endoscopy quality monitoring and assessment of gastric lesions
Daniela Cornelia Lazăr, Mihaela Flavia Avram, Alexandra Corina Faur, Ioan Romoşan, Adrian Goldiş
Gastroenterology Report.2021; 9(3): 185. CrossRef
A prospective randomized tandem gastroscopy pilot study of linked color imaging versus white light imaging for detection of upper gastrointestinal lesions
Clement Chun Ho Wu, Vikneswaran Namasivayam, James Weiquan Li, Chris JL Khor, Kwong Ming Fock, Ngai Moh Law, Lai Mun Wang, Tiing Leong Ang
Journal of Gastroenterology and Hepatology.2021; 36(9): 2562. CrossRef
What Is New in Helicobacter pylori Diagnosis. An Overview
Maria Pina Dore, Giovanni Mario Pes
Journal of Clinical Medicine.2021; 10(10): 2091. CrossRef
Inter‐observer variability of experts and trainees for the diagnosis of reflux esophagitis: Comparison of linked color imaging, blue laser imaging, and white light imaging
Sang Pyo Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Eun Suk Jung
Journal of Digestive Diseases.2021; 22(7): 425. CrossRef
Appropriate Color Enhancement Settings for Blue Laser Imaging Facilitates the Diagnosis of Early Gastric Cancer with High Color Contrast
Yuji Hiraoka, Yoshimasa Miura, Hiroyuki Osawa, Yoshie Nomoto, Haruo Takahashi, Masato Tsunoda, Manabu Nagayama, Takashi Ueno, Alan Kawarai Lefor, Hironori Yamamoto
Journal of Gastric Cancer.2021; 21(2): 142. CrossRef
Application of linked color imaging in the diagnosis of early gastrointestinal neoplasms and precancerous lesions: a review
Shanshan Wang, Lei Shen, Hesheng Luo
Therapeutic Advances in Gastroenterology.2021;[Epub] CrossRef
Association between abdominal symptoms and gastric body redness in Linked Color Imaging in patients without Helicobacter pylori infection
Tsutomu Takeda, Daisuke Asaoka, Hisanori Utsunomiya, Shotaro Oki, Nobuyuki Suzuki, Daiki Abe, Atsushi Ikeda, Noboru Yatagai, Yoichi Akazawa, Kohei Matsumoto, Kumiko Ueda, Hiroya Ueyama, Kenshi Matsumoto, Mariko Hojo, Shuko Nojiri, Akihito Nagahara
Progress of Digestive Endoscopy.2021; 98(1): 24. CrossRef
Diagnosis of Helicobacter pylori Infection and Recent Advances
Hang Yang, Bing Hu
Diagnostics.2021; 11(8): 1305. CrossRef
Clinical Applications of Linked Color Imaging and Blue Laser/Light Imaging in the Screening, Diagnosis, and Treatment of Superficial Colorectal Tumors
Taku Sakamoto, Hourin Cho, Yutaka Saito
Clinical Endoscopy.2021; 54(4): 488. CrossRef
Application of Current Image-Enhanced Endoscopy in Gastric Diseases
Wansik Lee
Clinical Endoscopy.2021; 54(4): 477. CrossRef
Linked-color Imaging May Help Improve the Visibility of Superficial Barrett's Esophageal Adenocarcinoma by Increasing the Color Difference
Masahiro Saito, Tomoyuki Koike, Yuki Ohara, Kenichiro Nakagawa, Takeshi Kanno, Xiaoyi Jin, Waku Hatta, Kaname Uno, Naoki Asano, Akira Imatani, Atsushi Masamune
Internal Medicine.2021; 60(21): 3351. CrossRef
Potential of automatic diagnosis system with linked color imaging for diagnosis of Helicobacter pylori infection
Takeshi Yasuda, Tomoyuki Hiroyasu, Satoru Hiwa, Yuto Okada, Sadanari Hayashi, Yuki Nakahata, Yuriko Yasuda, Tatsushi Omatsu, Akihiro Obora, Takao Kojima, Hiroshi Ichikawa, Nobuaki Yagi
Digestive Endoscopy.2020; 32(3): 373. CrossRef
Linked Color Imaging of Eosinophilic Esophagitis
Yasuhiko Abe, Yu Sasaki, Takashi Kon, Yoshiyuki Ueno
Internal Medicine.2020; 59(12): 1573. CrossRef
Optical enhancement imaging versus acetic acid for detecting gastric intestinal metaplasia: A randomized, comparative trial
Rui Ji, Jun Liu, Ming-Ming Zhang, Yue-Yue Li, Xiu-Li Zuo, Xiao Wang, Yan-Qing Li
Digestive and Liver Disease.2020; 52(6): 651. CrossRef
The Efficacy of Linked Color Imaging in the Endoscopic Diagnosis of Barrett’s Esophagus and Esophageal Adenocarcinoma
Mamoru Tokunaga, Tomoaki Matsumura, Kentaro Ishikawa, Tatsuya Kaneko, Hirotaka Oura, Tsubasa Ishikawa, Ariki Nagashima, Wataru Shiratori, Kenichiro Okimoto, Naoki Akizue, Daisuke Maruoka, Yuki Ohta, Keiko Saito, Tomoo Nakagawa, Tetsuhiro Chiba, Makoto Ara
Gastroenterology Research and Practice.2020; 2020: 1. CrossRef
Linked color imaging can improve the visibility of superficial non-ampullary duodenal epithelial tumors
Kenichiro Okimoto, Daisuke Maruoka, Tomoaki Matsumura, Mamoru Tokunaga, Tatsuya Kaneko, Hirotaka Oura, Naoki Akizue, Yuki Ohta, Keiko Saito, Makoto Arai, Jun Kato, Naoya Kato
Scientific Reports.2020;[Epub] CrossRef
Endoscopy training in Korea
Joon Sung Kim, Byung-Wook Kim
The Korean Journal of Internal Medicine.2019; 34(2): 237. CrossRef
Review: Diagnosis of Helicobacter pylori infection
Athanasios Makristathis, Alexander M. Hirschl, Francis Mégraud, Emilie Bessède
Helicobacter.2019;[Epub] CrossRef
New Diagnostic Approach for Esophageal Squamous Cell Neoplasms Using Linked Color Imaging and Blue Laser Imaging Combined with Iodine Staining
Masato Tsunoda, Yoshimasa Miura, Hiroyuki Osawa, Tsevelnorov Khurelbaatar, Mio Sakaguchi, Hisashi Fukuda, Alan Kawarai Lefor, Hironori Yamamoto
Clinical Endoscopy.2019; 52(5): 497. CrossRef
Linked color imaging for the detection of early gastrointestinal neoplasms
Satoshi Shinozaki, Hiroyuki Osawa, Yoshikazu Hayashi, Alan Kawarai Lefor, Hironori Yamamoto
Therapeutic Advances in Gastroenterology.2019;[Epub] CrossRef
Linked Color Imaging Highlights Flat Early Gastric Cancer
Kimitoshi Kubo, Noriko Kimura, Soichiro Matsuda, Momoko Tsuda, Mototsugu Kato
Case Reports in Gastroenterology.2019; 13(3): 532. CrossRef

11,569 View
575 Download
56 Web of Science
55 Crossref

Case Reports

A Rare Case of Lymph Node Metastasis from Early Gastric Cancer: Takaaki Yoshikawa, Yoshio Kadokawa, Masaya Ohana, Akihisa Fukuda, Hiroshi Seno; Clin Endosc 2019;52(4):369-372. Published online October 5, 2018; DOI: https://doi.org/10.5946/ce.2018.130

Abstract PDF PubReader ePub

Gastric cancers that fulfill the Japanese criteria for curative endoscopic resection show a low risk of lymph node (LN) metastasis. Here, we report a case of LN metastasis from early gastric cancer that fulfilled the curative criteria. A 74-year-old Japanese woman was referred to our hospital for treatment of early gastric cancer identified at the site of a hyperplastic polyp that had been diagnosed 10 years prior to presentation. Contrast-enhanced computed tomography did not show any lymphadenopathy and laparoscopy-assisted distal gastrectomy was performed. Histopathological examination revealed a predominantly moderately differentiated adenocarcinoma that measured 15 mm in size and was confined to the mucosa. However, a single metastatic regional LN was observed. A few cancer cells showed positive staining for alpha-fetoprotein. It should be noted that early gastric cancer can be accompanied by LN metastasis even if it fulfills the criteria for curative endoscopic resection.

Citations

Citations to this article as recorded by

Alpha-fetoprotein-producing intramucosal gastric cancer found during examination of metastatic lymph nodes
Tomoya Sano, Takahiro Toyokawa, Mami Yoshii, Yuichiro Miki, Tatsuro Tamura, Shigeru Lee, Kiyoshi Maeda
Clinical Journal of Gastroenterology.2025; 18(1): 57. CrossRef

5,400 View
132 Download
1 Web of Science
1 Crossref

Blue Laser Imaging with a Small-Caliber Endoscope Facilitates Detection of Early Gastric Cancer: Haruo Takahashi, Yoshimasa Miura, Hiroyuki Osawa, Takahito Takezawa, Yuji Ino, Masahiro Okada, Alan Kawarai Lefor, Hironori Yamamoto; Clin Endosc 2019;52(3):273-277. Published online August 14, 2018; DOI: https://doi.org/10.5946/ce.2018.100

Abstract PDF PubReader ePub

Conventional endoscopy often misses early gastric cancers with minimal red discoloration because they cannot be distinguished from inflamed mucosa. We treated a patient with a small early gastric cancer that was difficult to diagnose using conventional endoscopy. Conventional endoscopy using a small-caliber endoscope showed only subtle red discoloration of the gastric mucosa. However, blue laser imaging showed a clearly discolored area measuring 10 mm in diameter around the red lesion, which was distinct from the surrounding inflamed mucosa. Irregular vessels on the tumor surface (suspicious for early gastric cancer) were observed even with small-caliber endoscopy. Biopsy revealed a well-moderately differentiated tubular adenocarcinoma, and endoscopic submucosal dissection was performed. Histopathological examination of the specimen confirmed well-moderately differentiated adenocarcinoma localized to the mucosa with slight depression compared to the surrounding mucosa, consistent with the endoscopic findings. This small early gastric cancer became clearly visible with blue laser imaging using small-caliber endoscopy.

Citations

Citations to this article as recorded by

Diagnostic performance of blue laser imaging for early detection of gastric cancer: A systematic review and meta-analysis
Mohammed Rifat Shaik, Andrew Canakis, Nishat Anjum Shaik, Shivanand Bomman, Dushyant Singh Dahiya, Emily Gorman, Mohammad Bilal, Saurabh Chandan
Indian Journal of Gastroenterology.2024; 43(5): 976. CrossRef
Improved detection of early gastric cancer with linked color imaging using an ultrathin endoscope: a video-based analysis
Tsevelnorov Khurelbaatar, Yoshimasa Miura, Hiroyuki Osawa, Yuji Ino, Takahito Takezawa, Chihiro Iwashita, Yoshie Nomoto, Masato Tsunoda, Takashi Ueno, Haruo Takahashi, Manabu Nagayama, Hisashi Fukuda, Alan Kawarai Lefor, Hironori Yamamoto
Endoscopy International Open.2022; 10(05): E644. CrossRef
Current status of the gastric cancer screening program in Korea
Young-Il Kim, Il Ju Choi
Journal of the Korean Medical Association.2022; 65(5): 250. CrossRef
Current Evidence for a Paradigm Shift in Gastric Cancer Prevention From Endoscopic Screening toHelicobacter pyloriEradication in Korea
Young-Il Kim, Il Ju Choi
Journal of Gastric Cancer.2022; 22(3): 169. CrossRef
Clinical Features of False-Negative Early Gastric Cancers: A Retrospective Study of Endoscopic Submucosal Dissection Cases
Kohei Oka, Naoto Iwai, Takashi Okuda, Tasuku Hara, Yutaka Inada, Toshifumi Tsuji, Toshiyuki Komaki, Junichi Sakagami, Yuji Naito, Keizo Kagawa, Yoshito Itoh, Fabiana Zingone
Gastroenterology Research and Practice.2021; 2021: 1. CrossRef
Appropriate Color Enhancement Settings for Blue Laser Imaging Facilitates the Diagnosis of Early Gastric Cancer with High Color Contrast
Yuji Hiraoka, Yoshimasa Miura, Hiroyuki Osawa, Yoshie Nomoto, Haruo Takahashi, Masato Tsunoda, Manabu Nagayama, Takashi Ueno, Alan Kawarai Lefor, Hironori Yamamoto
Journal of Gastric Cancer.2021; 21(2): 142. CrossRef
Linked Color Imaging and Blue Laser Imaging for Upper Gastrointestinal Screening
Hiroyuki Osawa, Yoshimasa Miura, Takahito Takezawa, Yuji Ino, Tsevelnorov Khurelbaatar, Yuichi Sagara, Alan Kawarai Lefor, Hironori Yamamoto
Clinical Endoscopy.2018; 51(6): 513. CrossRef

6,430 View
172 Download
9 Web of Science
7 Crossref

Review

Metachronous Gastric Cancer Following Curative Endoscopic Resection of Early Gastric Cancer: Seiichiro Abe, Ichiro Oda, Takeyoshi Minagawa, Masau Sekiguchi, Satoru Nonaka, Haruhisa Suzuki, Shigetaka Yoshinaga, Amit Bhatt, Yutaka Saito; Clin Endosc 2018;51(3):253-259. Published online September 18, 2017; DOI: https://doi.org/10.5946/ce.2017.104

Abstract PDF PubReader ePub

This review article summarizes knowledge about metachronous gastric cancer (MGC) occurring after curative endoscopic resection (ER) of early gastric cancer (EGC), treatment outcomes of patients who developed MGC, and efficacy of Helicobacter pylori eradication to prevent MGC. The incidence of MGC following curative ER increases over time and is higher than in patients undergoing gastrectomy. Increasing age and multifocal EGC are independent risk factors for developing MGC. An MGC following curative ER is usually a small (<20 mm) and differentiated intramucosal cancer. Most MGC lesions are found at an early stage on semiannual or annual surveillance endoscopy and are successfully treated by further ER, with excellent long-term outcomes. Eradication of H. pylori may reduce the risk of MGC following ER of EGC, but further prospective studies with long-term outcomes are required. Surveillance endoscopy following gastric ER should be continued indefinitely, due to the risk of MGC even after successful H. pylori eradication. Risk stratification and tailored endoscopic surveillance schedules need to be developed.

Citations

Citations to this article as recorded by

AGA Clinical Practice Update on Screening and Surveillance in Individuals at Increased Risk for Gastric Cancer in the United States: Expert Review
Shailja C. Shah, Andrew Y. Wang, Michael B. Wallace, Joo Ha Hwang
Gastroenterology.2025; 168(2): 405. CrossRef
Impact of endoscopy intervals on metachronous gastric cancer after endoscopic submucosal dissection: Comparison between 1 year and half‐a‐year
Yuichiro Ozeki, Kingo Hirasawa, Atsushi Sawada, Ryosuke Ikeda, Masafumi Nishio, Takehide Fukuchi, Ryosuke Kobayashi, Chiko Sato, Shin Maeda
Digestive Endoscopy.2024; 36(3): 332. CrossRef
High risk of multiple gastric cancers in Japanese individuals with Lynch syndrome
Nobuhiko Kanaya, Thijs A. van Schaik, Hideki Aoki, Yumiko Sato, Fumitaka Taniguchi, Kunitoshi Shigeyasu, Kokichi Sugano, Kiwamu Akagi, Hideyuki Ishida, Kohji Tanakaya
Annals of Gastroenterological Surgery.2024; 8(6): 1008. CrossRef
Clinical outcomes of ablation of gastric dysplasia with argon plasma coagulation
Mi Jin Oh, Sang Gyun Kim, Jiyoon Kim, Yun Suk Na, Seunghan Lee, Junhee Lee, Bokyung Kim, Hyunsoo Chung, Soo-Jeong Cho, Miquel Vall-llosera Camps
PLOS ONE.2024; 19(7): e0306934. CrossRef
Optimal Surveillance of Metachronous Gastric Lesion after Endoscopic Resection of Early Gastric Cancer
Dong Chan Joo, Gwang Ha Kim
Gut and Liver.2024; 18(5): 781. CrossRef
Latest guideline of endoscopic submucosal dissection of early gastric cancer may not be suitable for Chinese patients: retrospective study findings from two centers
Yu Mei, Jianpeng Gao, Benyan Zhang, Tienan Feng, Wei Wu, Zhenggang Zhu, Zhenglun Zhu
Surgical Endoscopy.2024; 38(11): 6726. CrossRef
Risk assessment of metachronous gastric cancer development using OLGA and OLGIM systems after endoscopic submucosal dissection for early gastric cancer: a long-term follow-up study
Yun Suk Na, Sang Gyun Kim, Soo-Jeong Cho
Gastric Cancer.2023; 26(2): 298. CrossRef
Metachronous lesions after gastric endoscopic submucosal dissection: first assessment of the FAMISH prediction score
Andreia Rei, Raquel Ortigão, Mariana Pais, Luís P. Afonso, Pedro Pimentel-Nunes, Mário Dinis-Ribeiro, Diogo Libânio
Endoscopy.2023; 55(10): 909. CrossRef
Variation in the rate of detection of minute and small early gastric cancers at diagnostic endoscopy may reflect the performance of individual endoscopists
Daisuke Murakami, Masayuki Yamato, Yuji Amano, Takayoshi Nishino, Makoto Arai
BMJ Open Gastroenterology.2023; 10(1): e001143. CrossRef
Decision to perform additional surgery after non-curative endoscopic submucosal dissection for gastric cancer based on the risk of lymph node metastasis: a long-term follow-up study
Seunghan Lee, Sang Gyun Kim, Soo-Jeong Cho
Surgical Endoscopy.2023; 37(10): 7738. CrossRef
Helicobacter pylori Eradication Can Reverse Rho GTPase Expression in Gastric Carcinogenesis
Jue Lie Kim, Sang Gyun Kim, Enerelt Natsagdorj, Hyunsoo Chung, Soo-Jeong Cho
Gut and Liver.2023; 17(5): 741. CrossRef
Risk assessment of metachronous gastric cancer after endoscopic submucosal dissection based on endoscopic intestinal metaplasia
Chino Iizuka, Soichiro Sue, Sho Onodera, Aya Ikeda, Ryosuke Ikeda, Yoshihiro Goda, Kuniyasu Irie, Hiroaki Kaneko, Shin Maeda
JGH Open.2023; 7(11): 783. CrossRef
Second gastric cancer after curative endoscopic resection of differentiated-type early gastric cancer: post-hoc analysis of a single-arm confirmatory trial
Masao Yoshida, Kohei Takizawa, Noriaki Hasuike, Hiroyuki Ono, Narikazu Boku, Tomohiro Kadota, Junki Mizusawa, Ichiro Oda, Naohiro Yoshida, Yusuke Horiuchi, Kingo Hirasawa, Yoshinori Morita, Yoshinobu Yamamoto, Manabu Muto, Masao Yoshida, Kohei Takizawa, H
Gastrointestinal Endoscopy.2022; 95(4): 650. CrossRef
Therapeutic approach to non-curative resection after endoscopic treatment in early gastric cancer
Eun Jeong Gong, Chang Seok Bang
Journal of the Korean Medical Association.2022; 65(5): 284. CrossRef
Assessment of Outcomes From 1-Year Surveillance After Detection of Early Gastric Cancer Among Patients at High Risk in Japan
Yoshinobu Yamamoto, Naohiro Yoshida, Tomonori Yano, Takahiro Horimatsu, Noriya Uedo, Noboru Kawata, Hiromitsu Kanzaki, Shinichiro Hori, Kenshi Yao, Seiichiro Abe, Chikatoshi Katada, Chizu Yokoi, Ken Ohata, Hisashi Doyama, Kenichi Yoshimura, Hideki Ishikaw
JAMA Network Open.2022; 5(8): e2227667. CrossRef
Management of patients with multiple primary сancer in the practice of a modern oncologist. Case report and literature review
D. A. Khlanta, G. P. Gens
Siberian journal of oncology.2022; 21(4): 147. CrossRef
Assigning a different endoscopist for each annual follow-up may contribute to improved gastric cancer detection rates
Shuhei Unno, Kimihiro Igarashi, Hiroaki Saito, Dai Hirasawa, Toru Okuzono, Yukari Tanaka, Masato Nakahori, Tomoki Matsuda
Endoscopy International Open.2022; 10(10): E1333. CrossRef
Statistical proof of Helicobacter pylori eradication in preventing metachronous gastric cancer after endoscopic resection in an East Asian population
Mohsen Karbalaei, Masoud Keikha
World Journal of Gastrointestinal Surgery.2022; 14(8): 867. CrossRef
Follow-up after endoscopic resection for early gastric cancer in 3 French referral centers
Bernadette de Rauglaudre, Mathieu Pioche, Fabrice Caillol, Jean-Philippe Ratone, Anna Pellat, Romain Coriat, Jerôme Rivory, Thomas Lambin, Laetitia Dahan, Marc Giovanini, Maximilien Barret
iGIE.2022; 1(1): 49. CrossRef
Documento de posicionamiento de la AEG, la SEED y la SEAP sobre cribado de cáncer gástrico en poblaciones con baja incidencia
Joaquín Cubiella, Ángeles Pérez Aisa, Miriam Cuatrecasas, Pilar Díez Redondo, Gloria Fernández Esparrach, José Carlos Marín-Gabriel, Leticia Moreira, Henar Núñez, M. Luisa Pardo López, Enrique Rodríguez de Santiago, Pedro Rosón, José Miguel Sanz Anquela,
Gastroenterología y Hepatología.2021; 44(1): 67. CrossRef
Incidence of metachronous cancer after endoscopic submucosal dissection: a comparison between undifferentiated-type and differentiated-type early gastric cancer
Mitsuaki Ishioka, Toshiyuki Yoshio, Yuji Miyamoto, Ken Namikawa, Yoshitaka Tokai, Shoichi Yoshimizu, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki
Gastrointestinal Endoscopy.2021; 93(3): 557. CrossRef
Gastric cancer screening in low incidence populations: Position statement of AEG, SEED and SEAP
Joaquin Cubiella, Ángeles Pérez Aisa, Miriam Cuatrecasas, Pilar Díez Redondo, Gloria Fernández Esparrach, José Carlos Marín-Gabriel, Leticia Moreira, Henar Núñez, M. Luisa Pardo López, Enrique Rodríguez de Santiago, Pedro Rosón, José Miguel Sanz Anquela,
Gastroenterología y Hepatología (English Edition).2021; 44(1): 67. CrossRef
Molecular risk markers related to local tumor recurrence at histological margin-free endoscopically resected early gastric cancers: A pilot study
Ho Suk Kang, Mi Jung Kwon, Premi Haynes, Yan Liang, Yuqi Ren, Hyun Lim, Jae Seung Soh, Nan Young Kim, Hye Kyung Lee
Pathology - Research and Practice.2021; 222: 153434. CrossRef
Characteristics of metachronous gastric neoplasms after curative endoscopic submucosal dissection for early gastric neoplasms
Shan-Shan Xu, Ning-Li Chai, Xiao-Wei Tang, En-Qiang Linghu, Sha-Sha Wang, Bao Li
Chinese Medical Journal.2021; 134(21): 2603. CrossRef
Consenso mexicano sobre detección y tratamiento del cáncer gástrico incipiente
M.E. Icaza-Chávez, M.A. Tanimoto, F.M. Huerta-Iga, J.M. Remes-Troche, R. Carmona-Sánchez, A. Ángeles-Ángeles, F.J. Bosques-Padilla, J.M. Blancas-Valencia, G. Grajales-Figueroa, O.V. Hernández-Mondragón, A.I. Hernández-Guerrero, M.A. Herrera-Servín, F.D. H
Revista de Gastroenterología de México.2020; 85(1): 69. CrossRef
The Mexican consensus on the detection and treatment of early gastric cancer
M.E. Icaza-Chávez, M.A. Tanimoto, F.M. Huerta-Iga, J.M. Remes-Troche, R. Carmona-Sánchez, A. Ángeles-Ángeles, F.J. Bosques-Padilla, J.M. Blancas-Valencia, G. Grajales-Figueroa, O.V. Hernández-Mondragón, A.I. Hernández-Guerrero, M.Á. Herrera-Servín, F.D. H
Revista de Gastroenterología de México (English Edition).2020; 85(1): 69. CrossRef
Long‐term follow up of serum pepsinogens in patients with gastric cancer or dysplasia after Helicobacter pylori eradication
Gitark Noh, Nayoung Kim, Yonghoon Choi, Hye Seung Lee, Young Jae Hwang, Hee Jin Kim, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee
Journal of Gastroenterology and Hepatology.2020; 35(9): 1540. CrossRef
Metachronous Gastric Cancer: Another Hurdle for Successful Endoscopic Treatment for Early Gastric Cancer?
Moon Won Lee, Gwang Ha Kim
Gut and Liver.2020; 14(2): 145. CrossRef
Clinical Outcomes of Metachronous Gastric Cancer after Endoscopic Resection for Early Gastric Cancer
Jue Lie Kim, Sang Gyun Kim, Jung Kim, Jae Yong Park, Hyo-Joon Yang, Hyun Ju Kim, Hyunsoo Chung
Gut and Liver.2020; 14(2): 190. CrossRef
Chemoprevention of gastric cancer development afterHelicobacter pylorieradication therapy in an East Asian population: Meta-analysis
Mitsushige Sugimoto, Masaki Murata, Yoshio Yamaoka
World Journal of Gastroenterology.2020; 26(15): 1820. CrossRef
MULTIFOCAL EARLY GASTRIC CANCER IN A PATIENT WITH ATROPHIC GASTRITIS AND PERNICIOUS ANEMIA
Tommaso Zurleni, Michele Altomare, Giovanni Serio, Filippo Catalano
International Journal of Surgery Case Reports.2020;[Epub] CrossRef
Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
Hyun Ju Kim, Yun Jin Kim, Seung In Seo, Woon Geon Shin, Chan Hyuk Park
Gastrointestinal Endoscopy.2020; 92(3): 613. CrossRef
Gastric cancer prevention strategies: A global perspective
Leonardo Henry Eusebi, Andrea Telese, Giovanni Marasco, Franco Bazzoli, Rocco Maurizio Zagari
Journal of Gastroenterology and Hepatology.2020; 35(9): 1495. CrossRef
Metachronous Gastric Cancer Occurring after Endoscopic Resection of Early Gastric Cancer
Gwang Ha Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2020; 20(4): 295. CrossRef
Somatic alterations and mutational burden are potential predictive factors for metachronous development of early gastric cancer
Kazuhiro Sakuta, Yu Sasaki, Yasuhiko Abe, Hidenori Sato, Masakuni Shoji, Takao Yaoita, Makoto Yagi, Naoko Mizumoto, Yusuke Onozato, Takashi Kon, Ayumi Koseki, Sonoko Sato, Ryoko Murakami, Yuki Miyano, Yoshiyuki Ueno
Scientific Reports.2020;[Epub] CrossRef
Clinicopathologic Characteristics of Patients with Gastric Superficial Neoplasia and Risk Factors for Multiple Lesions after Endoscopic Submucosal Dissection in a Western Country
Gisela Brito-Gonçalves, Diogo Libânio, Pedro Marcos, Inês Pita, Rui Castro, Inês Sá, Mário Dinis-Ribeiro, Pedro Pimentel-Nunes
GE - Portuguese Journal of Gastroenterology.2020; 27(2): 76. CrossRef
Helicobacter pylori status and risks of metachronous recurrence after endoscopic resection of early gastric cancer: a systematic review and meta-analysis
Shiyu Xiao, Sizhu Li, Liya Zhou, Wenjun Jiang, Jinzhe Liu
Journal of Gastroenterology.2019; 54(3): 226. CrossRef
Helicobacter pylori Eradication for Metachronous Gastric Cancer: An Unsuitable Methodology Impeding Broader Clinical Usage
Alexios-Fotios A. Mentis, Efthimios Dardiotis
Frontiers in Oncology.2019;[Epub] CrossRef
Common Locations of Gastric Cancer: Review of Research from the Endoscopic Submucosal Dissection Era
Su Jin Kim, Cheol Woong Choi
Journal of Korean Medical Science.2019;[Epub] CrossRef
UEG Week 2019 Poster Presentations

United European Gastroenterology Journal.2019; 7(S8): 189. CrossRef
Helicobacter pylori Infection following Endoscopic Resection of Early Gastric Cancer
Lan Li, Chaohui Yu
BioMed Research International.2019; 2019: 1. CrossRef
Prophylaxis and early diagnosis of stomach cancer
I. G. Bakulin, S. S. Pirogov, N. V. Bakulina, E. A. Stadnik, N. N. Golubev
Dokazatel'naya gastroenterologiya.2018; 7(2): 44. CrossRef
Linked Color Imaging and Blue Laser Imaging for Upper Gastrointestinal Screening
Hiroyuki Osawa, Yoshimasa Miura, Takahito Takezawa, Yuji Ino, Tsevelnorov Khurelbaatar, Yuichi Sagara, Alan Kawarai Lefor, Hironori Yamamoto
Clinical Endoscopy.2018; 51(6): 513. CrossRef

10,723 View
298 Download
38 Web of Science
43 Crossref

Case Report

A Rare Case of Early Gastric Cancer Combined with Underlying Heterotopic Pancreas: Jung Bin Yoon, Bong Eun Lee, Dae Hwan Kim, Do Youn Park, Hye Kyung Jeon, Dong Hoon Baek, Gwang Ha Kim, Geun Am Song; Clin Endosc 2018;51(2):192-195. Published online August 31, 2017; DOI: https://doi.org/10.5946/ce.2017.055

Abstract PDF PubReader ePub

Heterotopic pancreas in the stomach is usually asymptomatic and benign. Here, we presented a rare case of an early gastric cancer overlying a heterotopic pancreas. A 48-year-old woman underwent esophagogastroduodenoscopy, which revealed a subepithelial mass measuring 2.0×1.5 cm on the gastric antrum with a 1-cm erosive erythematous discoloration on the surface. A biopsy specimen showed moderately differentiated tubular adenocarcinoma. Endosonography showed a heterogeneous hypoechoic mass measuring 1.3×0.6 cm, with indistinct margins in the second and third layers of the gastric wall; anechoic tubular structures within the mass were suggestive of heterotopic pancreas. Distal gastrectomy was performed, which confirmed an early gastric cancer confined to the mucosa, and a separate underlying heterotopic pancreas. Although heterotopic pancreas is most likely benign, careful endoscopic observation of the mucosal surface is necessary to avoid overlooking a coincident early gastric cancer.

Citations

Citations to this article as recorded by

Duodenal Heterotopic Pancreas with a Large Retention Cyst: A Case Report and Literature Review
Shinya Kawaguchi, Akinori Murakami, Masato Nishida
Internal Medicine.2023; 62(5): 723. CrossRef
Gastric ectopic pancreas combined with synchronous multiple early gastric cancer: A rare case report
Zhen-Ya Zhao, Yue-Xing Lai, Ping Xu
World Journal of Clinical Cases.2023; 11(7): 1569. CrossRef
A rare case of enlarged gastric heterotopic pancreas with retention cysts: A case report and literature review
Keiso Matsubara, Michihiro Ishida, Toshiaki Morito, Tetsushi Kubota, Yasuhiro Choda, Masao Harano, Hiroyoshi Matsukawa, Hitoshi Idani, Shigehiro Shiozaki, Masazumi Okajima
International Journal of Surgery Case Reports.2020; 74: 284. CrossRef
A case of gastric heterotopic pancreas with gastroduodenal invagination
Shoko Iwahashi, Masaaki Nishi, Toshiaki Yoshimoto, Hideya Kashihara, Chie Takasu, Takuya Tokunaga, Tomohiko Miyatani, Jun Higashijima, Kozo Yoshikawa, Yuma Wada, Yoshimi Bando, Mitsuo Shimada
Surgical Case Reports.2019;[Epub] CrossRef

7,562 View
192 Download
5 Web of Science
4 Crossref

Focused Review Series: Endoscopic Accessories Used for ESD

Future Development of Endoscopic Accessories for Endoscopic Submucosal Dissection: Jae-Young Jang; Clin Endosc 2017;50(3):242-249. Published online May 31, 2017; DOI: https://doi.org/10.5946/ce.2017.073

Abstract PDF PubReader ePub

Endoscopic submucosal dissection (ESD) has recently been accepted as a standard treatment for patients with early gastric cancer (EGC), without lymph node metastases. Given the rise in the number of ESDs being performed, new endoscopic accessories are being developed and existing accessories modified to facilitate the execution of ESD and reduce complication rates. This paper examines the history underlying the development of these new endoscopic accessories and indicates future directions for the development of these accessories.

Citations

Citations to this article as recorded by

Effects of a training system that tracks the operator’s gaze pattern during endoscopic submucosal dissection on hemostasis
Takao Tonishi, Fumiaki Ishibashi, Kosuke Okusa, Kentaro Mochida, Sho Suzuki
World Journal of Gastrointestinal Endoscopy.2025;[Epub] CrossRef
A pilot study on endoscopic delivery of injectable bioadhesive for esophageal repair in a porcine model
Jie Xia, Wenxin Wang, Jinghui Guo, Jinglei Wu, Xinjian Wan
Biomedical Materials.2024; 19(5): 055023. CrossRef
Closed-loop robust control of robotic flexible endoscopy with neural network-based lumen segmentation
Yuxin Guo, Xiaoxiao Wei, Zhen Deng, Xiaochun Zheng, Bingwei He, Jianwei Zhang
Biomedical Signal Processing and Control.2023; 86: 105340. CrossRef
Automatic endoscopic navigation based on attention-based network for Nasotracheal Intubation
Zhen Deng, Xiaoxiao Wei, Xiaochun Zheng, Bingwei He
Biomedical Signal Processing and Control.2023; 86: 105035. CrossRef
Multipolar adaptive traction makes endoscopic submucosal dissection feasible for large neoplastic area of the fundus in patient with familial adenomatous polyposis
Elena De Cristofaro, Louis-Jean Masgnaux, Jean-Christophe Saurin, Jérémie Jacques, Bertrand Napoléon, Jérôme Rivory, Mathieu Pioche
Endoscopy.2023; 55(S 01): E963. CrossRef
Navigation strategy for robotic soft endoscope intervention
Wei Jiang, Yuanyuan Zhou, Chongyang Wang, Lihua Peng, Yunsheng Yang, Hao Liu
The International Journal of Medical Robotics and Computer Assisted Surgery.2020;[Epub] CrossRef
Endoscopic submucosal dissection: an update on tools and accessories
Christopher Harlow, Arun Sivananthan, Lakshmana Ayaru, Kinesh Patel, Ara Darzi, Nisha Patel
Therapeutic Advances in Gastrointestinal Endoscopy.2020; 13: 263177452095722. CrossRef

11,087 View
216 Download
7 Web of Science
7 Crossref

Reviews

How to Interpret the Pathological Report before and after Endoscopic Submucosal Dissection of Early Gastric Cancer: Dae Young Cheung, Soo-Heon Park; Clin Endosc 2016;49(4):327-331. Published online July 25, 2016; DOI: https://doi.org/10.5946/ce.2016.082

Abstract PDF PubReader ePub

Possible lymph node metastasis (LNM) and residual cancer are major concerns in endoscopic submucosal dissection (ESD) for early gastric cancer. To reduce the risk of LNM and cancer recurrence, the proper indications for ESD should be considered. Histology, size, depth of invasion, and presence of ulceration should be thoroughly evaluated before proceeding with ESD. However, with incomplete information, discrepancies often arise between the pathological diagnosis based on the forceps biopsy and that based on the totally resected specimen. In addition, the presence of lymphovascular involvement and histological homogeneity can be clarified only after ESD. If the pathological diagnosis changes after ESD, we should reevaluate the curativeness and reformulate the goal of treatment. Additional surgery is a reasonable strategy for non-curative ESD, but a patient’s other health conditions should also be considered. It is simple to read pathological reports before and after ESD, but it can be a complicated art to interpret the report and formulate an optimal approach. In this review, various considerations regarding the pathological diagnosis will be discussed.

Citations

Citations to this article as recorded by

Application of the convolution neural network in determining the depth of invasion of gastrointestinal cancer: a systematic review and meta-analysis
Ruo Wu, Kaiwen Qin, Yuxin Fang, Yuyuan Xu, Haonan Zhang, Wenhua Li, Xiaobei Luo, Zelong Han, Side Liu, Qingyuan Li
Journal of Gastrointestinal Surgery.2024; 28(4): 538. CrossRef
Comparison of two pathological processing methods for large endoscopic submucosal dissection (ESD) specimens
Zixiang Yu, Dongxian Jiang, Wen Huang, Rongkui Luo, Haixing Wang, Jieakesu Su, Jia Liu, Chen Xu, Yingyong Hou
Journal of Clinical Pathology.2023; 76(11): 757. CrossRef
Establishment and validation of a clinical diagnostic model for gastric low-grade intraepithelial neoplasia
Ting Sun, Xi-quan Ke, Meng Wang, Qi-zhi Wang
Medicine.2023; 102(46): e35515. CrossRef
Artificial Intelligence Assisted Topographic Mapping System for Endoscopic Submucosal Dissection Specimens
Yu Xiao, Zhigang Song, Shuangmei Zou, Yan You, Jie Cui, Shuhao Wang, Calvin Ku, Xi Wu, Xiaowei Xue, Wenqi Han, Weixun Zhou
Frontiers in Medicine.2022;[Epub] CrossRef
Comparative analysis of differences between preoperative endoscopic biopsy and postoperative pathological examination for diagnosis of gastric intraepithelial neoplasia
Yangqing Wu, Jianzhong Sang, Jianbo Zhou, Ying Fang
Journal of International Medical Research.2021;[Epub] CrossRef
Clinical Outcomes of Endoscopic Resection for Low-Grade Dysplasia and High-Grade Dysplasia on Gastric Pretreatment Biopsy: Korea ESD Study Group
Jung Won Jeon, Soo Jin Kim, Jae Young Jang, Sun-Moon Kim, Chul-Hyun Lim, Jae Myung Park, Su Jin Hong, Chan Gyoo Kim, Seong Woo Jeon, Si Hyung Lee, Jae Kyu Sung, Gwang Ho Baik
Gut and Liver.2021; 15(2): 225. CrossRef
Pathology perspective on endoscopic full thickness resection
Ladan Fazlollahi, Helen E. Remotti
Techniques in Gastrointestinal Endoscopy.2019; 21(1): 7. CrossRef
Optimal processing of ESD specimens to avoid pathological artifacts
L. Reggiani Bonetti, R. Manta, M. Manno, R. Conigliaro, G. Missale, G. Bassotti, V. Villanacci
Techniques in Coloproctology.2018; 22(11): 857. CrossRef

8,487 View
173 Download
8 Web of Science
8 Crossref

Borrmann Type 4 Advanced Gastric Cancer: Focus on the Development of Scirrhous Gastric Cancer: Kyoungwon Jung, Moo In Park, Sung Eun Kim, Seun Ja Park; Clin Endosc 2016;49(4):336-345. Published online July 25, 2016; DOI: https://doi.org/10.5946/ce.2016.057

Abstract PDF PubReader ePub

Early diagnosis of Borrmann type 4 advanced gastric cancer (AGC) is very important for improving the prognosis of AGC patients. Because there is no definite mass in most cases of Borrmann type 4 AGC, its accurate diagnosis via endoscopy requires an understanding of its pathogenesis and developmental process. Moreover, many people confuse linitis plastica (LP) type gastric cancer (GC), scirrhous GC, and Borrmann type 4 AGC. To distinguish each of these cancers, knowledge of their endoscopic and pathological differences is necessary, especially for LP type GCs in the developmental stage. In conclusion, diagnosis of pre-stage or latent LP type GC before progression to typical LP type GC requires the detection of IIc-like lesions in the fundic gland area. It is also crucial to identify any abnormalities such as sclerosis of the gastric wall and hypertrophy of the mucosal folds during endoscopy.

Citations

Citations to this article as recorded by

Optical histopathology based on the nonlabeling analysis with multiphoton excitation imaging
Takahiro Matsui
Pathology International.2025; 75(1): 1. CrossRef
Pulmonary Tumor Thrombotic Microangiopathy Associated With Gastric Cancer: Clinical Characteristics and Outcomes
Tae-Se Kim, Soomin Ahn, Sung-A Chang, Sung Hee Lim, Byung-Hoon Min, Yang Won Min, Hyuk Lee, Poong-Lyul Rhee, Jae J. Kim, Jun Haeng Lee
Journal of Gastric Cancer.2025; 25(2): 276. CrossRef
Application of artificial intelligence in the detection of Borrmann type 4 advanced gastric cancer in upper endoscopy (with video)
Mi Jin Oh, Jinbae Park, Jiwoon Jeon, Mina Park, Seungkyung Kang, Su Hyun Kim, Su Hee Park, Young Hoon Chang, Cheol Min Shin, Seung Joo Kang, Seunghan Lee, Sang Gyun Kim, Soo‐Jeong Cho
Cancer.2025;[Epub] CrossRef
Gastroprotective activity and physicochemical analysis of carboxymethylated gum from Anadenanthera colubrina
Letícia S. Chaves, Antonio C.P. Oliveira, Samara S. Pinho, Gabrielle C. Sousa, Ana P. Oliveira, André L.F. Lopes, Gabriella Pacheco, Isabela R.S.G. Nolêto, Lucas A.D. Nicolau, Fábio O.S. Ribeiro, Venicios G. Sombra, Thais D.S. Araújo, José R.S.A. Leite, E
International Journal of Biological Macromolecules.2024; 260: 129397. CrossRef
Circumferential gastric wall thickening as initial presentation of relapsed plasma cell leukemia
Yusuke Koba, Takahito Kawata, Akira Tamekane, Mitsumasa Watanabe
Clinical Endoscopy.2024; 57(1): 131. CrossRef
Dual-energy CT quantitative parameters to evaluate occult peritoneal metastasis in advanced gastric cancer preoperatively
Qiu-xia Feng, Zhen-ning Zhu, Qiong Li, Xi-sheng Liu
Abdominal Radiology.2024; 49(10): 3309. CrossRef
Effect of cetuximab plus FOLFOX4 regimen on clinical outcomes in advanced gastric carcinoma patients receiving evidence-based care
Hui Ying, Ren-Jun Huang, Xiao-Min Jing, Yan Li, Qun-Qiu Tong
World Journal of Clinical Cases.2024; 12(18): 3360. CrossRef
A rare cause of progressive dysphagia
Jongin Jeon, Sung Eun Kim, Sun-Ju Oh
Clinical Endoscopy.2024; 57(5): 697. CrossRef
Differential Diagnosis of Thickened Gastric Wall between Hypertrophic Gastritis and Borrmann Type 4 Advanced Gastric Cancer
Jun-young Seo, Do Hoon Kim, Ji Yong Ahn, Kee Don Choi, Hwa Jung Kim, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
Gut and Liver.2024; 18(6): 961. CrossRef
Borrmann Type Predicts Response to Preoperative Therapy in Advanced Gastric Cancer
Yuki Hirata, Annamaria Agnes, Laura R. Prakash, Paul Mansfield, Brian D. Badgwell, Naruhiko Ikoma
Journal of Gastrointestinal Cancer.2023; 54(3): 882. CrossRef
Interval Advanced Gastric Cancer After Negative Endoscopy
Tae Jun Kim, Jeung Hui Pyo, Young Hye Byun, Sung Chul Choi, Jin Pyo Hong, Yang Won Min, Hyuk Lee, Byung-Hoon Min, Poong-Lyul Rhee, Jae J. Kim, Jun Haeng Lee
Clinical Gastroenterology and Hepatology.2023; 21(5): 1205. CrossRef
Clinical Impact of Positive Surgical Margins in Gastric Adenocarcinoma in the Era of Preoperative Therapy
Yuki Hirata, Annamaria Agnes, Jeannelyn S. Estrella, Mariela Blum Murphy, Prajnan Das, Bruce D. Minsky, Jaffer A. Ajani, Brian D. Badgwell, Paul Mansfield, Naruhiko Ikoma
Annals of Surgical Oncology.2023; 30(8): 4936. CrossRef
Efficacy for diagnoses of scirrhous gastric cancer and safety of endoscopic ultrasound‐guided fine‐needle aspiration: A systematic review and meta‐analysis
Ryuhei Jinushi, Masafumi Mizuide, Yuki Tanisaka, Sakue Masuda, Kazuya Koizumi, Akiko Sasaki, Yo Ishihara, Kento Shionoya, Ryo Sato, Kei Sugimoto, Takahiro Shin, Rie Shiomi, Akashi Fujita, Shomei Ryozawa, Tsutomu Yamazaki
JGH Open.2023; 7(6): 403. CrossRef
Randomized phase II study comparing neoadjuvant 5-fluorouracil/oxaliplatin/docetaxel versus docetaxel/oxaliplatin/S-1 for patients with type 4 or large type 3 gastric cancer
Tadayoshi Hashimoto, Izuma Nakayama, Manabu Ohashi, Junki Mizusawa, Hiroshi Kawachi, Ryosuke Kita, Haruhiko Fukuda, Yukinori Kurokawa, Narikazu Boku, Takaki Yoshikawa, Masanori Terashima
Future Oncology.2023; 19(32): 2147. CrossRef
Metastatic colorectal carcinoma with signet-ring cells: Clinical, histological and molecular description from an Association des Gastro-Entérologues Oncologues (AGEO) French multicenter retrospective cohort
Marion Allart, Florence Leroy, Stephano Kim, David Sefrioui, Mihane Nayeri, Aziz Zaanan, Benoit Rousseau, Meher Ben Abdelghani, Christelle de la Fouchardière, Wulfran Cacheux, Romain Legros, Samy Louafi, David Tougeron, Olivier Bouché, Nadim Fares, Guilla
Digestive and Liver Disease.2022; 54(3): 391. CrossRef
A Transfer Learning Radiomics Nomogram for Preoperative Prediction of Borrmann Type IV Gastric Cancer From Primary Gastric Lymphoma
Bao Feng, Liebin Huang, Yu Liu, Yehang Chen, Haoyang Zhou, Tianyou Yu, Huimin Xue, Qinxian Chen, Tao Zhou, Qionglian Kuang, Zhiqi Yang, Xiangguang Chen, Xiaofeng Chen, Zhenpeng Peng, Wansheng Long
Frontiers in Oncology.2022;[Epub] CrossRef
CT-based radiomics nomograms for preoperative prediction of diffuse-type and signet ring cell gastric cancer: a multicenter development and validation cohort
Tao Chen, Jing Wu, Chunhui Cui, Qinglie He, Xunjun Li, Weiqi Liang, Xiaoyue Liu, Tianbao Liu, Xuanhui Zhou, Xifan Zhang, Xiaotian Lei, Wei Xiong, Jiang Yu, Guoxin Li
Journal of Translational Medicine.2022;[Epub] CrossRef
pCLE detects mucosal neoplastic vascular pattern in gastric linitis plastica
Mara Fornasarig, Alessandra Capuano, Stefania Maiero, Eliana Pivetta, Vincenzo Canzonieri, Claudio Belluco, Maurizio Mongiat, Renato Cannizzaro, Paola Spessotto
Clinical and Experimental Medicine.2022; 23(2): 547. CrossRef
Classification of tumor from computed tomography images: A brain-inspired multisource transfer learning under probability distribution adaptation
Yu Liu, Enming Cui
Frontiers in Human Neuroscience.2022;[Epub] CrossRef
Difficulty in distinguishing malignant gastric lymphoma from advanced gastric cancer
Kyoungwon Jung, Il Hyeong Choe, Moo In Park, Seun Ja Park, Won Moon, Sung Eun Kim, Jae Hyun Kim, Kwang Il Seo
Medicine.2021; 100(7): e24854. CrossRef
Gastric linitis plastica due to signet-ring cell carcinoma with Krukenberg tumors diagnosed by endoscopic ultrasound-guided fine-needle aspiration
Takeshi Okamoto, Hidekazu Suzuki, Katsuyuki Fukuda
Clinical Journal of Gastroenterology.2021; 14(4): 994. CrossRef
A Heterogeneity Radiomic Nomogram for Preoperative Differentiation of Primary Gastric Lymphoma From Borrmann Type IV Gastric Cancer
Bao Feng, Liebin Huang, Changlin Li, Yong Quan, Yehang Chen, Huimin Xue, Qinxian Chen, Shanlin Sun, Ronggang Li, Wansheng Long
Journal of Computer Assisted Tomography.2021; 45(2): 191. CrossRef
Comparative Outcomes of Laparoscopic Gastrectomy and Open Gastrectomy for Scirrhous Gastric Cancer: A Multicenter Retrospective Cohort Study
Yusuke Fujita, Tatsuto Nishigori, Yoshio Kadokawa, Atsushi Itami, Masato Kondo, Hisahiro Hosogi, Seiichiro Kanaya, Hironori Kawada, Hiroaki Hata, Michihiro Yamamoto, Yousuke Kinjo, Eiji Tanaka, Dai Manaka, Seiji Satoh, Hiroshi Okabe, Shigeru Tsunoda, Masa
Annals of Surgery Open.2021; 2(2): e063. CrossRef
Prognosis of poorly cohesive gastric cancer after complete cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (CYTO-CHIP study)
P E Bonnot, A Lintis, F Mercier, N Benzerdjeb, G Passot, M Pocard, B Meunier, J M Bereder, K Abboud, F Marchal, F Quenet, D Goere, S Msika, C Arvieux, N Pirro, R Wernert, P Rat, J Gagnière, J H Lefevre, T Courvoisier, R Kianmanesh, D Vaudoyer, M Rivoire,
British Journal of Surgery.2021; 108(10): 1225. CrossRef
Limited Clinical Significance of Splenectomy and Splenic Hilar Lymph Node Dissection for Type 4 Gastric Cancer
Aina Kunitomo, Kazunari Misawa, Yuichi Ito, Seiji Ito, Eiji Higaki, Seiji Natsume, Takashi Kinoshita, Tetsuya Abe, Koji Komori, Yasuhiro Shimizu
Journal of Gastric Cancer.2021; 21(4): 392. CrossRef
Suppurative gastritis as a rare cause of acute abdomen and septic shock in a pregnant woman: a case report
Guido Marzocchi, Davide Giusti, Maurizio Cervellera, Francesco Monteduro
European Journal of Medical Case Reports.2021;[Epub] CrossRef
Development and internal validation of a diagnostic score for gastric linitis plastica
J. Vivier-Chicoteau, J. Lambert, R. Coriat, P. E. Bonnot, D. Goere, B. Roche, M. Dior, G. Goujon, S. Morgant, M. Pocard, O. Glehen, T. Aparicio, Jean-Marc Gornet
Gastric Cancer.2020; 23(4): 639. CrossRef
Serine threonine kinase 11/liver kinase B1 mutation in sporadic scirrhous-type gastric cancer cells
Sadaaki Nishimura, Masakazu Yashiro, Tomohiro Sera, Yurie Yamamoto, Yukako Kushitani, Atsushi Sugimoto, Shuhei Kushiyama, Shingo Togano, Kenji Kuroda, Tomohisa Okuno, Yoshiki Murakami, Masaichi Ohira
Carcinogenesis.2020; 41(11): 1616. CrossRef
Establishment of a New Scirrhous Gastric Cancer Cell Line with FGFR2 Overexpression, OCUM-14
Tomohisa Okuno, Masakazu Yashiro, Go Masuda, Shingo Togano, Kenji Kuroda, Yuichiro Miki, Kosei Hirakawa, Masahiko Ohsawa, Hideki Wanibuchi, Masaichi Ohira
Annals of Surgical Oncology.2019; 26(4): 1093. CrossRef
IgM‐ Kappa type multiple myeloma with simultaneous gastro‐esophageal involvement simulating linitis plastica
Sheng‐Wen Huang, Hugo You‐Hsien Lin, Sheau‐Fang Yang, Yu‐Chung Su
The Kaohsiung Journal of Medical Sciences.2018; 34(6): 357. CrossRef
Phlegmonous Gastritis: A Report of Three Cases with Clinical and Imaging Features
Mitsuaki Ishioka, Noboru Watanabe, Masayuki Sawaguchi, Sho Fukuda, Hisashi Shiga, Tamotsu Matsuhashi, Mario Jin, Katsunori Iijima
Internal Medicine.2018; 57(15): 2185. CrossRef
Comparing single oral contrast-enhanced ultrasonography and double contrast-enhanced ultrasonography in the preoperative Borrmann classification of advanced gastric cancer
Liang Wang, XiaoHua Wang, HongJu Kou, HuiLiao He, Mingdong Lu, LingLing Zhou, Yan Yang
Oncotarget.2018; 9(9): 8716. CrossRef
Endoscopic ultrasound‑guided fine‑needle aspiration biopsy for diagnosis of gastric linitis plastica with negative malignant endoscopy biopsies
Yingjian Ye, Shiyun Tan
Oncology Letters.2018;[Epub] CrossRef
CT-based radiomics signature for differentiating Borrmann type IV gastric cancer from primary gastric lymphoma
Zelan Ma, Mengjie Fang, Yanqi Huang, Lan He, Xin Chen, Cuishan Liang, Xiaomei Huang, Zixuan Cheng, Di Dong, Changhong Liang, Jiajun Xie, Jie Tian, Zaiyi Liu
European Journal of Radiology.2017; 91: 142. CrossRef
The significance of a nineteenth century definition in the era of genomics: linitis plastica
Annamaria Agnes, Jeannelyn S. Estrella, Brian Badgwell
World Journal of Surgical Oncology.2017;[Epub] CrossRef
Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions
Takahiro Matsui, Hiroki Mizuno, Takao Sudo, Junichi Kikuta, Naotsugu Haraguchi, Jun-ichiro Ikeda, Tsunekazu Mizushima, Hirofumi Yamamoto, Eiichi Morii, Masaki Mori, Masaru Ishii
Scientific Reports.2017;[Epub] CrossRef
A case report of gastric linitis plastica diagnosed by endoscopic ultrasound-guided fine needle aspiration
Shinji Muraoka, Kouhei Tsuchida, Mari Iwasaki, Naoya Izawa, Hidehito Jinnai, Toshinori Komatsubara, Misako Tsunemi, Fumi Sakuma, Ken Kashima, Ko Fukushi, Hideyuki Hiraishi
Medicine.2017; 96(50): e8937. CrossRef

20,585 View
371 Download
40 Web of Science
37 Crossref

Treatment Strategy after Incomplete Endoscopic Resection of Early Gastric Cancer: Sang Gyun Kim; Clin Endosc 2016;49(4):332-335. Published online July 20, 2016; DOI: https://doi.org/10.5946/ce.2016.069

Abstract PDF PubReader ePub

Endoscopic resection of early gastric cancer is defined as incomplete when tumor cells are found at the resection margin upon histopathological examination. However, a tumor-positive resection margin does not always indicate residual tumor; it can also be caused by tissue contraction during fixation, by the cautery effect during endoscopic resection, or by incorrect histopathological mapping. Cases of highly suspicious residual tumor require additional endoscopic or surgical resection. For inoperable patients, argon plasma coagulation can be used as an alternative endoscopic treatment. Immediately after the incomplete resection or residual tumor has been confirmed by the pathologist, clinicians should also decide upon any additional treatment to be carried out during the follow-up period.

Citations

Citations to this article as recorded by

Long-term Outcomes of Patients With Early Gastric Cancer Who Had Lateral Resection Margin-Positive Tumors Based on Pathology Following Endoscopic Submucosal Dissection
Jun Hee Lee, Sang Gyun Kim, Soo-Jeong Cho
Journal of Gastric Cancer.2024; 24(2): 199. CrossRef
Clinico-pathologic determinants of non-e-curative outcome following en-bloc endoscopic submucosal dissection in patients with early gastric neoplasia
Kidane Siele Embaye, Chao Zhang, Matiwos Araya Ghebrehiwet, Zhihao Wang, Fengdi Zhang, Liwei Liu, Shenghui Qin, Lingzhi Qin, Jun Wang, Xi Wang
BMC Cancer.2021;[Epub] CrossRef
Risk Factors and Clinical Outcomes of Non-Curative Resection in Patients with Early Gastric Cancer Treated with Endoscopic Submucosal Dissection: A Retrospective Multicenter Study in Korea
Si Hyung Lee, Min Cheol Kim, Seong Woo Jeon, Kang Nyeong Lee, Jong Jae Park, Su Jin Hong
Clinical Endoscopy.2020; 53(2): 196. CrossRef
Long-term outcomes after noncurative endoscopic resection of early gastric cancer: the optimal time for additional endoscopic treatment
Mi Young Jeon, Jun Chul Park, Kyu Yeon Hahn, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
Gastrointestinal Endoscopy.2018; 87(4): 1003. CrossRef
Prediction model for non-curative resection of endoscopic submucosal dissection in patients with early gastric cancer
Eun Hye Kim, Jun Chul Park, In Ji Song, Yeong Jin Kim, Dong Hoo Joh, Kyu Yeon Hahn, Yong Kang Lee, Ha Yan Kim, Hyunsoo Chung, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
Gastrointestinal Endoscopy.2017; 85(5): 976. CrossRef

8,858 View
142 Download
6 Web of Science
5 Crossref

Focused Review Series: Image Enhanced Endoscopy

Clinical Application of Magnifying Endoscopy with Narrow-Band Imaging in the Stomach: Kenshi Yao; Clin Endosc 2015;48(6):481-490. Published online November 30, 2015; DOI: https://doi.org/10.5946/ce.2015.48.6.481

Abstract PDF PubReader ePub

Magnifying endoscopy with narrow-band imaging (M-NBI) can visualize superficial microanatomies in the stomach. The normal morphology of the microanatomy visualized by M-NBI differs according to the part of the stomach. The gastric fundic glandular mucosa appears as a regular honeycomb-like subepithelial capillary network (SECN) pattern with a regular collecting venule pattern and regular oval crypt opening with circular marginal crypt epithelium (MCE) pattern. The gastric pyloric glandular mucosa displays a regular coil-shaped SECN pattern and regular polygonal or curved MCE pattern. For a diagnosis of early gastric cancer using M-NBI, the vessel plus surface classification system was developed. This system is clinically useful for the differential diagnosis of focal gastritis and small depressed cancer and for determining the horizontal extent of early gastric cancer for successful endoscopic resection. Advantages of M-NBI over conventional endoscopic imaging techniques with white light include accurate diagnosis and cost effectiveness. This technique is a breakthrough in the endoscopic diagnostic field.

Citations

Citations to this article as recorded by

Correlation between White Globe Appearance and Clinicopathologic Characteristics in Early Gastric Cancer
Dae Jin Jung, Gwang Ha Kim, Kyungbin Kim, Hye Kyung Jeon, Dong Chan Joo, Moon Won Lee, Bong Eun Lee
Gut and Liver.2025; 19(1): 50. CrossRef
Factors influencing lateral margin diagnosis challenges in Barrett’s esophageal cancer: a bicenter retrospective study in Japan
Ippei Tanaka, Shuhei Unno, Kazuki Yamamoto, Yoshitaka Nawata, Kimihiro Igarashi, Tomoki Matsuda, Dai Hirasawa
Clinical Endoscopy.2025; 58(1): 85. CrossRef
Could near focus endoscopy, narrow-band imaging, and acetic acid improve the visualization of microscopic features of stomach mucosa?
Admir Kurtcehajic, Enver Zerem, Tomislav Bokun, Ervin Alibegovic, Suad Kunosic, Ahmed Hujdurovic, Amir Tursunovic, Kenana Ljuca
World Journal of Gastrointestinal Endoscopy.2024; 16(3): 157. CrossRef
The investigation of volatile organic compounds in diagnosing (early) esophageal squamous cell carcinoma and gastric adenocarcinoma
Hang Yang, Chengfang Xiang, Yi Mou, Xinyue Zhou, Wenwen Li, Yixiang Duan, Bing Hu
Journal of Cancer Research and Clinical Oncology.2023; 149(10): 7029. CrossRef
Approach for the Management of Indefinite-for-neoplasia Lesions Detected on Gastric Mucosal Biopsy
Dae Gon Ryu, Cheol Woong Choi
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2023; 23(1): 7. CrossRef
Magnifying Endoscopy with Narrow-Band Imaging for Duodenal Neuroendocrine Tumors
Gwang Ha Kim, Kiyoun Yi, Dong Chan Joo, Moon Won Lee, Hye Kyung Jeon, Bong Eun Lee
Journal of Clinical Medicine.2023; 12(9): 3106. CrossRef
Lightweight deep learning model incorporating an attention mechanism and feature fusion for automatic classification of gastric lesions in gastroscopic images
Lingxiao Wang, Yingyun Yang, Aiming Yang, Ting Li
Biomedical Optics Express.2023; 14(9): 4677. CrossRef
Advanced gastric cancer detected during regular follow-up after eradication of Helicobacter pylori
Masami Tanaka, Daisuke Kikuchi, Hiroyuki Odagiri, Atsuko Hosoi, Yugo Suzuki, Takayuki Okamura, Yorinari Ochiai, Junnosuke Hayasaka, Yutaka Mitsunaga, Kosuke Nomura, Satoshi Yamashita, Akira Matsui, Yutaka Takazawa, Shu Hoteya
Clinical Journal of Gastroenterology.2022; 15(2): 358. CrossRef
Usefulness of artificial intelligence in early gastric cancer
Alba Panarese
WArtificial Intelligence in Cancer.2022; 3(2): 17. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Gastric Cancer
Dalton A. Norwood, Eleazar Montalvan-Sanchez, Ricardo L. Dominguez, Douglas R. Morgan
Gastroenterology Clinics of North America.2022; 51(3): 501. CrossRef
Demarcation Line Determination for Diagnosis of Gastric Cancer Disease Range Using Unsupervised Machine Learning in Magnifying Narrow-Band Imaging
Shunsuke Okumura, Misa Goudo, Satoru Hiwa, Takeshi Yasuda, Hiroaki Kitae, Yuriko Yasuda, Akira Tomie, Tatsushi Omatsu, Hiroshi Ichikawa, Nobuaki Yagi, Tomoyuki Hiroyasu
Diagnostics.2022; 12(10): 2491. CrossRef
Clinical Role of Magnifying Endoscopy with Narrow-band Imaging in the Diagnosis of Early Gastric Cancer
Soo In Choi
Journal of Digestive Cancer Research.2022; 10(2): 56. CrossRef
NBI utility in oncologic surgery: An organ by organ review
Francesca Boscolo Nata, Giancarlo Tirelli, Vincenzo Capriotti, Alberto Vito Marcuzzo, Erica Sacchet, Azzurra Nicole Šuran-Brunelli, Nicolò de Manzini
Surgical Oncology.2021; 36: 65. CrossRef
Magnifying Power: New Endoscopic Tools for the Diagnosis of Krukenberg Tumor
Hannah Ramrakhiani, Aarushi K. Thaker, Albert Pisani, Ankur Sangoi, George Triadafilopoulos
Digestive Diseases and Sciences.2021; 66(10): 3296. CrossRef
Identifying early gastric cancer under magnifying narrow-band images with deep learning: a multicenter study
Hao Hu, Lixin Gong, Di Dong, Liang Zhu, Min Wang, Jie He, Lei Shu, Yiling Cai, Shilun Cai, Wei Su, Yunshi Zhong, Cong Li, Yongbei Zhu, Mengjie Fang, Lianzhen Zhong, Xin Yang, Pinghong Zhou, Jie Tian
Gastrointestinal Endoscopy.2021; 93(6): 1333. CrossRef
Dynamic diagnosis of early gastric cancer with microvascular blood flow rate using magnifying endoscopy (with video): A pilot study
Hiroya Ueyama, Noboru Yatagai, Atsushi Ikeda, Yoichi Akazawa, Hiroyuki Komori, Tsutomu Takeda, Kohei Matsumoto, Kumiko Ueda, Kenshi Matsumoto, Daisuke Asaoka, Mariko Hojo, Takashi Yao, Akihito Nagahara
Journal of Gastroenterology and Hepatology.2021; 36(7): 1927. CrossRef
Diagnostic Ability of Magnifying Narrow-Band Imaging for the Extent of Early Gastric Cancer: A Systematic Review and Meta-Analysis
Yingying Hu, Xueqin Chen, Maher Hendi, Jianmin Si, Shujie Chen, Yanyong Deng, Bruno Annibale
Gastroenterology Research and Practice.2021; 2021: 1. CrossRef
Image-Enhanced Endoscopy and Its Corresponding Histopathology in the Stomach
Hisashi Doyama, Hiroyoshi Nakanishi, Kenshi Yao
Gut and Liver.2021; 15(3): 329. CrossRef
Systematic Review on Optical Diagnosis of Early Gastrointestinal Neoplasia
Andrej Wagner, Stephan Zandanell, Tobias Kiesslich, Daniel Neureiter, Eckhard Klieser, Josef Holzinger, Frieder Berr
Journal of Clinical Medicine.2021; 10(13): 2794. CrossRef
Sporadic fundic gland polyps with dysplasia or carcinoma: Clinical and endoscopic characteristics
Wataru Sano, Fumihiro Inoue, Daizen Hirata, Mineo Iwatate, Santa Hattori, Mikio Fujita, Yasushi Sano
World Journal of Gastrointestinal Oncology.2021; 13(7): 487. CrossRef
Sporadic fundic gland polyps with dysplasia or carcinoma: Clinical and endoscopic characteristics
Wataru Sano, Fumihiro Inoue, Daizen Hirata, Mineo Iwatate, Santa Hattori, Mikio Fujita, Yasushi Sano
World Journal of Gastrointestinal Oncology.2021; 13(7): 662. CrossRef
Controversies in EUS: Do we need miniprobes?
Hans Seifert, Pietro Fusaroli, PaoloGiorgio Arcidiacono, Barbara Braden, Felix Herth, Michael Hocke, Alberto Larghi, Bertrand Napoleon, Mihai Rimbas, BogdanSilvio Ungureanu, Adrian Sãftoiu, AnandV Sahai, ChristophF Dietrich
Endoscopic Ultrasound.2021; 10(4): 246. CrossRef
Application of Current Image-Enhanced Endoscopy in Gastric Diseases
Wansik Lee
Clinical Endoscopy.2021; 54(4): 477. CrossRef
Feasibility of standardized procedures of white light gastroscopy for clinical practice: A multicenter study in China
Qiang Wang, Sheng Yu Zhang, Xi Wu, Fang Yao, Wei Xun Zhou, Ning Li Chai, Shu Tian Zhang, Jian Yu Hao, Jing Wu, Ji Chang Zhang, Bao Hong Xu, Li Xia Hu, Ai Ming Yang
Journal of Digestive Diseases.2021; 22(11): 656. CrossRef
Convolutional neural network for the diagnosis of early gastric cancer based on magnifying narrow band imaging
Lan Li, Yishu Chen, Zhe Shen, Xuequn Zhang, Jianzhong Sang, Yong Ding, Xiaoyun Yang, Jun Li, Ming Chen, Chaohui Jin, Chunlei Chen, Chaohui Yu
Gastric Cancer.2020; 23(1): 126. CrossRef
Endoscopic acanthosis nigricans appearance: A novel specific marker for diagnosis of low‐grade intraepithelial neoplasia
Jinnian Cheng, Xianjun Xu, Qian Zhuang, Shengzheng Luo, Xiaoyuan Gong, Xiaowan Wu, Xinjian Wan, Hui Zhou
Journal of Gastroenterology and Hepatology.2020; 35(8): 1372. CrossRef
Clinicopathological features of early gastric cancers arising in Helicobacter pylori uninfected patients
Chiko Sato, Kingo Hirasawa, Yoko Tateishi, Yuichiro Ozeki, Atsushi Sawada, Ryosuke Ikeda, Takehide Fukuchi, Masafumi Nishio, Ryosuke Kobayashi, Makomo Makazu, Hiroaki Kaneko, Yoshiaki Inayama, Shin Maeda
World Journal of Gastroenterology.2020; 26(20): 2618. CrossRef
Narrowband imaging with near‐focus magnification for discriminating the gastric tumor margin before endoscopic resection: A prospective randomized multicenter trial
Jung‐Wook Kim, Yunho Jung, Jae‐Young Jang, Gwang Ha Kim, Byoung Wook Bang, Jun Chul Park, Hyuk Soon Choi, Jun‐Hyung Cho
Journal of Gastroenterology and Hepatology.2020; 35(11): 1930. CrossRef
Clinical applicability of gastroscopy with narrow-band imaging for the diagnosis of Helicobacter pylori gastritis, precancerous gastric lesion, and neoplasia
Jun-Hyung Cho, Seong Ran Jeon, So-Young Jin
World Journal of Clinical Cases.2020; 8(14): 2902. CrossRef
A new exploration of white globe appearance (WGA) in ulcerative lesions
Jinnian Cheng, Jie Xia, Qian Zhuang, Xianjun Xu, Xiaowan Wu, Xinjian Wan, Jing Wang, Hui Zhou
Zeitschrift für Gastroenterologie.2020; 58(08): 754. CrossRef
Tapering body stiffness shortens upper gastrointestinal examination via transoral insertion with ultrathin endoscope
Satoshi Ono, Shun Ito, Kyohei Maejima, Shosuke Hosaka, Kiyotaka Umeki, Shin-ichiro Sato
Endoscopy International Open.2020; 08(12): E1748. CrossRef
Diagnosis and treatment of the gastric adenoma and Helicobacter pylori-negative atrophic gastritis: clinical case
R.O. Kuvaev, O.B. Tkachenko, A.N. Sidorova, E.A. Krainova, S.V. Kashin, A.A. Kuvaeva
Dokazatel'naya gastroenterologiya.2020; 9(4): 83. CrossRef
Endoscopic microanatomy of the normal gastrointestinal mucosa with narrow band technology and magnification
Hugo Uchima, Kenshi Yao
Gastroenterología y Hepatología.2019; 42(2): 117. CrossRef
Endoscopic microanatomy of the normal gastrointestinal mucosa with narrow band technology and magnification
Hugo Uchima, Kenshi Yao
Gastroenterología y Hepatología (English Edition).2019; 42(2): 117. CrossRef
How to adjust endoscopic findings to histopathological findings of the stomach: a “histopathology-oriented” correspondence method helps to understand endoscopic findings
Yasuko Fujita, Mitsuo Kishimoto, Osamu Dohi, Kazuhiro Kamada, Atsushi Majima, Reiko Kimura-Tsuchiya, Nobuaki Yagi, Hideyuki Konishi, Yuji Naito, Yoshinori Harada, Hideo Tanaka, Eiichi Konishi, Tamotsu Sugai, Akio Yanagisawa
Gastric Cancer.2018; 21(3): 573. CrossRef
Diagnostic performance of routine esophagogastroduodenoscopy using magnifying endoscope with narrow‐band imaging for gastric cancer
Shoichi Yoshimizu, Yorimasa Yamamoto, Yusuke Horiuchi, Masami Omae, Toshiyuki Yoshio, Akiyoshi Ishiyama, Toshiaki Hirasawa, Tomohiro Tsuchida, Junko Fujisaki
Digestive Endoscopy.2018; 30(1): 71. CrossRef
Efficacy of narrow-band imaging for detecting intestinal metaplasia in adult patients with symptoms of dyspepsia
S. Sobrino-Cossío, J.M. Abdo Francis, F. Emura, E.S. Galvis-García, M.L. Márquez Rocha, G. Mateos-Pérez, C.B. González-Sánchez, N. Uedo
Revista de Gastroenterología de México (English Edition).2018; 83(3): 245. CrossRef
La eficacia de la imagen de banda estrecha para la detección de metaplasia intestinal en pacientes adultos con síntomas de dispepsia
S. Sobrino-Cossío, J.M. Abdo Francis, F. Emura, E.S. Galvis-García, M.L. Márquez Rocha, G. Mateos-Pérez, C.B. González-Sánchez, N. Uedo
Revista de Gastroenterología de México.2018; 83(3): 245. CrossRef
Role of SpyGlass-DStm in the preoperative assessment of pancreatic intraductal papillary mucinous neoplasm involving the main pancreatic duct
Takao Ohtsuka, Yoshitaka Gotoh, Yohei Nakashima, Yoshifumi Okayama, So Nakamura, Makiko Morita, Mohammed Y.F. Aly, Vittoria Vanessa D.M. Velasquez, Yasuhisa Mori, Yoshihiko Sadakari, Kohei Nakata, Yoshihiro Miyasaka, Kousei Ishigami, Nao Fujimori, Naoki M
Pancreatology.2018; 18(5): 566. CrossRef
A Theoretical Model: Elastic Analysis of the Evolution of the Crypt Opening Between the Fundic Gland and the Pyloric Gland
Fei Xiong, Xiao Gang Liu
Frontiers in Physiology.2018;[Epub] CrossRef
Advanced imaging and therapeutic endoscopy
Chaitanya Pant, Mojtaba S. Olyaee, Amit Rastogi
Techniques in Gastrointestinal Endoscopy.2017; 19(3): 151. CrossRef
An update on gastric cancer
Syed A. Ahmad, Brent T. Xia, Christina E. Bailey, Daniel E. Abbott, Beth A. Helmink, Meghan C. Daly, Ramya Thota, Cameron Schlegal, Leah K. Winer, S. Ameen Ahmad, Ali H. Al Humaidi, Alexander A Parikh
Current Problems in Surgery.2016; 53(10): 449. CrossRef

20,741 View
894 Download
41 Web of Science
43 Crossref

Review

Improving the Endoscopic Detection Rate in Patients with Early Gastric Cancer: Hee Seok Moon; Clin Endosc 2015;48(4):291-296. Published online July 24, 2015; DOI: https://doi.org/10.5946/ce.2015.48.4.291

Abstract PDF PubReader ePub

Endoscopists should ideally possess both sufficient knowledge of the endoscopic gastrointestinal disease findings and an appropriate attitude. Before performing endoscopy, the endoscopist must identify several risk factors of gastric cancer, including the patient's age, comorbidities, and drug history, a family history of gastric cancer, previous endoscopic findings of atrophic gastritis or intestinal metaplasia, and a history of previous endoscopic treatments. During endoscopic examination, the macroscopic appearance is very important for the diagnosis of early gastric cancer; therefore, the endoscopist should have a consistent and organized endoscope processing technique and the ability to comprehensively investigate the entire stomach, even blind spots.

Citations

Citations to this article as recorded by

Artificial Intelligence-Powered Quality Assurance: Transforming Diagnostics, Surgery, and Patient Care—Innovations, Limitations, and Future Directions
Yoojin Shin, Mingyu Lee, Yoonji Lee, Kyuri Kim, Taejung Kim
Life.2025; 15(4): 654. CrossRef
Estrategias para optimizar la detección endoscópica de cáncer gástrico temprano
Nicolás Zuluaga Arbeláez, Raúl Pinilla Morales, Mario Rey Ferro, Martin Alonso Gómez Zuleta
Revista colombiana de Gastroenterología.2025; 40(1): 57. CrossRef
Artificial Intelligence-Based Classification of Anatomical Sites in Esophagogastroduodenoscopy Images
Peng Yuan, Zhong-Hua Ma, Yan Yan, Shi-Jie Li, Jing Wang, Qi Wu
International Journal of General Medicine.2024; Volume 17: 6127. CrossRef
Preoperative diagnosis of tumor depth in gastric cancer using transabdominal ultrasonography compared to using endoscopy and computed tomography
Shinya Urakawa, Toshiya Michiura, Shinji Tokuyama, Yasunari Fukuda, Yasuaki Miyazaki, Nobuyasu Hayashi, Kazuo Yamabe
Surgical Endoscopy.2023; 37(5): 3807. CrossRef
Clinical and endoscopic features of metachronous gastric cancer with possible lymph node metastasis after endoscopic submucosal dissection and Helicobacter pylori eradication
Haruhisa Suzuki, Satoru Nonaka, Iruru Maetani, Takahisa Matsuda, Seiichiro Abe, Shigetaka Yoshinaga, Ichiro Oda, Yukinori Yamagata, Takaki Yoshikawa, Yutaka Saito
Gastric Cancer.2023; 26(5): 743. CrossRef
Identification of gaze pattern and blind spots by upper gastrointestinal endoscopy using an eye-tracking technique
Ayoung Lee, Hyunsoo Chung, Yejin Cho, Jue Lie Kim, Jinju Choi, Eunwoo Lee, Bokyung Kim, Soo-Jeong Cho, Sang Gyun Kim
Surgical Endoscopy.2022; 36(4): 2574. CrossRef
Endoscopic diagnosis of early gastric cancer
Dong Chan Joo, Gwang Ha Kim
Journal of the Korean Medical Association.2022; 65(5): 267. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef
Redundant Electromagnetic Control of an Endoscopic Magnetic Capsule Driven by Multiple Electromagnets Configuration
Jayoung Kim, Han-Sol Lee, Manh Cuong Hoang, Seonghwan Jeong, Jae-Seung Kim, Cheong Lee, Byungjeon Kang, Jonghee Lee, Young-Don Son, Seungmin Bang, Eunpyo Choi, Jong-Oh Park, Chang-Sei Kim
IEEE Transactions on Industrial Electronics.2022; 69(11): 11370. CrossRef
Intelligent detection endoscopic assistant: An artificial intelligence-based system for monitoring blind spots during esophagogastroduodenoscopy in real-time
Yan-Dong Li, Shu-Wen Zhu, Jiang-Ping Yu, Rong-Wei Ruan, Zhao Cui, Yi-Ting Li, Mei-Chao Lv, Huo-Gen Wang, Ming Chen, Chao-Hui Jin, Shi Wang
Digestive and Liver Disease.2021; 53(2): 216. CrossRef
A comparative time‐dependent study of hematology, serum gastrin concentrations, and gastroscopic assessment of meloxicam‐induced gastric ulceration in dogs
Ahmed Elfadadny, Ahmed S. Mandour, Rokaia F. Ragab, Khalaf F. Alsharif, Gaber El‐Saber Batiha, Haney Samir, Noha A. Beder
Journal of Veterinary Internal Medicine.2021; 35(5): 2196. CrossRef
Comparing blind spots of unsedated ultrafine, sedated, and unsedated conventional gastroscopy with and without artificial intelligence: a prospective, single-blind, 3-parallel-group, randomized, single-center trial
Di Chen, Lianlian Wu, Yanxia Li, Jun Zhang, Jun Liu, Li Huang, Xiaoda Jiang, Xu Huang, Ganggang Mu, Shan Hu, Xiao Hu, Dexin Gong, Xinqi He, Honggang Yu
Gastrointestinal Endoscopy.2020; 91(2): 332. CrossRef
Đánh giá kết quả chẩn đoán và điều trị ung thư dạ dày sớm tại Bệnh viện Trung ương Huế
Nhật Tân Phan
Journal of Clinical Medicine- Hue Central Hospital.2020;[Epub] CrossRef
Taking More Gastroscopy Images Increases the Detection Rate of Clinically Significant Gastric Lesions: Validation of a Systematic Screening Protocol for the Stomach
Ja In Lee, Joon Sung Kim, Byung-Wook Kim, Cheal Wung Huh
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2020; 20(3): 225. CrossRef
TriZ-a rotation-tolerant image feature and its application in endoscope-based disease diagnosis
Ruixue Zhao, Ruochi Zhang, Tongyu Tang, Xin Feng, Jialiang Li, Yue Liu, Renxiang Zhu, Guangze Wang, Kangning Li, Wenyang Zhou, Yunfei Yang, Yuzhao Wang, Yuanjie Ba, Jiaojiao Zhang, Yang Liu, Fengfeng Zhou
Computers in Biology and Medicine.2018; 99: 182. CrossRef
Linked colour imaging benefits the endoscopic diagnosis of distal gastric diseases
Xiaotian Sun, Yiliang Bi, Tenghui Dong, Min Min, Wei Shen, Yang Xu, Yan Liu
Scientific Reports.2017;[Epub] CrossRef
High-Risk Gastric Pathology and Prevalent Autoimmune Diseases in Patients with Pernicious Anemia
Jing W. Hughes, Brian D. Muegge, Garry S. Tobin, Marina Litvin, Lulu Sun, Jose B. Saenz, C. Prakash Gyawali, Janet B. McGill
Endocrine Practice.2017; 23(11): 1297. CrossRef
Long-term clinical outcomes of laparoscopy-assisted distal gastrectomy versus open distal gastrectomy for early gastric cancer
Wei Lu, Jian Gao, Jingyun Yang, Yijian Zhang, Wenjie Lv, Jiasheng Mu, Ping Dong, Yingbin Liu
Medicine.2016; 95(27): e3986. CrossRef
Highlights from the 52nd Seminar of the Korean Society of Gastrointestinal Endoscopy
Eun Young Kim, Il Ju Choi, Kwang An Kwon, Ji Kon Ryu, Ki Baik Hahm
Clinical Endoscopy.2015; 48(4): 269. CrossRef
Detection of gastric cancer using transabdominal ultrasonography is associated with tumor diameter and depth of invasion
MINORU TOMIZAWA, FUMINOBU SHINOZAKI, KAZUNORI FUGO, RUMIKO HASEGAWA, YOSHINORI SHIRAI, YASUFUMI MOTOYOSHI, TAKAO SUGIYAMA, SHIGENORI YAMAMOTO, TAKASHI KISHIMOTO, NAOKI ISHIGE
Experimental and Therapeutic Medicine.2015; 10(5): 1835. CrossRef

19,337 View
407 Download
18 Web of Science
20 Crossref

Case Report

Liver Metastasis of Early Gastric Cancer with Mixed Histology after Endoscopic Submucosal Dissection: Yang Hee Han, Jong Kyu Park, Jun Sung Kwon, Young Don Kim, Woo Jin Jeong, Sang Jin Lee, Koon Hee Han, Gab Jin Cheon; Clin Endosc 2015;48(3):247-250. Published online May 29, 2015; DOI: https://doi.org/10.5946/ce.2015.48.3.247

Abstract PDF PubReader ePub

The Japanese Classification of Gastric Carcinoma histologically classifies endoscopically resected gastric cancer into differentiated and undifferentiated types according to the presence or absence of tubular structures on histology. The former includes papillary adenocarcinoma and tubular types, and the latter includes poorly differentiated adenocarcinoma, signet ring cell carcinoma and mucinous adenocarcinoma. However, gastric cancer sometimes contains a mixture of differentiated and undifferentiated components, and the clinical outcomes of the histological mixture are unknown, especially following endoscopic resection of early gastric cancer (EGC). This case was within the guideline indications for endoscopic submucosal resection (ESD), although it contained a partly signet ring cell carcinoma component; it recurred after 19 months with multiple lymph node and liver metastases. This case shows that additional surgical resection after ESD should be performed for patients with any mixed signet ring cell component, even in mild or moderately differentiated EGC.

Citations

Citations to this article as recorded by

Clinical significance of computed tomography-detected ascites in gastric cancer patients with peritoneal metastases
Su Hwan Kim, Young Ho Choi, Ji Won Kim, Sohee Oh, Seohui Lee, Byeong Gwan Kim, Kook Lae Lee
Medicine.2018; 97(8): e9343. CrossRef
A primary tumor of mixed histological type is a novel poor prognostic factor for patients undergoing resection of liver metastasis from gastric cancer
Naoki Ikari, Kiyoaki Taniguchi, Akiko Serizawa, Takuji Yamada, Masakazu Yamamoto, Toru Furukawa
Journal of Hepato-Biliary-Pancreatic Sciences.2017; 24(5): 281. CrossRef

8,299 View
100 Download
3 Web of Science
2 Crossref

First
Prev
Page of 4
Next
Last

TOP