Korean J Gastrointest Endosc > Volume 17(3); 1997 > Article
Korean Journal of Gastrointestinal Endoscopy 1997;17(3): 423-429.
증례 : 식도 위장관 ; 소장에 발생한 MALT 림프종 1예 ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Mucosa - associated Lymphoid Tissue Lymphoma in Small Intestine )
정인식, 정규원, 선희식, 김부성, 박수헌, 최명규, 김재광, 조세현, 최규용, 강창석, 김한욱, 오은숙, 한준열 (In Sik Chung, Kyu Won Chung, Hee Sik Sun, Boo Sung Kim, Soo Heon Park, Myung Gyu Choi, Jae Kwang Kim, Se Hyun Cho, Gyu Yong Choi, Chang Suk Kang, Han Wook Kim, Eun Sook Oh and Jun Yeul Han)
Mucosa-associated lymphoid tissue (MALT) lymphoma is the disease of distinctive clinicopathologic entities most of which are different from current lymph-node based lym- phoma classification. According to the circulatory properties of the lymphocytes and specific immunoglobulin isotype distribution, MALT is defined as the central lymphoid tissue and is opposed to peripheral somatic lymphoid tissue. It occurs most often in the gastrointestinal mucosa and the bronchial mucosa and may occur in other organs such as salivary gland, thyroid gland, conjunctiva, skin. The most common site of MALT lymphoma is gastrointestinal tract but non-gastrointestinal MALT lymphoma may present. The characteristics of pathology are reactive follicles surrounded by the diffuse infiltration of centrocyte-like (CCL) cells and lymphoepithelial lesion due to the gland invasion of CCL cells. It is a localized disease and has a long survival, Isaacson et al suggested the classification of primary gastrointestinal MALT lymphoma as low grade, high grade, immunoproliferative small intestinal disease (IPSID). The distribution is more often in the stomach than in the intestine. Intestinal MALT lymphomas have less favorable clinicnl courses than the gastric MALT lymphomas. Recurrences may appear in the same organ or in other extranodal sites. We report clinical, pathologic findings, and clinical course in a case of primary small intestinal MALT lymphoma in terminal ileum with literature review. (Korean J Gastrointest Endosc 17: 423-429, 1997)
Key Words: Primary gastrointestinal lymphorma , Mucosa - associated lymphoid tissue ( MALT ) , Centrocyte - like ( CCL ) cell
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