Korean Journal of Gastrointestinal Endoscopy 1999;19(2): 275-280.
원발성 십이지장 유암종 (Carcinoid tumor) 1 예 (A Case of Primary Duodenal Carcinoid Tumor)
이정석, 홍수희, 유종훈, 최의혁, 권형주, 이무열, 박영우, 이철호, 김영묵, 이동윤, 황순철, 이준상 (Jeong Seok Lee, Soo Hee Hong, Jong Hoon Yoo, Eui Hyuk Choi, Hyung Joo Kwon, Moo Yeol Lee, Young Woo Park, Cheol Ho Lee, Young Mug Kim, Dong Yun Lee, Soon Chul Hwang and Joon Sang Lee)
Abstract
Carcinoid tumors are slow growing, rare neoplasms that arise from enterochromaffin cells, with malignant potential. Primary duodenal carcinoid tumors are rare, the reported incidence being 2.0 ∼8.9% of all gastrointestinal carcinoid tumors. Unless the carcinoid syndrome has developed, the non-specificity of the symptoms and physical findings, makes the clinical diagnosis of these tumors difficult. However, with the introduction of large and deep endoscopic biopsies, it is possible to diagnose duodenal carcinoid tumors at an early stage. Usually, local resection is the therapy of choice because of the very slow growth of the lesion and the low incidence of metastasis. Radical surgery is mandatory only in lesions more than 2 cm in diameter, or in the presence of muscular invasion. A 69-year-old female visited our medical department, having had symptoms of upper ab-dominal pain and intermittent melena for 1 week. Endoscopic examination showed 2.5 2.5 cm sized elevated mass lesion with central ulceration in the anterior wall side of the duodenal bulb. Immunohistochemical stains of the biopsy specimen showed that the tumor cells are positive reactivity for NSE (neuron-specific-enolase), chromogranin A, and cyto-keratin. (Korean J Gastrointest Endosc 19: 275 ∼280, 1999)
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