Korean Journal of Gastrointestinal Endoscopy 1997;17(6): 847-853.
증례 : 식도위장관 ; 염증성 장질환에 병발한 괴저성 농피증 2예 ( Case Reports : Esophagus , Stomach & Intestine ; Two Cases of Pyoderma Gangrenosum Associated with Inflammatory Bowel Diseases )
정성애, 양석균, 정훈용, 송병철, 장혜숙, 이상오, Mi Heun Lee, 김해련, 홍원선, 이영수, 민영일 (Sung Ae Jung, Suk Kyun Yang, Hwoon Yong Jung, Byeong Cheol Song, Hye Sook Chang, Sang Oh Lee, Hae Ryun Kim, Weon Seon Hong, Young Soo Lee and Young Il Min)
Abstract
Pyoderma gangrenosum is a painful, chronic, ulcerating skin disease of unknown cause. It commences as an erythematous papulopustule and rapidly evolves to form an area of frank ulceration with undermined, violaceous edges and a bright outer halo of erythema. Diagnosis is clinical, there being no accepted histological diagnostic criteria. An underlying systemic illness is present in more than 50 percent of patients. Pyoderma gangrenosum develops in 0.8-5.0 percent of patients with inflammatory bowel disease, which is the most frequent underlying disease of pyoderma gangrenosum. There is no report of pyoderma gangrenosum associated with Crohn's disease in Korea. We recently experienced two cases of pyoderma gangrenosum, a 52-year old man with Crohn's disease and a 30-year old man with ulcerative colitis. The cases are presented with the review of literature. (Korean J Gastrointest Endosc 17: 847-852, 1997)