Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is routinely performed for establishing tissue diagnosis in patients with gastrointestinal tumors. The concept of delivering chemotherapy based on molecular markers and the ability to establish a reliable diagnosis in lieu of an onsite cytopathologist has fuelled the recent trend in procuring core tissue by means of EUS-guided fine needle biopsy. To overcome the technical limitations induced by the rigidity of the Trucut biopsy needle, a new ProCore needle with reverse bevel technology has been developed. Recent data suggests that the newly developed flexible 19 gauge needle can also procure core tissue and has easy maneuverability when navigating the transduodenal route. Irrespective of the needles being used, the best clinical outcomes can be attained only by practicing evidence-based techniques, procuring adequate quantity of sample for ancillary studies, and processing the specimens appropriately.

Citations

Citations to this article as recorded by  

• A Meta-Analysis Comparing Endoscopic Ultrasound-guided Fine-needle Aspiration With Endoscopic Ultrasound-guided Fine-needle Biopsy
  Zhiwang Li, Wei Liu, Xiaoda Xu, Peiyu Li
  Journal of Clinical Gastroenterology.2022; 56(8): 668.     CrossRef
• Examination of endobronchial ultrasound-guided transbronchial needle aspiration using a puncture needle with a side trap
  Kazuhito Miyazaki, Yuya Hirasawa, Masaharu Aga, Naoto Aiko, Yusuke Hamakawa, Yuri Taniguchi, Yuki Misumi, Yoko Agemi, Tsuneo Shimokawa, Hiroyuki Hayashi, Katsuhiko Naoki, Hiroaki Okamoto
  Scientific Reports.2021;[Epub]     CrossRef
• Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study
  Germana de Nucci, Maria Chiara Petrone, Nicola Imperatore, Edoardo Forti, Roberto Grassia, Silvia Giovanelli, Laura Ottaviani, Vincenzo Mirante, Giuseppe Sabatino, Carlo Fabbri, Mauro Manno, Paolo Giorgio Arcidiacono, Gianpiero Manes
  Clinical Endoscopy.2021; 54(2): 229.     CrossRef
• Current status of newer generation endoscopic ultrasound core needles in the diagnostic evaluation of gastrointestinal lesions
  Amin K. Soltani, Kumar Krishnan
  Journal of the American Society of Cytopathology.2020; 9(5): 389.     CrossRef
• Present status and perspectives of endosonography 2017 in gastroenterology
  Michael Hocke, Barbara Braden, Christian Jenssen, Christoph F. Dietrich
  The Korean Journal of Internal Medicine.2018; 33(1): 36.     CrossRef
• Slow-Pull Using a Fanning Technique Is More Useful Than the Standard Suction Technique in EUS-Guided Fine Needle Aspiration in Pancreatic Masses
  Jae Min Lee, Hong Sik Lee, Jong Jin Hyun, Jung Min Lee, In Kyung Yoo, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim
  Gut and Liver.2018; 12(3): 360.     CrossRef
• Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions
  Ihab I. El Hajj, Howard Wu, Sarah Reuss, Melissa Randolph, Akeem Harris, Mark A. Gromski, Mohammad Al-Haddad
  Clinical Endoscopy.2018; 51(6): 576.     CrossRef
• EUS-guided liver biopsy for parenchymal disease: a comparison of diagnostic yield between two core biopsy needles
  Michael Sai Lai Sey, Mohammad Al-Haddad, Thomas F. Imperiale, Kathleen McGreevy, Jingmei Lin, John M. DeWitt
  Gastrointestinal Endoscopy.2016; 83(2): 347.     CrossRef
• Endoscopic ultrasound-guided techniques for diagnosing pancreatic mass lesions: Can we do better?
  Andrew C Storm, Linda S Lee
  World Journal of Gastroenterology.2016; 22(39): 8658.     CrossRef
• Yields and Utility of Endoscopic Ultrasonography-Guided 19-Gauge Trucut Biopsy versus 22-Gauge Fine Needle Aspiration for Diagnosing Gastric Subepithelial Tumors
  Hee Kyong Na, Jeong Hoon Lee, Young Soo Park, Ji Yong Ahn, Kwi-Sook Choi, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Jin-Ho Kim
  Clinical Endoscopy.2015; 48(2): 152.     CrossRef
• Tumor sólido pseudopapilar de páncreas con diagnóstico preoperatorio por ecoendoscopia
  María del Carmen García Gavilán, Isabel María Méndez Sánchez, Andrés Sánchez Yagüe, Luis Robles Cabeza, Ana M Betancourt Zambrano, Martha González Bárcenas, María Ángeles Romero Ordoñez, María del Carmen López Vega, Andrés Sánchez Cantos
  Gastroenterología y Hepatología.2015; 38(1): 42.     CrossRef
• Fine-Needle Biopsy: Should This Be the First Choice in Endoscopic Ultrasound-Guided Tissue Acquisition?
  Eun Young Kim
  Clinical Endoscopy.2014; 47(5): 425.     CrossRef
• What is the best method for endoscopic ultrasound-guided fine needle aspiration? Needle types and aspiration techniques
  Kazuo Hara, Nobumasa Mizuno, Susumu Hijioka, Hiroshi Imaoka, Masahiro Tajika, Tsutomu Tanaka, Makoto Ishihara, Yasumasa Niwa, Kenji Yamao
  Gastrointestinal Intervention.2014; 3(2): 104.     CrossRef

Schwannomas of the gastrointestinal (GI) tract are rare subepithelial tumors comprising approximately 3.3% to 12.8% of all mesenchymal tumors of the GI tract. On endoscopic ultrasound (EUS) they are seen as hypoechoic tumors arising most commonly from the 4th proper muscle layer. Although EUS helps to distinguish tumor characteristics, tissue sampling is required for differentiation with other more common tumors such as GI stromal tumors. Both EUS-guided fine needle aspiration and EUS-guided trucut biopsy (EUS-TCB) can be used for tissue sampling. However, only EUS-TCB allows core biopsy and a high yield of immunohistochemical staining. We report a case of a gastric schwannoma diagnosed by EUS-TCB.

Citations

Citations to this article as recorded by  

• Quadrangular space schwannoma affecting the axillary nerve
  Narottam Das, Pranathi Chandana, Manmeet Singh Chhabra, Praveen L. Basanagoudar
  Surgical Neurology International.2025; 16: 164.     CrossRef
• Differential diagnosis of submucosal gastric tumors: gastric schwannomas misdiagnosed as GISTs
  Mutlu Unver, Suleyman Cağlar Ertekin, Eyüp Kebapcı, Mustafa Olmez, Erhan Ergin, Safak Ozturk, Erkan Sahin, Ragıp Ortac
  Journal of Surgical Case Reports.2024;[Epub]     CrossRef
• What About Gastric Schwannoma? A Review Article
  Sara Lauricella, Sergio Valeri, Gianluca Mascianà, Ida Francesca Gallo, Erica Mazzotta, Chiara Pagnoni, Saponaro Costanza, Lorenza Falcone, Domenico Benvenuto, Marco Caricato, Gabriella Teresa Capolupo
  Journal of Gastrointestinal Cancer.2021; 52(1): 57.     CrossRef
• Intramuscular ancient schwannoma of the axillary nerve
  Vishali Moond, Preeti Diwaker, Reshma Golamari, Rohit Jain
  BMJ Case Reports.2021; 14(5): e239445.     CrossRef
• Gastric schwannoma: a case report and literature review
  Changsheng Pu, Keming Zhang
  Journal of International Medical Research.2020;[Epub]     CrossRef
• Gastric Schwannomas Misdiagnosed as GIST: A Comparative Study of Clinic Strategies Based on Membrane Marker Detection
  Quanyong Cheng, Kun Zhao, Jing Wang, Yu Guo, Hui Pang
  Journal of Cancer Research Updates.2020; 9(1): 82.     CrossRef
• Clinical characteristics and surgical treatment of schwannomas of the esophagus and stomach: A case series and systematic review
  Jesús Morales-Maza, Francisco Ulises Pastor-Sifuentes, Germán E Sánchez-Morales, Emilio Sanchez-Garcia Ramos, Oscar Santes, Uriel Clemente-Gutiérrez, Adriana Simoneta Pimienta-Ibarra, Heriberto Medina-Franco
  World Journal of Gastrointestinal Oncology.2019; 11(9): 750.     CrossRef
• Axillary schwannoma, preoperative diagnosis on a tru-cut biopsy: Case report and literature review
  Hager Aref, Georges A. Abizeid
  International Journal of Surgery Case Reports.2018; 52: 49.     CrossRef
• Spectral Computed Tomography Imaging of Gastric Schwannoma and Gastric Stromal Tumor
  Jianli Liu, Yanjun Chai, Junlin Zhou, Chi Dong, Wenjuan Zhang, Bin Liu
  Journal of Computer Assisted Tomography.2017; 41(3): 417.     CrossRef
• Role of endoscopic ultrasound and endoscopic resection for the treatment of gastric schwannoma
  Jinlong Hu, Xiang Liu, Nan Ge, Sheng Wang, Jintao Guo, Guoxin Wang, Siyu Sun
  Medicine.2017; 96(25): e7175.     CrossRef
• Two Synchronous Colonic Adenocarcinomas, a Gastric Schwannoma and a Mucinous Neoplasm of the Appendix: a Case Report
  Diogo Sousa, Miguel Allen, Alda Pinto, Andreia Ferreira, Ana Cruz, Diogo Marinho, Pierpaolo Cusati, José Augusto Martins
  Journal of Gastrointestinal Cancer.2015; 46(3): 304.     CrossRef
• Benign Gastric Schwannoma: How Long Should We Follow Up to Monitor the Recurrence? A Case Report and Comprehensive Review of Literature of 137 Cases
  Xiafei Hong, Wenming Wu, Mengyi Wang, Quan Liao, Yupei Zhao
  International Surgery.2015; 100(4): 744.     CrossRef