Korean J Gastrointest Endosc > Volume 18(2); 1998 > Article
Korean Journal of Gastrointestinal Endoscopy 1998;18(2): 262-269.
증례 : 식도 위장관 ; Clostridium Perfringens 에 의한 위막성 대장염 1예 ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Pseudomembraneous Colitis by Clostridium Perfringens )
신재욱, 김호각, 이창형, 장성국, 이상채, 배정동, 전창호, 박재복 (Jae Uk Shin, Ho Gak Kim, Chang Hyeong Lee, Sung Gug Chang, Sang Chae Lee, Jung Dong Bae, Chang Ho Jeon and Jae Bok Park)
Abstract
A 62-year-old female was adrnitted to the Catholic University Hospital of Taegu-Hyosung with an intracerebral hemorrhage. She was operated on successfully, but developed bacterial pneumonia. She was then treated with sulperazone, tobramycin, and metronidazole for 1 month. After the antibiotic treatment, she suffered from a fever and bloody, mucoid diarrhea for 3 days, and was examined with a sigmoidoscope. The sigmoidoscopic examination revealed yellow patches of ulcerations and swelling covered with thick sero- sanguinous exudate in the distal transverse colon and sigmoid colon. A latex agglutination test for C. was performed on her stool, whereby difficile cytotoxin was negative, however, metronidazole resistant C. perfringens was isolated from anaerobic culture of the biopsied colon tissue. She recovered with 15 days using oral vancomycin treatment. The possibility of C. perfringens as a causative organism of pseuclomernbraneous colitis was discussed. (Korean J Gastrointest Endosc 18: 262-267, 1998)
Key Words: Pseudomembraneous colitis , C perfringens , Metronidazole
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