석준호, 박진철, 권순욱, 최진수, 김준환, 김영성, 김태년, 정문관 (Jun Ho Seok, Jin Chul Park, Soon Wook Kwun, Jin Soo Choi, Jun Hwan Kim, Yeung Sung Kim, Tae Nyun Kim and Mun Kwan Chung)
Abstract
Ulcerative colitis is an inflammatory disorder that affects the rectum and extends proximally to affect a variable extent of the colon. The major symptoms of ulcerative colitis include diarrhea, rectal bleeding, the passage of mucus, and abdominal pain. Ulcer-ative colitis also may be complicated by many local and systemic disorders as extrain-testinal manifestations. Pyoderma gangrenosum is the most severe dermatologic com-plication associated with ulcerative colitis. It is a painful , chronic, ulcerating skin disease of unknown cause. Diagnosis is clinical, there being no accepted histological diagnostic criteria. Conventional therapy is empirical, usually with high dose corticosteroids, but var-ious other agents have been tried with occasional success including topical antibiotics, cyclosporine, disodium cromoglycate, and dapsone. This patient was treated with high dose corticosteroid (prednisolone 1 mg/kg/day) and discharged with clinical improvement. So we report this case with a literature review. (Korean J Gastrointest Endosc 19: 300 ∼305, 1999)
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