Korean Journal of Gastrointestinal Endoscopy 1998;18(4): 630-636.
증례 : 담도 췌장 ; 담낭관의 하부접합과 연관된 원발성 중복종양 1예 ( Case Reports : Biliary Tract & Pancreas ; A Case of Double Primary Cancer Associated with a Low Junction of the Cystic Duct )
김권수, 정선화, 김성진, 강승식, 계세협, 이진, 곽상택, 주상언, 박혜림, 손진희 (Gwon Soo Kim, Sun Hwa Jung, Seong Jin Kim, Seung Sik Kang, Sea Hyub Kae, Jin Lee, Sang Taek Kwak, Sang Aun Joo, Hye Rim Park and Jin Hee Sohn)
Abstract
Recently it has been discovered that anomalous union of pancreaticobiliary duct (AUPBD) may play an important role in the pathogenesis of bile duct cancer. Similar to this fact, there were a few reports on the clinical significance of the low junction of the cystic duct (LJCD). LJCD refers to the situation whereby the cystic duct enters the common duct at a low position between the upper margin of the pancreas and the duodenal opening of the bile duct. The pathogenetic mechanism in LJCD is similar to AUPBD in that the pancreatic juice refluxes to the bile duct, mixes with biles, and then generates the mutagens, which act as inflammatory substances and carcinogens on the epithelium of the bile duct. A 51-year-old male who experienced dyspepsia was hospitalized due to his abnormally functioning liver and dilated common bile duct. We confirmed primary cholangiocarcinoma on the common hepatic duct and gallbladder carcinoma associated with LJCD by ERCP and pathologic review of surgical specimen. We report a case of synchronous type double primary cancer associated with LJCD with a brief review of the literatures. (Korean J Gastrointest Endosc 18: 630-636, 1997)
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