Abstract

Gastric squamous cell carcinoma is very rare and is termed both pure squamous cell carcinoma and adenosquamous cell carcinoma. The pathogenesis of this neoplasm remains obscure and theories vary widely. It tends to occur in the distal half of the stomach, frequently along the lesser curvature, and affects a slightly younger age group with a greater male preponderance compared to adenocarcinoma. One case of gastric squamous cell carcinoma and another case of gastric adenosquamous cell carcinoma is herein reported. In the first case, a 70-year old male was admitted as a result of epigastric pain. On endoscopy, abdominal CT and UGI, a huge fungating mass in the posterior wall of the antrum of the stomach was revealed. A subtotal gastrectomy with Billroth II anastomosis was performed. Unlike the endoscopic biopsy finding however, the histopathologic diagnosis determined a squamous cell carcinoma of the stomach. In the other case, a 64-year old male was admitted due to epigastric pain. Upon examination, a huge Borrmann type III tumor mass in the lower body and antrum of the stomach along the lesser curvature was seen. Endoscopic biopsy finding revealed a suspicious adenocarcinoma, and an operation was performed. Unlike the endoscopic biopsy finding however, the histopathologic diagnosis revealed a adenosquamous cell carcinoma of the stomach. (Korean J Gastrointest Endosc 19: 771∼775, 1999)

• Keywords: Squamous cell carcinoma, Adenosquamous cell carcinoma, Stomach