Korean Journal of Gastrointestinal Endoscopy 1999;19(6): 953-958.
당뇨병과 요독증에 병발한 위 모균증 1예 ( A Case of Gastric Mucormycosis Associated with Diabetes Mellitus and Uremia )
최욱렬(Wook Ryul Choi),임채남(Chae Nam Lim),원경헌(Kyung Heon Won),이상희(Sang Hee Lee),임선희(Seon Hee Lim),김나영(Na Young Kim),이계희(Kyu Heni Lee),최신은(Shin Eun Choi)
Abstract
Mucormycosis is an infection caused by fungi of the class Zygomycetes, order Mucorales. These are usual ubiquitous saprophytes but occasionally cause opportunistic infection in immunocompromised patients. Typically, these fungi invade blood vessels, and produce thrombosis and tissue infarction, so causing host fatality. These infections can be categorized into rhinocerebral, pulmonary, widely disseminated, gastrointestinal, cutaneous and miscellaneous form. Most of mucormycosis cases reported in Korea were rhinocerebral form except for three cases, which were gastrointestinal mucormycosis, accompanied with hematologic malignancy or immunosuppressing treatment. We experienced a 58-year-old male with gastric mucormycosis, who had diabetes and mild uremia without hematologic malignancy and immunosuppressive treatments. His chief complaints were abdominal pain and melena, and gastroscopy showed a 3 3 cm irregular edged ulcer considering malignancy. Its histological findings showed large, thin-walled, non-septate and right-angled branching fungal hyphae in necrotic tissue, diagnosed as mucormycosis. Finally he was dead due to severe hematemesis. (Korean J Gastrointest Endosc 19: 953∼958, 1999)